Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

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Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

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What functions are associated with Isopentenyl pyrophosphate?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Ding VD et al. Purification and characterization of recombinant human farnesyl diphosphate synthase expressed in Escherichia coli. 1991 Biochem. J. pmid:2018485
Shimizu S et al. Possible involvement of 3-hydroxymethylglutaryl-CoA reductase in determining the side-chain length of ubiquinone in rat heart. 1991 Arch. Biochem. Biophys. pmid:1846516
Schafer WR et al. Enzymatic coupling of cholesterol intermediates to a mating pheromone precursor and to the ras protein. 1990 Science pmid:2204115
Fujisaki S et al. Cloning and nucleotide sequence of the ispA gene responsible for farnesyl diphosphate synthase activity in Escherichia coli. 1990 J. Biochem. pmid:2089044
Mbaya B et al. Isoprenoid metabolism in Plasmodium falciparum during the intraerythrocytic phase of malaria. 1990 Biochem. Biophys. Res. Commun. pmid:2268347
Armstrong GA et al. Genetic and biochemical characterization of carotenoid biosynthesis mutants of Rhodobacter capsulatus. 1990 J. Biol. Chem. pmid:2159477
Yoshida I et al. Formation of a stable and catalytically active complex of the two essential components of hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26. 1989 Biochem. Biophys. Res. Commun. pmid:2541701
Fujisaki S et al. Isolation and characterization of an Escherichia coli mutant having temperature-sensitive farnesyl diphosphate synthase. 1989 J. Bacteriol. pmid:2676985
Ohnuma S et al. Kinetic studies on the prenyl chain elongation by undecaprenyl diphosphate synthase with artificial substrate homologues. 1989 FEBS Lett. pmid:2509247
Heide L and Berger U Partial purification and properties of geranyl pyrophosphate synthase from Lithospermum erythrorhizon cell cultures. 1989 Arch. Biochem. Biophys. pmid:2774555
Croteau R and Purkett PT Geranyl pyrophosphate synthase: characterization of the enzyme and evidence that this chain-length specific prenyltransferase is associated with monoterpene biosynthesis in sage (Salvia officinalis). 1989 Arch. Biochem. Biophys. pmid:2730002
Sagami H et al. The biosynthesis of dehydrodolichyl phosphates by rat liver microsomes. 1989 Biochim. Biophys. Acta pmid:2930770
Dennis MS and Light DR Rubber elongation factor from Hevea brasiliensis. Identification, characterization, and role in rubber biosynthesis. 1989 J. Biol. Chem. pmid:2681199
Anderson MS et al. Isopentenyl diphosphate:dimethylallyl diphosphate isomerase. An improved purification of the enzyme and isolation of the gene from Saccharomyces cerevisiae. 1989 J. Biol. Chem. pmid:2681212
Light DR and Dennis MS Purification of a prenyltransferase that elongates cis-polyisoprene rubber from the latex of Hevea brasiliensis. 1989 J. Biol. Chem. pmid:2808388
Light DR et al. Rubber elongation by farnesyl pyrophosphate synthases involves a novel switch in enzyme stereospecificity. 1989 J. Biol. Chem. pmid:2808389
Yoshida I et al. Protection of hexaprenyl-diphosphate synthase of Micrococcus luteus B-P 26 against inactivation by sulphydryl reagents and arginine-specific reagents. 1989 Biochim. Biophys. Acta pmid:2539196
Madhavan S et al. Stimulation of Isopentenyl Pyrophosphate Incorporation into Polyisoprene in Extracts from Guayule Plants (Parthenium argentatum Gray) by Low Temperature and 2-(3,4-Dichlorophenoxy) Triethylamine. 1989 Plant Physiol. pmid:16666574
Bruenger E and Rilling HC Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis. 1988 Anal. Biochem. pmid:3189812
Brinkhaus FL and Rilling HC Purification of geranylgeranyl diphosphate synthase from Phycomyces blakesleanus. 1988 Arch. Biochem. Biophys. pmid:3190245