Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

Cross Reference

Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Wang Y et al. The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome. 2008 J. Proteome Res. pmid:18303831
Srivastava A et al. Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target. 2008 Infect Disord Drug Targets pmid:18473904
Cummings JS et al. Impacts of HIV infection on Vgamma2Vdelta2 T cell phenotype and function: a mechanism for reduced tumor immunity in AIDS. 2008 J. Leukoc. Biol. pmid:18495780
Sgraja T et al. Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery. 2008 FEBS J. pmid:18422643
Martín JF et al. Conversion of beta-carotene into astaxanthin: Two separate enzymes or a bifunctional hydroxylase-ketolase protein? 2008 Microb. Cell Fact. pmid:18289382
Kuo CJ et al. Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases. 2008 J. Biomed. Biotechnol. pmid:18382620
Simoni D et al. Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism. 2008 J. Med. Chem. pmid:18937434
Spencer CT et al. Only a subset of phosphoantigen-responsive gamma9delta2 T cells mediate protective tuberculosis immunity. 2008 J. Immunol. pmid:18802050
Skorupinska-Tudek K et al. Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. 2008 J. Biol. Chem. pmid:18502754
Vandermoten S et al. Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity. 2008 FEBS Lett. pmid:18466770
Phillips MA et al. The Arabidopsis thaliana type I Isopentenyl Diphosphate Isomerases are targeted to multiple subcellular compartments and have overlapping functions in isoprenoid biosynthesis. 2008 Plant Cell pmid:18319397
Dupont FM Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. 2008 BMC Plant Biol. pmid:18419817
Alexander AA et al. Isopentenyl pyrophosphate-activated CD56+ {gamma}{delta} T lymphocytes display potent antitumor activity toward human squamous cell carcinoma. 2008 Clin. Cancer Res. pmid:18594005
Catusse J et al. Proteome-wide characterization of sugarbeet seed vigor and its tissue specific expression. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18635686
Inoue A et al. Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli. 2008 J. Bacteriol. pmid:18708495
de Ruyck J and Wouters J Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. 2008 Curr. Protein Pept. Sci. pmid:18393884
Opitz S et al. Increased terpenoid accumulation in cotton (Gossypium hirsutum) foliage is a general wound response. 2008 J. Chem. Ecol. pmid:18386096
Yoon SH et al. Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. 2007 May-Jun Biotechnol. Prog. pmid:17500531
Quinzii CM et al. Human coenzyme Q10 deficiency. 2007 Apr-May Neurochem. Res. pmid:17094036
Bock O et al. Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. 2007 Apr-Jun J Musculoskelet Neuronal Interact pmid:17627083
Moe M et al. Gene expression profiles in testis of pigs with extreme high and low levels of androstenone. 2007 BMC Genomics pmid:17988377
Walsh CT Revealing coupling patterns in isoprenoid alkylation biocatalysis. 2007 ACS Chem. Biol. pmid:17518430
Amslinger S et al. Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate. 2007 Immunobiology pmid:17270709
Christianson DW Chemistry. Roots of biosynthetic diversity. 2007 Science pmid:17412944
Matsumura Y et al. The carboxyl-terminal region of the geranylgeranyl diphosphate synthase is indispensable for the stabilization of the region involved in substrate binding and catalysis. 2007 J. Biochem. pmid:17846065
Nagaki M et al. Substrate specificities of wild and mutated farnesyl diphosphate synthases from Bacillus stearothermophilus with artificial substrates. 2007 Biosci. Biotechnol. Biochem. pmid:17617711
Mi J et al. Age-related subproteomic analysis of mouse liver and kidney peroxisomes. 2007 Proteome Sci pmid:18042274
Hoshino T and Eguchi T Functional analysis of type 1 isopentenyl diphosphate isomerase from Halobacterium sp. NRC-1. 2007 Biosci. Biotechnol. Biochem. pmid:17928693
Anisimova M et al. Phylogenomic analysis of natural selection pressure in Streptococcus genomes. 2007 BMC Evol. Biol. pmid:17760998
Sangar V et al. Quantitative sequence-function relationships in proteins based on gene ontology. 2007 BMC Bioinformatics pmid:17686158
Lodato P et al. Expression of the carotenoid biosynthesis genes in Xanthophyllomyces dendrorhous. 2007 Biol. Res. pmid:17657357
Murphy DJ and Brown JR Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. 2007 BMC Infect. Dis. pmid:17655757
Puan KJ et al. Preferential recognition of a microbial metabolite by human Vgamma2Vdelta2 T cells. 2007 Int. Immunol. pmid:17446209
Henriksson LM et al. Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. 2007 J. Biol. Chem. pmid:17491006
Rothman SC et al. Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species. 2007 Biochemistry pmid:17428035
Julsing MK et al. Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. 2007 Appl. Microbiol. Biotechnol. pmid:17458547
Glickman JF and Schmid A Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay. 2007 Assay Drug Dev Technol pmid:17477829
Saito K et al. Short-chain prenyl diphosphate synthase that condenses isopentenyl diphosphate with dimethylallyl diphosphate in ispA null Escherichia coli strain lacking farnesyl diphosphate synthase. 2007 J. Biosci. Bioeng. pmid:17630132
Klein-Marcuschamer D et al. Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene. 2007 Trends Biotechnol. pmid:17681626
Mönkkönen H et al. Zoledronic acid-induced IPP/ApppI production in vivo. 2007 Life Sci. pmid:17850825
Grimplet J et al. Tissue-specific mRNA expression profiling in grape berry tissues. 2007 BMC Genomics pmid:17584945
Towler MJ and Weathers PJ Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. 2007 Plant Cell Rep. pmid:17710406
Withers ST et al. Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. 2007 Appl. Environ. Microbiol. pmid:17693564
Wilcox CB et al. Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer. 2007 BMC Cancer pmid:18070364
Velasco R et al. A high quality draft consensus sequence of the genome of a heterozygous grapevine variety. 2007 PLoS ONE pmid:18094749
Buetow L et al. The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery. 2007 BMC Struct. Biol. pmid:17956607
Schirra F et al. Androgen influence on cholesterogenic enzyme mRNA levels in the mouse meibomian gland. 2007 Curr. Eye Res. pmid:17514523
Hebbeler AM et al. Individual Vgamma2-Jgamma1.2+ T cells respond to both isopentenyl pyrophosphate and Daudi cell stimulation: generating tumor effectors with low molecular weight phosphoantigens. 2007 Cancer Immunol. Immunother. pmid:17131122
Byres E et al. Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity. 2007 J. Mol. Biol. pmid:17583736
Kinjoh T et al. Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata. 2007 Insect Biochem. Mol. Biol. pmid:17628279