MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Plochocka D et al. | The role of ERG20 gene (encoding yeast farnesyl diphosphate synthase) mutation in long dolichol formation. Molecular modeling of FPP synthase. | 2000 | Biochimie | pmid:11018290 |
Zhang YW et al. | Chain length determination of prenyltransferases: both heteromeric subunits of medium-chain (E)-prenyl diphosphate synthase are involved in the product chain length determination. | 2000 | Biochemistry | pmid:11027152 |
Smit A and Mushegian A | Biosynthesis of isoprenoids via mevalonate in Archaea: the lost pathway. | 2000 | Genome Res. | pmid:11042147 |
Pan JJ et al. | Effect of site-directed mutagenesis of the conserved aspartate and glutamate on E. coli undecaprenyl pyrophosphate synthase catalysis. | 2000 | Biochemistry | pmid:11076526 |
Lange BM et al. | Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11078528 |
Ladygin VG | Biosynthesis of carotenoids in plastids of plants. | 2000 | Biochemistry Mosc. | pmid:11092953 |
Reed BC and Rilling HC | Crystallization and partial characterization of prenyltransferase from avian liver. | 1975 | Biochemistry | pmid:1109590 |
Fujikura K et al. | Significance of Asn-77 and Trp-78 in the catalytic function of undecaprenyl diphosphate synthase of Micrococcus luteus B-P 26. | 2000 | J. Biochem. | pmid:11098133 |
Olivier LM et al. | Identification of peroxisomal targeting signals in cholesterol biosynthetic enzymes. AA-CoA thiolase, hmg-coa synthase, MPPD, and FPP synthase. | 2000 | J. Lipid Res. | pmid:11108725 |
Vance DE and Van den Bosch H | Cholesterol in the year 2000. | 2000 | Biochim. Biophys. Acta | pmid:11111073 |