| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bergstrom JD et al. | Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase. | 2000 | Arch. Biochem. Biophys. | pmid:10620343 |
| Giron MD et al. | Isopentenoid synthesis in eukaryotic cells. An initiating role for post-translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1993 | Arch. Biochem. Biophys. | pmid:8097083 |
| Zhang YL and Li ZX | Functional analysis and molecular docking identify two active short-chain prenyltransferases in the green peach aphid, Myzus persicae. | 2012 | Arch. Insect Biochem. Physiol. | pmid:22696503 |
| Yokoi T et al. | Archaeal phospholipid biosynthetic pathway reconstructed in Escherichia coli. | 2012 | Archaea | pmid:22645416 |
| Triolo G et al. | Vgamma9/Vdelta2 T lymphocytes in Italian patients with Behçet's disease: evidence for expansion, and tumour necrosis factor receptor II and interleukin-12 receptor beta1 expression in active disease. | 2003 | Arthritis Res. Ther. | pmid:12932289 |
| Glickman JF and Schmid A | Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay. | 2007 | Assay Drug Dev Technol | pmid:17477829 |
| Mannen K et al. | Coordinated transcriptional regulation of isopentenyl diphosphate biosynthetic pathway enzymes in plastids by phytochrome-interacting factor 5. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24342623 |
| Fujiwara S et al. | Efficient synthesis of trans-polyisoprene compounds using two thermostable enzymes in an organic-aqueous dual-liquid phase system. | 2008 | Biochem. Biophys. Res. Commun. | pmid:17976371 |
| Noike M et al. | Product chain-length determination mechanism of Z,E-farnesyl diphosphate synthase. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18790692 |
| Fuse M et al. | Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways. | 2004 | Biochem. Biophys. Res. Commun. | pmid:14985133 |
| Runquist M et al. | Biosynthesis of trans,trans,trans-geranylgeranyl diphosphate by the cytosolic fraction from rat tissues. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1632765 |
| Koch G et al. | Posttranslational isoprenylation of rho protein is a prerequisite for its interaction with mastoparan and other amphiphilic agents. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1632782 |
| Mbaya B et al. | Isoprenoid metabolism in Plasmodium falciparum during the intraerythrocytic phase of malaria. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2268347 |
| Yoshida I et al. | Formation of a stable and catalytically active complex of the two essential components of hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2541701 |
| Lu YP et al. | Mechanism of cis-prenyltransferase reaction probed by substrate analogues. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20828539 |
| Gotoh T et al. | Different roles of the diphosphate moieties of allylic and homoallylic diphosphates in prenyltransferase reaction. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3178843 |
| Lu YP et al. | Different reaction mechanisms for cis- and trans-prenyltransferases. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19103164 |
| Ishii K et al. | Decaprenyl pyrophosphate synthetase from mitochondria of pig liver. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6651825 |
| de Ruyck J et al. | Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16269131 |
| Keller RK and Fliesler SJ | Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10600541 |