| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gräwert T et al. | Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19569147 |
| Tian L et al. | Transcript and proteomic analysis of developing white lupin (Lupinus albus L.) roots. | 2009 | BMC Plant Biol. | pmid:19123941 |
| Chung BK and Lee DY | Flux-sum analysis: a metabolite-centric approach for understanding the metabolic network. | 2009 | BMC Syst Biol | pmid:20021680 |
| Li X et al. | Epithelial Cell Gene Expression Induced by Intracellular Staphylococcus aureus. | 2009 | Int J Microbiol | pmid:20016671 |
| Cui Y et al. | Human gammadelta T cell recognition of lipid A is predominately presented by CD1b or CD1c on dendritic cells. | 2009 | Biol. Direct | pmid:19948070 |
| Gilg AB et al. | Unique animal prenyltransferase with monoterpene synthase activity. | 2009 | Naturwissenschaften | pmid:19277597 |
| Kumar S et al. | Comparative analysis of the complete sequence of the plastid genome of Parthenium argentatum and identification of DNA barcodes to differentiate Parthenium species and lines. | 2009 | BMC Plant Biol. | pmid:19917140 |
| Nymark M et al. | An integrated analysis of molecular acclimation to high light in the marine diatom Phaeodactylum tricornutum. | 2009 | PLoS ONE | pmid:19888450 |
| Simonsen HT et al. | Perspectives on using physcomitrella patens as an alternative production platform for thapsigargin and other terpenoid drug candidates. | 2009 | Perspect Medicin Chem | pmid:19812738 |
| King FW et al. | Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. | 2009 | PLoS ONE | pmid:19789631 |
| Urban EM et al. | Control of CD56 expression and tumor cell cytotoxicity in human Vgamma2Vdelta2 T cells. | 2009 | BMC Immunol. | pmid:19772585 |
| Ohto C et al. | Prenyl alcohol production by expression of exogenous isopentenyl diphosphate isomerase and farnesyl diphosphate synthase genes in Escherichia coli. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19129660 |
| Orlova I et al. | The small subunit of snapdragon geranyl diphosphate synthase modifies the chain length specificity of tobacco geranylgeranyl diphosphate synthase in planta. | 2009 | Plant Cell | pmid:20028839 |
| Paniagua-Michel J et al. | The carotenogenesis pathway via the isoprenoid-beta-carotene interference approach in a new strain of Dunaliella salina isolated from Baja California Mexico. | 2009 | Mar Drugs | pmid:19370170 |
| Vallabhaneni R and Wurtzel ET | Timing and biosynthetic potential for carotenoid accumulation in genetically diverse germplasm of maize. | 2009 | Plant Physiol. | pmid:19346441 |
| Liu Q et al. | Transcriptome analysis of a spontaneous mutant in sweet orange [Citrus sinensis (L.) Osbeck] during fruit development. | 2009 | J. Exp. Bot. | pmid:19218315 |
| Williams SL and Andrew McCammon J | Conformational dynamics of the flexible catalytic loop in Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase. | 2009 | Chem Biol Drug Des | pmid:19152632 |
| Xu Q et al. | Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant. | 2009 | BMC Genomics | pmid:19922663 |
| Bertalan M et al. | Complete genome sequence of the sugarcane nitrogen-fixing endophyte Gluconacetobacter diazotrophicus Pal5. | 2009 | BMC Genomics | pmid:19775431 |
| Kenny JG et al. | The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications. | 2009 | PLoS ONE | pmid:19183815 |
| Jawaid S et al. | Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). | 2009 | PLoS ONE | pmid:20011597 |
| Chang PK et al. | Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. | 2009 | Toxins (Basel) | pmid:22069533 |
| Wang W et al. | Global characterization of Artemisia annua glandular trichome transcriptome using 454 pyrosequencing. | 2009 | BMC Genomics | pmid:19818120 |
| Ganjewala D et al. | An account of cloned genes of Methyl-erythritol-4-phosphate pathway of isoprenoid biosynthesis in plants. | 2009 | Curr Issues Mol Biol | pmid:19193963 |
| Räikkönen J et al. | Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro. | 2009 | Br. J. Pharmacol. | pmid:19371349 |
| Vantourout P et al. | Specific requirements for Vgamma9Vdelta2 T cell stimulation by a natural adenylated phosphoantigen. | 2009 | J. Immunol. | pmid:19710470 |
| Li J et al. | Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells. | 2009 | J. Immunol. | pmid:19494338 |
| Mitrofan LM et al. | The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro. | 2009 | Bone | pmid:19699819 |
| Suzuki M et al. | Complete blockage of the mevalonate pathway results in male gametophyte lethality. | 2009 | J. Exp. Bot. | pmid:19363204 |
| Balibar CJ et al. | The mevalonate pathway of Staphylococcus aureus. | 2009 | J. Bacteriol. | pmid:19028897 |
| Campos Alberto EJ et al. | Differential effects of tumour necrosis factor-alpha and interleukin-12 on isopentenyl pyrophosphate-stimulated interferon-gamma production by cord blood Vgamma9 T cells. | 2009 | Immunology | pmid:19019091 |
| Lu YP et al. | Different reaction mechanisms for cis- and trans-prenyltransferases. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19103164 |
| Oswald E et al. | Reduced numbers of circulating gammadelta T cells in patients with bullous pemphigoid. | 2009 | Exp. Dermatol. | pmid:19469889 |
| Breccia P et al. | Thiopyrophosphoantigens: solid-phase synthesis and in vitro characterization of a new class of Vgamma9 Vdelta2 T cells activators. | 2009 | J. Med. Chem. | pmid:19453173 |
| Qin G et al. | Phosphoantigen-expanded human gammadelta T cells display potent cytotoxicity against monocyte-derived macrophages infected with human and avian influenza viruses. | 2009 | J. Infect. Dis. | pmid:19656068 |
| Riedel DJ et al. | Natural viral suppressors of HIV-1 have a unique capacity to maintain gammadelta T cells. | 2009 | AIDS | pmid:19609200 |
| Sillero MA et al. | Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. | 2009 | Biochem. Pharmacol. | pmid:19414000 |
| Kastenmüller G et al. | Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes. | 2009 | Genome Biol. | pmid:19284550 |
| Tsuruta H et al. | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | 2009 | PLoS ONE | pmid:19221601 |
| Sallaud C et al. | A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites. | 2009 | Plant Cell | pmid:19155349 |
| Lücker J et al. | Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation. | 2009 | BMC Genomics | pmid:19171055 |
| Correia DV et al. | Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. | 2009 | PLoS ONE | pmid:19479075 |
| Vinella D et al. | Iron-sulfur (Fe/S) protein biogenesis: phylogenomic and genetic studies of A-type carriers. | 2009 | PLoS Genet. | pmid:19478995 |
| Harada H et al. | Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli. | 2009 | Appl. Microbiol. Biotechnol. | pmid:18836713 |
| Ramsden NL et al. | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy. | 2009 | J. Med. Chem. | pmid:19320487 |
| Eberl M et al. | A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. | 2009 | PLoS Pathog. | pmid:19229322 |
| Unno H et al. | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. | 2009 | J. Biol. Chem. | pmid:19158086 |
| French CE | Synthetic biology and biomass conversion: a match made in heaven? | 2009 | J R Soc Interface | pmid:19454530 |
| Alagna F et al. | Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. | 2009 | BMC Genomics | pmid:19709400 |
| Whitaker JW et al. | The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes. | 2009 | Genome Biol. | pmid:19368726 |