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Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid biosynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon (Salmo salar). |
2008 |
BMC Genomics |
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Identification and functional analysis of light-responsive unique genes and gene family members in rice. |
2008 |
PLoS Genet. |
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Immunity, ageing and cancer. |
2008 |
Immun Ageing |
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Product chain-length determination mechanism of Z,E-farnesyl diphosphate synthase. |
2008 |
Biochem. Biophys. Res. Commun. |
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Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate. |
2008 |
Biochemistry |
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Identification of the genetic determinants of Salmonella enterica serotype Typhimurium that may regulate the expression of the type 1 fimbriae in response to solid agar and static broth culture conditions. |
2008 |
BMC Microbiol. |
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Jackson NM and Kocarek TA |
Suppression of CYP2B induction by alendronate-mediated farnesyl diphosphate synthase inhibition in primary cultured rat hepatocytes. |
2008 |
Drug Metab. Dispos. |
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The structural basis of chain length control in Rv1086. |
2008 |
J. Mol. Biol. |
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Impacts of HIV infection on Vgamma2Vdelta2 T cell phenotype and function: a mechanism for reduced tumor immunity in AIDS. |
2008 |
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Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism. |
2008 |
J. Med. Chem. |
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Spencer CT et al. |
Only a subset of phosphoantigen-responsive gamma9delta2 T cells mediate protective tuberculosis immunity. |
2008 |
J. Immunol. |
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Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. |
2008 |
J. Biol. Chem. |
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Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening. |
2008 |
BMC Genomics |
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Arimura G et al. |
Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling. |
2008 |
Planta |
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Isopentenyl pyrophosphate-activated CD56+ {gamma}{delta} T lymphocytes display potent antitumor activity toward human squamous cell carcinoma. |
2008 |
Clin. Cancer Res. |
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Catusse J et al. |
Proteome-wide characterization of sugarbeet seed vigor and its tissue specific expression. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
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Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli. |
2008 |
J. Bacteriol. |
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Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. |
2007 May-Jun |
Biotechnol. Prog. |
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Human coenzyme Q10 deficiency. |
2007 Apr-May |
Neurochem. Res. |
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Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. |
2007 Apr-Jun |
J Musculoskelet Neuronal Interact |
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Gene expression profiles in testis of pigs with extreme high and low levels of androstenone. |
2007 |
BMC Genomics |
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Yoon SH et al. |
Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. |
2007 |
Appl. Microbiol. Biotechnol. |
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An update on microbial carotenoid production: application of recent metabolic engineering tools. |
2007 |
Appl. Microbiol. Biotechnol. |
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Revealing coupling patterns in isoprenoid alkylation biocatalysis. |
2007 |
ACS Chem. Biol. |
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Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate. |
2007 |
Immunobiology |
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Christianson DW |
Chemistry. Roots of biosynthetic diversity. |
2007 |
Science |
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Matsumura Y et al. |
The carboxyl-terminal region of the geranylgeranyl diphosphate synthase is indispensable for the stabilization of the region involved in substrate binding and catalysis. |
2007 |
J. Biochem. |
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The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. |
2007 |
Immun Ageing |
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Nagaki M et al. |
Substrate specificities of wild and mutated farnesyl diphosphate synthases from Bacillus stearothermophilus with artificial substrates. |
2007 |
Biosci. Biotechnol. Biochem. |
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Mi J et al. |
Age-related subproteomic analysis of mouse liver and kidney peroxisomes. |
2007 |
Proteome Sci |
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Hoshino T and Eguchi T |
Functional analysis of type 1 isopentenyl diphosphate isomerase from Halobacterium sp. NRC-1. |
2007 |
Biosci. Biotechnol. Biochem. |
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Phylogenomic analysis of natural selection pressure in Streptococcus genomes. |
2007 |
BMC Evol. Biol. |
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Quantitative sequence-function relationships in proteins based on gene ontology. |
2007 |
BMC Bioinformatics |
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Expression of the carotenoid biosynthesis genes in Xanthophyllomyces dendrorhous. |
2007 |
Biol. Res. |
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Huang J and Gogarten JP |
Did an ancient chlamydial endosymbiosis facilitate the establishment of primary plastids? |
2007 |
Genome Biol. |
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Murphy DJ and Brown JR |
Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. |
2007 |
BMC Infect. Dis. |
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Na-Bangchang K et al. |
Pharmacokinetics and pharmacodynamics of fosmidomycin monotherapy and combination therapy with clindamycin in the treatment of multidrug resistant falciparum malaria. |
2007 |
Malar. J. |
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IDI2, a second isopentenyl diphosphate isomerase in mammals. |
2007 |
J. Biol. Chem. |
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New insights into the genetic regulation of Plasmodium falciparum obtained by Bayesian modeling. |
2007 |
Gene Regul Syst Bio |
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Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). |
2007 |
Phytochemistry |
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Kulaber A et al. |
Pro-inflammatory cellular immune response in Behçet's disease. |
2007 |
Rheumatol. Int. |
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Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. |
2007 |
BMC Struct. Biol. |
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Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei. |
2007 |
Cell Biol. Int. |
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Preferential recognition of a microbial metabolite by human Vgamma2Vdelta2 T cells. |
2007 |
Int. Immunol. |
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Henriksson LM et al. |
Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. |
2007 |
J. Biol. Chem. |
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Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species. |
2007 |
Biochemistry |
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Julsing MK et al. |
Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. |
2007 |
Appl. Microbiol. Biotechnol. |
pmid:17458547
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Glickman JF and Schmid A |
Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay. |
2007 |
Assay Drug Dev Technol |
pmid:17477829
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Saito K et al. |
Short-chain prenyl diphosphate synthase that condenses isopentenyl diphosphate with dimethylallyl diphosphate in ispA null Escherichia coli strain lacking farnesyl diphosphate synthase. |
2007 |
J. Biosci. Bioeng. |
pmid:17630132
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Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene. |
2007 |
Trends Biotechnol. |
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Zoledronic acid-induced IPP/ApppI production in vivo. |
2007 |
Life Sci. |
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Grimplet J et al. |
Tissue-specific mRNA expression profiling in grape berry tissues. |
2007 |
BMC Genomics |
pmid:17584945
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Towler MJ and Weathers PJ |
Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. |
2007 |
Plant Cell Rep. |
pmid:17710406
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Withers ST et al. |
Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. |
2007 |
Appl. Environ. Microbiol. |
pmid:17693564
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Wilcox CB et al. |
Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer. |
2007 |
BMC Cancer |
pmid:18070364
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Velasco R et al. |
A high quality draft consensus sequence of the genome of a heterozygous grapevine variety. |
2007 |
PLoS ONE |
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Buetow L et al. |
The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery. |
2007 |
BMC Struct. Biol. |
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Cassera MB et al. |
Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum. |
2007 |
Mem. Inst. Oswaldo Cruz |
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Androgen influence on cholesterogenic enzyme mRNA levels in the mouse meibomian gland. |
2007 |
Curr. Eye Res. |
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Hebbeler AM et al. |
Individual Vgamma2-Jgamma1.2+ T cells respond to both isopentenyl pyrophosphate and Daudi cell stimulation: generating tumor effectors with low molecular weight phosphoantigens. |
2007 |
Cancer Immunol. Immunother. |
pmid:17131122
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Byres E et al. |
Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity. |
2007 |
J. Mol. Biol. |
pmid:17583736
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Kinjoh T et al. |
Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata. |
2007 |
Insect Biochem. Mol. Biol. |
pmid:17628279
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Scott KM et al. |
The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2. |
2006 |
PLoS Biol. |
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Kloer DP et al. |
Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba. |
2006 |
Biochemistry |
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Gibon Y et al. |
Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes. |
2006 |
Genome Biol. |
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Thulasiram HV and Poulter CD |
Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity. |
2006 |
J. Am. Chem. Soc. |
pmid:17147392
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Forster AC and Church GM |
Towards synthesis of a minimal cell. |
2006 |
Mol. Syst. Biol. |
pmid:16924266
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Depasquale I and Wheatley DN |
Action of Lovastatin (Mevinolin) on an in vitro model of angiogenesis and its co-culture with malignant melanoma cell lines. |
2006 |
Cancer Cell Int. |
pmid:16573823
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Chang TH et al. |
Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination. |
2006 |
J. Biol. Chem. |
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Kharel Y et al. |
Manipulation of prenyl chain length determination mechanism of cis-prenyltransferases. |
2006 |
FEBS J. |
pmid:16420487
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Goffinet M et al. |
Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells. |
2006 |
BMC Cancer |
pmid:16539721
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Houde M et al. |
Wheat EST resources for functional genomics of abiotic stress. |
2006 |
BMC Genomics |
pmid:16772040
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Chemler JA et al. |
Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. |
2006 |
Microb. Cell Fact. |
pmid:16719921
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Kim SJ et al. |
Amplification of 1-deoxy-D-xyluose 5-phosphate (DXP) synthase level increases coenzyme Q10 production in recombinant Escherichia coli. |
2006 |
Appl. Microbiol. Biotechnol. |
pmid:16532312
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Workalemahu G et al. |
Expression of metalloproteinase-7 (matrilysin) in human blood and bronchoalveolar gamma/delta T-lymphocytes. Selective upregulation by the soluble non-peptidic mycobacterial phosphoantigen (isopentenyl pyrophosphate). |
2006 |
J. Cell. Physiol. |
pmid:16250011
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Zahiri HS et al. |
Coenzyme Q10 production in recombinant Escherichia coli strains engineered with a heterologous decaprenyl diphosphate synthase gene and foreign mevalonate pathway. |
2006 |
Metab. Eng. |
pmid:16815062
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Caccamo N et al. |
Sex-specific phenotypical and functional differences in peripheral human Vgamma9/Vdelta2 T cells. |
2006 |
J. Leukoc. Biol. |
pmid:16461739
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Scholte AA and Vederas JC |
Incorporation of deuterium-labelled analogs of isopentenyl diphosphate for the elucidation of the stereochemistry of rubber biosynthesis. |
2006 |
Org. Biomol. Chem. |
pmid:16467948
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Fischbach MA and Walsh CT |
Biochemistry. Directing biosynthesis. |
2006 |
Science |
pmid:17068249
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Theivagt AE et al. |
Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity. |
2006 |
Biochemistry |
pmid:17128979
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Zahiri HS et al. |
Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production. |
2006 |
Appl. Microbiol. Biotechnol. |
pmid:16896603
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Muñoz-Bertomeu J et al. |
Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender. |
2006 |
Plant Physiol. |
pmid:16980564
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Herzig C et al. |
Bovine T cell receptor gamma variable and constant genes: combinatorial usage by circulating gammadelta T cells. |
2006 |
Immunogenetics |
pmid:16541255
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Cervantes-Cervantes M et al. |
Maize cDNAs expressed in endosperm encode functional farnesyl diphosphate synthase with geranylgeranyl diphosphate synthase activity. |
2006 |
Plant Physiol. |
pmid:16581875
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Yoon SH et al. |
Enhanced lycopene production in Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate. |
2006 |
Biotechnol. Bioeng. |
pmid:16547999
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Maurice T et al. |
Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection. |
2006 |
Pharmacol. Biochem. Behav. |
pmid:16945406
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Grochowski LL et al. |
Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate. |
2006 |
J. Bacteriol. |
pmid:16621811
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Kavanagh KL et al. |
The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding. |
2006 |
J. Biol. Chem. |
pmid:16698791
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Hsiao YY et al. |
Comparison of transcripts in Phalaenopsis bellina and Phalaenopsis equestris (Orchidaceae) flowers to deduce monoterpene biosynthesis pathway. |
2006 |
BMC Plant Biol. |
pmid:16836766
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Thompson K et al. |
Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway. |
2006 |
Blood |
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Vadali RV et al. |
Enhanced lycopene productivity by manipulation of carbon flow to isopentenyl diphosphate in Escherichia coli. |
2005 Sep-Oct |
Biotechnol. Prog. |
pmid:16209562
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da Costa BM et al. |
Regulation of rubber biosynthetic rate and molecular weight in Hevea brasiliensis by metal cofactor. |
2005 Jan-Feb |
Biomacromolecules |
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Skewed representation of functionally distinct populations of Vgamma9Vdelta2 T lymphocytes in aging. |
2005 Jan-Feb |
Exp. Gerontol. |
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Wouters J et al. |
A crystallographic investigation of phosphoantigen binding to isopentenyl pyrophosphate/dimethylallyl pyrophosphate isomerase. |
2005 |
J. Am. Chem. Soc. |
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Guo RT et al. |
Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. |
2005 |
J. Biol. Chem. |
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Enterococcus faecalis phosphomevalonate kinase. |
2005 |
Protein Sci. |
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Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana. |
2005 |
Biosci. Biotechnol. Biochem. |
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Enfissi EM et al. |
Metabolic engineering of the mevalonate and non-mevalonate isopentenyl diphosphate-forming pathways for the production of health-promoting isoprenoids in tomato. |
2005 |
Plant Biotechnol. J. |
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Mahmud T et al. |
A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. |
2005 |
Chembiochem |
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Szkopińska A and Płochocka D |
Farnesyl diphosphate synthase; regulation of product specificity. |
2005 |
Acta Biochim. Pol. |
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