Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

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Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Liu YL et al. Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:24927548
Xi Y et al. [Amplification efficency and optimization of culture conditions of γδ T cells in peripheral blood by different phosphate compounds]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:25108442
Saxena B et al. Metabolic engineering of chloroplasts for artemisinic acid biosynthesis and impact on plant growth. 2014 J. Biosci. pmid:24499788
Banerjee A and Sharkey TD Methylerythritol 4-phosphate (MEP) pathway metabolic regulation. 2014 Nat Prod Rep pmid:24921065
Ebert R et al. Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells. 2014 Mol. Cancer pmid:25496233
Laurent AJ et al. Synergistic effects of ethanol and isopentenyl pyrophosphate on expansion of γδ T cells in synovial fluid from patients with arthritis. 2014 PLoS ONE pmid:25090614
Krasutsky SG et al. Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens. 2014 J. Org. Chem. pmid:25184438
Heider SA et al. IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum. 2014 FEBS J. pmid:25181035
Teufel R et al. One-pot enzymatic synthesis of merochlorin A and B. 2014 Angew. Chem. Int. Ed. Engl. pmid:25115835
Fox DT et al. Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2. 2014 PLoS ONE pmid:24751777
Wang H et al. Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human Vγ2Vδ2 T cells. 2013 J. Immunol. pmid:23833237
Vavassori S et al. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. 2013 Nat. Immunol. pmid:23872678
Gogoi D and Chiplunkar SV Targeting gamma delta T cells for cancer immunotherapy: bench to bedside. 2013 Indian J. Med. Res. pmid:24434328
Arens J et al. Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family. 2013 Chem. Commun. (Camb.) pmid:23295536
Ueno A et al. Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis. 2013 Parasitol. Int. pmid:23276703
Zhao L et al. Methylerythritol phosphate pathway of isoprenoid biosynthesis. 2013 Annu. Rev. Biochem. pmid:23746261
Zhou C et al. Isopentenyl diphosphate and dimethylallyl diphosphate/isopentenyl diphosphate ratio measured with recombinant isopentenyl diphosphate isomerase and isoprene synthase. 2013 Anal. Biochem. pmid:23747531
Chen X et al. Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. 2013 PLoS ONE pmid:24278153
Chang WC et al. Current development in isoprenoid precursor biosynthesis and regulation. 2013 Curr Opin Chem Biol pmid:23891475
Tong H et al. Quantitative determination of isopentenyl diphosphate in cultured mammalian cells. 2013 Anal. Biochem. pmid:23000003