| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bessoff K et al. | Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth. | 2013 | Antimicrob. Agents Chemother. | pmid:23380723 |
| Bowman JD et al. | Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box. | 2014 | Antimicrob. Agents Chemother. | pmid:24247137 |
| Testa CA and Johnson LJ | A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. | 2012 | Antimicrob. Agents Chemother. | pmid:22777049 |
| Ku B et al. | Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. | 2005 | Appl. Environ. Microbiol. | pmid:16269684 |
| Withers ST et al. | Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. | 2007 | Appl. Environ. Microbiol. | pmid:17693564 |
| Chou HH and Keasling JD | Synthetic pathway for production of five-carbon alcohols from isopentenyl diphosphate. | 2012 | Appl. Environ. Microbiol. | pmid:22941086 |
| Yoon SH et al. | Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115209 |
| Morrone D et al. | Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19777230 |
| Das A et al. | An update on microbial carotenoid production: application of recent metabolic engineering tools. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17912511 |
| Matthews PD and Wurtzel ET | Metabolic engineering of carotenoid accumulation in Escherichia coli by modulation of the isoprenoid precursor pool with expression of deoxyxylulose phosphate synthase. | 2000 | Appl. Microbiol. Biotechnol. | pmid:10803894 |
| Park YC et al. | Batch and fed-batch production of coenzyme Q10 in recombinant Escherichia coli containing the decaprenyl diphosphate synthase gene from Gluconobacter suboxydans. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15459799 |
| Cordero BF et al. | Enhancement of carotenoids biosynthesis in Chlamydomonas reinhardtii by nuclear transformation using a phytoene synthase gene isolated from Chlorella zofingiensis. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21519934 |
| Gallagher CE et al. | Surrogate biochemistry: use of Escherichia coli to identify plant cDNAs that impact metabolic engineering of carotenoid accumulation. | 2003 | Appl. Microbiol. Biotechnol. | pmid:12664151 |
| Tisch D and Schmoll M | Light regulation of metabolic pathways in fungi. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19915832 |
| Singkaravanit S et al. | Geranylgeranyl diphosphate synthase genes in entomopathogenic fungi. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19690851 |
| Julsing MK et al. | Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17458547 |
| Harada H et al. | Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli. | 2009 | Appl. Microbiol. Biotechnol. | pmid:18836713 |
| Kim SJ et al. | Amplification of 1-deoxy-D-xyluose 5-phosphate (DXP) synthase level increases coenzyme Q10 production in recombinant Escherichia coli. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16532312 |
| Cann AF and Liao JC | Pentanol isomer synthesis in engineered microorganisms. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19859707 |
| Zahiri HS et al. | Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16896603 |