Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

Cross Reference

Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Fujisaki S et al. Specific 14C-labeling of isoprenoids of intact E. coli cells. 1984 Biochem. Int. pmid:6383403
Sagami H et al. Effect of zinc ions on farnesyl pyrophosphate synthetase activity. 1984 Biochem. Int. pmid:6477628
Charon L et al. Deuterium-labelled isotopomers of 2-C-methyl-D-erythritol as tools for the elucidation of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis. 2000 Biochem. J. pmid:10698701
Disch A et al. Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714. 1998 Biochem. J. pmid:9657979
Tonhosolo R et al. Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum. 2005 Biochem. J. pmid:15984931
Zhou D and White RH Early steps of isoprenoid biosynthesis in Escherichia coli. 1991 Biochem. J. pmid:1996960
Ding VD et al. Purification and characterization of recombinant human farnesyl diphosphate synthase expressed in Escherichia coli. 1991 Biochem. J. pmid:2018485
Nave JF et al. Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. 1985 Biochem. J. pmid:2986604
Chen AP et al. Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase. 2005 Biochem. J. pmid:15447632
Tchaparian E et al. Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways. 2010 Biochem. J. pmid:20491655
Ishii K et al. A novel prenyltransferase from Paracoccus denitrificans. 1986 Biochem. J. pmid:3707524
Hirooka K et al. Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase. 2003 Biochem. J. pmid:12437513
Skilleter DN and Kekwick RG The enzymes forming isopentenyl pyrophosphate from 5-phosphomevalonate (mevalonate 5-phosphate) in the latex of Hevea brasiliensis. 1971 Biochem. J. pmid:4333851
Banthorpe DV and Le Patourel GN The biosynthesis of (+)- -pinene in Pinus species. 1972 Biochem. J. pmid:4656792
Thomas G and Threlfall DR Polyprenyl pyrophosphate-p-hydroxybenzoate polyprenyltransferase activity in mitochondria of broad-bean seeds and yeast. 1973 Biochem. J. pmid:4356126
Campos N et al. Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. 2001 Biochem. J. pmid:11115399
Milborrow BV Stereochemical aspects of the formation of double bonds in abscisic acid. 1972 Biochem. J. pmid:4643698
Rohmer M et al. Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. 1993 Biochem. J. pmid:8240251
Disch A et al. Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. 1998 Biochem. J. pmid:9531505
Hoeffler JF et al. Isoprenoid biosynthesis in higher plants and in Escherichia coli: on the branching in the methylerythritol phosphate pathway and the independent biosynthesis of isopentenyl diphosphate and dimethylallyl diphosphate. 2002 Biochem. J. pmid:12010124