| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:28577910 | ||||
| pmid:28631130 | ||||
| pmid:28669030 | ||||
| pmid:28695386 | ||||
| pmid:29143298 | ||||
| Sagami H et al. | The biosynthesis of dehydrodolichyl phosphates by rat liver microsomes. | 1989 | Biochim. Biophys. Acta | pmid:2930770 |
| Lee CS and O'Sullivan WJ | Improved procedures for the synthesis of phosphomevalonate and for the assay and purification of pig liver phosphomevalonate kinase. | 1985 | Biochim. Biophys. Acta | pmid:2983770 |
| Nave JF et al. | Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. | 1985 | Biochem. J. | pmid:2986604 |
| Davisson VJ et al. | Synthesis of allylic and homoallylic isoprenoid pyrophosphates. | 1985 | Meth. Enzymol. | pmid:2991702 |
| Reardon JE and Abeles RH | Mechanism of action of isopentenyl pyrophosphate isomerase: evidence for a carbonium ion intermediate. | 1986 | Biochemistry | pmid:3022798 |
| Ito M et al. | Stereochemical analysis of prenyltransferase reactions leading to (Z)- and (E)-polyprenyl chains. | 1987 | Biochemistry | pmid:3117106 |
| Gotoh T et al. | Different roles of the diphosphate moieties of allylic and homoallylic diphosphates in prenyltransferase reaction. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3178843 |
| Bruenger E and Rilling HC | Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis. | 1988 | Anal. Biochem. | pmid:3189812 |
| Brinkhaus FL and Rilling HC | Purification of geranylgeranyl diphosphate synthase from Phycomyces blakesleanus. | 1988 | Arch. Biochem. Biophys. | pmid:3190245 |
| Muehlbacher M and Poulter CD | Isopentenyl-diphosphate isomerase: inactivation of the enzyme with active-site-directed irreversible inhibitors and transition-state analogues. | 1988 | Biochemistry | pmid:3207678 |
| Adair WL and Cafmeyer N | Characterization of the Saccharomyces cerevisiae cis-prenyltransferase required for dolichyl phosphate biosynthesis. | 1987 | Arch. Biochem. Biophys. | pmid:3322197 |
| Mettal U et al. | Biosynthesis of monoterpene hydrocarbons by isolated chromoplasts from daffodil flowers. | 1988 | Eur. J. Biochem. | pmid:3338457 |
| Fujisaki S et al. | Biosynthesis of isoprenoids in intact cells of Escherichia coli. | 1986 | J. Biochem. | pmid:3519600 |
| Fujisaki S et al. | Isoprenoid synthesis in Escherichia coli. Separation and partial purification of four enzymes involved in the synthesis. | 1986 | J. Biochem. | pmid:3519603 |
| Reardon JE and Abeles RH | Inhibition of cholesterol biosynthesis by fluorinated mevalonate analogues. | 1987 | Biochemistry | pmid:3663621 |
| Ishii K et al. | A novel prenyltransferase from Paracoccus denitrificans. | 1986 | Biochem. J. | pmid:3707524 |
| Havel C et al. | Isopentenoid synthesis in isolated embryonic Drosophila cells. Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. | 1986 | J. Biol. Chem. | pmid:3733706 |
| Baba T et al. | Dehydrodolichyl diphosphate synthetase from rat seminiferous tubules. | 1987 | Arch. Biochem. Biophys. | pmid:3813545 |
| Spurgeon SL et al. | Biosynthesis of phytoene from isopentenyl pyrophosphate by a Neurospora enzyme system. | 1979 | Arch. Biochem. Biophys. | pmid:38745 |
| Laten HM et al. | An antisuppressor mutant of Saccharomyces cerevisiae deficient in isopentenylated tRNA has reduced delta 2-isopentenylpyrophosphate: tRNA-delta 2-isopentenyl transferase activity. | 1985 | FEBS Lett. | pmid:3881278 |
| Baba T et al. | Photoaffinity labeling of undecaprenyl pyrophosphate synthetase with a farnesyl pyrophosphate analogue. | 1985 | J. Biol. Chem. | pmid:3897217 |
| Allen CM and Baba T | Photolabile analogs of the allylic pyrophosphate substrate of prenyltransferases. | 1985 | Meth. Enzymol. | pmid:4021809 |
| Barnard GF | Prenyltransferase from human liver. | 1985 | Meth. Enzymol. | pmid:4021811 |
| Gonzalez-Pacanowska D et al. | Role of mevalonate-5-pyrophosphate decarboxylase in the regulation of chick intestinal cholesterogenesis. | 1985 | Biochim. Biophys. Acta | pmid:4038608 |
| Watson JA et al. | Isoprenoid synthesis in isolated embryonic Drosophila cells. Sterol-independent regulatory signal molecule is distal to isopentenyl 1-pyrophosphates. | 1985 | J. Biol. Chem. | pmid:4055772 |
| Koyama T et al. | Isoprenoid enzyme systems of silkworm. I. Partial purification of isopentenyl pyrophosphate isomerase, farnesyl pyrophosphate synthetase, and geranylgeranyl pyrophosphate synthetase. | 1985 | J. Biochem. | pmid:4066649 |
| Koyama T et al. | Isoprenoid enzyme systems of silkworm. II. Formation of the juvenile hormone skeletons by farnesyl pyrophosphate synthetase II. | 1985 | J. Biochem. | pmid:4066650 |
| Popják G and Hadley C | Inhibition of liver prenyltransferase by citronellyl and geranyl phosphonate and phosphonylphosphate. | 1985 | J. Lipid Res. | pmid:4067435 |
| Skilleter DN and Kekwick RG | The enzymes forming isopentenyl pyrophosphate from 5-phosphomevalonate (mevalonate 5-phosphate) in the latex of Hevea brasiliensis. | 1971 | Biochem. J. | pmid:4333851 |
| Momose K and Rudney H | 3-Polyprenyl-4-hydroxybenzoate synthesis in the inner membrane of mitochondria from p-hydroxybenzoate and isopentenylpyrophosphate. A demonstration of isoprenoid synthesis in rat liver mitochondria. | 1972 | J. Biol. Chem. | pmid:4338233 |
| Thomas G and Threlfall DR | Polyprenyl pyrophosphate-p-hydroxybenzoate polyprenyltransferase activity in mitochondria of broad-bean seeds and yeast. | 1973 | Biochem. J. | pmid:4356126 |
| Koyama T et al. | Studies on isopentenyl pyrophosphate isomerase with artificial substrates. | 1973 | J. Biol. Chem. | pmid:4356618 |
| Jedlicki E et al. | Stereospecificity of isopentenylpyrophosphate isomerase and prenyl transferase from pinus and citrus. | 1972 | Arch. Biochem. Biophys. | pmid:4635785 |
| Milborrow BV | Stereochemical aspects of the formation of double bonds in abscisic acid. | 1972 | Biochem. J. | pmid:4643698 |
| Banthorpe DV and Le Patourel GN | The biosynthesis of (+)- -pinene in Pinus species. | 1972 | Biochem. J. | pmid:4656792 |
| Poulter CD and Satterwhite DM | Mechanism of the prenyl-transfer reaction. Studies with (E)- and (Z)-3-trifluoromethyl-2-buten-1-yl pyrophosphate. | 1977 | Biochemistry | pmid:562673 |
| Koyama T et al. | Two forms of farnesyl pyrophosphate synthetase from hog liver. | 1977 | J. Biochem. | pmid:599144 |
| Kreuz K and Kleinig H | Synthesis of prenyl lipids in cells of spinach leaf. Compartmentation of enzymes for formation of isopentenyl diphosphate. | 1984 | Eur. J. Biochem. | pmid:6086332 |
| Block MA et al. | Site of synthesis of geranylgeraniol derivatives in intact spinach chloroplasts. | 1980 | Biochim. Biophys. Acta | pmid:6249390 |
| Rossignol DP et al. | Metabolic interconversion of dolichol and dolichyl phosphate during development of the sea urchin embryo. | 1983 | J. Biol. Chem. | pmid:6307993 |
| Spurgeon SL et al. | Isopentenyl pyrophosphate isomerase and prenyltransferase from tomato fruit plastids. | 1984 | Arch. Biochem. Biophys. | pmid:6324686 |
| Fujisaki S et al. | Specific 14C-labeling of isoprenoids of intact E. coli cells. | 1984 | Biochem. Int. | pmid:6383403 |
| Nakanishi S et al. | Preparation of 14C-labeled and unlabeled sterol intermediates from yeast using metabolic inhibitors. | 1984 | J. Biochem. | pmid:6397465 |
| Sagami H et al. | Effect of zinc ions on farnesyl pyrophosphate synthetase activity. | 1984 | Biochem. Int. | pmid:6477628 |
| Sagami H and Ogura K | Multiple forms of isopentenyl pyrophosphate isomerase of avian liver. | 1983 | J. Biochem. | pmid:6643431 |