Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

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Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

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What functions are associated with Isopentenyl pyrophosphate?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Lin YS et al. Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells. 2012 J. Med. Chem. pmid:22390415
Holte D et al. An approach to mimicking the sesquiterpene cyclase phase by nickel-promoted diene/alkyne cooligomerization. 2012 J. Org. Chem. pmid:22229741
Mabanglo MF et al. The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase. 2012 Biochemistry pmid:22148590
Park J et al. Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. 2012 BMC Struct. Biol. pmid:23234314
Van Laar TA et al. Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi. 2012 PLoS ONE pmid:22675445
Liu D et al. The genome of Ganoderma lucidum provides insights into triterpenes biosynthesis and wood degradation [corrected]. 2012 PLoS ONE pmid:22567134
Yang J et al. Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. 2012 PLoS ONE pmid:22558074
Span I et al. Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis. 2012 J. Mol. Biol. pmid:22137895
Angaman DM et al. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. 2012 Plant Methods pmid:22243738
Xu W et al. A closer look at the spectroscopic properties of possible reaction intermediates in wild-type and mutant (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase. 2012 Biochemistry pmid:22646150
Testa CA and Johnson LJ A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. 2012 Antimicrob. Agents Chemother. pmid:22777049
Nakatani H et al. Substrate-induced change in the quaternary structure of type 2 isopentenyl diphosphate isomerase from Sulfolobus shibatae. 2012 J. Bacteriol. pmid:22505674
Nagel R et al. Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry. 2012 Anal. Biochem. pmid:22266300
Green SA et al. Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis). 2012 J. Exp. Bot. pmid:22162874
Zhang YL and Li ZX Functional analysis and molecular docking identify two active short-chain prenyltransferases in the green peach aphid, Myzus persicae. 2012 Arch. Insect Biochem. Physiol. pmid:22696503
Span I et al. Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. 2012 Nat Commun pmid:22948824
Bitok JK and Meyers CF 2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity. 2012 ACS Chem. Biol. pmid:22839733
Diaz ME et al. Characterization of an isopentenyl diphosphate isomerase involved in the juvenile hormone pathway in Aedes aegypti. 2012 Insect Biochem. Mol. Biol. pmid:22782071
Kuzuyama T and Seto H Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis. 2012 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:22450534
Dozier JK and Distefano MD An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases. 2012 Anal. Biochem. pmid:22085443
Caballero MC et al. Characterization of acyl carrier protein and LytB in Babesia bovis apicoplast. 2012 Mol. Biochem. Parasitol. pmid:22057350
Ariyawutthiphan O et al. Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation. 2012 Acta Crystallogr. D Biol. Crystallogr. pmid:23090405
Lamsen EN and Atsumi S Recent progress in synthetic biology for microbial production of C3-C10 alcohols. 2012 Front Microbiol pmid:22701113
Chow KS et al. Metabolic routes affecting rubber biosynthesis in Hevea brasiliensis latex. 2012 J. Exp. Bot. pmid:22162870
Aros D et al. Volatile emissions of scented Alstroemeria genotypes are dominated by terpenes, and a myrcene synthase gene is highly expressed in scented Alstroemeria flowers. 2012 J. Exp. Bot. pmid:22268153
Rad SA et al. Type 2 IDI performs better than type 1 for improving lycopene production in metabolically engineered E. coli strains. 2012 World J. Microbiol. Biotechnol. pmid:22806807
Fatima T et al. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. 2012 PLoS ONE pmid:22558083
Kumar M et al. Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. 2012 Exp Diabetes Res pmid:22611376
Barta ML et al. Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. 2012 Biochemistry pmid:22734632
Tidten-Luksch N et al. IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening. 2012 PLoS ONE pmid:22563402
Poonia B and Pauza CD Gamma delta T cells from HIV+ donors can be expanded in vitro by zoledronate/interleukin-2 to become cytotoxic effectors for antibody-dependent cellular cytotoxicity. 2012 Cytotherapy pmid:22029653
Teng KH and Liang PH Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: a cis-prenyltransferase for bacterial peptidoglycan biosynthesis. 2012 Bioorg. Chem. pmid:21993493
Chou HH and Keasling JD Synthetic pathway for production of five-carbon alcohols from isopentenyl diphosphate. 2012 Appl. Environ. Microbiol. pmid:22941086
Cornish K and Xie W Natural rubber biosynthesis in plants: rubber transferase. 2012 Meth. Enzymol. pmid:22999170
Guirimand G et al. Triple subcellular targeting of isopentenyl diphosphate isomerases encoded by a single gene. 2012 Plant Signal Behav pmid:22951398
Zhang J et al. Modeling studies with Helicobacter pylori octaprenyl pyrophosphate synthase reveal the enzymatic mechanism of trans-prenyltransferases. 2012 Int. J. Biochem. Cell Biol. pmid:22982238
Post J et al. Laticifer-specific cis-prenyltransferase silencing affects the rubber, triterpene, and inulin content of Taraxacum brevicorniculatum. 2012 Plant Physiol. pmid:22238421
Suzuki N et al. Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver. 2012 Planta pmid:22729820
Raina M et al. Association of a multi-synthetase complex with translating ribosomes in the archaeon Thermococcus kodakarensis. 2012 FEBS Lett. pmid:22683511
Ma YG et al. Activation of BK(Ca) channels in zoledronic acid-induced apoptosis of MDA-MB-231 breast cancer cells. 2012 PLoS ONE pmid:22655048
Jonnalagadda V et al. Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction. 2012 J. Am. Chem. Soc. pmid:22471428
Wurtzel ET et al. Maize provitamin a carotenoids, current resources, and future metabolic engineering challenges. 2012 Front Plant Sci pmid:22645578
Teng KH and Liang PH Undecaprenyl diphosphate synthase, a cis-prenyltransferase synthesizing lipid carrier for bacterial cell wall biosynthesis. 2012 Mol. Membr. Biol. pmid:22471620
Yokoi T et al. Archaeal phospholipid biosynthetic pathway reconstructed in Escherichia coli. 2012 Archaea pmid:22645416
Förster F et al. Transcriptome analysis in tardigrade species reveals specific molecular pathways for stress adaptations. 2012 Bioinform Biol Insights pmid:22563243
Berthelot K et al. Isopentenyl diphosphate isomerase: A checkpoint to isoprenoid biosynthesis. 2012 Biochimie pmid:22503704
Wan L et al. De novo transcriptomic analysis of an oleaginous microalga: pathway description and gene discovery for production of next-generation biofuels. 2012 PLoS ONE pmid:22536352
Mabanglo MF et al. Mutagenesis of isopentenyl phosphate kinase to enhance geranyl phosphate kinase activity. 2012 ACS Chem. Biol. pmid:22533411
Bendersky A et al. Cellular interactions of synovial fluid γδ T cells in juvenile idiopathic arthritis. 2012 J. Immunol. pmid:22450805
Lei A et al. Expression of fatty acid synthesis genes and fatty acid accumulation in haematococcus pluvialis under different stressors. 2012 Biotechnol Biofuels pmid:22448811