Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

Cross Reference

Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Liu T and Khosla C Chemistry. A balancing act for Taxol precursor pathways in E. coli. 2010 Science pmid:20929799
Ajikumar PK et al. Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli. 2010 Science pmid:20929806
Christianson DW Chemistry. Roots of biosynthetic diversity. 2007 Science pmid:17412944
Schafer WR et al. Enzymatic coupling of cholesterol intermediates to a mating pheromone precursor and to the ras protein. 1990 Science pmid:2204115
Jomaa H et al. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. 1999 Science pmid:10477522
Zhao Y et al. cDNA cloning, chromosome mapping and expression characterization of human geranylgeranyl pyrophosphate synthase. 2000 Sci. China, C, Life Sci. pmid:18726356
Tardoski S et al. Low-intensity continuous ultrasound triggers effective bisphosphonate anticancer activity in breast cancer. 2015 Sci Rep pmid:26578234
Umeda T et al. Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum. 2011 Sci Rep pmid:22355528
Kulaber A et al. Pro-inflammatory cellular immune response in Behçet's disease. 2007 Rheumatol. Int. pmid:17549482
Morita CT et al. Direct presentation of non-peptide prenyl pyrophosphate antigens to human gamma delta T cells. 1996 Res. Immunol. pmid:8876064