Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

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Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Spurgeon SL et al. Biosynthesis of phytoene from isopentenyl pyrophosphate by a Neurospora enzyme system. 1979 Arch. Biochem. Biophys. pmid:38745
Baba T et al. Dehydrodolichyl diphosphate synthetase from rat seminiferous tubules. 1987 Arch. Biochem. Biophys. pmid:3813545
Havel C et al. Isopentenoid synthesis in isolated embryonic Drosophila cells. Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. 1986 J. Biol. Chem. pmid:3733706
Ishii K et al. A novel prenyltransferase from Paracoccus denitrificans. 1986 Biochem. J. pmid:3707524
Reardon JE and Abeles RH Inhibition of cholesterol biosynthesis by fluorinated mevalonate analogues. 1987 Biochemistry pmid:3663621
Fujisaki S et al. Isoprenoid synthesis in Escherichia coli. Separation and partial purification of four enzymes involved in the synthesis. 1986 J. Biochem. pmid:3519603
Fujisaki S et al. Biosynthesis of isoprenoids in intact cells of Escherichia coli. 1986 J. Biochem. pmid:3519600
Mettal U et al. Biosynthesis of monoterpene hydrocarbons by isolated chromoplasts from daffodil flowers. 1988 Eur. J. Biochem. pmid:3338457
Adair WL and Cafmeyer N Characterization of the Saccharomyces cerevisiae cis-prenyltransferase required for dolichyl phosphate biosynthesis. 1987 Arch. Biochem. Biophys. pmid:3322197
Muehlbacher M and Poulter CD Isopentenyl-diphosphate isomerase: inactivation of the enzyme with active-site-directed irreversible inhibitors and transition-state analogues. 1988 Biochemistry pmid:3207678
Brinkhaus FL and Rilling HC Purification of geranylgeranyl diphosphate synthase from Phycomyces blakesleanus. 1988 Arch. Biochem. Biophys. pmid:3190245
Bruenger E and Rilling HC Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis. 1988 Anal. Biochem. pmid:3189812
Gotoh T et al. Different roles of the diphosphate moieties of allylic and homoallylic diphosphates in prenyltransferase reaction. 1988 Biochem. Biophys. Res. Commun. pmid:3178843
Ito M et al. Stereochemical analysis of prenyltransferase reactions leading to (Z)- and (E)-polyprenyl chains. 1987 Biochemistry pmid:3117106
Reardon JE and Abeles RH Mechanism of action of isopentenyl pyrophosphate isomerase: evidence for a carbonium ion intermediate. 1986 Biochemistry pmid:3022798
Davisson VJ et al. Synthesis of allylic and homoallylic isoprenoid pyrophosphates. 1985 Meth. Enzymol. pmid:2991702
Nave JF et al. Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. 1985 Biochem. J. pmid:2986604
Lee CS and O'Sullivan WJ Improved procedures for the synthesis of phosphomevalonate and for the assay and purification of pig liver phosphomevalonate kinase. 1985 Biochim. Biophys. Acta pmid:2983770
Sagami H et al. The biosynthesis of dehydrodolichyl phosphates by rat liver microsomes. 1989 Biochim. Biophys. Acta pmid:2930770
pmid:29143298