| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Forsea AM et al. | Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells. | 2004 | Br. J. Cancer | pmid:15280922 |
| Sutherlin A and Rodwell VW | Multienzyme mevalonate pathway bioreactor. | 2004 | Biotechnol. Bioeng. | pmid:15286992 |
| Zgani I et al. | Synthesis of prenyl pyrophosphonates as new potent phosphoantigens inducing selective activation of human Vgamma9Vdelta2 T lymphocytes. | 2004 | J. Med. Chem. | pmid:15317470 |
| Song Y et al. | Synthesis of chiral phosphoantigens and their activity in gamma delta T cell stimulation. | 2004 | Bioorg. Med. Chem. Lett. | pmid:15357974 |
| Boylston WH et al. | Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice. | 2004 | Aging Cell | pmid:15379852 |
| Rohdich F et al. | Perspectives in anti-infective drug design. The late steps in the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate. | 2004 | Bioorg. Chem. | pmid:15381396 |
| pmid:15388934 | ||||
| Chen AP et al. | Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase. | 2005 | Biochem. J. | pmid:15447632 |
| Botella-PavÃa P et al. | Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors. | 2004 | Plant J. | pmid:15447646 |
| Seker T et al. | Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15448940 |
| Ling S et al. | Genoprotective pathways. II. Attenuation of oxidative DNA damage by isopentenyl diphosphate. | 2004 | Mutat. Res. | pmid:15450402 |
| Xiong X et al. | Identification of guinea pig gammadelta T cells and characterization during pulmonary tuberculosis. | 2004 | Vet. Immunol. Immunopathol. | pmid:15451613 |
| Cassera MB et al. | The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum. | 2004 | J. Biol. Chem. | pmid:15452112 |
| Park YC et al. | Batch and fed-batch production of coenzyme Q10 in recombinant Escherichia coli containing the decaprenyl diphosphate synthase gene from Gluconobacter suboxydans. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15459799 |
| pmid:15464154 | ||||
| pmid:15469281 | ||||
| pmid:15474569 | ||||
| Nagaki M et al. | Substrate specificities of several prenyl chain elongating enzymes with respect to 4-methyl-4-pentenyl diphosphate. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15502351 |
| Wille A et al. | Sparse graphical Gaussian modeling of the isoprenoid gene network in Arabidopsis thaliana. | 2004 | Genome Biol. | pmid:15535868 |
| pmid:15541397 | ||||
| pmid:15542379 | ||||
| Engprasert S et al. | Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq. | 2004 | BMC Plant Biol. | pmid:15550168 |
| Raschke M et al. | A high-performance liquid chromatography method for the analysis of intermediates of the deoxyxylulose phosphate pathway. | 2004 | Anal. Biochem. | pmid:15556562 |
| Barkley SJ et al. | Proton exchange in type II isopentenyl diphosphate isomerase. | 2004 | Org. Lett. | pmid:15606125 |
| pmid:15608374 | ||||
| Conti L et al. | Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gammadelta T cells: role of CD86 and inflammatory cytokines. | 2005 | J. Immunol. | pmid:15611247 |
| Inomata M et al. | Biosynthesis of abscisic acid by the direct pathway via ionylideneethane in a fungus, Cercospora cruenta. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15618629 |
| Mahmud T et al. | A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. | 2005 | Chembiochem | pmid:15619721 |
| Dudareva N et al. | The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15630092 |
| da Costa BM et al. | Regulation of rubber biosynthetic rate and molecular weight in Hevea brasiliensis by metal cofactor. | 2005 Jan-Feb | Biomacromolecules | pmid:15638531 |
| Wouters J et al. | A crystallographic investigation of phosphoantigen binding to isopentenyl pyrophosphate/dimethylallyl pyrophosphate isomerase. | 2005 | J. Am. Chem. Soc. | pmid:15643873 |
| pmid:15650872 | ||||
| Guevara-GarcÃa A et al. | Characterization of the Arabidopsis clb6 mutant illustrates the importance of posttranscriptional regulation of the methyl-D-erythritol 4-phosphate pathway. | 2005 | Plant Cell | pmid:15659625 |
| Re F et al. | Skewed representation of functionally distinct populations of Vgamma9Vdelta2 T lymphocytes in aging. | 2005 Jan-Feb | Exp. Gerontol. | pmid:15664733 |
| Flügge UI and Gao W | Transport of isoprenoid intermediates across chloroplast envelope membranes. | 2005 | Plant Biol (Stuttg) | pmid:15666208 |
| Lutz RJ et al. | Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation. | 1992 | J. Biol. Chem. | pmid:1569056 |
| Becker SA and Palsson BØ | Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N315: an initial draft to the two-dimensional annotation. | 2005 | BMC Microbiol. | pmid:15752426 |
| pmid:15765206 | ||||
| Hirooka K et al. | Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15784989 |
| Guo RT et al. | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. | 2005 | J. Biol. Chem. | pmid:15788389 |
| Doun SS et al. | Enterococcus faecalis phosphomevalonate kinase. | 2005 | Protein Sci. | pmid:15802646 |
| Fujisaki S et al. | Disruption of the structural gene for farnesyl diphosphate synthase in Escherichia coli. | 2005 | J. Biochem. | pmid:15809342 |
| Szkopińska A and Płochocka D | Farnesyl diphosphate synthase; regulation of product specificity. | 2005 | Acta Biochim. Pol. | pmid:15827605 |
| Kamińska J et al. | Rsp5 ubiquitin ligase affects isoprenoid pathway and cell wall organization in S. cerevisiae. | 2005 | Acta Biochim. Pol. | pmid:15827618 |
| Chen L et al. | Transcriptional profiling of gamma delta T cells identifies a role for vitamin D in the immunoregulation of the V gamma 9V delta 2 response to phosphate-containing ligands. | 2005 | J. Immunol. | pmid:15879110 |
| pmid:15882994 | ||||
| Cairo C et al. | The Vgamma2/Vdelta2 T-cell repertoire in Macaca fascicularis: functional responses to phosphoantigen stimulation by the Vgamma2/Jgamma1.2 subset. | 2005 | Immunology | pmid:15885125 |
| Kang MJ et al. | Identification of genes affecting lycopene accumulation in Escherichia coli using a shot-gun method. | 2005 | Biotechnol. Bioeng. | pmid:15898075 |
| Martino A et al. | Complementary function of gamma delta T-lymphocytes and dendritic cells in the response to isopentenyl-pyrophosphate and lipopolysaccharide antigens. | 2005 | J. Clin. Immunol. | pmid:15981088 |
| pmid:15981409 |