Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

Cross Reference

Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Riebeling C et al. The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro. 2002 Br. J. Cancer pmid:12177810
Ershov YV et al. Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate. 2002 J. Bacteriol. pmid:12193620
Adam P et al. Biosynthesis of terpenes: studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12198182
Kuzuyama T Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units. 2002 Biosci. Biotechnol. Biochem. pmid:12353619
Dagna L et al. Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes. 2002 Eur. J. Immunol. pmid:12355447
Brüggemann N and Schnitzler JP Relationship of isopentenyl diphosphate (IDP) isomerase activity to isoprene emission of oak leaves. 2002 Tree Physiol. pmid:12359528
pmid:12374295
Hümbelin M et al. Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens. 2002 Gene pmid:12384294
Cipriani B et al. Involvement of classical and novel protein kinase C isoforms in the response of human V gamma 9V delta 2 T cells to phosphate antigens. 2002 J. Immunol. pmid:12421956
Hirooka K et al. Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase. 2003 Biochem. J. pmid:12437513
Nagata N et al. Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway. 2002 Planta pmid:12447549
pmid:12479413
Altincicek B et al. LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis. 2002 FEBS Lett. pmid:12482608
Chen AP et al. Synthesis and application of a fluorescent substrate analogue to study ligand interactions for undecaprenyl pyrophosphate synthase. 2002 J. Am. Chem. Soc. pmid:12487597
pmid:12499403
Flores-Sánchez IJ et al. Biosynthesis of sterols and triterpenes in cell suspension cultures of Uncaria tomentosa. 2002 Plant Cell Physiol. pmid:12514247
Miyazawa Y et al. Amyloplast formation in cultured tobacco BY-2 cells requires a high cytokinin content. 2002 Plant Cell Physiol. pmid:12514251
pmid:12531482
Palazón J et al. Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. 2003 J. Biotechnol. pmid:12568744
Wang YD et al. Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei. 2003 Biotechnol. Appl. Biochem. pmid:12578550