| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Macrae S et al. | Rubber production in guayule: determination of rubber producing potential. | 1986 | Plant Physiol. | pmid:16664938 |
| Schulze-Siebert D and Schultz G | beta-Carotene Synthesis in Isolated Spinach Chloroplasts : Its Tight Linkage to Photosynthetic Carbon Metabolism. | 1987 | Plant Physiol. | pmid:16665589 |
| Madhavan S et al. | Stimulation of Isopentenyl Pyrophosphate Incorporation into Polyisoprene in Extracts from Guayule Plants (Parthenium argentatum Gray) by Low Temperature and 2-(3,4-Dichlorophenoxy) Triethylamine. | 1989 | Plant Physiol. | pmid:16666574 |
| pmid:16678341 | ||||
| Kavanagh KL et al. | The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding. | 2006 | J. Biol. Chem. | pmid:16698791 |
| Chemler JA et al. | Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. | 2006 | Microb. Cell Fact. | pmid:16719921 |
| Houde M et al. | Wheat EST resources for functional genomics of abiotic stress. | 2006 | BMC Genomics | pmid:16772040 |
| pmid:16780905 | ||||
| pmid:16790937 | ||||
| pmid:16793276 | ||||
| Zahiri HS et al. | Coenzyme Q10 production in recombinant Escherichia coli strains engineered with a heterologous decaprenyl diphosphate synthase gene and foreign mevalonate pathway. | 2006 | Metab. Eng. | pmid:16815062 |
| Hsiao YY et al. | Comparison of transcripts in Phalaenopsis bellina and Phalaenopsis equestris (Orchidaceae) flowers to deduce monoterpene biosynthesis pathway. | 2006 | BMC Plant Biol. | pmid:16836766 |
| Zahiri HS et al. | Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16896603 |
| pmid:16900467 | ||||
| Gibon Y et al. | Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes. | 2006 | Genome Biol. | pmid:16916443 |
| Forster AC and Church GM | Towards synthesis of a minimal cell. | 2006 | Mol. Syst. Biol. | pmid:16924266 |
| pmid:16939278 | ||||
| Maurice T et al. | Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection. | 2006 | Pharmacol. Biochem. Behav. | pmid:16945406 |
| pmid:16956297 | ||||
| Muñoz-Bertomeu J et al. | Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender. | 2006 | Plant Physiol. | pmid:16980564 |
| Fischbach MA and Walsh CT | Biochemistry. Directing biosynthesis. | 2006 | Science | pmid:17068249 |
| Quinzii CM et al. | Human coenzyme Q10 deficiency. | 2007 Apr-May | Neurochem. Res. | pmid:17094036 |
| Scott KM et al. | The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2. | 2006 | PLoS Biol. | pmid:17105352 |
| Yoon SH et al. | Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115209 |
| Theivagt AE et al. | Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity. | 2006 | Biochemistry | pmid:17128979 |
| Hebbeler AM et al. | Individual Vgamma2-Jgamma1.2+ T cells respond to both isopentenyl pyrophosphate and Daudi cell stimulation: generating tumor effectors with low molecular weight phosphoantigens. | 2007 | Cancer Immunol. Immunother. | pmid:17131122 |
| pmid:17137593 | ||||
| Thulasiram HV and Poulter CD | Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity. | 2006 | J. Am. Chem. Soc. | pmid:17147392 |
| Enfissi EM et al. | Metabolic engineering of the mevalonate and non-mevalonate isopentenyl diphosphate-forming pathways for the production of health-promoting isoprenoids in tomato. | 2005 | Plant Biotechnol. J. | pmid:17168896 |
| Kloer DP et al. | Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba. | 2006 | Biochemistry | pmid:17176041 |
| pmid:17178381 | ||||
| Laupitz R et al. | Stereochemical studies on the making and unmaking of isopentenyl diphosphate in different biological systems. | 2004 | Chem. Biodivers. | pmid:17191914 |
| Clizbe DB et al. | IDI2, a second isopentenyl diphosphate isomerase in mammals. | 2007 | J. Biol. Chem. | pmid:17202134 |
| pmid:17209429 | ||||
| pmid:17250851 | ||||
| pmid:17257214 | ||||
| pmid:17257708 | ||||
| Amslinger S et al. | Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate. | 2007 | Immunobiology | pmid:17270709 |
| pmid:17291279 | ||||
| Omoigui S | The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | 2007 | Immun Ageing | pmid:17374166 |
| Sgraja T et al. | Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. | 2007 | BMC Struct. Biol. | pmid:17397541 |
| Christianson DW | Chemistry. Roots of biosynthetic diversity. | 2007 | Science | pmid:17412944 |
| Rothman SC et al. | Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species. | 2007 | Biochemistry | pmid:17428035 |
| Puan KJ et al. | Preferential recognition of a microbial metabolite by human Vgamma2Vdelta2 T cells. | 2007 | Int. Immunol. | pmid:17446209 |
| Julsing MK et al. | Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17458547 |
| Glickman JF and Schmid A | Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay. | 2007 | Assay Drug Dev Technol | pmid:17477829 |
| Henriksson LM et al. | Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. | 2007 | J. Biol. Chem. | pmid:17491006 |
| Yoon SH et al. | Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. | 2007 May-Jun | Biotechnol. Prog. | pmid:17500531 |
| Schirra F et al. | Androgen influence on cholesterogenic enzyme mRNA levels in the mouse meibomian gland. | 2007 | Curr. Eye Res. | pmid:17514523 |
| Walsh CT | Revealing coupling patterns in isoprenoid alkylation biocatalysis. | 2007 | ACS Chem. Biol. | pmid:17518430 |