MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid:15650872 | ||||
pmid:28478108 | ||||
pmid:20920623 | ||||
pmid:19055484 | ||||
pmid:18843409 | ||||
pmid:17209429 | ||||
pmid:15765206 | ||||
pmid:12680756 | ||||
pmid:28342224 | ||||
pmid: | ||||
Walsh CT | Revealing coupling patterns in isoprenoid alkylation biocatalysis. | 2007 | ACS Chem. Biol. | pmid:17518430 |
Bitok JK and Meyers CF | 2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity. | 2012 | ACS Chem. Biol. | pmid:22839733 |
Dellas N and Noel JP | Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates. | 2010 | ACS Chem. Biol. | pmid:20392112 |
Mabanglo MF et al. | X-ray structures of isopentenyl phosphate kinase. | 2010 | ACS Chem. Biol. | pmid:20402538 |
Mabanglo MF et al. | Mutagenesis of isopentenyl phosphate kinase to enhance geranyl phosphate kinase activity. | 2012 | ACS Chem. Biol. | pmid:22533411 |
Kamińska J et al. | Rsp5 ubiquitin ligase affects isoprenoid pathway and cell wall organization in S. cerevisiae. | 2005 | Acta Biochim. Pol. | pmid:15827618 |
Szkopińska A and Płochocka D | Farnesyl diphosphate synthase; regulation of product specificity. | 2005 | Acta Biochim. Pol. | pmid:15827605 |
Wanke M et al. | Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway. | 2001 | Acta Biochim. Pol. | pmid:11833775 |
Björkelid C et al. | Structural and functional studies of mycobacterial IspD enzymes. | 2011 | Acta Crystallogr. D Biol. Crystallogr. | pmid:21543842 |
Ariyawutthiphan O et al. | Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation. | 2012 | Acta Crystallogr. D Biol. Crystallogr. | pmid:23090405 |