Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

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Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Wang YD et al. Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei. 2007 Cell Biol. Int. pmid:17521928
Na-Bangchang K et al. Pharmacokinetics and pharmacodynamics of fosmidomycin monotherapy and combination therapy with clindamycin in the treatment of multidrug resistant falciparum malaria. 2007 Malar. J. pmid:17531088
Huang J and Gogarten JP Did an ancient chlamydial endosymbiosis facilitate the establishment of primary plastids? 2007 Genome Biol. pmid:17547748
Kulaber A et al. Pro-inflammatory cellular immune response in Behçet's disease. 2007 Rheumatol. Int. pmid:17549482
Cassera MB et al. Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum. 2007 Mem. Inst. Oswaldo Cruz pmid:17568945
Lopes AA et al. Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). 2007 Phytochemistry pmid:17574633
Poulter CD and Rilling HC Prenyltransferase: the mechanism of the reaction. 1976 Biochemistry pmid:175829
Byres E et al. Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity. 2007 J. Mol. Biol. pmid:17583736
Grimplet J et al. Tissue-specific mRNA expression profiling in grape berry tissues. 2007 BMC Genomics pmid:17584945
Nagaki M et al. Substrate specificities of wild and mutated farnesyl diphosphate synthases from Bacillus stearothermophilus with artificial substrates. 2007 Biosci. Biotechnol. Biochem. pmid:17617711
Bock O et al. Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. 2007 Apr-Jun J Musculoskelet Neuronal Interact pmid:17627083
pmid:17628182
Kinjoh T et al. Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata. 2007 Insect Biochem. Mol. Biol. pmid:17628279
Saito K et al. Short-chain prenyl diphosphate synthase that condenses isopentenyl diphosphate with dimethylallyl diphosphate in ispA null Escherichia coli strain lacking farnesyl diphosphate synthase. 2007 J. Biosci. Bioeng. pmid:17630132
pmid:17634747
pmid:17634749
Ericsson J et al. Characterization and distribution of cis-prenyl transferase participating in liver microsomal polyisoprenoid biosynthesis. 1991 Eur. J. Biochem. pmid:1765092
Murphy DJ and Brown JR Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. 2007 BMC Infect. Dis. pmid:17655757
Lodato P et al. Expression of the carotenoid biosynthesis genes in Xanthophyllomyces dendrorhous. 2007 Biol. Res. pmid:17657357
Schmidt A and Gershenzon J Cloning and characterization of two different types of geranyl diphosphate synthases from Norway spruce (Picea abies). 2008 Phytochemistry pmid:17673268
Klein-Marcuschamer D et al. Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene. 2007 Trends Biotechnol. pmid:17681626
Sangar V et al. Quantitative sequence-function relationships in proteins based on gene ontology. 2007 BMC Bioinformatics pmid:17686158
Withers ST et al. Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. 2007 Appl. Environ. Microbiol. pmid:17693564
Towler MJ and Weathers PJ Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. 2007 Plant Cell Rep. pmid:17710406
Anisimova M et al. Phylogenomic analysis of natural selection pressure in Streptococcus genomes. 2007 BMC Evol. Biol. pmid:17760998
pmid:17763867
Matsumura Y et al. The carboxyl-terminal region of the geranylgeranyl diphosphate synthase is indispensable for the stabilization of the region involved in substrate binding and catalysis. 2007 J. Biochem. pmid:17846065
Mönkkönen H et al. Zoledronic acid-induced IPP/ApppI production in vivo. 2007 Life Sci. pmid:17850825
pmid:17899066
Das A et al. An update on microbial carotenoid production: application of recent metabolic engineering tools. 2007 Appl. Microbiol. Biotechnol. pmid:17912511
Arimura G et al. Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling. 2008 Planta pmid:17924138
Hoshino T and Eguchi T Functional analysis of type 1 isopentenyl diphosphate isomerase from Halobacterium sp. NRC-1. 2007 Biosci. Biotechnol. Biochem. pmid:17928693
Buetow L et al. The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery. 2007 BMC Struct. Biol. pmid:17956607
Jassbi AR et al. Silencing geranylgeranyl diphosphate synthase in Nicotiana attenuata dramatically impairs resistance to tobacco hornworm. 2008 Plant Physiol. pmid:17965175
Fujiwara S et al. Efficient synthesis of trans-polyisoprene compounds using two thermostable enzymes in an organic-aqueous dual-liquid phase system. 2008 Biochem. Biophys. Res. Commun. pmid:17976371
Moe M et al. Gene expression profiles in testis of pigs with extreme high and low levels of androstenone. 2007 BMC Genomics pmid:17988377
Soundararajan R et al. Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis. 2008 J. Biol. Chem. pmid:18032389
Mi J et al. Age-related subproteomic analysis of mouse liver and kidney peroxisomes. 2007 Proteome Sci pmid:18042274
Touzé T et al. Periplasmic phosphorylation of lipid A is linked to the synthesis of undecaprenyl phosphate. 2008 Mol. Microbiol. pmid:18047581
Wilcox CB et al. Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer. 2007 BMC Cancer pmid:18070364
pmid:18076031
pmid:18088143
Velasco R et al. A high quality draft consensus sequence of the genome of a heterozygous grapevine variety. 2007 PLoS ONE pmid:18094749
pmid:18221182
Reed BC and Rilling HC Substrate Binding of avian liver prenyltransferase. 1976 Biochemistry pmid:182217
Thibodeaux CJ et al. Evidence for the involvement of acid/base chemistry in the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus aureus. 2008 Biochemistry pmid:18229948
Moreno SN and Li ZH Anti-infectives targeting the isoprenoid pathway of Toxoplasma gondii. 2008 Expert Opin. Ther. Targets pmid:18269336
Falb M et al. Metabolism of halophilic archaea. 2008 Extremophiles pmid:18278431
Gold MC et al. Human innate Mycobacterium tuberculosis-reactive alphabetaTCR+ thymocytes. 2008 PLoS Pathog. pmid:18282101
Vaccarelli G et al. Genomic organization and recombinational unit duplication-driven evolution of ovine and bovine T cell receptor gamma loci. 2008 BMC Genomics pmid:18282289