| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Brodelius M et al. | Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum. | 2002 | Eur. J. Biochem. | pmid:12135497 |
| Glatzel A et al. | Patterns of chemokine receptor expression on peripheral blood gamma delta T lymphocytes: strong expression of CCR5 is a selective feature of V delta 2/V gamma 9 gamma delta T cells. | 2002 | J. Immunol. | pmid:11994442 |
| Gougeon ML et al. | Innate T cell immunity to HIV-infection. Immunotherapy with phosphocarbohydrates, a novel strategy of immune intervention? | 2002 | Vaccine | pmid:11983250 |
| Chen AP et al. | Synthesis and application of a fluorescent substrate analogue to study ligand interactions for undecaprenyl pyrophosphate synthase. | 2002 | J. Am. Chem. Soc. | pmid:12487597 |
| Yang D et al. | Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily. | 2002 | J. Biol. Chem. | pmid:11751891 |
| Chen YH et al. | Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutants. | 2002 | J. Biol. Chem. | pmid:11744728 |
| Feurle J et al. | Escherichia coli produces phosphoantigens activating human gamma delta T cells. | 2002 | J. Biol. Chem. | pmid:11675382 |
| Wang H et al. | Conservation of nonpeptide antigen recognition by rhesus monkey V gamma 2V delta 2 T cells. | 2003 | J. Immunol. | pmid:12646635 |
| Laule O et al. | Crosstalk between cytosolic and plastidial pathways of isoprenoid biosynthesis in Arabidopsis thaliana. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12748386 |
| Bieback K et al. | Expansion of human gamma/delta T cells in vitro is differentially regulated by the measles virus glycoproteins. | 2003 | J. Gen. Virol. | pmid:12692283 |
| Reichenberg A et al. | Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human gammadelta T cells but does not lead to competitive antagonism. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12657258 |
| Wolff M et al. | Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. | 2003 | FEBS Lett. | pmid:12706830 |
| Kuzuyama T and Seto H | Diversity of the biosynthesis of the isoprene units. | 2003 | Nat Prod Rep | pmid:12735695 |
| Wang YD et al. | Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei. | 2003 | Biotechnol. Appl. Biochem. | pmid:12578550 |
| Biswas P et al. | Double-edged effect of Vgamma9/Vdelta2 T lymphocytes on viral expression in an in vitro model of HIV-1/mycobacteria co-infection. | 2003 | Eur. J. Immunol. | pmid:12594854 |
| Souret FF et al. | Scale-up of Artemisia annua L. hairy root cultures produces complex patterns of terpenoid gene expression. | 2003 | Biotechnol. Bioeng. | pmid:12889030 |
| Gallagher CE et al. | Surrogate biochemistry: use of Escherichia coli to identify plant cDNAs that impact metabolic engineering of carotenoid accumulation. | 2003 | Appl. Microbiol. Biotechnol. | pmid:12664151 |
| Palazón J et al. | Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. | 2003 | J. Biotechnol. | pmid:12568744 |
| Kharel Y et al. | Significance of highly conserved aromatic residues in Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase. | 2003 | J. Biochem. | pmid:14769870 |
| Zenitani S et al. | Gerfelin, a novel inhibitor of geranylgeranyl diphosphate synthase from Beauveria felina QN22047. I. Taxonomy, fermentation, isolation, and biological activities. | 2003 | J. Antibiot. | pmid:14513904 |
| Kawasaki T et al. | Interconversion of the product specificity of type I eubacterial farnesyl diphosphate synthase and geranylgeranyl diphosphate synthase through one amino acid substitution. | 2003 | J. Biochem. | pmid:12761202 |
| Hirooka K et al. | Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase. | 2003 | Biochem. J. | pmid:12437513 |
| Chang SY et al. | Identification of the active conformation and the importance of length of the flexible loop 72-83 in regulating the conformational change of undecaprenyl pyrophosphate synthase. | 2003 | Biochemistry | pmid:14661956 |
| Hogenboom S et al. | Cholesterol biosynthesis is not defective in peroxisome biogenesis defective fibroblasts. | 2003 | Mol. Genet. Metab. | pmid:14680974 |
| Bick JA and Lange BM | Metabolic cross talk between cytosolic and plastidial pathways of isoprenoid biosynthesis: unidirectional transport of intermediates across the chloroplast envelope membrane. | 2003 | Arch. Biochem. Biophys. | pmid:12831836 |
| Hemmerlin A et al. | Enzymes encoded by the farnesyl diphosphate synthase gene family in the Big Sagebrush Artemisia tridentata ssp. spiciformis. | 2003 | J. Biol. Chem. | pmid:12782626 |
| Carter OA et al. | Monoterpene biosynthesis pathway construction in Escherichia coli. | 2003 | Phytochemistry | pmid:12943759 |
| Triolo G et al. | Vgamma9/Vdelta2 T lymphocytes in Italian patients with Behçet's disease: evidence for expansion, and tumour necrosis factor receptor II and interleukin-12 receptor beta1 expression in active disease. | 2003 | Arthritis Res. Ther. | pmid:12932289 |
| Mau CJ et al. | Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase. | 2003 | Eur. J. Biochem. | pmid:14511375 |
| Kawasaki T et al. | A relationship between the mevalonate pathway and isoprenoid production in actinomycetes. | 2003 | J. Antibiot. | pmid:14763562 |
| Hemmerlin A et al. | Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells. | 2003 | J. Biol. Chem. | pmid:12736259 |
| Neundorf I et al. | Evidence for the combined participation of a C10 and a C15 precursor in the biosynthesis of moenocinol, the lipid part of the moenomycin antibiotics. | 2003 | Chembiochem | pmid:14613112 |
| Hong SB et al. | Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots. | 2003 May-Jun | Biotechnol. Prog. | pmid:12790690 |
| Chau M and Croteau R | Molecular cloning and characterization of a cytochrome P450 taxoid 2alpha-hydroxylase involved in Taxol biosynthesis. | 2004 | Arch. Biochem. Biophys. | pmid:15178487 |
| Sutherlin A and Rodwell VW | Multienzyme mevalonate pathway bioreactor. | 2004 | Biotechnol. Bioeng. | pmid:15286992 |
| Verjans GM et al. | Isopentenyl pyrophosphate-reactive Vgamma9Vdelta 2 T helper 1-like cells are the major gammadelta T cell subset recovered from lesions of patients with genital herpes. | 2004 | J. Infect. Dis. | pmid:15243921 |
| Ralph SA et al. | Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. | 2004 | Nat. Rev. Microbiol. | pmid:15083156 |
| Dhiman RK et al. | Identification of a novel class of omega,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis. | 2004 | J. Lipid Res. | pmid:15060088 |
| Kalyan S and Chow AW | Human peripheral gammadelta T cells potentiate the early proinflammatory cytokine response to staphylococcal toxic shock syndrome toxin-1. | 2004 | J. Infect. Dis. | pmid:15122526 |
| Workalemahu G et al. | Expression and synthesis of fibroblast growth factor-9 in human gammadelta T-lymphocytes. Response to isopentenyl pyrophosphate and TGF-beta1/IL-15. | 2004 | J. Leukoc. Biol. | pmid:14704367 |
| Scholte AA et al. | Synthesis and biological activity of isopentenyl diphosphate analogues. | 2004 | Bioorg. Med. Chem. | pmid:14759736 |
| Cassera MB et al. | The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum. | 2004 | J. Biol. Chem. | pmid:15452112 |
| Boylston WH et al. | Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice. | 2004 | Aging Cell | pmid:15379852 |
| Forsea AM et al. | Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells. | 2004 | Br. J. Cancer | pmid:15280922 |
| Kunzmann V et al. | Polyinosinic-polycytidylic acid-mediated stimulation of human gammadelta T cells via CD11c dendritic cell-derived type I interferons. | 2004 | Immunology | pmid:15196204 |
| Glazko GV and Mushegian AR | Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patterns. | 2004 | Genome Biol. | pmid:15128446 |
| Raschke M et al. | A high-performance liquid chromatography method for the analysis of intermediates of the deoxyxylulose phosphate pathway. | 2004 | Anal. Biochem. | pmid:15556562 |
| Botella-PavÃa P et al. | Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors. | 2004 | Plant J. | pmid:15447646 |
| Laupitz R et al. | Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. | 2004 | Eur. J. Biochem. | pmid:15206931 |
| Rohdich F et al. | Perspectives in anti-infective drug design. The late steps in the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate. | 2004 | Bioorg. Chem. | pmid:15381396 |