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Mol. Microbiol. |
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Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. |
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Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. |
2008 |
BMC Biotechnol. |
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Dynamical modeling of the cholesterol regulatory pathway with Boolean networks. |
2008 |
BMC Syst Biol |
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Fujiwara S et al. |
Efficient synthesis of trans-polyisoprene compounds using two thermostable enzymes in an organic-aqueous dual-liquid phase system. |
2008 |
Biochem. Biophys. Res. Commun. |
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Assessment of the pharmacokinetics and dynamics of two combination regimens of fosmidomycin-clindamycin in patients with acute uncomplicated falciparum malaria. |
2008 |
Malar. J. |
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NF-kappa B modulates sensitivity to apoptosis, proinflammatory and migratory potential in short- versus long-term cultured human gamma delta lymphocytes. |
2008 |
J. Immunol. |
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Immunity, ageing and cancer. |
2008 |
Immun Ageing |
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Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis. |
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J. Biol. Chem. |
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Optimizing dosing frequencies for bisphosphonates in the management of postmenopausal osteoporosis: patient considerations. |
2008 |
Clin Interv Aging |
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Boëdec A et al. |
Synthesis and biological activity of phosphonate analogues and geometric isomers of the highly potent phosphoantigen (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate. |
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J. Med. Chem. |
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Monoclinic form of isopentenyl diphosphate isomerase: a case of polymorphism in biomolecular crystals. |
2008 |
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. |
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Argout X et al. |
Towards the understanding of the cocoa transcriptome: Production and analysis of an exhaustive dataset of ESTs of Theobroma cacao L. generated from various tissues and under various conditions. |
2008 |
BMC Genomics |
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Jassbi AR et al. |
Silencing geranylgeranyl diphosphate synthase in Nicotiana attenuata dramatically impairs resistance to tobacco hornworm. |
2008 |
Plant Physiol. |
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Schmidt A and Gershenzon J |
Cloning and characterization of two different types of geranyl diphosphate synthases from Norway spruce (Picea abies). |
2008 |
Phytochemistry |
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AlcaÃno J et al. |
Cloning of the cytochrome p450 reductase (crtR) gene and its involvement in the astaxanthin biosynthesis of Xanthophyllomyces dendrorhous. |
2008 |
BMC Microbiol. |
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Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth. |
2008 |
Anticancer Drugs |
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Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. |
2007 May-Jun |
Biotechnol. Prog. |
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Human coenzyme Q10 deficiency. |
2007 Apr-May |
Neurochem. Res. |
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Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. |
2007 Apr-Jun |
J Musculoskelet Neuronal Interact |
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Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. |
2007 |
Appl. Microbiol. Biotechnol. |
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An update on microbial carotenoid production: application of recent metabolic engineering tools. |
2007 |
Appl. Microbiol. Biotechnol. |
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2007 |
ACS Chem. Biol. |
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Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate. |
2007 |
Immunobiology |
pmid:17270709
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Chemistry. Roots of biosynthetic diversity. |
2007 |
Science |
pmid:17412944
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Omoigui S |
The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. |
2007 |
Immun Ageing |
pmid:17374166
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Substrate specificities of wild and mutated farnesyl diphosphate synthases from Bacillus stearothermophilus with artificial substrates. |
2007 |
Biosci. Biotechnol. Biochem. |
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Phylogenomic analysis of natural selection pressure in Streptococcus genomes. |
2007 |
BMC Evol. Biol. |
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Sangar V et al. |
Quantitative sequence-function relationships in proteins based on gene ontology. |
2007 |
BMC Bioinformatics |
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Expression of the carotenoid biosynthesis genes in Xanthophyllomyces dendrorhous. |
2007 |
Biol. Res. |
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Huang J and Gogarten JP |
Did an ancient chlamydial endosymbiosis facilitate the establishment of primary plastids? |
2007 |
Genome Biol. |
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Murphy DJ and Brown JR |
Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. |
2007 |
BMC Infect. Dis. |
pmid:17655757
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Na-Bangchang K et al. |
Pharmacokinetics and pharmacodynamics of fosmidomycin monotherapy and combination therapy with clindamycin in the treatment of multidrug resistant falciparum malaria. |
2007 |
Malar. J. |
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IDI2, a second isopentenyl diphosphate isomerase in mammals. |
2007 |
J. Biol. Chem. |
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New insights into the genetic regulation of Plasmodium falciparum obtained by Bayesian modeling. |
2007 |
Gene Regul Syst Bio |
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Lopes AA et al. |
Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). |
2007 |
Phytochemistry |
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Kulaber A et al. |
Pro-inflammatory cellular immune response in Behçet's disease. |
2007 |
Rheumatol. Int. |
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Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. |
2007 |
BMC Struct. Biol. |
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Wang YD et al. |
Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei. |
2007 |
Cell Biol. Int. |
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Preferential recognition of a microbial metabolite by human Vgamma2Vdelta2 T cells. |
2007 |
Int. Immunol. |
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Henriksson LM et al. |
Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. |
2007 |
J. Biol. Chem. |
pmid:17491006
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Rothman SC et al. |
Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species. |
2007 |
Biochemistry |
pmid:17428035
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Julsing MK et al. |
Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. |
2007 |
Appl. Microbiol. Biotechnol. |
pmid:17458547
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Glickman JF and Schmid A |
Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay. |
2007 |
Assay Drug Dev Technol |
pmid:17477829
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Saito K et al. |
Short-chain prenyl diphosphate synthase that condenses isopentenyl diphosphate with dimethylallyl diphosphate in ispA null Escherichia coli strain lacking farnesyl diphosphate synthase. |
2007 |
J. Biosci. Bioeng. |
pmid:17630132
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Grimplet J et al. |
Tissue-specific mRNA expression profiling in grape berry tissues. |
2007 |
BMC Genomics |
pmid:17584945
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Cassera MB et al. |
Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum. |
2007 |
Mem. Inst. Oswaldo Cruz |
pmid:17568945
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Schirra F et al. |
Androgen influence on cholesterogenic enzyme mRNA levels in the mouse meibomian gland. |
2007 |
Curr. Eye Res. |
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Hebbeler AM et al. |
Individual Vgamma2-Jgamma1.2+ T cells respond to both isopentenyl pyrophosphate and Daudi cell stimulation: generating tumor effectors with low molecular weight phosphoantigens. |
2007 |
Cancer Immunol. Immunother. |
pmid:17131122
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Byres E et al. |
Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity. |
2007 |
J. Mol. Biol. |
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