MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wang H et al. | Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human Vγ2Vδ2 T cells. | 2013 | J. Immunol. | pmid:23833237 |
Vavassori S et al. | Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. | 2013 | Nat. Immunol. | pmid:23872678 |
Ueno A et al. | Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis. | 2013 | Parasitol. Int. | pmid:23276703 |
Tong H et al. | Quantitative determination of isopentenyl diphosphate in cultured mammalian cells. | 2013 | Anal. Biochem. | pmid:23000003 |
Liu YL et al. | Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24927548 |
Ebert R et al. | Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells. | 2014 | Mol. Cancer | pmid:25496233 |
Laurent AJ et al. | Synergistic effects of ethanol and isopentenyl pyrophosphate on expansion of γδ T cells in synovial fluid from patients with arthritis. | 2014 | PLoS ONE | pmid:25090614 |
Krasutsky SG et al. | Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens. | 2014 | J. Org. Chem. | pmid:25184438 |
Heider SA et al. | IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum. | 2014 | FEBS J. | pmid:25181035 |
Teufel R et al. | One-pot enzymatic synthesis of merochlorin A and B. | 2014 | Angew. Chem. Int. Ed. Engl. | pmid:25115835 |