Geranyl diphosphate

Geranyl diphosphate is a lipid of Prenol Lipids (PR) class. The involved functions are known as Prenylation, Anabolism, Biochemical Pathway and Methylation. Geranyl diphosphate often locates in Membrane and Plastids. The associated genes with Geranyl diphosphate are GGPS1 gene, NKS1 gene, COQ2 gene and MIB1 gene.

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Introduction

To understand associated biological information of Geranyl diphosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Geranyl diphosphate?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Geranyl diphosphate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Geranyl diphosphate?

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What functions are associated with Geranyl diphosphate?


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What lipids are associated with Geranyl diphosphate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Geranyl diphosphate?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Geranyl diphosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Geranyl diphosphate

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Authors Title Published Journal PubMed Link
Savage TJ et al. Condensation of the isoprenoid and amino precursors in the biosynthesis of domoic acid. 2012 Toxicon pmid:22041653
Mann FM et al. Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. 2011 FEBS Lett. pmid:21237161
Nakano C et al. Identification of the first bacterial monoterpene cyclase, a 1,8-cineole synthase, that catalyzes the direct conversion of geranyl diphosphate. 2011 Chembiochem pmid:21726035
Schmidt A et al. Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). 2011 Plant Mol. Biol. pmid:22002747
Tsuji F et al. The geranyl-modified tryptophan residue is crucial for ComXRO-E-2 pheromone biological activity. 2011 Bioorg. Med. Chem. Lett. pmid:21636272
Nagegowda DA The small subunit of geranyl diphosphate synthase: a tool to improve aroma and flavour by metabolic engineering. 2010 J. Biosci. pmid:20689171
Hong YJ and Tantillo DJ Quantum chemical dissection of the classic terpinyl/pinyl/bornyl/camphyl cation conundrum-the role of pyrophosphate in manipulating pathways to monoterpenes. 2010 Org. Biomol. Chem. pmid:20725661
Schilmiller AL et al. Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19487664
Gilg AB et al. Unique animal prenyltransferase with monoterpene synthase activity. 2009 Naturwissenschaften pmid:19277597
Navia-Giné WG et al. Medicago truncatula (E)-beta-ocimene synthase is induced by insect herbivory with corresponding increases in emission of volatile ocimene. 2009 Plant Physiol. Biochem. pmid:19249223
Vandermoten S et al. Structural features conferring dual geranyl/farnesyl diphosphate synthase activity to an aphid prenyltransferase. 2009 Insect Biochem. Mol. Biol. pmid:19720147
Xiao Y et al. Prenyltransferase substrate binding pocket flexibility and its application in isoprenoid profiling. 2009 Mol Biosyst pmid:19668852
Holstein SA et al. Quantitative determination of geranyl diphosphate levels in cultured human cells. 2009 Lipids pmid:19856009
Orlova I et al. The small subunit of snapdragon geranyl diphosphate synthase modifies the chain length specificity of tobacco geranylgeranyl diphosphate synthase in planta. 2009 Plant Cell pmid:20028839
Sillero MA et al. Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. 2009 Biochem. Pharmacol. pmid:19414000
Komatsu M et al. Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18492804
Davidovich-Rikanati R et al. Overexpression of the lemon basil alpha-zingiberene synthase gene increases both mono- and sesquiterpene contents in tomato fruit. 2008 Plant J. pmid:18643974
Schmidt A and Gershenzon J Cloning and characterization of two different types of geranyl diphosphate synthases from Norway spruce (Picea abies). 2008 Phytochemistry pmid:17673268
Matsumura Y et al. The carboxyl-terminal region of the geranylgeranyl diphosphate synthase is indispensable for the stabilization of the region involved in substrate binding and catalysis. 2007 J. Biochem. pmid:17846065
Kremer A et al. A 7-dimethylallyltryptophan synthase from Aspergillus fumigatus: overproduction, purification and biochemical characterization. 2007 Microbiology (Reading, Engl.) pmid:17906140