| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gastrointestinal Hemorrhage | D006471 | 27 associated lipids |
Total
1
Geranial
Geranial is a lipid of Prenol Lipids (PR) class. Geranial is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Oxidation, Process, geranial dehydrogenase activity and retinoid X receptor binding. Geranial often locates in soluble. The associated genes with Geranial are CDKN1A gene.
Cross Reference
Introduction
To understand associated biological information of Geranial, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Geranial?
Geranial is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Geranial
PubChem Associated disorders and diseases
What pathways are associated with Geranial
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Geranial?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Geranial?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Geranial?
There are no associated biomedical information in the current reference collection.
What genes are associated with Geranial?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Geranial?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Geranial
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang CY | [The active principles of Litsea cubeba in the treatment of coronary heart disease]. | 1985 | Zhong Yao Tong Bao | pmid:2935312 |
| Zhou J | [Progress of Litsea cubeba emulsion in the pharmacological and therapeutic research]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1954669 |
| Zhou Y | [Antifungal activity of volatile oils in Litsea cubeba and its main constituent citral]. | 1984 | Zhong Xi Yi Jie He Za Zhi | pmid:6240351 |
| Saeidnia S et al. | Bioactive compounds of the volatile oil of Dracocephalum kotschyi. | 2007 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:18274279 |
| Li H et al. | [Allelopathic effects of Cymbopogon citratu volatile and its chemical components]. | 2005 | Ying Yong Sheng Tai Xue Bao | pmid:16011184 |
| Fujita S | [Miscellaneous contributions to the essential oils of plants from various territories. XLVII. On the components of essential oils of Cinnamomum sieboldii Meisn]. | 1986 | Yakugaku Zasshi | pmid:3701596 |
| Ishida T et al. | Terpenoid biotransformation in mammals. V. Metabolism of (+)-citronellal, (+-)-7-hydroxycitronellal, citral, (-)-perillaldehyde, (-)-myrtenal, cuminaldehyde, thujone, and (+-)-carvone in rabbits. | 1989 | Xenobiotica | pmid:2815827 |
| Luo M et al. | [Preliminary study on citral impaires the Aspergillus flavus membrane]. | 2001 | Wei Sheng Wu Xue Bao | pmid:12552830 |
| Luo M et al. | [Study on quantitative test on the DNA damage of Aspergillus flavus caused by citral with a comet analysis system]. | 2002 | Wei Sheng Wu Xue Bao | pmid:12557377 |
| Luo M and Jiang L | [Study on biochemical mechanism of citral damage to the A. flavasi's mitochondria]. | 2002 | Wei Sheng Wu Xue Bao | pmid:12557401 |
| Luo M et al. | [Mitochondria aberration of Aspergillus flavus under citral stress circumstance]. | 2006 | Wei Sheng Wu Xue Bao | pmid:17302172 |
| Luo M et al. | [Study on morphological change of aspergillus flavus damaged by citral with a multi-channel micro-spectrophotometer system]. | 2003 | Wei Sheng Wu Xue Bao | pmid:16279209 |
| Geldof AA et al. | Estrogenic action of commonly used fragrant agent citral induces prostatic hyperplasia. | 1992 | Urol. Res. | pmid:1372772 |
| Papadoukakis S et al. | Quantitative study of mast cells in experimentally induced benign prostatic hyperplasia. | 2010 | Urol. Int. | pmid:20173378 |
| Mikkola JP et al. | Utilisation of on-line acoustic irradiation as a means to counter-effect catalyst deactivation in heterogeneous catalysis. | 2004 | Ultrason Sonochem | pmid:15081987 |
| Nogueira AC et al. | Study on the embryofeto-toxicity of citral in the rat. | 1995 | Toxicology | pmid:7886681 |
| Ress NB et al. | Toxicology and carcinogenesis studies of microencapsulated citral in rats and mice. | 2003 | Toxicol. Sci. | pmid:12563105 |
| Takahashi T et al. | An in vitro test to screen skin sensitizers using a stable THP-1-derived IL-8 reporter cell line, THP-G8. | 2011 | Toxicol. Sci. | pmid:21920952 |
| Jung KM et al. | B cell increases and ex vivo IL-2 production as secondary endpoints for the detection of sensitizers in non-radioisotopic local lymph node assay using flow cytometry. | 2012 | Toxicol. Lett. | pmid:22245253 |
| Son D et al. | Differentiation of skin sensitizers from irritant chemicals by interleukin-1α and macrophage inflammatory protein-2 in murine keratinocytes. | 2013 | Toxicol. Lett. | pmid:23178550 |
| Takeyoshi M et al. | Development of non-radio isotopic endpoint of murine local lymph node assay based on 5-bromo-2'-deoxyuridine (BrdU) incorporation. | 2001 | Toxicol. Lett. | pmid:11246173 |
| De-Oliveira AC et al. | In vitro inhibition of CYP2B1 monooxygenase by beta-myrcene and other monoterpenoid compounds. | 1997 | Toxicol. Lett. | pmid:9242356 |
| Hagvall L et al. | Cytochrome P450-mediated activation of the fragrance compound geraniol forms potent contact allergens. | 2008 | Toxicol. Appl. Pharmacol. | pmid:18824010 |
| Saito K et al. | An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. | 2017 | Toxicol In Vitro | pmid:27965148 |
| Andreas N et al. | The intra- and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: results of a ring-study in five laboratories. | 2011 | Toxicol In Vitro | pmid:21195160 |
| Mitjans M et al. | Use of IL-8 release and p38 MAPK activation in THP-1 cells to identify allergens and to assess their potency in vitro. | 2010 | Toxicol In Vitro | pmid:20541004 |
| Andres E et al. | The sensitivity of the KeratinoSensâ„¢ assay to evaluate plant extracts: a pilot study. | 2013 | Toxicol In Vitro | pmid:23428960 |
| OSATO S et al. | Experiments on the chemotherapeutic treatment of carcinoma with citral and citronellal and those combined with PCMB. | 1961 | Tohoku J. Exp. Med. | pmid:14482444 |
| KANNO J | Pharmacological studies of citral and some other aldehydes. | 1950 | Tohoku J. Exp. Med. | pmid:14809736 |
| Griffith M and Zile MH | Retinoic acid, midkine, and defects of secondary neurulation. | 2000 | Teratology | pmid:10931510 |
| Engberg N et al. | Retinoic acid synthesis promotes development of neural progenitors from mouse embryonic stem cells by suppressing endogenous, Wnt-dependent nodal signaling. | 2010 | Stem Cells | pmid:20665854 |
| Rajput SB and Karuppayil SM | Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans. | 2013 | Springerplus | pmid:23449869 |
| KAMINSKAIA ZA | [Application of citral in glaucoma]. | 1949 | Sov Med | pmid:18142086 |
| Myhre AM et al. | Retinoylation of proteins in rat hepatocytes following uptake of chylomicron remnant retinyl ester. | 1999 | Scand. J. Clin. Lab. Invest. | pmid:10533843 |
| Macedo IT et al. | Anthelmintic activity of Cymbopogon citratus against Haemonchus contortus. | 2015 Jul-Sep | Rev Bras Parasitol Vet | pmid:26444058 |
| Aiemsaard J et al. | The effect of lemongrass oil and its major components on clinical isolate mastitis pathogens and their mechanisms of action on Staphylococcus aureus DMST 4745. | 2011 | Res. Vet. Sci. | pmid:21316719 |
| Di Renzo F et al. | Citral, an inhibitor of retinoic acid synthesis, attenuates the frequency and severity of branchial arch abnormalities induced by triazole-derivative fluconazole in rat embryos cultured in vitro. | 2007 Nov-Dec | Reprod. Toxicol. | pmid:17875381 |
| Lalko J and Api AM | Citral: identifying a threshold for induction of dermal sensitization. | 2008 | Regul. Toxicol. Pharmacol. | pmid:18353514 |
| Api AM and Vey M | Implementation of the dermal sensitization Quantitative Risk Assessment (QRA) for fragrance ingredients. | 2008 | Regul. Toxicol. Pharmacol. | pmid:18635300 |
| Pause BM et al. | The nature of the late positive complex within the olfactory event-related potential (OERP). | 1996 | Psychophysiology | pmid:8753937 |
| Idrees M et al. | Alleviation of salt stress in lemongrass by salicylic acid. | 2012 | Protoplasma | pmid:21882051 |
| Scolnik M et al. | Immediate vasoactive effect of citral on the adolescent rat ventral prostate. | 1994 | Prostate | pmid:8022706 |
| Abramovici A et al. | Experimental induction of atypical hyperplasia in rat ventral prostate. | 1987 | Prog. Clin. Biol. Res. | pmid:2443923 |
| Seman-Kamarulzaman AF et al. | Novel NAD+-Farnesal Dehydrogenase from Polygonum minus Leaves. Purification and Characterization of Enzyme in Juvenile Hormone III Biosynthetic Pathway in Plant. | 2016 | PLoS ONE | pmid:27560927 |
| Shi C et al. | Antimicrobial Activity and Possible Mechanism of Action of Citral against Cronobacter sakazakii. | 2016 | PLoS ONE | pmid:27415761 |
| Stotz SC et al. | Citral sensing by Transient [corrected] receptor potential channels in dorsal root ganglion neurons. | 2008 | PLoS ONE | pmid:18461159 |
| Silva-Angulo AB et al. | Comparative study of the effects of citral on the growth and injury of Listeria innocua and Listeria monocytogenes cells. | 2015 | PLoS ONE | pmid:25643164 |
| Carraher C et al. | Sequence comparisons of odorant receptors among tortricid moths reveal different rates of molecular evolution among family members. | 2012 | PLoS ONE | pmid:22701634 |
| Yang SM et al. | Citral is renoprotective for focal segmental glomerulosclerosis by inhibiting oxidative stress and apoptosis and activating Nrf2 pathway in mice. | 2013 | PLoS ONE | pmid:24069362 |
| Dudai N et al. | Citral is a new inducer of caspase-3 in tumor cell lines. | 2005 | Planta Med. | pmid:15931590 |
| Buddhakala N et al. | Inhibitory effects of ginger oil on spontaneous and PGF2alpha-induced contraction of rat myometrium. | 2008 | Planta Med. | pmid:18484528 |
| Chaimovitsh D et al. | Microtubules are an intracellular target of the plant terpene citral. | 2010 | Plant J. | pmid:19891702 |
| Chaimovitsh D et al. | The relative effect of citral on mitotic microtubules in wheat roots and BY2 cells. | 2012 | Plant Biol (Stuttg) | pmid:22039835 |
| Paret ML et al. | Characterization of biofumigated Ralstonia solanacearum cells using micro-Raman spectroscopy and electron microscopy. | 2012 | Phytopathology | pmid:21899389 |
| do Vale TG et al. | Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) n.e. Brown. | 2002 | Phytomedicine | pmid:12587690 |
| Zore GB et al. | Terpenoids inhibit Candida albicans growth by affecting membrane integrity and arrest of cell cycle. | 2011 | Phytomedicine | pmid:21596542 |
| Ortiz MI et al. | Synergistic effect of the interaction between naproxen and citral on inflammation in rats. | 2010 | Phytomedicine | pmid:20637575 |
| Khan MS and Ahmad I | In vitro antifungal, anti-elastase and anti-keratinase activity of essential oils of Cinnamomum-, Syzygium- and Cymbopogon-species against Aspergillus fumigatus and Trichophyton rubrum. | 2011 | Phytomedicine | pmid:21893402 |
| Hierro I et al. | In vivo larvicidal activity of monoterpenic derivatives from aromatic plants against L3 larvae of Anisakis simplex s.l. | 2006 | Phytomedicine | pmid:16785045 |
| Conde R et al. | Chemical composition and therapeutic effects of Lippia alba (Mill.) N. E. Brown leaves hydro-alcoholic extract in patients with migraine. | 2011 | Phytomedicine | pmid:21802924 |
| Demyttenaere JC et al. | Biotransformation of geraniol, nerol and citral by sporulated surface cultures of Aspergillus niger and Penicillium sp. | 2000 | Phytochemistry | pmid:11117886 |
| Cerf-Ducastel B and Murphy C | Validation of a stimulation protocol suited to the investigation of odor-taste interactions with fMRI. | 2004 | Physiol. Behav. | pmid:15135010 |
| Marks LE et al. | Flavor-intensity perception: effects of stimulus context. | 2012 | Physiol. Behav. | pmid:21930139 |
| Blass EM and Pedersen PE | Surgical manipulation of the uterine environment of rat fetuses. | 1980 | Physiol. Behav. | pmid:7220640 |
| Cattarelli M and Vigouroux M | [Evaluation of emotional reactions of the rat elicited by biologicaly meaningful odorants during an operant behavior (author's transl)]. | 1981 | Physiol. Behav. | pmid:7335785 |
| Moore CL et al. | Early olfactory experience, novelty, and choice of sexual partner by male rats. | 1996 | Physiol. Behav. | pmid:8916195 |
| Asthana A et al. | Mechanisms of citral phototoxicity. | 1992 | Photochem. Photobiol. | pmid:1502265 |
| Yang Z et al. | Biphasic effect of citral, a flavoring and scenting agent, on spatial learning and memory in rats. | 2009 | Pharmacol. Biochem. Behav. | pmid:19490927 |
| Zeng S et al. | Formulation, Characterization, and Antitumor Properties of Trans- and Cis-Citral in the 4T1 Breast Cancer Xenograft Mouse Model. | 2015 | Pharm. Res. | pmid:25673043 |
| Lima IO et al. | Anti-Candida albicans effectiveness of citral and investigation of mode of action. | 2012 | Pharm Biol | pmid:23116193 |
| Dangkong D and Limpanasithikul W | Effect of citral on the cytotoxicity of doxorubicin in human B-lymphoma cells. | 2015 | Pharm Biol | pmid:25243873 |
| Han J et al. | Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae. | 2011 | Pest Manag. Sci. | pmid:21674753 |
| Santin MR et al. | In vitro activity of the essential oil of Cymbopogon citratus and its major component (citral) on Leishmania amazonensis. | 2009 | Parasitol. Res. | pmid:19669793 |
| Kumar P et al. | Housefly (Musca domestica L.) control potential of Cymbopogon citratus Stapf. (Poales: Poaceae) essential oil and monoterpenes (citral and 1,8-cineole). | 2013 | Parasitol. Res. | pmid:22955501 |
| Akono Ntonga P et al. | Activity of Ocimum basilicum, Ocimum canum, and Cymbopogon citratus essential oils against Plasmodium falciparum and mature-stage larvae of Anopheles funestus s.s. | 2014 | Parasite | pmid:24995776 |
| Rabbani SI et al. | Citral, a component of lemongrass oil inhibits the clastogenic effect of nickel chloride in mouse micronucleus test system. | 2006 | Pak J Pharm Sci | pmid:16751120 |
| Fukumoto S et al. | Flavor components of monoterpenes in citrus essential oils enhance the release of monoamines from rat brain slices. | 2006 Feb-Apr | Nutr Neurosci | pmid:16913049 |
| Inouye S et al. | Inhibitory activity of hydrosols, herbal teas and related essential oils against filament formation and the growth of Candida albicans. | 2009 | Nihon Ishinkin Gakkai Zasshi | pmid:19942796 |
| Golomb E et al. | Effects of senescence and citral on neuronal vacuolar degeneration in rat pelvic ganglia. | 2001 | Neurotoxicology | pmid:11307853 |
| NTP toxicology and carcinogenesiss studies of citral (microencapsulated) (CAS No. 5392-40-5) in F344/N rats and B6C3F1 mice (feed studies). | 2003 | Natl Toxicol Program Tech Rep Ser | pmid:12637974 | |
| Taherpour AA et al. | Chemical composition analysis of the essential oil of Melissa officinalis L. from Kurdistan, Iran by HS/SPME method and calculation of the biophysicochemical coefficients of the components. | 2012 | Nat. Prod. Res. | pmid:21809949 |
| Sasidharan I et al. | Essential oil composition of two unique ginger (Zingiber officinale Roscoe) cultivars from Sikkim. | 2012 | Nat. Prod. Res. | pmid:21985708 |
| Sekiwa Y et al. | First isolation of geranyl disaccharides from ginger and their relations to aroma formation. | 2001 | Nat Prod Lett | pmid:11833622 |
| Gupta S et al. | Composition of a monoterpenoid-rich essential oil from the rhizome of Zingiber officinale from north western Himalayas. | 2011 | Nat Prod Commun | pmid:21366054 |
| Singh SA et al. | Antibacterial potential of citral derivatives. | 2011 | Nat Prod Commun | pmid:21941882 |
| Gómez LA et al. | Comparative study on in vitro activities of citral, limonene and essential oils from Lippia citriodora and L. alba on yellow fever virus. | 2013 | Nat Prod Commun | pmid:23513741 |
| Kwon JT et al. | Cytotoxic effects of air freshener biocides in lung epithelial cells. | 2013 | Nat Prod Commun | pmid:24273871 |
| Singh S et al. | Monoterpene citral derivatives as potential antimalarials. | 2014 | Nat Prod Commun | pmid:24689199 |
| Abramovici A and Sandbank U | The mortician's mystery solved? | 1988 | N. Engl. J. Med. | pmid:3173450 |
| Viollon C and Chaumont JP | Antifungal properties of essential oils and their main components upon Cryptococcus neoformans. | 1994 | Mycopathologia | pmid:7739729 |
| Gomes-Carneiro MR et al. | Mutagenicity testing (+/-)-camphor, 1,8-cineole, citral, citronellal, (-)-menthol and terpineol with the Salmonella/microsome assay. | 1998 | Mutat. Res. | pmid:9725999 |
| Sandoval-Montemayor NE et al. | Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents. | 2012 | Molecules | pmid:22992784 |
| Reis SL et al. | Typical Monoterpenes as Insecticides and Repellents against Stored Grain Pests. | 2016 | Molecules | pmid:26907246 |
| Espina L et al. | Individual Constituents from Essential Oils Inhibit Biofilm Mass Production by Multi-Drug Resistant Staphylococcus aureus. | 2015 | Molecules | pmid:26102069 |
| Li RY et al. | The natural product citral can cause significant damage to the hyphal cell walls of Magnaporthe grisea. | 2014 | Molecules | pmid:25029074 |
| Pereira SL et al. | Vasodilator activity of the essential oil from aerial parts of Pectis brevipedunculata and its main constituent citral in rat aorta. | 2013 | Molecules | pmid:23470336 |
| Kim E and Park IK | Fumigant antifungal activity of Myrtaceae essential oils and constituents from Leptospermum petersonii against three Aspergillus species. | 2012 | Molecules | pmid:22945026 |
| Raner GM et al. | Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral. | 1996 | Mol. Pharmacol. | pmid:8643091 |
| Zhang M et al. | Proteome alteration of U251 human astrocytoma cell after inhibiting retinoic acid synthesis. | 2009 | Mol. Cell. Biochem. | pmid:19089318 |
| Lindström L et al. | Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors. | 2015 | Mol. Cancer Res. | pmid:25934692 |