Geranial

Geranial is a lipid of Prenol Lipids (PR) class. Geranial is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Oxidation, Process, geranial dehydrogenase activity and retinoid X receptor binding. Geranial often locates in soluble. The associated genes with Geranial are CDKN1A gene.

Cross Reference

Introduction

To understand associated biological information of Geranial, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Geranial?

Geranial is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Geranial

MeSH term MeSH ID Detail
Gastrointestinal Hemorrhage D006471 27 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Geranial

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Geranial?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Geranial?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Geranial?

There are no associated biomedical information in the current reference collection.

What genes are associated with Geranial?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Geranial?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Geranial

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Authors Title Published Journal PubMed Link
Segal R and Milo-Goldzweig I The hemolytic activity of citral--II. Glutathione depletion in citral treated erythrocytes. 1985 Biochem. Pharmacol. pmid:4062979
Tamir I et al. The hemolytic activity of citral: evidence for free radical participation. 1984 Biochem. Pharmacol. pmid:6487347
Katsukawa M et al. Citral, a component of lemongrass oil, activates PPARα and γ and suppresses COX-2 expression. 2010 Biochim. Biophys. Acta pmid:20656057
Tomita S et al. Characteristic properties of a retinoic acid synthetic cytochrome P-450 purified from liver microsomes of 3-methylcholanthrene-induced rats. 1996 Biochim. Biophys. Acta pmid:8765131
Sato K et al. Antimicrobial effect of trans-cinnamaldehyde, (-)-perillaldehyde, (-)-citronellal, citral, eugenol and carvacrol on airborne microbes using an airwasher. 2006 Biol. Pharm. Bull. pmid:17077531
Rajak H et al. Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: a natural product coupled approach to semicarbazones for antiepileptic activity. 2013 Bioorg. Med. Chem. Lett. pmid:23265873
Kashiwayanagi M et al. Membrane fluidity changes of liposomes in response to various odorants. Complexity of membrane composition and variety of adsorption sites for odorants. 1990 Biophys. J. pmid:2248993
Ramachandran S et al. Permeabilization and inhibition of the germination of spores of Aspergillus niger for gluconic acid production from glucose. 2008 Bioresour. Technol. pmid:17889524
Lin CT et al. Anti-inflammation activity of fruit essential oil from Cinnamomum insularimontanum Hayata. 2008 Bioresour. Technol. pmid:18513962
Lin SY et al. Volatile organic components of fresh leaves as indicators of indigenous and cultivated citrus species in Taiwan. 2010 Biosci. Biotechnol. Biochem. pmid:20378980
Rungsardthong Ruktanonchai U et al. Encapsulation of citral isomers in extracted lemongrass oil with cyclodextrins: molecular modeling and physicochemical characterizations. 2011 Biosci. Biotechnol. Biochem. pmid:22146714
Hassan M et al. Monoterpene alcohol metabolism: identification, purification, and characterization of two geraniol dehydrogenase isoenzymes from Polygonum minus leaves. 2012 Biosci. Biotechnol. Biochem. pmid:22878188
Wolken WA et al. Toxicity of terpenes to spores and mycelium of Penicillium digitatum. 2002 Biotechnol. Bioeng. pmid:12378610
Chen Y and Reese DH A screen for disruptors of the retinol (vitamin A) signaling pathway. 2013 Birth Defects Res. B Dev. Reprod. Toxicol. pmid:23696197
OuYang Q et al. Transcriptional profiling analysis of Penicillium digitatum, the causal agent of citrus green mold, unravels an inhibited ergosterol biosynthesis pathway in response to citral. 2016 BMC Genomics pmid:27514516
Annadurai RS et al. Next generation sequencing and de novo transcriptome analysis of Costus pictus D. Don, a non-model plant with potent anti-diabetic properties. 2012 BMC Genomics pmid:23176672
Youngentob SL and Kent PF Enhancement of odorant-induced mucosal activity patterns in rats trained on an odorant identification task. 1995 Brain Res. pmid:7719728
Prince DJ and Carlone RL Retinoic acid involvement in the reciprocal neurotrophic interactions between newt spinal cord and limb blastemas in vitro. 2003 Brain Res. Dev. Brain Res. pmid:12524177
Pompeu MS and Silveira FA Reaction of Melipona rufiventris lepeletier to citral and against an attack by the Cleptobiotic bee Lestrimelitta limao (Smith) (Hymenoptera: Apidae: Meliponina). 2005 Braz J Biol pmid:16025918
Silva Cde B et al. Antifungal activity of the lemongrass oil and citral against Candida spp. 2008 Braz J Infect Dis pmid:18553017
Ara K et al. Foot odor due to microbial metabolism and its control. 2006 Can. J. Microbiol. pmid:16699586
Queiroz RM et al. Apoptosis-inducing effects of Melissa officinalis L. essential oil in glioblastoma multiforme cells. 2014 Cancer Invest. pmid:24745610
Connor MJ Modulation of tumor promotion in mouse skin by the food additive citral (3,7-dimethyl-2,6-octadienal). 1991 Cancer Lett. pmid:2004350
Connor MJ Oxidation of retinol to retinoic acid as a requirement for biological activity in mouse epidermis. 1988 Cancer Res. pmid:3191479
Binder S et al. Adverse Phototoxic Effect of Essential Plant Oils on NIH 3T3 Cell Line after UV Light Exposure. 2016 Cent. Eur. J. Public Health pmid:27755863
Iersel ML et al. Inhibition of glutathione S-transferase activity in human melanoma cells by alpha,beta-unsaturated carbonyl derivatives. Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal. 1996 Chem. Biol. Interact. pmid:8950226
Seo KA et al. The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity. 2008 Chem. Biol. Interact. pmid:18611395
Bchini R et al. Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition. 2013 Chem. Biol. Interact. pmid:23220587
Li J et al. Transient transmembrane secretion of H2O2: a mechanism for the citral-caused inhibition of aflatoxin production from Aspergillus flavus. 2015 Chem. Commun. (Camb.) pmid:26466766
Milone C et al. Selective liquid phase hydrogenation of citral on Au/Fe2O3 catalysts. 2002 Chem. Commun. (Camb.) pmid:12123019
Merckel F et al. Effect of a microemulsion system on hapten-peptide reactivity studies: examples of hydroxycitronellal and citral, fragrance skin sensitizers, with glutathione. 2010 Chem. Res. Toxicol. pmid:20795681
Hagvall L et al. Experimental and theoretical investigations of the autoxidation of geranial: a dioxolane hydroperoxide identified as a skin sensitizer. 2011 Chem. Res. Toxicol. pmid:21823635
Laska M and Grimm N SURE, why not? The SUbstitution-REciprocity method for measurement of odor quality discrimination thresholds: replication and extension to nonhuman primates. 2003 Chem. Senses pmid:12588733
Veldhuizen MG et al. Coactivation of gustatory and olfactory signals in flavor perception. 2010 Chem. Senses pmid:20032112
Takiguchi N et al. Performance of mice in discrimination of liquor odors: behavioral evidence for olfactory attention. 2008 Chem. Senses pmid:18178544
Hallowell ES et al. Flavor Identification and Intensity: Effects of Stimulus Context. 2016 Chem. Senses pmid:26830499
Shepard TG et al. Response Times to Gustatory-Olfactory Flavor Mixtures: Role of Congruence. 2015 Chem. Senses pmid:26304508
Brewer JM et al. Identification of gustatory-olfactory flavor mixtures: effects of linguistic labeling. 2013 Chem. Senses pmid:23329730
Osada K et al. Evaluation of the masking of dimethyl sulfide odors by citronellal, limonene and citral through the use of trained odor sensor mice. 2013 Chem. Senses pmid:23071142
Brossard C et al. Perceptual interactions between characteristic notes smelled above aqueous solutions of odorant mixtures. 2007 Chem. Senses pmid:17301061
Gallert T et al. Microwave-assisted partial hydrogenation of citral by using ionic liquid-coated porous glass catalysts. 2011 ChemSusChem pmid:21826800
Engelstein D et al. Citral and testosterone interactions in inducing benign and atypical prostatic hyperplasia in rats. 1996 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:9568365
Heydorn S et al. Citral a fragrance allergen and irritant. 2003 Contact Derm. pmid:14641118
Heydorn S et al. Fragrance allergy in patients with hand eczema - a clinical study. 2003 Contact Derm. pmid:14531870
Bakker CV et al. Ascaridole, a sensitizing component of tea tree oil, patch tested at 1% and 5% in two series of patients. 2011 Contact Derm. pmid:21906073
Frosch PJ et al. Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix. 2005 Contact Derm. pmid:15859993
Frosch PJ et al. Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products. 2005 Contact Derm. pmid:15859994
Frosch PJ et al. Patch testing with fragrances: results of a multicenter study of the European Environmental and Contact Dermatitis Research Group with 48 frequently used constituents of perfumes. 1995 Contact Derm. pmid:8565489
Hagvall L et al. Contact allergy to air-exposed geraniol: clinical observations and report of 14 cases. 2012 Contact Derm. pmid:22681463
Rastogi SC et al. Natural ingredients based cosmetics. Content of selected fragrance sensitizers. 1996 Contact Derm. pmid:8879930