Aucubin

Aucubin is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 633 references associated with Aucubin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Chiang LC et al. Antileukemic activity of selected natural products in Taiwan. 2003 Am. J. Chin. Med. pmid:12723753
Chiang LC et al. Antiviral activity of Plantago major extracts and related compounds in vitro. 2002 Antiviral Res. pmid:12076751
Lee DH et al. Studies on the possible mechanisms of protective activity against alpha-amanitin poisoning by aucubin. 2001 Arch. Pharm. Res. pmid:11235813
DUFF RB et al. CATALPOL AND METHYLCATALPOL: NATURALLY OCCURRING GLYCOSIDES IN PLANTAGO AND BUDDLEIA SPECIES. 1965 Biochem. J. pmid:14343132
TRIM AR and HILL R The preparation and properties of aucubin, asperuloside and some related glycosides. 1952 Biochem. J. pmid:14915951
Ho JN et al. Protective effects of aucubin isolated from Eucommia ulmoides against UVB-induced oxidative stress in human skin fibroblasts. 2005 Biol. Pharm. Bull. pmid:15997107
Andoh T et al. Prophylactic Administration of Aucubin Inhibits Paclitaxel-Induced Mechanical Allodynia via the Inhibition of Endoplasmic Reticulum Stress in Peripheral Schwann Cells. 2017 Biol. Pharm. Bull. pmid:28381802
Oku H et al. Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica. 2011 Biol. Pharm. Bull. pmid:21804227
Li Y et al. The promoting effects of geniposidic acid and aucubin in Eucommia ulmoides Oliver leaves on collagen synthesis. 1998 Biol. Pharm. Bull. pmid:9881644
Xu W et al. A rapid and sensitive determination of aucubin in rat plasma by liquid chromatography-tandem mass spectrometry and its pharmacokinetic application. 2012 Biomed. Chromatogr. pmid:22113886
Ho JN et al. Inhibitory effect of Aucubin isolated from Eucommia ulmoides against UVB-induced matrix metalloproteinase-1 production in human skin fibroblasts. 2005 Biosci. Biotechnol. Biochem. pmid:16306708
Ong VY and Tan BK Novel phytoandrogens and lipidic augmenters from Eucommia ulmoides. 2007 BMC Complement Altern Med pmid:17261169
Ali N et al. Anthelmintic and relaxant activities of Verbascum Thapsus Mullein. 2012 BMC Complement Altern Med pmid:22463730
Young IC et al. Protective effects of aucubin on osteoarthritic chondrocyte model induced by hydrogen peroxide and mechanical stimulus. 2017 BMC Complement Altern Med pmid:28153003
Li Y et al. X-ray crystal structure of iridoid glucoside aucubin and its aglycone. 2009 Carbohydr. Res. pmid:19762008
Mouriès C et al. Synthesis and cytotoxicity of a novel iridoid glucoside derived from aucubin. 2005 Chem. Biodivers. pmid:17192013
Harput US et al. Iridoid glucosides from Veronica hederifolia. 2002 Chem. Pharm. Bull. pmid:12192146
Harput US et al. Phenylethanoid and iridoid glycosides from Veronica persica. 2002 Chem. Pharm. Bull. pmid:12045353
Lemus C et al. Lewis acid catalyzed enlargement of cyclic β-alkoxyenals and one-pot synthesis of polyfunctional enoxysilanes derived from aucubin with trimethylsilyldiazomethane. 2013 Chemistry pmid:23450668
Feng Y et al. Chinese medicines as a resource for liver fibrosis treatment. 2009 Chin Med pmid:19695098
Liao JF et al. Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components. 2011 Chin Med pmid:21320305
Hung JY et al. Antiproliferative activity of aucubin is through cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18430063
Ou JS et al. A potential agent for treating non-small cell lung cancer. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18782201
Jeong HJ et al. Inhibition of TNF-alpha and IL-6 production by Aucubin through blockade of NF-kappaB activation RBL-2H3 mast cells. 2002 Cytokine pmid:12161100
Park KS Aucubin, a naturally occurring iridoid glycoside inhibits TNF-α-induced inflammatory responses through suppression of NF-κB activation in 3T3-L1 adipocytes. 2013 Cytokine pmid:23612013
Chang IM et al. Protective activities of aucubin against carbon tetrachloride-induced liver damage in mice. 1983 Drug Chem Toxicol pmid:6194953
Suomi J et al. Determination of iridoid glycosides by micellar electrokinetic capillary chromatography-mass spectrometry with use of the partial filling technique. 2001 Electrophoresis pmid:11519962
Rakotondramasy VC et al. A novel series of cytotoxic iridoid glucosides derived from aucubin: design, synthesis and structure-activity relationships. 2010 Eur J Med Chem pmid:20227146
Jin L et al. Antioxidant and pancreas-protective effect of aucubin on rats with streptozotocin-induced diabetes. 2008 Eur. J. Pharmacol. pmid:18230397
Park KS et al. Inhibitory Potencies of Several Iridoids on Cyclooxygenase-1, Cyclooxygnase-2 Enzymes Activities, Tumor Necrosis factor-α and Nitric Oxide Production In Vitro. 2010 Evid Based Complement Alternat Med pmid:18955286
Ho M et al. The Association between Traditional Chinese Dietary and Herbal Therapies and Uterine Involution in Postpartum Women. 2011 Evid Based Complement Alternat Med pmid:21584195
McCarthy E and O'Mahony JM What's in a Name? Can Mullein Weed Beat TB Where Modern Drugs Are Failing? 2011 Evid Based Complement Alternat Med pmid:20953419
Wen KC et al. Ixora parviflora Protects against UVB-Induced Photoaging by Inhibiting the Expression of MMPs, MAP Kinases, and COX-2 and by Promoting Type I Procollagen Synthesis. 2012 Evid Based Complement Alternat Med pmid:22203872
Háznagy-Radnai E et al. Cytotoxic activities of Stachys species. 2008 Fitoterapia pmid:18672034
Peng MJ et al. [Study on optimizing the analysis condition for active compound in Eucommia olive]. 2004 Guang Pu Xue Yu Guang Pu Fen Xi pmid:15828353
Shim KM et al. Effects of aucubin on the healing of oral wounds. 2007 Nov-Dec In Vivo pmid:18210752
Rathod NR et al. Free Radical Scavenging Activity of Calotropis gigantea on Streptozotocin-Induced Diabetic Rats. 2009 Indian J Pharm Sci pmid:20376213
Pankoke H et al. The interplay between toxin-releasing β-glucosidase and plant iridoid glycosides impairs larval development in a generalist caterpillar, Grammia incorrupta (Arctiidae). 2012 Insect Biochem. Mol. Biol. pmid:22446106
Yao Y et al. Major phenolic compounds, antioxidant capacity and antidiabetic potential of rice bean (Vigna umbellata L.) in China. 2012 Int J Mol Sci pmid:22489119
Yao Y et al. Biological potential of sixteen legumes in China. 2011 Int J Mol Sci pmid:22072935
Ben Jilani KE et al. Overexpression of selenoprotein H reduces Ht22 neuronal cell death after UVB irradiation by preventing superoxide formation. 2007 Int. J. Biol. Sci. pmid:17389926
Suomi J et al. Extraction of iridoid glycosides and their determination by micellar electrokinetic capillary chromatography. 2000 J Chromatogr A pmid:10677081
Gálvez M et al. Iridoids as DNA topoisomerase I poisons. 2005 J Enzyme Inhib Med Chem pmid:16206835
Kunwar RM et al. Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. 2010 J Ethnobiol Ethnomed pmid:21144003
Kim BH et al. Elucidation of anti-inflammatory potencies of Eucommia ulmoides bark and Plantago asiatica seeds. 2009 J Med Food pmid:19735174
Jeong HJ et al. Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism. 2010 J Neuroinflammation pmid:21108840
Zhao Y et al. The experimental study of Cortex Eucommiae on meridian tropsim: the distribution study of aucubin in rat tissues. 2008 J Pharm Biomed Anal pmid:17988817
Wang Q et al. HPLC-APCI-MS/MS method for the determination of catalpol in rat plasma and cerebrospinal fluid: application to an in vivo pharmacokinetic study. 2012 J Pharm Biomed Anal pmid:22677654
Vargas S et al. Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation. 2011 J Pharm Biomed Anal pmid:21872416
Tamura Y and Nishibe S Changes in the concentrations of bioactive compounds in plantain leaves. 2002 J. Agric. Food Chem. pmid:11958614
Wurst S et al. Earthworms and litter distribution affect plant-defensive chemistry. 2004 J. Chem. Ecol. pmid:15260217
Reudler JH et al. Differential performance of a specialist and two generalist herbivores and their parasitoids on Plantago lanceolata. 2011 J. Chem. Ecol. pmid:21691810
Fuchs A and Bowers MD Patterns of iridoid glycoside production and induction in Plantago lanceolata and the importance of plant age. 2004 J. Chem. Ecol. pmid:15586671
Baden CU et al. Host dependent iridoid glycoside sequestration patterns in Cionus hortulanus. 2013 J. Chem. Ecol. pmid:23846185
Richards LA et al. Synergistic effects of iridoid glycosides on the survival, development and immune response of a specialist caterpillar, Junonia coenia (Nymphalidae). 2012 J. Chem. Ecol. pmid:23053916
Reudler Talsma JH et al. Oviposition cues for a specialist butterfly--plant chemistry and size. 2008 J. Chem. Ecol. pmid:18612691
Fontana A et al. The effects of arbuscular mycorrhizal fungi on direct and indirect defense metabolites of Plantago lanceolata L. 2009 J. Chem. Ecol. pmid:19568812