Aucubin

Aucubin is a lipid of Prenol Lipids (PR) class.

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Current reference collection contains 633 references associated with Aucubin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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TRIM AR and HILL R The preparation and properties of aucubin, asperuloside and some related glycosides. 1952 Biochem. J. pmid:14915951
DUFF RB et al. CATALPOL AND METHYLCATALPOL: NATURALLY OCCURRING GLYCOSIDES IN PLANTAGO AND BUDDLEIA SPECIES. 1965 Biochem. J. pmid:14343132
Chang IM et al. Protective activities of aucubin against carbon tetrachloride-induced liver damage in mice. 1983 Drug Chem Toxicol pmid:6194953
Chang LM et al. Aucubin: potential antidote for alpha-amanitin poisoning. 1984 J. Toxicol. Clin. Toxicol. pmid:6208374
Guo Y et al. [Determination of aucubin in Plantago asiatica L., P. major L. and P. depressa Willd. by HPLC]. 1991 Zhongguo Zhong Yao Za Zhi pmid:1811672
Suh NJ et al. Pharmacokinetic study of an iridoid glucoside: aucubin. 1991 Pharm. Res. pmid:1924160
Ortiz de Urbina AV et al. In vitro antispasmodic activity of peracetylated penstemonoside, aucubin and catalpol. 1994 Planta Med. pmid:7809202
Bartholomaeus A and Ahokas J Inhibition of P-450 by aucubin: is the biological activity of aucubin due to its glutaraldehyde-like aglycone? 1995 Toxicol. Lett. pmid:7482595
Chang IM Liver-protective activities of aucubin derived from traditional oriental medicine. 1998 Res. Commun. Mol. Pathol. Pharmacol. pmid:10100510
Li Y et al. The promoting effects of geniposidic acid and aucubin in Eucommia ulmoides Oliver leaves on collagen synthesis. 1998 Biol. Pharm. Bull. pmid:9881644
Suomi J et al. Extraction of iridoid glycosides and their determination by micellar electrokinetic capillary chromatography. 2000 J Chromatogr A pmid:10677081
Kim DH et al. Mechanism of covalent adduct formation of aucubin to proteins. 2000 Toxicol. Lett. pmid:10713483
Lee DH et al. Studies on the possible mechanisms of protective activity against alpha-amanitin poisoning by aucubin. 2001 Arch. Pharm. Res. pmid:11235813
Suomi J et al. Determination of iridoid glycosides by micellar electrokinetic capillary chromatography-mass spectrometry with use of the partial filling technique. 2001 Electrophoresis pmid:11519962
Jeong HJ et al. Inhibition of TNF-alpha and IL-6 production by Aucubin through blockade of NF-kappaB activation RBL-2H3 mast cells. 2002 Cytokine pmid:12161100
Tamura Y and Nishibe S Changes in the concentrations of bioactive compounds in plantain leaves. 2002 J. Agric. Food Chem. pmid:11958614
Chiang LC et al. Antiviral activity of Plantago major extracts and related compounds in vitro. 2002 Antiviral Res. pmid:12076751
Harput US et al. Iridoid glucosides from Veronica hederifolia. 2002 Chem. Pharm. Bull. pmid:12192146
Harput US et al. Phenylethanoid and iridoid glycosides from Veronica persica. 2002 Chem. Pharm. Bull. pmid:12045353
Cimanga K et al. Complement-inhibiting iridoids from Morinda morindoides. 2003 J. Nat. Prod. pmid:12542353
Chiang LC et al. Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species. 2003 Planta Med. pmid:12898413
Chiang LC et al. Antileukemic activity of selected natural products in Taiwan. 2003 Am. J. Chin. Med. pmid:12723753
Park KS and Chang IM Anti-inflammatory activity of aucubin by inhibition of tumor necrosis factor-alpha production in RAW 264.7 cells. 2004 Planta Med. pmid:15326552
Wurst S et al. Earthworms and litter distribution affect plant-defensive chemistry. 2004 J. Chem. Ecol. pmid:15260217
Biere A et al. Plant chemical defense against herbivores and pathogens: generalized defense or trade-offs? 2004 Oecologia pmid:15146326
Peng MJ et al. [Study on optimizing the analysis condition for active compound in Eucommia olive]. 2004 Guang Pu Xue Yu Guang Pu Fen Xi pmid:15828353
Fuchs A and Bowers MD Patterns of iridoid glycoside production and induction in Plantago lanceolata and the importance of plant age. 2004 J. Chem. Ecol. pmid:15586671
Jurisić R et al. Determination of aucubin and catalpol in Plantago species by micellar electrokinetic chromatography. 2004 Jan-Feb Z. Naturforsch., C, J. Biosci. pmid:15018047
Ho JN et al. Inhibitory effect of Aucubin isolated from Eucommia ulmoides against UVB-induced matrix metalloproteinase-1 production in human skin fibroblasts. 2005 Biosci. Biotechnol. Biochem. pmid:16306708
Gálvez M et al. Antioxidant activity of Plantago bellardii All. 2005 Phytother Res pmid:16372378
Ho JN et al. Protective effects of aucubin isolated from Eucommia ulmoides against UVB-induced oxidative stress in human skin fibroblasts. 2005 Biol. Pharm. Bull. pmid:15997107
Zhang Y et al. [Study on the chemical constituents of Buddleja purdomii]. 2005 Zhong Yao Cai pmid:16514886
Gálvez M et al. Iridoids as DNA topoisomerase I poisons. 2005 J Enzyme Inhib Med Chem pmid:16206835
Mouriès C et al. Synthesis and cytotoxicity of a novel iridoid glucoside derived from aucubin. 2005 Chem. Biodivers. pmid:17192013
Ramunno A et al. Taxonomical markers in two endemic plants of Sardinia: Verbascum conocarpum and Scrophularia trifoliata. 2006 Nat. Prod. Res. pmid:16644551
Ong VY and Tan BK Novel phytoandrogens and lipidic augmenters from Eucommia ulmoides. 2007 BMC Complement Altern Med pmid:17261169
Rakotondramasy VC et al. Regioselective and stereospecific amination of iridoids: conversion of aucubin into aminoside antibiotic analogues. 2007 J. Nat. Prod. pmid:17253843
Zhao XM et al. [Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction]. 2007 Zhongguo Zhong Yao Za Zhi pmid:18309665
Kang Z et al. [Research advances in pharmacology of aucubin and aucubigenin]. 2007 Zhongguo Zhong Yao Za Zhi pmid:18338591
Ben Jilani KE et al. Overexpression of selenoprotein H reduces Ht22 neuronal cell death after UVB irradiation by preventing superoxide formation. 2007 Int. J. Biol. Sci. pmid:17389926
Bae JY et al. Protective actions of Rubus coreanus ethanol extract on collagenous extracellular matrix in ultraviolet-B irradiation-induced human dermal fibroblasts. 2007 Nutr Res Pract pmid:20368951
Fleer H and Verspohl EJ Antispasmodic activity of an extract from Plantago lanceolata L. and some isolated compounds. 2007 Phytomedicine pmid:17298877
Shim KM et al. Effects of aucubin on the healing of oral wounds. 2007 Nov-Dec In Vivo pmid:18210752
Zhao Y et al. The experimental study of Cortex Eucommiae on meridian tropsim: the distribution study of aucubin in rat tissues. 2008 J Pharm Biomed Anal pmid:17988817
Jin L et al. Antioxidant and pancreas-protective effect of aucubin on rats with streptozotocin-induced diabetes. 2008 Eur. J. Pharmacol. pmid:18230397
Hung JY et al. Antiproliferative activity of aucubin is through cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18430063
Háznagy-Radnai E et al. Cytotoxic activities of Stachys species. 2008 Fitoterapia pmid:18672034
Xue H et al. Neuroprotection of aucubin in primary diabetic encephalopathy. 2008 Sci. China, C, Life Sci. pmid:18488169
Ou JS et al. A potential agent for treating non-small cell lung cancer. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18782201
Reudler Talsma JH et al. Oviposition cues for a specialist butterfly--plant chemistry and size. 2008 J. Chem. Ecol. pmid:18612691
Ibrahim NA et al. Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruits growing in Egypt. 2008 Nat. Prod. Res. pmid:18415863
Kim BH et al. Elucidation of anti-inflammatory potencies of Eucommia ulmoides bark and Plantago asiatica seeds. 2009 J Med Food pmid:19735174
Li Y et al. X-ray crystal structure of iridoid glucoside aucubin and its aglycone. 2009 Carbohydr. Res. pmid:19762008
Xue HY et al. Aucubin prevents loss of hippocampal neurons and regulates antioxidative activity in diabetic encephalopathy rats. 2009 Phytother Res pmid:19140154
Bennett AE et al. Arbuscular mycorrhizal fungal species suppress inducible plant responses and alter defensive strategies following herbivory. 2009 Oecologia pmid:19408016
Yang R et al. [Hairy root culture optimization and aucubin medical composition production of Eucommia ulmoides]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19894530
Fontana A et al. The effects of arbuscular mycorrhizal fungi on direct and indirect defense metabolites of Plantago lanceolata L. 2009 J. Chem. Ecol. pmid:19568812