| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Andoh T et al. | Prophylactic Administration of Aucubin Inhibits Paclitaxel-Induced Mechanical Allodynia via the Inhibition of Endoplasmic Reticulum Stress in Peripheral Schwann Cells. | 2017 | Biol. Pharm. Bull. | pmid:28381802 |
| Young IC et al. | Protective effects of aucubin on osteoarthritic chondrocyte model induced by hydrogen peroxide and mechanical stimulus. | 2017 | BMC Complement Altern Med | pmid:28153003 |
| Lee GH et al. | Eucommia ulmoides cortex, geniposide and aucubin regulate lipotoxicity through the inhibition of lysosomal BAX. | 2014 | PLoS ONE | pmid:24586300 |
| Kumar V et al. | A proposed biosynthetic pathway of picrosides linked through the detection of biochemical intermediates in the endangered medicinal herb Picrorhiza kurroa. | 2013 Nov-Dec | Phytochem Anal | pmid:23696248 |
| Venditti A et al. | Phytochemical composition of polar fraction of Stachys germanica L. subsp. salviifolia (Ten.) Gams, a typical plant of Majella National Park. | 2013 | Nat. Prod. Res. | pmid:22372659 |
| Lemus C et al. | Lewis acid catalyzed enlargement of cyclic β-alkoxyenals and one-pot synthesis of polyfunctional enoxysilanes derived from aucubin with trimethylsilyldiazomethane. | 2013 | Chemistry | pmid:23450668 |
| Baden CU et al. | Host dependent iridoid glycoside sequestration patterns in Cionus hortulanus. | 2013 | J. Chem. Ecol. | pmid:23846185 |
| Pankoke H et al. | Role of plant β-glucosidases in the dual defense system of iridoid glycosides and their hydrolyzing enzymes in Plantago lanceolata and Plantago major. | 2013 | Phytochemistry | pmid:23773298 |
| Park KS | Aucubin, a naturally occurring iridoid glycoside inhibits TNF-α-induced inflammatory responses through suppression of NF-κB activation in 3T3-L1 adipocytes. | 2013 | Cytokine | pmid:23612013 |
| Lee HY et al. | Eucommia ulmoides Oliver extract, aucubin, and geniposide enhance lysosomal activity to regulate ER stress and hepatic lipid accumulation. | 2013 | PLoS ONE | pmid:24349058 |
| Gonda S et al. | Effect of high relative humidity on dried Plantago lanceolata L. leaves during long-term storage: effects on chemical composition, colour and microbiological quality. | 2012 Jan-Feb | Phytochem Anal | pmid:21618310 |
| Yao Y et al. | Major phenolic compounds, antioxidant capacity and antidiabetic potential of rice bean (Vigna umbellata L.) in China. | 2012 | Int J Mol Sci | pmid:22489119 |
| Xu W et al. | A rapid and sensitive determination of aucubin in rat plasma by liquid chromatography-tandem mass spectrometry and its pharmacokinetic application. | 2012 | Biomed. Chromatogr. | pmid:22113886 |
| Háznagy-Radnai E et al. | Antiinflammatory activities of Hungarian Stachys species and their iridoids. | 2012 | Phytother Res | pmid:21887806 |
| Xue HY et al. | Protective effects of aucubin on Hâ‚‚Oâ‚‚-induced apoptosis in PC12 cells. | 2012 | Phytother Res | pmid:21728203 |
| Xue HY et al. | Neuroprotective properties of aucubin in diabetic rats and diabetic encephalopathy rats. | 2012 | Mol. Biol. Rep. | pmid:22810648 |
| Pankoke H et al. | The interplay between toxin-releasing β-glucosidase and plant iridoid glycosides impairs larval development in a generalist caterpillar, Grammia incorrupta (Arctiidae). | 2012 | Insect Biochem. Mol. Biol. | pmid:22446106 |
| Zheng J et al. | [Enzymatic extraction and antibacterial activity of aucubin from Eucommia ulmoides leaves]. | 2012 | Zhong Yao Cai | pmid:22822679 |
| Richards LA et al. | Synergistic effects of iridoid glycosides on the survival, development and immune response of a specialist caterpillar, Junonia coenia (Nymphalidae). | 2012 | J. Chem. Ecol. | pmid:23053916 |
| Venditti A et al. | Phytochemical analysis of Plantago sempervirens from Majella National Park. | 2012 | Nat. Prod. Res. | pmid:22081901 |
| Liu Z et al. | Simultaneous determination of four bioactive compounds in Verbena officinalis L. by using high-performance liquid chromatography. | 2012 | Pharmacogn Mag | pmid:22701291 |
| Opitz SE et al. | Host shifts from Lamiales to Brassicaceae in the sawfly genus Athalia. | 2012 | PLoS ONE | pmid:22485146 |
| Ali N et al. | Anthelmintic and relaxant activities of Verbascum Thapsus Mullein. | 2012 | BMC Complement Altern Med | pmid:22463730 |
| Wang Q et al. | HPLC-APCI-MS/MS method for the determination of catalpol in rat plasma and cerebrospinal fluid: application to an in vivo pharmacokinetic study. | 2012 | J Pharm Biomed Anal | pmid:22677654 |
| Wen KC et al. | Ixora parviflora Protects against UVB-Induced Photoaging by Inhibiting the Expression of MMPs, MAP Kinases, and COX-2 and by Promoting Type I Procollagen Synthesis. | 2012 | Evid Based Complement Alternat Med | pmid:22203872 |
| Xue HY et al. | Aucubin modulates Bcl-2 family proteins expression and inhibits caspases cascade in Hâ‚‚Oâ‚‚-induced PC12 cells. | 2011 | Mol. Biol. Rep. | pmid:21120620 |
| Reudler JH et al. | Differential performance of a specialist and two generalist herbivores and their parasitoids on Plantago lanceolata. | 2011 | J. Chem. Ecol. | pmid:21691810 |
| Mraja A et al. | Plant community diversity influences allocation to direct chemical defence in Plantago lanceolata. | 2011 | PLoS ONE | pmid:22174766 |
| Yao Y et al. | Biological potential of sixteen legumes in China. | 2011 | Int J Mol Sci | pmid:22072935 |
| Ho M et al. | The Association between Traditional Chinese Dietary and Herbal Therapies and Uterine Involution in Postpartum Women. | 2011 | Evid Based Complement Alternat Med | pmid:21584195 |
| Liao JF et al. | Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components. | 2011 | Chin Med | pmid:21320305 |
| McCarthy E and O'Mahony JM | What's in a Name? Can Mullein Weed Beat TB Where Modern Drugs Are Failing? | 2011 | Evid Based Complement Alternat Med | pmid:20953419 |
| Oku H et al. | Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica. | 2011 | Biol. Pharm. Bull. | pmid:21804227 |
| Kirmizibekmez H et al. | Antiprotozoal activity of Melampyrum arvense and its metabolites. | 2011 | Phytother Res | pmid:20623589 |
| Zhang R et al. | Antidiabetic activity of isoquercetin in diabetic KK -Ay mice. | 2011 | Nutr Metab (Lond) | pmid:22133267 |
| Vargas S et al. | Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation. | 2011 | J Pharm Biomed Anal | pmid:21872416 |
| Kim Y et al. | Novel PI3K/Akt inhibitors screened by the cytoprotective function of human immunodeficiency virus type 1 Tat. | 2011 | PLoS ONE | pmid:21765914 |
| Rakotondramasy VC et al. | A novel series of cytotoxic iridoid glucosides derived from aucubin: design, synthesis and structure-activity relationships. | 2010 | Eur J Med Chem | pmid:20227146 |
| Jeong HJ et al. | Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism. | 2010 | J Neuroinflammation | pmid:21108840 |
| Park KS et al. | Inhibitory Potencies of Several Iridoids on Cyclooxygenase-1, Cyclooxygnase-2 Enzymes Activities, Tumor Necrosis factor-α and Nitric Oxide Production In Vitro. | 2010 | Evid Based Complement Alternat Med | pmid:18955286 |
| Song WB et al. | Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation. | 2010 | PLoS ONE | pmid:20885979 |
| Kunwar RM et al. | Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. | 2010 | J Ethnobiol Ethnomed | pmid:21144003 |
| Kim BH et al. | Elucidation of anti-inflammatory potencies of Eucommia ulmoides bark and Plantago asiatica seeds. | 2009 | J Med Food | pmid:19735174 |
| Li Y et al. | X-ray crystal structure of iridoid glucoside aucubin and its aglycone. | 2009 | Carbohydr. Res. | pmid:19762008 |
| Xue HY et al. | Aucubin prevents loss of hippocampal neurons and regulates antioxidative activity in diabetic encephalopathy rats. | 2009 | Phytother Res | pmid:19140154 |
| Bennett AE et al. | Arbuscular mycorrhizal fungal species suppress inducible plant responses and alter defensive strategies following herbivory. | 2009 | Oecologia | pmid:19408016 |
| Yang R et al. | [Hairy root culture optimization and aucubin medical composition production of Eucommia ulmoides]. | 2009 | Zhongguo Zhong Yao Za Zhi | pmid:19894530 |
| Feng Y et al. | Chinese medicines as a resource for liver fibrosis treatment. | 2009 | Chin Med | pmid:19695098 |
| Lu R et al. | Quantitation of catalpol in rat plasma by liquid chromatography/electrospray ionization tandem mass spectrometry and its pharmacokinetic study. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19744895 |
| Rathod NR et al. | Free Radical Scavenging Activity of Calotropis gigantea on Streptozotocin-Induced Diabetic Rats. | 2009 | Indian J Pharm Sci | pmid:20376213 |
| Li J et al. | Study of chemical composition and antimicrobial activity of leaves and roots of Scrophularia ningpoensis. | 2009 | Nat. Prod. Res. | pmid:19418360 |
| Fontana A et al. | The effects of arbuscular mycorrhizal fungi on direct and indirect defense metabolites of Plantago lanceolata L. | 2009 | J. Chem. Ecol. | pmid:19568812 |
| Sohn SH et al. | The genome-wide expression profile of Scrophularia ningpoensis-treated thapsigargin-stimulated U-87MG cells. | 2009 | Neurotoxicology | pmid:19442820 |
| Zhao Y et al. | The experimental study of Cortex Eucommiae on meridian tropsim: the distribution study of aucubin in rat tissues. | 2008 | J Pharm Biomed Anal | pmid:17988817 |
| Jin L et al. | Antioxidant and pancreas-protective effect of aucubin on rats with streptozotocin-induced diabetes. | 2008 | Eur. J. Pharmacol. | pmid:18230397 |
| Hung JY et al. | Antiproliferative activity of aucubin is through cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells. | 2008 | Clin. Exp. Pharmacol. Physiol. | pmid:18430063 |
| Háznagy-Radnai E et al. | Cytotoxic activities of Stachys species. | 2008 | Fitoterapia | pmid:18672034 |
| Xue H et al. | Neuroprotection of aucubin in primary diabetic encephalopathy. | 2008 | Sci. China, C, Life Sci. | pmid:18488169 |
| Ou JS et al. | A potential agent for treating non-small cell lung cancer. | 2008 | Clin. Exp. Pharmacol. Physiol. | pmid:18782201 |
| Reudler Talsma JH et al. | Oviposition cues for a specialist butterfly--plant chemistry and size. | 2008 | J. Chem. Ecol. | pmid:18612691 |
| Ibrahim NA et al. | Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruits growing in Egypt. | 2008 | Nat. Prod. Res. | pmid:18415863 |
| Shim KM et al. | Effects of aucubin on the healing of oral wounds. | 2007 Nov-Dec | In Vivo | pmid:18210752 |
| Ong VY and Tan BK | Novel phytoandrogens and lipidic augmenters from Eucommia ulmoides. | 2007 | BMC Complement Altern Med | pmid:17261169 |
| Rakotondramasy VC et al. | Regioselective and stereospecific amination of iridoids: conversion of aucubin into aminoside antibiotic analogues. | 2007 | J. Nat. Prod. | pmid:17253843 |
| Zhao XM et al. | [Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:18309665 |
| Kang Z et al. | [Research advances in pharmacology of aucubin and aucubigenin]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:18338591 |
| Ben Jilani KE et al. | Overexpression of selenoprotein H reduces Ht22 neuronal cell death after UVB irradiation by preventing superoxide formation. | 2007 | Int. J. Biol. Sci. | pmid:17389926 |
| Bae JY et al. | Protective actions of Rubus coreanus ethanol extract on collagenous extracellular matrix in ultraviolet-B irradiation-induced human dermal fibroblasts. | 2007 | Nutr Res Pract | pmid:20368951 |
| Fleer H and Verspohl EJ | Antispasmodic activity of an extract from Plantago lanceolata L. and some isolated compounds. | 2007 | Phytomedicine | pmid:17298877 |
| Ramunno A et al. | Taxonomical markers in two endemic plants of Sardinia: Verbascum conocarpum and Scrophularia trifoliata. | 2006 | Nat. Prod. Res. | pmid:16644551 |
| Ho JN et al. | Inhibitory effect of Aucubin isolated from Eucommia ulmoides against UVB-induced matrix metalloproteinase-1 production in human skin fibroblasts. | 2005 | Biosci. Biotechnol. Biochem. | pmid:16306708 |
| Gálvez M et al. | Antioxidant activity of Plantago bellardii All. | 2005 | Phytother Res | pmid:16372378 |
| Ho JN et al. | Protective effects of aucubin isolated from Eucommia ulmoides against UVB-induced oxidative stress in human skin fibroblasts. | 2005 | Biol. Pharm. Bull. | pmid:15997107 |
| Zhang Y et al. | [Study on the chemical constituents of Buddleja purdomii]. | 2005 | Zhong Yao Cai | pmid:16514886 |
| Gálvez M et al. | Iridoids as DNA topoisomerase I poisons. | 2005 | J Enzyme Inhib Med Chem | pmid:16206835 |
| Mouriès C et al. | Synthesis and cytotoxicity of a novel iridoid glucoside derived from aucubin. | 2005 | Chem. Biodivers. | pmid:17192013 |
| Jurisić R et al. | Determination of aucubin and catalpol in Plantago species by micellar electrokinetic chromatography. | 2004 Jan-Feb | Z. Naturforsch., C, J. Biosci. | pmid:15018047 |
| Park KS and Chang IM | Anti-inflammatory activity of aucubin by inhibition of tumor necrosis factor-alpha production in RAW 264.7 cells. | 2004 | Planta Med. | pmid:15326552 |
| Wurst S et al. | Earthworms and litter distribution affect plant-defensive chemistry. | 2004 | J. Chem. Ecol. | pmid:15260217 |
| Biere A et al. | Plant chemical defense against herbivores and pathogens: generalized defense or trade-offs? | 2004 | Oecologia | pmid:15146326 |
| Peng MJ et al. | [Study on optimizing the analysis condition for active compound in Eucommia olive]. | 2004 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:15828353 |
| Fuchs A and Bowers MD | Patterns of iridoid glycoside production and induction in Plantago lanceolata and the importance of plant age. | 2004 | J. Chem. Ecol. | pmid:15586671 |
| Cimanga K et al. | Complement-inhibiting iridoids from Morinda morindoides. | 2003 | J. Nat. Prod. | pmid:12542353 |
| Chiang LC et al. | Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species. | 2003 | Planta Med. | pmid:12898413 |
| Chiang LC et al. | Antileukemic activity of selected natural products in Taiwan. | 2003 | Am. J. Chin. Med. | pmid:12723753 |
| Jeong HJ et al. | Inhibition of TNF-alpha and IL-6 production by Aucubin through blockade of NF-kappaB activation RBL-2H3 mast cells. | 2002 | Cytokine | pmid:12161100 |
| Tamura Y and Nishibe S | Changes in the concentrations of bioactive compounds in plantain leaves. | 2002 | J. Agric. Food Chem. | pmid:11958614 |
| Chiang LC et al. | Antiviral activity of Plantago major extracts and related compounds in vitro. | 2002 | Antiviral Res. | pmid:12076751 |
| Harput US et al. | Iridoid glucosides from Veronica hederifolia. | 2002 | Chem. Pharm. Bull. | pmid:12192146 |
| Harput US et al. | Phenylethanoid and iridoid glycosides from Veronica persica. | 2002 | Chem. Pharm. Bull. | pmid:12045353 |
| Lee DH et al. | Studies on the possible mechanisms of protective activity against alpha-amanitin poisoning by aucubin. | 2001 | Arch. Pharm. Res. | pmid:11235813 |
| Suomi J et al. | Determination of iridoid glycosides by micellar electrokinetic capillary chromatography-mass spectrometry with use of the partial filling technique. | 2001 | Electrophoresis | pmid:11519962 |
| Suomi J et al. | Extraction of iridoid glycosides and their determination by micellar electrokinetic capillary chromatography. | 2000 | J Chromatogr A | pmid:10677081 |
| Kim DH et al. | Mechanism of covalent adduct formation of aucubin to proteins. | 2000 | Toxicol. Lett. | pmid:10713483 |
| Chang IM | Liver-protective activities of aucubin derived from traditional oriental medicine. | 1998 | Res. Commun. Mol. Pathol. Pharmacol. | pmid:10100510 |
| Li Y et al. | The promoting effects of geniposidic acid and aucubin in Eucommia ulmoides Oliver leaves on collagen synthesis. | 1998 | Biol. Pharm. Bull. | pmid:9881644 |
| Bartholomaeus A and Ahokas J | Inhibition of P-450 by aucubin: is the biological activity of aucubin due to its glutaraldehyde-like aglycone? | 1995 | Toxicol. Lett. | pmid:7482595 |
| Ortiz de Urbina AV et al. | In vitro antispasmodic activity of peracetylated penstemonoside, aucubin and catalpol. | 1994 | Planta Med. | pmid:7809202 |
| Guo Y et al. | [Determination of aucubin in Plantago asiatica L., P. major L. and P. depressa Willd. by HPLC]. | 1991 | Zhongguo Zhong Yao Za Zhi | pmid:1811672 |
| Suh NJ et al. | Pharmacokinetic study of an iridoid glucoside: aucubin. | 1991 | Pharm. Res. | pmid:1924160 |
Aucubin
Aucubin is a lipid of Prenol Lipids (PR) class.
Cross Reference
