Aucubin

Aucubin is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 633 references associated with Aucubin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Lu R et al. Quantitation of catalpol in rat plasma by liquid chromatography/electrospray ionization tandem mass spectrometry and its pharmacokinetic study. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19744895
Cimanga K et al. Complement-inhibiting iridoids from Morinda morindoides. 2003 J. Nat. Prod. pmid:12542353
Rakotondramasy VC et al. Regioselective and stereospecific amination of iridoids: conversion of aucubin into aminoside antibiotic analogues. 2007 J. Nat. Prod. pmid:17253843
Chang LM et al. Aucubin: potential antidote for alpha-amanitin poisoning. 1984 J. Toxicol. Clin. Toxicol. pmid:6208374
Xue HY et al. Aucubin modulates Bcl-2 family proteins expression and inhibits caspases cascade in Hâ‚‚Oâ‚‚-induced PC12 cells. 2011 Mol. Biol. Rep. pmid:21120620
Xue HY et al. Neuroprotective properties of aucubin in diabetic rats and diabetic encephalopathy rats. 2012 Mol. Biol. Rep. pmid:22810648
Ramunno A et al. Taxonomical markers in two endemic plants of Sardinia: Verbascum conocarpum and Scrophularia trifoliata. 2006 Nat. Prod. Res. pmid:16644551
Venditti A et al. Phytochemical composition of polar fraction of Stachys germanica L. subsp. salviifolia (Ten.) Gams, a typical plant of Majella National Park. 2013 Nat. Prod. Res. pmid:22372659
Venditti A et al. Phytochemical analysis of Plantago sempervirens from Majella National Park. 2012 Nat. Prod. Res. pmid:22081901
Li J et al. Study of chemical composition and antimicrobial activity of leaves and roots of Scrophularia ningpoensis. 2009 Nat. Prod. Res. pmid:19418360
Ibrahim NA et al. Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruits growing in Egypt. 2008 Nat. Prod. Res. pmid:18415863
Sohn SH et al. The genome-wide expression profile of Scrophularia ningpoensis-treated thapsigargin-stimulated U-87MG cells. 2009 Neurotoxicology pmid:19442820
Zhang R et al. Antidiabetic activity of isoquercetin in diabetic KK -Ay mice. 2011 Nutr Metab (Lond) pmid:22133267
Bae JY et al. Protective actions of Rubus coreanus ethanol extract on collagenous extracellular matrix in ultraviolet-B irradiation-induced human dermal fibroblasts. 2007 Nutr Res Pract pmid:20368951
Biere A et al. Plant chemical defense against herbivores and pathogens: generalized defense or trade-offs? 2004 Oecologia pmid:15146326
Bennett AE et al. Arbuscular mycorrhizal fungal species suppress inducible plant responses and alter defensive strategies following herbivory. 2009 Oecologia pmid:19408016
Suh NJ et al. Pharmacokinetic study of an iridoid glucoside: aucubin. 1991 Pharm. Res. pmid:1924160
Liu Z et al. Simultaneous determination of four bioactive compounds in Verbena officinalis L. by using high-performance liquid chromatography. 2012 Pharmacogn Mag pmid:22701291
Gonda S et al. Effect of high relative humidity on dried Plantago lanceolata L. leaves during long-term storage: effects on chemical composition, colour and microbiological quality. 2012 Jan-Feb Phytochem Anal pmid:21618310
Kumar V et al. A proposed biosynthetic pathway of picrosides linked through the detection of biochemical intermediates in the endangered medicinal herb Picrorhiza kurroa. 2013 Nov-Dec Phytochem Anal pmid:23696248
Pankoke H et al. Role of plant β-glucosidases in the dual defense system of iridoid glycosides and their hydrolyzing enzymes in Plantago lanceolata and Plantago major. 2013 Phytochemistry pmid:23773298
Fleer H and Verspohl EJ Antispasmodic activity of an extract from Plantago lanceolata L. and some isolated compounds. 2007 Phytomedicine pmid:17298877
Xue HY et al. Aucubin prevents loss of hippocampal neurons and regulates antioxidative activity in diabetic encephalopathy rats. 2009 Phytother Res pmid:19140154
Háznagy-Radnai E et al. Antiinflammatory activities of Hungarian Stachys species and their iridoids. 2012 Phytother Res pmid:21887806
Xue HY et al. Protective effects of aucubin on Hâ‚‚Oâ‚‚-induced apoptosis in PC12 cells. 2012 Phytother Res pmid:21728203
Gálvez M et al. Antioxidant activity of Plantago bellardii All. 2005 Phytother Res pmid:16372378
Kirmizibekmez H et al. Antiprotozoal activity of Melampyrum arvense and its metabolites. 2011 Phytother Res pmid:20623589
Park KS and Chang IM Anti-inflammatory activity of aucubin by inhibition of tumor necrosis factor-alpha production in RAW 264.7 cells. 2004 Planta Med. pmid:15326552
Chiang LC et al. Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species. 2003 Planta Med. pmid:12898413
Ortiz de Urbina AV et al. In vitro antispasmodic activity of peracetylated penstemonoside, aucubin and catalpol. 1994 Planta Med. pmid:7809202
Mraja A et al. Plant community diversity influences allocation to direct chemical defence in Plantago lanceolata. 2011 PLoS ONE pmid:22174766
Lee HY et al. Eucommia ulmoides Oliver extract, aucubin, and geniposide enhance lysosomal activity to regulate ER stress and hepatic lipid accumulation. 2013 PLoS ONE pmid:24349058
Opitz SE et al. Host shifts from Lamiales to Brassicaceae in the sawfly genus Athalia. 2012 PLoS ONE pmid:22485146
Song WB et al. Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation. 2010 PLoS ONE pmid:20885979
Lee GH et al. Eucommia ulmoides cortex, geniposide and aucubin regulate lipotoxicity through the inhibition of lysosomal BAX. 2014 PLoS ONE pmid:24586300
Kim Y et al. Novel PI3K/Akt inhibitors screened by the cytoprotective function of human immunodeficiency virus type 1 Tat. 2011 PLoS ONE pmid:21765914
Chang IM Liver-protective activities of aucubin derived from traditional oriental medicine. 1998 Res. Commun. Mol. Pathol. Pharmacol. pmid:10100510
Xue H et al. Neuroprotection of aucubin in primary diabetic encephalopathy. 2008 Sci. China, C, Life Sci. pmid:18488169
Kim DH et al. Mechanism of covalent adduct formation of aucubin to proteins. 2000 Toxicol. Lett. pmid:10713483
Bartholomaeus A and Ahokas J Inhibition of P-450 by aucubin: is the biological activity of aucubin due to its glutaraldehyde-like aglycone? 1995 Toxicol. Lett. pmid:7482595
Jurisić R et al. Determination of aucubin and catalpol in Plantago species by micellar electrokinetic chromatography. 2004 Jan-Feb Z. Naturforsch., C, J. Biosci. pmid:15018047
Zhang Y et al. [Study on the chemical constituents of Buddleja purdomii]. 2005 Zhong Yao Cai pmid:16514886
Zheng J et al. [Enzymatic extraction and antibacterial activity of aucubin from Eucommia ulmoides leaves]. 2012 Zhong Yao Cai pmid:22822679
Yang R et al. [Hairy root culture optimization and aucubin medical composition production of Eucommia ulmoides]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19894530
Zhao XM et al. [Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction]. 2007 Zhongguo Zhong Yao Za Zhi pmid:18309665
Kang Z et al. [Research advances in pharmacology of aucubin and aucubigenin]. 2007 Zhongguo Zhong Yao Za Zhi pmid:18338591
Guo Y et al. [Determination of aucubin in Plantago asiatica L., P. major L. and P. depressa Willd. by HPLC]. 1991 Zhongguo Zhong Yao Za Zhi pmid:1811672