Gentiopicrin

Gentiopicrin is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 368 references associated with Gentiopicrin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
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Rojas A et al. Smooth muscle relaxing activity of gentiopicroside isolated from Gentiana spathacea. 2000 Planta Med. pmid:11199140
Oztürk N et al. Effects of Gentiana lutea ssp. symphyandra on the central nervous system in mice. 2002 Phytother Res pmid:12410542
Yang XF and Song CQ [Studies on the metabolism of gentiopicroside by rat intestinal flora]. 2000 Zhongguo Zhong Yao Za Zhi pmid:12525070
Kumarasamy Y et al. Bioactivity of gentiopicroside from the aerial parts of Centaurium erythraea. 2003 Fitoterapia pmid:12628413
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pmid:14381299
Zhao S et al. Separation and determination of gentiopicroside and swertiamarin in Tibetan medicines by micellar electrokinetic electrophoresis. 2004 Biomed. Chromatogr. pmid:14872543
Chen X et al. Simultaneous determination of some active ingredients in anti-viral preparations of traditional Chinese medicine by micellar electrokinetic chromatography. 2004 Biomed. Chromatogr. pmid:15386499
Wang XJ et al. [Influence of gentian leaf blight on the output and quality of Chinese gentian]. 2004 Zhongguo Zhong Yao Za Zhi pmid:15506279
Wang CH et al. Pharmacokinetics and tissue distribution of gentiopicroside following oral and intravenous administration in mice. 2004 Jul-Sep Eur J Drug Metab Pharmacokinet pmid:15537172
Ni H et al. [Determination and comparision of gentiopicroside of various parts of five species of genus Gentiana collected from Xinjiang by TLCS]. 2004 Zhong Yao Cai pmid:15551965
Wang C et al. [Determination of gentiopicroside in different morphological types of cultivated Gentiana manshurica population]. 2004 Zhongguo Zhong Yao Za Zhi pmid:15575198
Lin P et al. [Content determination of loganic acid and gentiopicroside in Tebitan herbal medicines Gentiana macrophylla and G. straminea by HPLC]. 2004 Zhong Yao Cai pmid:15810586
Oztürk N et al. Effects of gentiopicroside, sweroside and swertiamarine, secoiridoids from gentian (Gentiana lutea ssp. symphyandra), on cultured chicken embryonic fibroblasts. 2006 Planta Med. pmid:16557467
Tiwari RK et al. Genetic transformation of Gentiana macrophylla with Agrobacterium rhizogenes: growth and production of secoiridoid glucoside gentiopicroside in transformed hairy root cultures. 2007 Plant Cell Rep. pmid:16972092
Wang D et al. Biotransformation of gentiopicroside by asexual mycelia of Cordyceps sinensis. 2007 Bioorg. Med. Chem. Lett. pmid:17400449
Guarrera PM and Lucia LM Ethnobotanical remarks on Central and Southern Italy. 2007 J Ethnobiol Ethnomed pmid:17537240
Wang CH et al. Pharmacokinetics and bioavailability of gentiopicroside from decoctions of Gentianae and Longdan Xiegan Tang after oral administration in rats--comparison with gentiopicroside alone. 2007 J Pharm Biomed Anal pmid:17560062
Li WL et al. [Content of gentiopicroside and loganic acid in Radix gentianae and their fingerprints]. 2007 Yao Xue Xue Bao pmid:17703785
Zhang XQ et al. [Determination of three glycosides from herbs of Swertia punicea by RP-HPLC]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17802883
Wang CH et al. Pharmacokinetic behavior of gentiopicroside from decoction of Radix Gentianae, Gentiana macrophylla after oral administration in rats: a pharmacokinetic comaprison with gentiopicroside after oral and intravenous administration alone. 2007 Arch. Pharm. Res. pmid:17958334
Zhang JS et al. [Simultaneous determination of five bitter secoiridoid glycosides in nine Chinese Gentiana species used as the Chinese drug "long dan" by high performance liquid chromatography]. 1991 Yao Xue Xue Bao pmid:1823982
Xu YW et al. [Preparative separation of gentiopicrin from Radix Gentianae by high-speed counter-current chromatography with macroporous resin]. 2007 Zhongguo Zhong Yao Za Zhi pmid:18338594
Chen L et al. Down-regulation of NR2B receptors partially contributes to analgesic effects of Gentiopicroside in persistent inflammatory pain. 2008 Neuropharmacology pmid:18410946
Zhao Y et al. [Enrichment process of gentiopicroside from the leaves of Gentiana macropylla with macroporous resin]. 2007 Zhong Yao Cai pmid:18422193
Jonville MC et al. Fagraldehyde, a secoiridoid isolated from Fagraea fragrans. 2008 J. Nat. Prod. pmid:19053508
Yin H et al. Gentiopicrin-producing endophytic fungus isolated from Gentiana macrophylla. 2009 Phytomedicine pmid:19200701
Chen LY et al. Changes of gentiopicroside synthesis during somatic embryogenesis in Gentiana macrophylla. 2009 Planta Med. pmid:19548190
He X et al. Sensitive determination of gentiopicroside in medicine and bio-fluids using luminol-myoglobin chemiluminescence combined with flow injection technique. 2010 Sep-Oct Luminescence pmid:19743525
Xu K et al. [Determination of six active components in three species of genus Swertia by HPLC multiwavelength with detection]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19771868
Mustafayeva K et al. DNA-damaging, mutagenic, and clastogenic activities of gentiopicroside isolated from Cephalaria kotschyi roots. 2010 J. Nat. Prod. pmid:20055434
Lian LH et al. Anti-apoptotic activity of gentiopicroside in D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure. 2010 Chem. Biol. Interact. pmid:20558151
Siler B et al. Antibacterial and antifungal screening of Centaurium pulchellum crude extracts and main secoiridoid compounds. 2010 Nat Prod Commun pmid:21121240
Lei Y et al. [Preparation of gentiopicroside from the extract of Swertia mussotii Franch by preparative high performance liquid chromatography]. 2010 Se Pu pmid:21171291
Liang X et al. Effect of Feining on bleomycin-induced pulmonary injuries in rats. 2011 J Ethnopharmacol pmid:21333727
Wang J et al. Introgression of Swertia mussotii gene into Bupleurum scorzonerifolium via somatic hybridization. 2011 BMC Plant Biol. pmid:21513581
Li HL et al. Development and validation of a LC-ESI-MS/MS method for the determination of swertiamarin in rat plasma and its application in pharmacokinetics. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21531636
Wei S et al. Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus-induced superoxide generation, phosphorylation and translocation of cytosolic compounds to plasma membrane in human neutrophils. 2012 Phytother Res pmid:21584870
Wu YH et al. [Study on the quality and genetic diversity of Gentiana macrophylla pall of different habitats]. 2011 Zhong Yao Cai pmid:21809537
Chang-Liao WL et al. Isolation of gentiopicroside from Gentianae Radix and its pharmacokinetics on liver ischemia/reperfusion rats. 2012 J Ethnopharmacol pmid:21855624
Jiang L et al. Introgression of the heterologous nuclear DNAs and efficacious compositions from Swertia tetraptera Maxim. into Bupleurum scorzonerifolium Willd. via somatic hybridization. 2012 Protoplasma pmid:21956131
Dou JJ et al. [Transdermal delivery of Gentiana macrophylla complex components system under micro-needle conditions]. 2011 Yao Xue Xue Bao pmid:22121788
Yan Z et al. Potent Antifungal Activity of Pure Compounds from Traditional Chinese Medicine Extracts against Six Oral Candida Species and the Synergy with Fluconazole against Azole-Resistant Candida albicans. 2012 Evid Based Complement Alternat Med pmid:22454653
Liu SB et al. Gentiopicroside attenuates morphine rewarding effect through downregulation of GluN2B receptors in nucleus accumbens. 2012 CNS Neurosci Ther pmid:22621711
Song B et al. [Quickly investigating the absorption ingredients of Gentianae Radix et Rhizoma by SEMAC]. 2012 Zhongguo Zhong Yao Za Zhi pmid:22792800
Mihailović V et al. Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in rats. 2013 Food Chem. Toxicol. pmid:23146698
Hou Q et al. [Callus cultivation and determination of gentiopicroside from Gentiana macrophylla]. 2012 Zhong Yao Cai pmid:23213725
Yang Y et al. [Determination and quality assessment of 10 ingredients gentiopicroside and sweroside and so on in Tibetan medicine Jia Di (Swertia chirayita)]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23311169
Deng Y et al. In vitro inhibition and induction of human liver cytochrome P450 enzymes by gentiopicroside: potent effect on CYP2A6. 2013 Drug Metab. Pharmacokinet. pmid:23419353