Gentiopicrin

Gentiopicrin is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 368 references associated with Gentiopicrin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Chen C et al. Gentiopicroside ameliorates bleomycin-induced pulmonary fibrosis in mice via inhibiting inflammatory and fibrotic process. 2018 Biochem. Biophys. Res. Commun. pmid:29278701
Tang X et al. Target profiling analyses of bile acids in the evaluation of hepatoprotective effect of gentiopicroside on ANIT-induced cholestatic liver injury in mice. 2016 J Ethnopharmacol pmid:27582267
Amakura Y et al. Chromatographic Evaluation and Characterization of Components of Gentian Root Extract Used as Food Additives. 2016 Chem. Pharm. Bull. pmid:26726749
Cao X et al. Transcriptional Responses and Gentiopicroside Biosynthesis in Methyl Jasmonate-Treated Gentiana macrophylla Seedlings. 2016 PLoS ONE pmid:27851826
Zhao L et al. Gentiopicroside prevents interleukin-1 beta induced inflammation response in rat articular chondrocyte. 2015 J Ethnopharmacol pmid:26116164
Zhang X et al. De Novo Assembly and Characterization of the Transcriptome of the Chinese Medicinal Herb, Gentiana rigescens. 2015 Int J Mol Sci pmid:26006235
Fan G et al. Metabolic discrimination of Swertia mussotii and Swertia chirayita known as "Zangyinchen" in traditional Tibetan medicine by (1)H NMR-based metabolomics. 2014 J Pharm Biomed Anal pmid:24992216
Lu CM et al. Determination and pharmacokinetic study of gentiopicroside, geniposide, baicalin, and swertiamarin in Chinese herbal formulae after oral administration in rats by LC-MS/MS. 2014 Molecules pmid:25532849
Yang H et al. Spatial variation profiling of four phytochemical constituents in Gentiana straminea (Gentianaceae). 2014 J Nat Med pmid:23604973
Zeng WL et al. Microbial biotransformation of gentiopicroside by the endophytic fungus Penicillium crustosum 2T01Y01. 2014 Appl. Environ. Microbiol. pmid:24141132
Han H et al. Combination of UHPLC/Q-TOF-MS, NMR spectroscopy, and ECD calculation for screening and identification of reactive metabolites of gentiopicroside in humans. 2014 Anal Bioanal Chem pmid:24408300
Zeng Y et al. [Optimum harvest study of Gentiana crassicaulis in Ludian]. 2014 Zhongguo Zhong Yao Za Zhi pmid:25272487
Wang Z et al. New analytical method for the study of the metabolism of gentiopicroside in rats after oral administration by LC-TOF-MS following picolinoyl derivatization. 2014 J Sep Sci pmid:24376019
Tanaka R et al. Application of quantitative 1H-NMR method to determination of gentiopicroside in Gentianae radix and Gentianae scabrae radix. 2014 J Nat Med pmid:24687868
Wani BA et al. Induction of apoptosis in human pancreatic MiaPaCa-2 cells through the loss of mitochondrial membrane potential (ΔΨm) by Gentiana kurroo root extract and LC-ESI-MS analysis of its principal constituents. 2013 Phytomedicine pmid:23453831
Mihailović V et al. Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in rats. 2013 Food Chem. Toxicol. pmid:23146698
Zeng W et al. Identification of bio-active metabolites of gentiopicroside by UPLC/Q-TOF MS and NMR. 2013 Biomed. Chromatogr. pmid:23733682
Deng Y et al. In vitro inhibition and induction of human liver cytochrome P450 enzymes by gentiopicroside: potent effect on CYP2A6. 2013 Drug Metab. Pharmacokinet. pmid:23419353
Zhang K et al. Preparation, characterization, and in vivo pharmacokinetics of nanostructured lipid carriers loaded with oleanolic acid and gentiopicrin. 2013 Int J Nanomedicine pmid:24009420
Li YL et al. [Simultaneous determination of five constituents in eight Qingyedan species derived from Swertia plants by HPLC]. 2013 Zhongguo Zhong Yao Za Zhi pmid:23944076
Suyama Y et al. Rigenolide A, a new secoiridoid glucoside with a cyclobutane skeleton, and three new acylated secoiridoid glucosides from Gentiana rigescens Franch. 2013 Fitoterapia pmid:23994629
Liang J et al. Rapid preparative separation of six bioactive compounds from Gentiana crassicaulis Duthie ex Burk. using microwave-assisted extraction coupled with high-speed counter-current chromatography. 2013 J Sep Sci pmid:24151213
Feng B et al. [Comparative study on pharmacokinetics of gentiopicroside and gentianae radix extract in rats]. 2013 Zhong Yao Cai pmid:24218974
Yan Z et al. Potent Antifungal Activity of Pure Compounds from Traditional Chinese Medicine Extracts against Six Oral Candida Species and the Synergy with Fluconazole against Azole-Resistant Candida albicans. 2012 Evid Based Complement Alternat Med pmid:22454653
Wei S et al. Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus-induced superoxide generation, phosphorylation and translocation of cytosolic compounds to plasma membrane in human neutrophils. 2012 Phytother Res pmid:21584870
Chang-Liao WL et al. Isolation of gentiopicroside from Gentianae Radix and its pharmacokinetics on liver ischemia/reperfusion rats. 2012 J Ethnopharmacol pmid:21855624
Liu SB et al. Gentiopicroside attenuates morphine rewarding effect through downregulation of GluN2B receptors in nucleus accumbens. 2012 CNS Neurosci Ther pmid:22621711
Jiang L et al. Introgression of the heterologous nuclear DNAs and efficacious compositions from Swertia tetraptera Maxim. into Bupleurum scorzonerifolium Willd. via somatic hybridization. 2012 Protoplasma pmid:21956131
Song B et al. [Quickly investigating the absorption ingredients of Gentianae Radix et Rhizoma by SEMAC]. 2012 Zhongguo Zhong Yao Za Zhi pmid:22792800
Hou Q et al. [Callus cultivation and determination of gentiopicroside from Gentiana macrophylla]. 2012 Zhong Yao Cai pmid:23213725
Yang Y et al. [Determination and quality assessment of 10 ingredients gentiopicroside and sweroside and so on in Tibetan medicine Jia Di (Swertia chirayita)]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23311169
Wang J et al. Introgression of Swertia mussotii gene into Bupleurum scorzonerifolium via somatic hybridization. 2011 BMC Plant Biol. pmid:21513581
Li HL et al. Development and validation of a LC-ESI-MS/MS method for the determination of swertiamarin in rat plasma and its application in pharmacokinetics. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21531636
Dou JJ et al. [Transdermal delivery of Gentiana macrophylla complex components system under micro-needle conditions]. 2011 Yao Xue Xue Bao pmid:22121788
Wu YH et al. [Study on the quality and genetic diversity of Gentiana macrophylla pall of different habitats]. 2011 Zhong Yao Cai pmid:21809537
Liang X et al. Effect of Feining on bleomycin-induced pulmonary injuries in rats. 2011 J Ethnopharmacol pmid:21333727
He X et al. Sensitive determination of gentiopicroside in medicine and bio-fluids using luminol-myoglobin chemiluminescence combined with flow injection technique. 2010 Sep-Oct Luminescence pmid:19743525
Siler B et al. Antibacterial and antifungal screening of Centaurium pulchellum crude extracts and main secoiridoid compounds. 2010 Nat Prod Commun pmid:21121240
Lei Y et al. [Preparation of gentiopicroside from the extract of Swertia mussotii Franch by preparative high performance liquid chromatography]. 2010 Se Pu pmid:21171291
Lian LH et al. Anti-apoptotic activity of gentiopicroside in D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure. 2010 Chem. Biol. Interact. pmid:20558151
Mustafayeva K et al. DNA-damaging, mutagenic, and clastogenic activities of gentiopicroside isolated from Cephalaria kotschyi roots. 2010 J. Nat. Prod. pmid:20055434
Yin H et al. Gentiopicrin-producing endophytic fungus isolated from Gentiana macrophylla. 2009 Phytomedicine pmid:19200701
Xu K et al. [Determination of six active components in three species of genus Swertia by HPLC multiwavelength with detection]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19771868
Chen LY et al. Changes of gentiopicroside synthesis during somatic embryogenesis in Gentiana macrophylla. 2009 Planta Med. pmid:19548190
Jonville MC et al. Fagraldehyde, a secoiridoid isolated from Fagraea fragrans. 2008 J. Nat. Prod. pmid:19053508
Chen L et al. Down-regulation of NR2B receptors partially contributes to analgesic effects of Gentiopicroside in persistent inflammatory pain. 2008 Neuropharmacology pmid:18410946
Wang CH et al. Pharmacokinetics and bioavailability of gentiopicroside from decoctions of Gentianae and Longdan Xiegan Tang after oral administration in rats--comparison with gentiopicroside alone. 2007 J Pharm Biomed Anal pmid:17560062
Wang CH et al. Pharmacokinetic behavior of gentiopicroside from decoction of Radix Gentianae, Gentiana macrophylla after oral administration in rats: a pharmacokinetic comaprison with gentiopicroside after oral and intravenous administration alone. 2007 Arch. Pharm. Res. pmid:17958334
Wang D et al. Biotransformation of gentiopicroside by asexual mycelia of Cordyceps sinensis. 2007 Bioorg. Med. Chem. Lett. pmid:17400449
Li WL et al. [Content of gentiopicroside and loganic acid in Radix gentianae and their fingerprints]. 2007 Yao Xue Xue Bao pmid:17703785