| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| GarcÃa D et al. | Antiinflammatory effects of different extracts and harpagoside isolated from Scrophularia frutescens L. | 1996 | Farmaco | pmid:8766229 |
| Mestdagh O and Torck M | [Quality evaluation of Harpagophyton capsules]. | 1995 | Ann Pharm Fr | pmid:7677395 |
| Fontaine J et al. | [Biological analysis of Harpagophytum procumbens D.C. II. Pharmacological analysis of the effects of harpagoside, harpagide and harpagogenine on the isolated guinea-pig ileum (author's transl)]. | 1981 Sep-Oct | J Pharm Belg | pmid:7310625 |
| Circosta C et al. | A drug used in traditional medicine: Harpagophytum procumbens DC. II. Cardiovascular activity. | 1984 | J Ethnopharmacol | pmid:6482477 |
| Occhiuto F et al. | A drug used in traditional medicine: Harpagophytum procumbens DC. IV. Effects on some isolated muscle preparations. | 1985 | J Ethnopharmacol | pmid:4021517 |
| Costa De Pasquale R et al. | A drug used in traditional medicine: Harpagophytum procumbens DC. III. Effects on hyperkinetic ventricular arrhythmias by reperfusion. | 1985 | J Ethnopharmacol | pmid:4021516 |
| pmid:28635142 | ||||
| Locatelli M et al. | Optimization of Aqueous Extraction and Biological Activity of Harpagophytum procumbens Root on Ex Vivo Rat Colon Inflammatory Model. | 2017 | Phytother Res | pmid:28447368 |
| pmid:28106392 | ||||
| pmid:27991703 | ||||
| pmid:27082319 | ||||
| pmid:26979254 | ||||
| Sheu SY et al. | Radix Scrophulariae extracts (harpagoside) suppresses hypoxia-induced microglial activation and neurotoxicity. | 2015 | BMC Complement Altern Med | pmid:26370415 |
| pmid:26308264 | ||||
| pmid:26135675 | ||||
| pmid:26049170 | ||||
| pmid:25431110 | ||||
| pmid:25175765 | ||||
| pmid:25041697 | ||||
| pmid:24735384 | ||||
| Georgiev MI et al. | Harpagoside: from Kalahari Desert to pharmacy shelf. | 2013 | Phytochemistry | pmid:23642455 |
| Zhou W et al. | [HPLC fingerprint of scrophulariae radix from southwest China]. | 2012 | Zhong Yao Cai | pmid:23320352 |
| Tian J et al. | Preparative isolation and purification of harpagoside and angroside C from the root of Scrophularia ningpoensis Hemsley by high-speed counter-current chromatography. | 2012 | J Sep Sci | pmid:23001886 |
| Boeckenholt C et al. | Effect of silymarin and harpagoside on inflammation reaction of BEAS-2B cells, on ciliary beat frequency (CBF) of trachea explants and on mucociliary clearance (MCC). | 2012 | Planta Med. | pmid:22411727 |
| Bai Y et al. | [Determination of harpagide and harpagoside in Scrophulariae Radix by HPLC-UV]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22242433 |
| Sun X et al. | Harpagoside attenuates MPTP/MPP⺠induced dopaminergic neurodegeneration and movement disorder via elevating glial cell line-derived neurotrophic factor. | 2012 | J. Neurochem. | pmid:22192054 |
| Háznagy-Radnai E et al. | Antiinflammatory activities of Hungarian Stachys species and their iridoids. | 2012 | Phytother Res | pmid:21887806 |
| Georgiev MI et al. | Metabolic differentiations and classification of Verbascum species by NMR-based metabolomics. | 2011 | Phytochemistry | pmid:21807390 |
| Zhang L et al. | Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro. | 2011 | Bioorg. Med. Chem. | pmid:21775152 |
| Modarai M et al. | The interaction potential of herbal medicinal products: a luminescence-based screening platform assessing effects on cytochrome P450 and its use with devil's claw (Harpagophyti radix) preparations. | 2011 | J. Pharm. Pharmacol. | pmid:21749392 |
| Zhang X et al. | [Simultaneous determination of five constituents in Scrophularia ningpoensis by HPLC]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:21710734 |
| Yang S et al. | Harpagoside variation is positively correlated with temperature in Scrophularia ningpoensis Hemsl. | 2011 | J. Agric. Food Chem. | pmid:21322564 |
| Anauate MC et al. | Effect of isolated fractions of Harpagophytum procumbens D.C. (devil's claw) on COX-1, COX-2 activity and nitric oxide production on whole-blood assay. | 2010 | Phytother Res | pmid:20812280 |
| Takeda Y et al. | Morroniside cinnamic acid conjugate as an anti-inflammatory agent. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20621474 |
| Inaba K et al. | Inhibitory effects of devil's claw (secondary root of Harpagophytum procumbens) extract and harpagoside on cytokine production in mouse macrophages. | 2010 | J Nat Med | pmid:20177800 |
| Ouitas NA and Heard C | Estimation of the relative antiinflammatory efficacies of six commercial preparations of Harpagophytum procumbens (Devil's Claw). | 2010 | Phytother Res | pmid:19610038 |
| Romiti N et al. | Effects of Devil's Claw (Harpagophytum procumbens) on the multidrug transporter ABCB1/P-glycoprotein. | 2009 | Phytomedicine | pmid:19577448 |
| Li J et al. | Study of chemical composition and antimicrobial activity of leaves and roots of Scrophularia ningpoensis. | 2009 | Nat. Prod. Res. | pmid:19418360 |
| Niu Z et al. | [Study on preparation and quantity determination of Scrophularia ningpoensis dispensing granules]. | 2009 | Zhongguo Zhong Yao Za Zhi | pmid:19382447 |
| Wu Q et al. | An in vivo microdialysis measurement of harpagoside in rat blood and bile for predicting hepatobiliary excretion and its interaction with cyclosporin A and verapamil. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19237327 |
| Wagner S et al. | Validated HPTLC methods for the determination of salicin in Salix sp. and of harpagoside in Harpagophytum [corrected] procumbens. | 2008 | J Pharm Biomed Anal | pmid:18602786 |
| Jeong EJ et al. | Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice. | 2008 | Eur. J. Pharmacol. | pmid:18462717 |
| Abdelouahab N and Heard C | Effect of the major glycosides of Harpagophytum procumbens (Devil's Claw) on epidermal cyclooxygenase-2 (COX-2) in vitro. | 2008 | J. Nat. Prod. | pmid:18412394 |
| Colas C et al. | Optimization of solid-phase extraction for the liquid chromatography-mass spectrometry analysis of harpagoside, 8-para-coumaroyl harpagide, and harpagide in equine plasma and urine. | 2008 | J Chromatogr Sci | pmid:18366880 |
| Li P et al. | Simultaneous determination of harpagoside and cinnamic acid in rat plasma by high-performance liquid chromatography: application to a pharmacokinetic study. | 2007 | Anal Bioanal Chem | pmid:17899026 |
| Wang SJ et al. | Simultaneous determination of harpagoside and cinnamic acid in rat plasma by liquid chromatography electrospray ionization mass spectrometry and its application to pharmacokinetic studies. | 2008 | Biomed. Chromatogr. | pmid:17853386 |
| Tong S et al. | Preparative isolation and purification of harpagoside from Scrophularia ningpoensis hemsley by high-speed counter-current chromatography. | 2006 Nov-Dec | Phytochem Anal | pmid:17144248 |
| Colas C et al. | Liquid chromatography/electrospray ionization mass spectrometric characterization of Harpagophytum in equine urine and plasma. | 2006 | Rapid Commun. Mass Spectrom. | pmid:17044124 |
| Günther M et al. | High anti-inflammatory activity of harpagoside-enriched extracts obtained from solvent-modified super- and subcritical carbon dioxide extractions of the roots of Harpagophytum procumbens. | 2006 Jan-Feb | Phytochem Anal | pmid:16454469 |
| Huang TH et al. | Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-kappa B activation. | 2006 | J Ethnopharmacol | pmid:16203115 |
Harpagoside
Harpagoside is a lipid of Prenol Lipids (PR) class.
Cross Reference
