(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Uveitis, Posterior D015866 5 associated lipids
Endophthalmitis D009877 12 associated lipids
Pain D010146 64 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Acharya SA et al. Hydrogel-stabilized droplet bilayers for high speed solution exchange. 2013 Sci Rep pmid:24190577
Kong G et al. Menthol cigarette and marijuana use among adolescents. 2013 Nicotine Tob. Res. pmid:23884319
Ali MS et al. In vitro antioxidant, cytotoxic, thrombolytic activities and phytochemical evaluation of methanol extract of the A. philippense L. leaves. 2013 Asian Pac J Trop Biomed pmid:23730559
Reitzel LR et al. Race moderates the effect of menthol cigarette use on short-term smoking abstinence. 2013 Nicotine Tob. Res. pmid:23288873
Rajput SB and Karuppayil SM Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans. 2013 Springerplus pmid:23449869
Smith AP and Boden C Effects of chewing menthol gum on the alertness of healthy volunteers and those with an upper respiratory tract illness. 2013 Stress Health pmid:22674677
Radu CD et al. Cotton-made cellulose support for anti-allergic pajamas. 2013 Carbohydr Polym pmid:23618296
Villanti AC et al. Flavored tobacco product use among U.S. young adults. 2013 Am J Prev Med pmid:23498105
Liu XR et al. Down-regulation of TRPM8 in pulmonary arteries of pulmonary hypertensive rats. 2013 Cell. Physiol. Biochem. pmid:23817166
Ngo-Thi MT et al. Enantioselective hydrolysis of dl-menthyl benzoate by cell-free extract of newly isolated Acinetobacter sp. ECU2040. 2013 Appl. Biochem. Biotechnol. pmid:23801098
Vahabi B et al. TRPM8 agonists modulate contraction of the pig urinary bladder. 2013 Can. J. Physiol. Pharmacol. pmid:23826977
Selescu T et al. Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin. 2013 Chem. Senses pmid:23828908
Kurose M and Meng ID Dry eye modifies the thermal and menthol responses in rat corneal primary afferent cool cells. 2013 J. Neurophysiol. pmid:23636717
Plevkova J et al. The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol. 2013 J. Appl. Physiol. pmid:23640596
Kurohane K et al. Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice. 2013 Toxicol. Lett. pmid:23296101
Bharti N et al. The greater effectiveness of Glomus mosseae and Glomus intraradices in improving productivity, oil content and tolerance of salt-stressed menthol mint (Mentha arvensis). 2013 J. Sci. Food Agric. pmid:23288591
Jones MR et al. Menthol cigarettes, race/ethnicity, and biomarkers of tobacco use in U.S. adults: the 1999-2010 National Health and Nutrition Examination Survey (NHANES). 2013 Cancer Epidemiol. Biomarkers Prev. pmid:23250935
Kolassa N Menthol differs from other terpenic essential oil constituents. 2013 Regul. Toxicol. Pharmacol. pmid:23207345
Jones MR et al. Smoking, menthol cigarettes, and peripheral artery disease in U.S. adults. 2013 Nicotine Tob. Res. pmid:23212436
Maji D et al. A natural plant growth promoter calliterpenone from a plant Callicarpa macrophylla Vahl improves the plant growth promoting effects of plant growth promoting rhizobacteria (PGPRs). 2013 World J. Microbiol. Biotechnol. pmid:23271460
Carter L Commentary on Nonnemaker et al. (2013): Banning menthol cigarettes - is it time to conduct the experiment? 2013 Addiction pmid:23279359
Abdullah GZ et al. Carbopol 934, 940 and Ultrez 10 as viscosity modifiers of palm olein esters based nano-scaled emulsion containing ibuprofen. 2013 Pak J Pharm Sci pmid:23261730
Kashima H and Hayashi N Facial skin blood flow responses to irritant stimuli in the oral cavity. 2013 Auton Neurosci pmid:23265982
Journigan VB and Zaveri NT TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology. 2013 Life Sci. pmid:23159643
Averbeck B et al. Thermal grill-evoked sensations of heat correlate with cold pain threshold and are enhanced by menthol and cinnamaldehyde. 2013 Eur J Pain pmid:23138876
Wilson MD et al. Efficacy of DEET and non-DEET-based insect repellents against bites of Simulium damnosum vectors of onchocerciasis. 2013 Med. Vet. Entomol. pmid:23167529
Brody AL et al. Up-regulation of nicotinic acetylcholine receptors in menthol cigarette smokers. 2013 Int. J. Neuropsychopharmacol. pmid:23171716
Villanti AC et al. Menthol cigarettes and mortality: keeping focus on the public health standard. 2013 Nicotine Tob. Res. pmid:22990220
Farco JA and Grundmann O Menthol--pharmacology of an important naturally medicinal "cool". 2013 Mini Rev Med Chem pmid:23061635
Motilal S and Maharaj RG Nutmeg extracts for painful diabetic neuropathy: a randomized, double-blind, controlled study. 2013 J Altern Complement Med pmid:23098698
Lachenmeier DW et al. What happens if people start drinking mouthwash as surrogate alcohol? A quantitative risk assessment. 2013 Food Chem. Toxicol. pmid:23041419
Bose SK et al. Effect of gibberellic acid and calliterpenone on plant growth attributes, trichomes, essential oil biosynthesis and pathway gene expression in differential manner in Mentha arvensis L. 2013 Plant Physiol. Biochem. pmid:23514759
Zuo X et al. Operant behavioral responses to orofacial cold stimuli in rats with chronic constrictive trigeminal nerve injury: effects of menthol and capsazepine. 2013 Mol Pain pmid:23767981
Moreland-Russell S et al. Disparities and menthol marketing: additional evidence in support of point of sale policies. 2013 Int J Environ Res Public Health pmid:24071922
Kamatou GP et al. Menthol: a simple monoterpene with remarkable biological properties. 2013 Phytochemistry pmid:24054028
Alpizar YA et al. Lack of correlation between the amplitudes of TRP channel-mediated responses to weak and strong stimuli in intracellular Ca(2+) imaging experiments. 2013 Cell Calcium pmid:24079971
Amato A et al. Tetrodotoxin-dependent effects of menthol on mouse gastric motor function. 2013 Eur. J. Pharmacol. pmid:24041922
Tang Z et al. Pirt functions as an endogenous regulator of TRPM8. 2013 Nat Commun pmid:23863968
Rozza AL et al. Effect of menthol in experimentally induced ulcers: pathways of gastroprotection. 2013 Chem. Biol. Interact. pmid:24121185
Ostacolo C et al. Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists. 2013 Eur J Med Chem pmid:24095758
Vetter I et al. Amplified cold transduction in native nociceptors by M-channel inhibition. 2013 J. Neurosci. pmid:24133266
Nuisin R et al. Microencapsulation of menthol by crosslinked chitosan via porous glass membrane emulsification technique and their controlled release properties. 2013 J Microencapsul pmid:23398357
Flores-Rizo JO et al. 8-Alkoxy- and 8-aryloxy-BODIPYs: straightforward fluorescent tagging of alcohols and phenols. 2013 J. Org. Chem. pmid:23721096
Liu B et al. TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain. 2013 Pain pmid:23820004
Li S et al. Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cells. 2013 Bioorg. Med. Chem. Lett. pmid:24210499
Tsumura M et al. Functional expression of TRPM8 and TRPA1 channels in rat odontoblasts. 2013 PLoS ONE pmid:24358160
Barkin RL The pharmacology of topical analgesics. 2013 Postgrad Med pmid:24547599
Ashoor A et al. Menthol inhibits 5-HT3 receptor-mediated currents. 2013 J. Pharmacol. Exp. Ther. pmid:23965380
Winhusen TM et al. A tale of two stimulants: mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence. 2013 Drug Alcohol Depend pmid:24075226
Sharara AI et al. Sugar-free menthol candy drops improve the palatability and bowel cleansing effect of polyethylene glycol electrolyte solution. 2013 Gastrointest. Endosc. pmid:23769143