(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Endophthalmitis D009877 12 associated lipids
Pain D010146 64 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Kang W et al. Characterization of aroma compounds in Chinese bayberry (Myrica rubra Sieb. et Zucc.) by gas chromatography mass spectrometry (GC-MS) and olfactometry (GC-O). 2012 J. Food Sci. pmid:23009608
DiFranza JR Research opportunities concerning youth and the Family Smoking Prevention and Tobacco Control Act. 2012 Nicotine Tob. Res. pmid:21975309
Okamoto Y et al. Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines. 2012 Int. J. Oncol. pmid:22267123
Wu X et al. Mucoadhesive fenretinide patches for site-specific chemoprevention of oral cancer: enhancement of oral mucosal permeation of fenretinide by coincorporation of propylene glycol and menthol. 2012 Mol. Pharm. pmid:22280430
Hans M et al. Menthol suppresses nicotinic acetylcholine receptor functioning in sensory neurons via allosteric modulation. 2012 Chem. Senses pmid:22281529
Bhadania M et al. Protective effect of menthol on β-amyloid peptide induced cognitive deficits in mice. 2012 Eur. J. Pharmacol. pmid:22329901
Okuyemi KS et al. Effects of menthol on the pharmacokinetics of bupropion among Black smokers. 2012 Nicotine Tob. Res. pmid:22318754
Abobo CV et al. Effect of menthol on nicotine pharmacokinetics in rats after cigarette smoke inhalation. 2012 Nicotine Tob. Res. pmid:22311961
Taylor R et al. A randomized, double-blind comparison shows the addition of oxygenated glycerol triesters to topical mentholated cream for the treatment of acute musculoskeletal pain demonstrates incremental benefit over time. 2012 Pain Pract pmid:22304620
Yilmaz HG and Bayindir H Clinical evaluation of chlorhexidine and essential oils for adjunctive effects in ultrasonic instrumentation of furcation involvements: a randomized controlled clinical trial. 2012 Int J Dent Hyg pmid:22212113
Park HE et al. Simple preparative gas chromatographic method for isolation of menthol and menthone from peppermint oil, with quantitative GC-MS and (1) H NMR assay. 2012 J Sep Sci pmid:22213698
Maeda H et al. A dual catalyst system provides the shortest pathway for L-menthol synthesis. 2012 Chem. Commun. (Camb.) pmid:22218824
Teichert RW et al. Characterization of two neuronal subclasses through constellation pharmacology. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22778416
Wise PM et al. Sweet taste and menthol increase cough reflex thresholds. 2012 Pulm Pharmacol Ther pmid:22465565
O'Connor RJ et al. What would menthol smokers do if menthol in cigarettes were banned? Behavioral intentions and simulated demand. 2012 Addiction pmid:22471735
Henriksen L et al. Targeted advertising, promotion, and price for menthol cigarettes in California high school neighborhoods. 2012 Nicotine Tob. Res. pmid:21705460
Segev D et al. Chemical and morphological diversity in wild populations of Mentha longifolia in Israel. 2012 Chem. Biodivers. pmid:22422525
Klasen K et al. The TRPM8 ion channel comprises direct Gq protein-activating capacity. 2012 Pflugers Arch. pmid:22460725
Ceacero-Vega AA et al. Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl). 2012 J Phys Chem A pmid:22448964
Kramlinger VM et al. Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol. 2012 Chem. Biol. Interact. pmid:22486895
Muscat JE et al. Menthol smoking in relation to time to first cigarette and cotinine: results from a community-based study. 2012 Regul. Toxicol. Pharmacol. pmid:22487419
Vozoris NT Mentholated cigarettes and cardiovascular and pulmonary diseases: a population-based study. 2012 Arch. Intern. Med. pmid:22493467
Renner B and Schreiber K Olfactory and trigeminal interaction of menthol and nicotine in humans. 2012 Exp Brain Res pmid:22434343
Wang Y et al. Menthol inhibits the proliferation and motility of prostate cancer DU145 cells. 2012 Pathol. Oncol. Res. pmid:22437241
Mohanta TK et al. Ginkgo biloba responds to herbivory by activating early signaling and direct defenses. 2012 PLoS ONE pmid:22448229
Kabat GC et al. Mentholated cigarettes and smoking-related cancers revisited: an ecologic examination. 2012 Regul. Toxicol. Pharmacol. pmid:22429780
Bharate SS and Bharate SB Modulation of thermoreceptor TRPM8 by cooling compounds. 2012 ACS Chem Neurosci pmid:22860192
Jiao HY et al. [GC-MS study on fingerprint of volatile oil from Kadsura heteroclita]. 2012 Zhong Yao Cai pmid:23451498
Kono T et al. Oxaliplatin-induced neurotoxicity involves TRPM8 in the mechanism of acute hypersensitivity to cold sensation. 2012 Brain Behav pmid:22574275
Takaishi M et al. 1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1. 2012 Mol Pain pmid:23192000
McCoy ES et al. CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch. 2012 PLoS ONE pmid:22563493
Tanabe A et al. Effects of corticotropin-releasing factor on intermediolateral cell column neurons of newborn rats. 2012 Auton Neurosci pmid:23151516
Sherkheli MA et al. Supercooling agent icilin blocks a warmth-sensing ion channel TRPV3. 2012 ScientificWorldJournal pmid:22548000
Kataoka H and Ueno S Nightmare-enacting behavior responding to zonisamide in early Parkinson's disease. 2012 Case Rep Neurol pmid:22545035
Kim A et al. Defects in the peripheral taste structure and function in the MRL/lpr mouse model of autoimmune disease. 2012 PLoS ONE pmid:22536412
Camele I et al. In vitro control of post-harvest fruit rot fungi by some plant essential oil components. 2012 Int J Mol Sci pmid:22408454
Martini C et al. Pharmacodynamic analysis of the analgesic effect of capsaicin 8% patch (Qutenzaâ„¢) in diabetic neuropathic pain patients: detection of distinct response groups. 2012 J Pain Res pmid:22536092
Umezu T Unusual effects of nicotine as a psychostimulant on ambulatory activity in mice. 2012 ISRN Pharmacol pmid:22530136
Pertusa M et al. N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons. 2012 J. Biol. Chem. pmid:22493431
Hardaker L et al. The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases. 2012 Respir. Res. pmid:22475739
Nagamatsu R et al. Cleavage of α-dicarbonyl compounds by terpene hydroperoxide. 2012 Biosci. Biotechnol. Biochem. pmid:23047102
Taher YA Antinociceptive activity of Mentha piperita leaf aqueous extract in mice. 2012 Libyan J Med pmid:22468149
Voets T et al. Transient receptor potential channel promiscuity frustrates constellation pharmacology. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:23093678
Hoy NY et al. New concepts in median nail dystrophy, onychomycosis, and hand, foot, and mouth disease nail pathology. 2012 ISRN Dermatol pmid:22462009
Wang S et al. Warmth suppresses and desensitizes damage-sensing ion channel TRPA1. 2012 Mol Pain pmid:22458587
Muscat JE Menthol cigarettes and lung cancer mortality. 2012 Nicotine Tob. Res. pmid:23012334
Avrahami D et al. A randomized, placebo-controlled double-blinded comparative clinical study of five over-the-counter non-pharmacological topical analgesics for myofascial pain: single session findings. 2012 Chiropr Man Therap pmid:22436614
Rostron B Response to "menthol cigarettes and lung cancer mortality". 2012 Nicotine Tob. Res. pmid:23012335
Sanders E et al. Does the use of ingredients added to tobacco increase cigarette addictiveness?: a detailed analysis. 2012 Inhal Toxicol pmid:22429143
Marsh L et al. A refreshing poison: one-quarter of young New Zealand smokers choose menthol. 2012 Aust N Z J Public Health pmid:23025381
Yoshihara M and Ito K Acute genetic manipulation of neuronal activity for the functional dissection of neural circuits-a dream come true for the pioneers of behavioral genetics. 2012 J. Neurogenet. pmid:22420407
Spanopoulos D et al. Retail price and point of sale display of tobacco in the UK: a descriptive study of small retailers. 2012 PLoS ONE pmid:22242183
Brunzell DH and McIntosh JM Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia. 2012 Neuropsychopharmacology pmid:22169946
Hirata H and Oshinsky ML Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels. 2012 J. Neurophysiol. pmid:22114162
Ford AP In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. 2012 Purinergic Signal. pmid:22095157
Ciuman RR Phytotherapeutic and naturopathic adjuvant therapies in otorhinolaryngology. 2012 Eur Arch Otorhinolaryngol pmid:21922427
Carvalho CO et al. The anthelmintic effect of plant extracts on Haemonchus contortus and Strongyloides venezuelensis. 2012 Vet. Parasitol. pmid:21872995
Zhang Y et al. Chinese herbal formula xiao yao san for treatment of depression: a systematic review of randomized controlled trials. 2012 Evid Based Complement Alternat Med pmid:21869903
Böhm M et al. Liposomes: a new non-pharmacological therapy concept for seasonal-allergic-rhinoconjunctivitis. 2012 Eur Arch Otorhinolaryngol pmid:21761190
Shiba T et al. Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model. 2012 Toxicol. Appl. Pharmacol. pmid:22935519
Gonseth S et al. The tobacco industry's past role in weight control related to smoking. 2012 Eur J Public Health pmid:21474548
Qin F et al. Quality control of modified xiaoyao san through the determination of 22 active components by ultra-performance liquid chromatography. 2011 Nov-Dec J AOAC Int pmid:22320084
Jiang MH et al. Comparative GC/MS analysis of essential oils extracted by 3 methods from the bud of Citrus aurantium L. var. amara Engl. 2011 Nov-Dec J. Food Sci. pmid:22416680
Kozyreva TV et al. [Relationship of single-nucleotide polymorphism rs11562975 in thermo-sensitive ion channel TRPM8 gene with human sensitivity to cold and menthol]. 2011 Mar-Apr Fiziol Cheloveka pmid:21542321
Hooper MW et al. Menthol cigarette smoking and health, Florida 2007 BRFSS. 2011 Jan-Feb Am J Health Behav pmid:20950154
Derby R et al. Novel treatment of onychomycosis using over-the-counter mentholated ointment: a clinical case series. 2011 Jan-Feb J Am Board Fam Med pmid:21209346
Pinault LL and Hunter FF Malaria Knowledge, Concern, Land Management, and Protection Practices among Land Owners and/or Managers in Lowland versus Highland Ecuador. 2011 Malar Res Treat pmid:22363897
Samad A et al. The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1. 2011 Biochem. J. pmid:20946100
Barbalho SM et al. Metabolic Profile of Offspring from Diabetic Wistar Rats Treated with Mentha piperita (Peppermint). 2011 Evid Based Complement Alternat Med pmid:21647314
Myrer JW et al. Topical analgesic added to paraffin enhances paraffin bath treatment of individuals with hand osteoarthritis. 2011 Disabil Rehabil pmid:20617919
Hu K et al. Two-dimensional concurrent HMQC-COSY as an approach for small molecule chemical shift assignment and compound identification. 2011 J. Biomol. NMR pmid:21373839
Nagle A et al. Efficacy study of vesicular gel containing methotrexate and menthol combination on parakeratotic rat skin model. 2011 J Liposome Res pmid:20557280
Arora R et al. Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud. 2011 Evid Based Complement Alternat Med pmid:20976081
Hiki N et al. Antiperistaltic effect and safety of L-menthol sprayed on the gastric mucosa for upper GI endoscopy: a phase III, multicenter, randomized, double-blind, placebo-controlled study. 2011 Gastrointest. Endosc. pmid:21353674
Dyer C Tobacco firms move to stop FDA banning menthol cigarettes. 2011 BMJ pmid:21363858
Ebihara S et al. Stimulating oral and nasal chemoreceptors for preventing aspiration pneumonia in the elderly. 2011 Yakugaku Zasshi pmid:22129860
Boyle S and Walters MR Clinically significant interaction between warfarin and popular cough lozenges 'Fisherman's Friend'. 2011 BMJ Case Rep pmid:22675107
Siegel M A lost opportunity for public health--the FDA advisory committee report on menthol. 2011 N. Engl. J. Med. pmid:21542736
Benowitz NL and Samet JM The threat of menthol cigarettes to U.S. public health. 2011 N. Engl. J. Med. pmid:21542737
Hiki N et al. A phase I study evaluating tolerability, pharmacokinetics, and preliminary efficacy of L-menthol in upper gastrointestinal endoscopy. 2011 Clin. Pharmacol. Ther. pmid:21544078
Lee YO and Glantz SA Menthol: putting the pieces together. 2011 Tob Control pmid:21504926
Klausner K Menthol cigarettes and smoking initiation: a tobacco industry perspective. 2011 Tob Control pmid:21504927
Fortes AM et al. Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening. 2011 BMC Plant Biol. pmid:22047180
Konidala U et al. Efficacy of various disinfectants on microbially contaminated toothbrushes due to brushing. 2011 Contemp Clin Dent pmid:22346157
Malhotra S and Yeltiwar RK Evaluation of two mouth rinses in reduction of oral malodor using a spectrophotometric technique. 2011 J Indian Soc Periodontol pmid:22028512
Zhao K et al. Perceiving nasal patency through mucosal cooling rather than air temperature or nasal resistance. 2011 PLoS ONE pmid:22022361
Annan K et al. Acaricidal effect of an isolate from Hoslundia opposita vahl against Amblyomma variegatum (Acari: Ixodidae). 2011 Pharmacognosy Res pmid:22022167
Thompson N et al. Unannounced telephone pill counts for assessing varenicline adherence in a pilot clinical trial. 2011 Patient Prefer Adherence pmid:22003285
Fard BK et al. Effectiveness of Mouth Washes on Streptococci in Plaque around Orthodontic Appliances. 2011 ISRN Dent pmid:21991490
Topp R et al. Effect of topical menthol on ipsilateral and contralateral superficial blood flow following a bout of maximum voluntary muscle contraction. 2011 Int J Sports Phys Ther pmid:21713232
Olszowy P et al. Poly(3-alkylthiophenes): new sorption materials for solid phase microextraction of drugs isolated from human plasma. 2011 Anal Bioanal Chem pmid:21710286
Lacouture ME et al. Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. 2011 Support Care Cancer pmid:21630130
Medbø A et al. "I did not intend to stop. I just could not stand cigarettes any more." A qualitative interview study of smoking cessation among the elderly. 2011 BMC Fam Pract pmid:21627833
Hoffman AC The health effects of menthol cigarettes as compared to non-menthol cigarettes. 2011 Tob Induc Dis pmid:21624153
Schleheck D et al. Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-1(T)). 2011 Stand Genomic Sci pmid:22675581
Holzer P Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system. 2011 Pharmacol. Ther. pmid:21420431
Tajino K et al. Cooling-sensitive TRPM8 is thermostat of skin temperature against cooling. 2011 PLoS ONE pmid:21407809
Raja AF et al. Antistaphylococcal and biofilm inhibitory activities of acetyl-11-keto-β-boswellic acid from Boswellia serrata. 2011 BMC Microbiol. pmid:21406118
Nilius B and Owsianik G The transient receptor potential family of ion channels. 2011 Genome Biol. pmid:21401968
Gasperini RJ et al. TRPM8 and Nav1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons. 2011 Mol Neurodegener pmid:21375738