(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Uveitis, Posterior D015866 5 associated lipids
Endophthalmitis D009877 12 associated lipids
Pain D010146 64 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Tsuzuki K et al. Menthol-induced Ca2+ release from presynaptic Ca2+ stores potentiates sensory synaptic transmission. 2004 J. Neurosci. pmid:14736862
Anagnostopoulos GK et al. Liver cirrhosis observed in a patient with chronic excessive menthol intake. 2004 J. Gastroenterol. Hepatol. pmid:14731143
Gandolfi M et al. Preimaginal learning determines adult response to chemical stimuli in a parasitic wasp. 2003 Proc. Biol. Sci. pmid:14728786
Narishetty ST and Panchagnula R Transdermal delivery system for zidovudine: in vitro, ex vivo and in vivo evaluation. 2004 Biopharm Drug Dispos pmid:14716748
Thomas NS and Panchagnula R Combination strategies to enhance transdermal permeation of zidovudine (AZT). 2003 Pharmazie pmid:14703969
Yong CS et al. Enhanced rectal bioavailability of ibuprofen in rats by poloxamer 188 and menthol. 2004 Int J Pharm pmid:14698588
Spichiger M et al. Determination of menthol in plasma and urine of rats and humans by headspace solid phase microextraction and gas chromatography--mass spectrometry. 2004 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:14659442
Hendradi E et al. Effect of mixed micelle formulations including terpenes on the transdermal delivery of diclofenac. 2003 Biol. Pharm. Bull. pmid:14646182
pmid:14619217
Nuessli J et al. Crystal structure of amylose complexes with small ligands. 2003 Int. J. Biol. Macromol. pmid:14607368
Shahverdi AR et al. Inhibition of nitrofurantoin reduction by menthol leads to enhanced antimicrobial activity. 2003 J Chemother pmid:14598936
Lin JP et al. Effects of (-)-menthol on the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats. 2003 Sep-Oct In Vivo pmid:14598608
Moleyar V and Narasimham P Antibacterial activity of essential oil components. 1992 Int. J. Food Microbiol. pmid:1457292
Turina AV et al. Monoterpenes affect chlorodiazepoxide-micelle interaction through micellar dipole potential modifications. 2003 Biochim. Biophys. Acta pmid:14561468
Cabanes C et al. Differential thermosensitivity of sensory neurons in the guinea pig trigeminal ganglion. 2003 J. Neurophysiol. pmid:14534264
Chang CE and Gilson MK Tork: Conformational analysis method for molecules and complexes. 2003 J Comput Chem pmid:14531053
Miyazawa M et al. Biopreparation of (-)-(1S,3R,4S,6S)-6-hydroxymenthol and (-)-(1S,3R,4S)-1-hydroxymenthol from 1-menthol by Rhizoctonia solani AG-1-IA and IB. 2003 Nat. Prod. Res. pmid:14526907
Okuyemi KS et al. Does menthol attenuate the effect of bupropion among African American smokers? 2003 Addiction pmid:14519175
Brooks DR et al. Menthol cigarettes and risk of lung cancer. 2003 Am. J. Epidemiol. pmid:14507595
Garten S and Falkner RV Continual smoking of mentholated cigarettes may mask the early warning symptoms of respiratory disease. 2003 Prev Med pmid:14507484
Frasnelli J and Hummel T Age-related decline of intranasal trigeminal sensitivity: is it a peripheral event? 2003 Brain Res. pmid:14499964
NEUDERT W and HUBER J [Double freezing point and a gas chromatographic method for the qualitative investigation of DL-menthols]. 1962 Arch Pharm pmid:14479160
MAKHKAMOV SM [On the problem of the preparation and research on validol tablets]. 1962 Jan-Feb Aptechn Delo pmid:14468699
Nelson SD et al. Investigations of mechanisms of reactive metabolite formation from (R)-(+)-pulegone. 1992 Sep-Oct Xenobiotica pmid:1441606
[Not Available]. 1954 Ann Pharm Fr pmid:14362140
MAMMANA A and BASSI A [Treatment of cholecystitis]. 1954 Rass Int Clin Ter pmid:14357640
LASHCHENKO DV [TERMONEPHELOMETRIC METHOD FOR THE QUANTITATIVE DETERMINATION OF VALIDOL AND MENTHOL IN TABLETS]. 1965 Farm Zh pmid:14348012
STOREY ID SOME DIFFERENCES IN THE CONJUGATION OF O-AMINOPHENOL AND P-NITROPHENOL BY THE URIDINE DIPHOSPHATE TRANSGLUCURONYLASE OF MOUSE-LIVER HOMOGENATES. 1965 Biochem. J. pmid:14333559
MAMEESH MS et al. STUDIES ON GLUCURONIDE DETOXICATION MECHANISMS IN VITAMIN A DEFICIENT RATS. 1965 Acta Pharmacol Toxicol (Copenh) pmid:14328197
Soen G et al. Corneal erosions and encephalopathy following exposure to "Rhino-Caps". 1992 May-Jun J Pediatr Ophthalmol Strabismus pmid:1432508
ZILSTORFF K SENSE OF SMELL ALTERATIONS BY COCAINE AND TETRACAINE. 1965 Arch Otolaryngol pmid:14310180
HUTTUNEN JK and MIETTINEN TA GLUCURONIDATION IN RATS OF DIFFERENT AGES AND STRAINS. 1965 Jan-Feb Acta Physiol. Scand. pmid:14286761
BETTECKEN F [NIL NOCERE'. TOXIC SYMPTOMS IN INFANTS AFTER USE OF METHOL-CONTAINING OINTMENTS]. 1964 Munch Med Wochenschr pmid:14255788
DRUCKER WD et al. ON THE RATE OF FORMATION OF STERIDAL GLUCURONOSIDES IN PATIENTS WITH FAMILIAL AND ACQUIRED JAUNDICE. 1964 J. Clin. Invest. pmid:14236219
FRIDERICH H [ON THE CONSERVATIVE TREATMENT OF THE ANORECTAL VARICOSE SYMPTOM COMPLEX IN MEDICAL PRACTICE]. 1964 Wien Med Wochenschr pmid:14219996
DATE T [EXPERIMENTAL AND CLINICAL STUDIES ON THE INFLUENCE OF BETA-GLUCURONIDASE INHIBITOR ON THE LIVING BODY]. 1964 Nippon Naika Gakkai Zasshi pmid:14219696
REGDON-KISS E [STUDIES ON THE SOLUBILITY OF SOME DRUGS]. 1963 Pharmazie pmid:14206114
SZABO L and EBREY PB [HEREDITY TESTS WITH MENTHOL IN CRIGLER-NAJJAR DISEASE]. 1964 Orv Hetil pmid:14205783
WU MC et al. [EFFECT OF GIBBERELLIN ON THE GROWTH AND OIL CONTENT OF MENTHA ARVENSIS L]. 1964 Yao Xue Xue Bao pmid:14201075
Awan KJ Microhyphema. 1977 Can. J. Ophthalmol. pmid:141972
PAPA CM and SHELLEY WB MENTHOL HYPERSENSITIVITY; DIAGNOSTIC BASOPHIL RESPONSE IN A PATIENT WITH CHRONIC URTICARIA, FLUSHING, AND HEADACHES. 1964 JAMA pmid:14162561
LIUBOVICH VI [TREATMENT OF ANGINA PECTORIS AND PREVENTION OF CORONARY THROMBOSIS WITH VALOHEPAR]. 1964 Jan-Feb Kardiologiia pmid:14152592
VILENSKII DN [CLINICAL VARIATIONS OF THE ACTION OF NARCOTICS IN A PROTRACTED ATTACK OF ANGINA PECTORIS]. 1963 Sov Med pmid:14150364
Green BG The sensory effects of l-menthol on human skin. 1992 Somatosens Mot Res pmid:1414120
DOEVING KB STUDIES OF THE RELATION BETWEEN THE FROG'S ELECTRO-OLFACTOGRAM (EOG) AND SINGLE UNIT ACTIVITY IN THE OLFACTORY BULB. 1964 Jan-Feb Acta Physiol. Scand. pmid:14133569
Sant'Ambrogio FB et al. Menthol in the upper airway depresses ventilation in newborn dogs. 1992 Respir Physiol pmid:1410843
PICCOLI A [THE L-MENTHYL ESTER OF D-PANTOTHENIC ACID IN THE TREATMENT OF SOME RHINOPATHIES]. 1963 Sep-Oct Ann Laringol Otol Rinol Faringol pmid:14091285
TAYLOR R CHEMICAL STIMULANTS TO RESPIRATION. 1963 Appl Ther pmid:14084568
CIAULA V [ON THE REPARATIVE ACTIVITY OF AN OINTMENT CONTAINING MENTHYL PANTOTHENATE IN HUMAN SKIN ULCERATIONS]. 1963 Minerva Dermatol pmid:14083381
BAHJAT KS DETERMINATION OF CAMPHOR AND MENTHOL IN PHARMACEUTICAL PRODUCTS BY GAS CHROMATOGRAPHY. 1963 J Pharm Sci pmid:14076493
pmid:14066746
PASCHOUD JM [SOME CASES OF CONTACT ECZEMA WITH GROUP SENSITIZATION]. 1963 Dermatologica pmid:14055606
SZABO L and EBREY P STUDIES ON THE INHERITANCE OF CRIGLER--NAJJAR'S SYNDROME BY THE MENTHOL TEST. 1963 Acta Paediatr Acad Sci Hung pmid:14051149
COHEN SL and SCHOENE FC Lipoid pneumonia. A case report. 1963 Ariz Med pmid:14022102
KAGANOVSKAIA MI et al. [Conversion of methone into menthol in menthol industry wastes]. 1962 Med Prom SSSR pmid:13958256
PERKINS ME The New York City Community Mental Health Board: a progress report. 1962 Am J Public Health Nations Health pmid:13942452
MESSEK H [The effect of different vasoconstrictors on various qualities of the nasal mucosa]. 1962 Monatsschr Ohrenheilkd Laryngorhinol pmid:13935128
MATZKE H [Interval treatment of angina pectoris with Nitrodurat]. 1962 Munch Med Wochenschr pmid:13933949
DMITRIEVA NM et al. [Comparative effects of synthetic and natural menthol]. 1962 Farm Zh pmid:13886714
BECK K and RICHTER E [On glucuronic acid excretion in the urine after menthol loading in hepatitis and obstructive jaundice]. 1962 Med Klin pmid:13866288
BLAKE MI The quantitative determination of free menthol in peppermint oil. 1960 J Am Pharm Assoc Am Pharm Assoc pmid:13849072
ELDER TD et al. Some steroid hormone-like effects of menthol. 1960 Science pmid:13819868
CAUJOLLE F and MEYNIER D [Pharmacodynamic effects of carquejol]. 1959 C. R. Hebd. Seances Acad. Sci. pmid:13808521
BOURNOT K [Proposals for the DAB 7. Part 2. Menthol and vanillin]. 1960 Pharmazie pmid:13803358
VON BOHME H and VAN EMSTER K [On the assay of DL-menthol for contamination by DL-neomenthol. 2. Report on the menthol monography in a new German pharmacopoeia]. 1960 Arch Pharm pmid:13801997
BOEHME H et al. [On the menthol monography in a new German pharmocopoeia. Part I]. 1960 Arch Pharm pmid:13801996
HUECKEL W and JORDAN E [The isomerization of menthol and the 3 enol acetats of 3-menthanone]. 1961 Arch Pharm pmid:13716537
Trudgill PW Microbial metabolism of monoterpenes--recent developments. 1990 Biodegradation pmid:1368150
Ringer KL et al. Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint. 2003 Arch. Biochem. Biophys. pmid:13679086
Orihara Y et al. Triglucosylation on the biotransformation of (+)-menthol by cultured cells of Eucalyptus perriniana. 1991 Phytochemistry pmid:1367340
Gray CJ et al. Immobilization of lipase from Candida cylindraceae and its use in the synthesis of menthol esters by transesterification. 1990 Enzyme Microb. Technol. pmid:1366804
HOPKINS LV and BLAKE MI Paper chromatographic evaluation of menthol. 1959 J Am Pharm Assoc Am Pharm Assoc (Baltim) pmid:13641059
VAN OS FH [Determination of the menthol content in peppermint oil in volume VI of the Pharmacopeia]. 1959 Pharm Weekbl pmid:13633433
BOGNER RL and GRUBB TC Studies on the inhalation of vapors from radioactive menthol and camphor. 1959 J Am Pharm Assoc Am Pharm Assoc (Baltim) pmid:13610734
BOURNOT K [Proposals for German Pharmacopeia. 7th edition]. 1958 Pharmazie pmid:13578642
BOURNOT K [Proposals for the German Pharmacopeia, 7th edition]. 1958 Pharm Zentralhalle Dtschl pmid:13566967
ZBASOV IT and BEIBUTOV ShM [Application of validol in radiation sickness caused by roentgeno-radiotherapy]. 1957 Jul-Aug Vestn Rentgenol Radiol pmid:13530586
Greco PJ and Ende J Pruritus: a practical approach. 1992 May-Jun J Gen Intern Med pmid:1351941
pmid:13438720
DASSLER HG [Physiological effect of menthofuran]. 1957 Pharmazie pmid:13419506
BLAKE MI et al. The determination of free menthol in peppermint oil by chromatographic analysis. 1956 J Am Pharm Assoc Am Pharm Assoc (Baltim) pmid:13376355
HEILGEMEIR G [Synergy of drug and vehicle in the treatment of itching dermatoses]. 1955 Medizinische pmid:13287620
pmid:13282732
pmid:13271208
pmid:13228114
pmid:13211401
LEMLI JA [Determination of menthone, menthol and menthofuran in essential oil of Mentha; localization of menthofuran in the plant]. 1954 Ann Pharm Fr pmid:13189199
RAKIETEN N et al. Effects of menthol vapor on the intact animal with special reference to the upper respiratory tract. 1954 J Am Pharm Assoc Am Pharm Assoc (Baltim) pmid:13183832
Kodash AG et al. [Harvesting times for "Kubanskaia-6" peppermint]. 1976 Farmatsiia pmid:131720
JEROME H and LECHAT P [Therapeutic study of mentholated preparations]. 1953 Therapie pmid:13169062
SURKIN DP and POPOVA TK [Effectiveness of therapy of chronic tonsillitis of oil menthol-penicillin inhalation]. 1953 Sep-Oct Pediatriia pmid:13133607
pmid:13123997
SWINTOSKY JV et al. The liquid-liquid counter current separation of a menthol-menthyl acetate mixture. 1953 J Am Pharm Assoc Am Pharm Assoc (Baltim) pmid:13108763
ELIEL EL The origin of steric hindrance in cyclohexane derivatives. 1953 Experientia pmid:13068384
MARCHE J [Recent data on the therapeutic properties of hydrosoluble terpene oxides]. 1953 Gaz Med Fr pmid:13052196
Kin M [Pitfalls of thinking that "I am familiar with this condition". Why the menthol compress]. 1992 Kango pmid:1305207
CAUJOLLE F et al. [Toxicity of cyclohexanone and some homologous ketones]. 1953 C. R. Hebd. Seances Acad. Sci. pmid:13051876
FISCHER L et al. A study of the relationship of viscosity to free menthol content of Oregon and Washington peppermint oils. 1953 J Am Pharm Assoc Am Pharm Assoc (Baltim) pmid:13034622
Fujisawa S and Kadoma Y Effect of phenolic compounds on the polymerization of methyl methacrylate. 1992 Dent Mater pmid:1303375
MILLER CE A note on the preparation of 1-menthyl acetate. 1952 J Am Pharm Assoc Am Pharm Assoc (Baltim) pmid:13022430