| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uveitis, Posterior | D015866 | 5 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Pain | D010146 | 64 associated lipids |
Total
3
(-)-Menthol
(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.
Cross Reference
Introduction
To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Menthol?
(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Menthol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Menthol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Menthol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (-)-Menthol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Menthol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (-)-Menthol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Menthol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Menthol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Patel T and Yosipovitch G | The management of chronic pruritus in the elderly. | 2010 | Skin Therapy Lett. | pmid:20844849 |
| Green BG | The sensory effects of l-menthol on human skin. | 1992 | Somatosens Mot Res | pmid:1414120 |
| Trongtokit Y et al. | Efficacy of repellent products against caged and free flying Anopheles stephensi mosquitoes. | 2005 | Southeast Asian J. Trop. Med. Public Health | pmid:16610644 |
| VILENSKII DN | [CLINICAL VARIATIONS OF THE ACTION OF NARCOTICS IN A PROTRACTED ATTACK OF ANGINA PECTORIS]. | 1963 | Sov Med | pmid:14150364 |
| Zhmurkin VP et al. | [Non-coronary effects of coronary agents]. | 1977 | Sov Med | pmid:403615 |
| Rajput SB and Karuppayil SM | Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans. | 2013 | Springerplus | pmid:23449869 |
| Schleheck D et al. | Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-1(T)). | 2011 | Stand Genomic Sci | pmid:22675581 |
| Sziegoleit W et al. | [The prevention of pain after tooth extraction using topically applied acetyl-salicylic acid (Grisaldon)]. | 1982 | Stomatol DDR | pmid:6956029 |
| Smith AP and Boden C | Effects of chewing menthol gum on the alertness of healthy volunteers and those with an upper respiratory tract illness. | 2013 | Stress Health | pmid:22674677 |
| Lacouture ME et al. | Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. | 2011 | Support Care Cancer | pmid:21630130 |
| Fallon MT et al. | Cancer treatment-related neuropathic pain: proof of concept study with menthol--a TRPM8 agonist. | 2015 | Support Care Cancer | pmid:25680765 |
| Dunér-Engström M et al. | Effect of nicotine chewing gum on salivary secretion. | 1986 | Swed Dent J | pmid:3460195 |
| Foss S and Harder J | Thauera linaloolentis sp. nov. and Thauera terpenica sp. nov., isolated on oxygen-containing monoterpenes (linalool, menthol, and eucalyptol) nitrate. | 1998 | Syst. Appl. Microbiol. | pmid:9841126 |
| Zougagh M et al. | Supercritical fluid extraction--achiral liquid chromatography with circular dichroism detection for the determination of menthone enantiomers in natural peppermint oil samples. | 2009 | Talanta | pmid:19559879 |
| Mose VT | [Allergic reactions to toothpaste]. | 1974 | Tandlaegebladet | pmid:4536313 |
| JEROME H and LECHAT P | [Therapeutic study of mentholated preparations]. | 1953 | Therapie | pmid:13169062 |
| DASTUGUE G and BRUN G | [Pharmacodynamic actions of some aqueous solutions of plant oils]. | 1952 | Therapie | pmid:14950807 |
| Morice AH et al. | Effect of inhaled menthol on citric acid induced cough in normal subjects. | 1994 | Thorax | pmid:7974298 |
| Murayama M and Kumaroo KK | Inhibitors of ex vivo aggregation of human platelets induced by decompression, during reduced barometric pressure. | 1986 | Thromb. Res. | pmid:3715814 |
| Bolcic-Jankovic D and Biener L | Public opinion about FDA regulation of menthol and nicotine. | 2015 | Tob Control | pmid:24638964 |
| Assunta M | Indonesia: World Cup déjà vu. | 2010 | Tob Control | pmid:20671090 |
| McDaniel PA and Malone RE | "I always thought they were all pure tobacco": American smokers' perceptions of "natural" cigarettes and tobacco industry advertising strategies. | 2007 | Tob Control | pmid:18048597 |
| Lee YO and Glantz SA | Menthol: putting the pieces together. | 2011 | Tob Control | pmid:21504926 |
| Klausner K | Menthol cigarettes and smoking initiation: a tobacco industry perspective. | 2011 | Tob Control | pmid:21504927 |
| Anderson SJ | Marketing of menthol cigarettes and consumer perceptions: a review of tobacco industry documents. | 2011 | Tob Control | pmid:21504928 |
| Yerger VB | Menthol's potential effects on nicotine dependence: a tobacco industry perspective. | 2011 | Tob Control | pmid:21504929 |
| Yerger VB and McCandless PM | Menthol sensory qualities and smoking topography: a review of tobacco industry documents. | 2011 | Tob Control | pmid:21504930 |
| Salgado MV and Glantz SA | Direct disease-inducing effects of menthol through the eyes of tobacco companies. | 2011 | Tob Control | pmid:21504931 |
| Osaki Y et al. | Adolescent smoking behaviour and cigarette brand preference in Japan. | 2006 | Tob Control | pmid:16728747 |
| Anderson SJ | Menthol cigarettes and smoking cessation behaviour: a review of tobacco industry documents. | 2011 | Tob Control | pmid:21504932 |
| Hickman NJ et al. | Menthol use among smokers with psychological distress: findings from the 2008 and 2009 National Survey on Drug Use and Health. | 2014 | Tob Control | pmid:22821797 |
| Hyland A et al. | Mentholated cigarettes and smoking cessation: findings from COMMIT. Community Intervention Trial for Smoking Cessation. | 2002 | Tob Control | pmid:12035007 |
| Muscat JE et al. | Mentholated cigarettes and smoking habits in whites and blacks. | 2002 | Tob Control | pmid:12432163 |
| Assunta M and Chapman S | A "clean cigarette" for a clean nation: a case study of Salem Pianissimo in Japan. | 2004 | Tob Control | pmid:15564222 |
| King B et al. | Malaysian and Thai smokers' beliefs about the harmfulness of 'light' and menthol cigarettes. | 2010 | Tob Control | pmid:20852322 |
| Pollay RW and Dewhirst T | The dark side of marketing seemingly "Light" cigarettes: successful images and failed fact. | 2002 | Tob Control | pmid:11893811 |
| Slaughter E et al. | Toxicity of cigarette butts, and their chemical components, to marine and freshwater fish. | 2011 | Tob Control | pmid:21504921 |
| Stevens D and Glantz S | Tobacco documents reveal questionable professional recertification by industry menthol expert. | 2016 | Tob Control | pmid:25967941 |
| Kostygina G et al. | Tobacco industry use of flavours to recruit new users of little cigars and cigarillos. | 2016 | Tob Control | pmid:25354674 |
| Anderson SJ et al. | Tobacco documents research methodology. | 2011 | Tob Control | pmid:21504933 |
| Lawrence D et al. | Sensory properties of menthol and smoking topography. | 2011 | Tob Induc Dis | pmid:21624149 |
| Johnson DM et al. | Designing a tobacco counter-marketing campaign for African American youth. | 2008 | Tob Induc Dis | pmid:18822164 |
| Nsimba SE and Sussman S | Tobacco advertisements and promotion industry on smoking in Tanzania: a review of negative public health implications for current and future generations. | 2006 | Tob Induc Dis | pmid:19570296 |
| Difranza JR et al. | Cigarette package design: opportunities for disease prevention. | 2002 | Tob Induc Dis | pmid:19570250 |
| Hoffman AC | The health effects of menthol cigarettes as compared to non-menthol cigarettes. | 2011 | Tob Induc Dis | pmid:21624153 |
| Hoffman AC and Miceli D | Menthol cigarettes and smoking cessation behavior. | 2011 | Tob Induc Dis | pmid:21624152 |
| Hoffman AC and Simmons D | Menthol cigarette smoking and nicotine dependence. | 2011 | Tob Induc Dis | pmid:21624151 |
| Rising J and Wasson-Blader K | Menthol and initiation of cigarette smoking. | 2011 | Tob Induc Dis | pmid:21624150 |
| Rising J and Alexander L | Marketing of menthol cigarettes and consumer perceptions. | 2011 | Tob Induc Dis | pmid:21624148 |
| Caraballo RS and Asman K | Epidemiology of menthol cigarette use in the United States. | 2011 | Tob Induc Dis | pmid:21624147 |
| Hoffman AC | Introduction: Mentholated cigarettes and public health. | 2011 | Tob Induc Dis | pmid:21624146 |
| Shiba T et al. | Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22935519 |
| Mølck AM et al. | Lack of histological cerebellar changes in Wistar rats given pulegone for 28 days. Comparison of immersion and perfusion tissue fixation. | 1998 | Toxicol. Lett. | pmid:9635415 |
| Kurohane K et al. | Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice. | 2013 | Toxicol. Lett. | pmid:23296101 |
| Paschke M et al. | Activation of the cold-receptor TRPM8 by low levels of menthol in tobacco products. | 2017 | Toxicol. Lett. | pmid:28238800 |
| Madsen C et al. | Short-term toxicity study in rats dosed with menthone. | 1986 Jul-Aug | Toxicol. Lett. | pmid:3738926 |
| Kristiansen E and Madsen C | Induction of protein droplet (alpha 2 mu-globulin) nephropathy in male rats after short-term dosage with 1,8-cineole and l-limonene. | 1995 | Toxicol. Lett. | pmid:7482582 |
| Thorup I et al. | Short term toxicity study in rats dosed with pulegone and menthol. | 1983 | Toxicol. Lett. | pmid:6658833 |
| Hartmann A and Speit G | The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay). | 1997 | Toxicol. Lett. | pmid:9067486 |
| De-Oliveira AC et al. | In vitro inhibition of liver monooxygenases by beta-ionone, 1,8-cineole, (-)-menthol and terpineol. | 1999 | Toxicology | pmid:10454222 |
| Moorthy B et al. | Hepatotoxicity of pulegone in rats: its effects on microsomal enzymes, in vivo. | 1989 | Toxicology | pmid:2541521 |
| Dambolena JS et al. | Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. | 2008 | Toxicon | pmid:18037463 |
| Wildung MR and Croteau RB | Genetic engineering of peppermint for improved essential oil composition and yield. | 2005 | Transgenic Res. | pmid:16201403 |
| Cox LS et al. | Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data. | 2011 | Trials | pmid:21266057 |
| Romero MC et al. | Peppermint (Mentha piperita) and albendazole against anisakiasis in an animal model. | 2014 | Trop. Med. Int. Health | pmid:25330410 |
| Ciftçi O et al. | Mentholated cigarette smoking and brachial artery, carotid artery, and aortic vascular function. | 2009 | Turk Kardiyol Dern Ars | pmid:19717955 |
| Salisová M et al. | Comparison of conventional and ultrasonically assisted extractions of pharmaceutically active compounds from Salvia officinalis. | 1997 | Ultrason Sonochem | pmid:11237030 |
| Nomoto Y et al. | Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. | 2008 | Urology | pmid:18336880 |
| Tsukimi Y et al. | Cold response of the bladder in guinea pig: involvement of transient receptor potential channel, TRPM8. | 2005 | Urology | pmid:15708076 |
| van den Bossche W et al. | [Gas chromatographic determination of various phenols and related compounds in drugs]. | 1975 | Verh. K. Acad. Geneeskd. Belg. | pmid:1189599 |
| ZBASOV IT and BEIBUTOV ShM | [Application of validol in radiation sickness caused by roentgeno-radiotherapy]. | 1957 Jul-Aug | Vestn Rentgenol Radiol | pmid:13530586 |
| Dalefield RR and Oehme FW | Detection of metabolites of a veterinary counter-irritant in canine urine. | 1998 | Vet Hum Toxicol | pmid:9682412 |
| Katiki LM et al. | Anthelmintic activity of Cymbopogon martinii, Cymbopogon schoenanthus and Mentha piperita essential oils evaluated in four different in vitro tests. | 2011 | Vet. Parasitol. | pmid:21820807 |
| Carvalho CO et al. | The anthelmintic effect of plant extracts on Haemonchus contortus and Strongyloides venezuelensis. | 2012 | Vet. Parasitol. | pmid:21872995 |
| Ribeiro JC et al. | Efficacy of free and nanoencapsulated Eucalyptus citriodora essential oils on sheep gastrointestinal nematodes and toxicity for mice. | 2014 | Vet. Parasitol. | pmid:24929446 |
| Gorelik MM et al. | [Clinical trial of synthetic menthol in angina pectoris]. | 1965 | Vrach Delo | pmid:5870960 |
| Richardson TL | African-American smokers and cancers of the lung and of the upper respiratory and digestive tracts. Is menthol part of the puzzle? | 1997 | West. J. Med. | pmid:9143194 |
| FRIDERICH H | [ON THE CONSERVATIVE TREATMENT OF THE ANORECTAL VARICOSE SYMPTOM COMPLEX IN MEDICAL PRACTICE]. | 1964 | Wien Med Wochenschr | pmid:14219996 |
| Sabzghabaee AM et al. | Role of menthol in treatment of candidial napkin dermatitis. | 2011 | World J Pediatr | pmid:21210268 |
| Sharara AI et al. | Split-dose menthol-enhanced PEG vs PEG-ascorbic acid for colonoscopy preparation. | 2015 | World J. Gastroenterol. | pmid:25684963 |
| Maji D et al. | A natural plant growth promoter calliterpenone from a plant Callicarpa macrophylla Vahl improves the plant growth promoting effects of plant growth promoting rhizobacteria (PGPRs). | 2013 | World J. Microbiol. Biotechnol. | pmid:23271460 |
| Nelson SD et al. | Investigations of mechanisms of reactive metabolite formation from (R)-(+)-pulegone. | 1992 Sep-Oct | Xenobiotica | pmid:1441606 |
| Madyastha KM and Gaikwad NW | Metabolic fate of S-(-)-pulegone in rat. | 1998 | Xenobiotica | pmid:9741951 |
| Madyastha KM and Raj CP | Studies on the metabolism of a monoterpene ketone, R-(+)-pulegone--a hepatotoxin in rat: isolation and characterization of new metabolites. | 1993 | Xenobiotica | pmid:8342298 |
| Moorthy B et al. | Metabolism of a monoterpene ketone, R-(+)-pulegone--a hepatotoxin in rat. | 1989 | Xenobiotica | pmid:2728495 |
| Southwell IA et al. | Metabolism of alpha- and beta-pinene, p-cymene and 1,8-cineole in the brushtail possum, Trichosurus vulpecula. | 1980 | Xenobiotica | pmid:7385912 |
| Boyle R et al. | Biotransformation of 1,8-cineole in the brushtail possum (Trichosurus vulpecula). | 2000 | Xenobiotica | pmid:11055269 |
| Ebihara S et al. | Stimulating oral and nasal chemoreceptors for preventing aspiration pneumonia in the elderly. | 2011 | Yakugaku Zasshi | pmid:22129860 |
| Oshiro S and Doi K | [Synthesis of DL-menthol]. | 1968 | Yakugaku Zasshi | pmid:5748842 |
| Shibata Y et al. | Comparison of pharmaceutical properties of topical non-steroidal anti-inflammatory drug preparations on quality of life. | 2005 | Yakugaku Zasshi | pmid:15863971 |
| Sekiguchi K et al. | [Wet grinding (pulverization by intervention) of solid drugs during compounding]. | 1983 | Yakugaku Zasshi | pmid:6864459 |
| Wickham RJ | How Menthol Alters Tobacco-Smoking Behavior: A Biological Perspective. | 2015 | Yale J Biol Med | pmid:26339211 |
| Ping QN et al. | [Role of stratum corneum and its lipids in permeability of 5-fluorouracil through human skin]. | 1993 | Yao Xue Xue Bao | pmid:8030417 |
| WU MC et al. | [EFFECT OF GIBBERELLIN ON THE GROWTH AND OIL CONTENT OF MENTHA ARVENSIS L]. | 1964 | Yao Xue Xue Bao | pmid:14201075 |
| Lou HX et al. | [New monoterpenoids from Cynanchum hancockianum]. | 1992 | Yao Xue Xue Bao | pmid:1293922 |
| Weitgasser H | [Experience with Phlebex]. | 1972 | Z Allgemeinmed | pmid:5034163 |
| Mahr H | [Percutaneous treatment of the so-called anginal disorders]. | 1974 | Z Allgemeinmed | pmid:4814872 |
| Aldinger-Mosseanu G | [Report on the use of pinimenthol bath]. | 1969 | Z Allgemeinmed | pmid:5772371 |
| Lotz H | [Therapeutic experiences with Dolo-Menthoneuringel]. | 1973 | Z Allgemeinmed | pmid:4269507 |
| Grisk A and Fischer W | [On the pulmonar excretion of cineole, menthol and thymol in rats following rectal application]. | 1969 | Z Arztl Fortbild (Jena) | pmid:5785479 |