| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uveitis, Posterior | D015866 | 5 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Pain | D010146 | 64 associated lipids |
Total
3
(-)-Menthol
(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.
Cross Reference
Introduction
To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Menthol?
(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Menthol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Menthol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Menthol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (-)-Menthol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Menthol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (-)-Menthol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Menthol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Menthol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:17499848 | ||||
| Bödding M et al. | Characterisation of TRPM8 as a pharmacophore receptor. | 2007 | Cell Calcium | pmid:17517434 |
| Facer P et al. | Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. | 2007 | BMC Neurol | pmid:17521436 |
| Jantharaprapap R and Stagni G | Effects of penetration enhancers on in vitro permeability of meloxicam gels. | 2007 | Int J Pharm | pmid:17531412 |
| Bautista DM et al. | The menthol receptor TRPM8 is the principal detector of environmental cold. | 2007 | Nature | pmid:17538622 |
| pmid:17566129 | ||||
| Chen H et al. | Hydrogel-thickened microemulsion for topical administration of drug molecule at an extremely low concentration. | 2007 | Int J Pharm | pmid:17570625 |
| pmid:17609957 | ||||
| Chen J | [Effect of quadruple fluid aerosol inhalation on oral mucositis induced by radiotherapy in nasopharyngeal carcinoma and its mechanism]. | 2007 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:17611340 |
| González N and Sumano H | Design of two liquid Ibuprofen-poloxamer-limonene or menthol preparations for dermal administration. | 2007 | Drug Deliv | pmid:17613016 |
| Wang CY et al. | Enhancing antioxidant, antiproliferation, and free radical scavenging activities in strawberries with essential oils. | 2007 | J. Agric. Food Chem. | pmid:17636936 |
| Williams JM et al. | Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia. | 2007 | Nicotine Tob. Res. | pmid:17654300 |
| Mint conditions. | 2007 | Harv Health Lett | pmid:17665507 | |
| Moore SJ et al. | A low-cost repellent for malaria vectors in the Americas: results of two field trials in Guatemala and Peru. | 2007 | Malar. J. | pmid:17678537 |
| pmid:17683869 | ||||
| Ferguson LJ et al. | 14C-labeled pulegone and metabolites binding to alpha2u-globulin in kidneys of male F-344 rats. | 2007 | J. Toxicol. Environ. Health Part A | pmid:17687727 |
| Wang NL et al. | Two new monoterpene glycosides and a new (+)-jasmololone glucoside from Bidens parviflora Willd. | 2007 Apr-Aug | J Asian Nat Prod Res | pmid:17701564 |
| Daniels RL and McKemy DD | Mice left out in the cold: commentary on the phenotype of TRPM8-nulls. | 2007 | Mol Pain | pmid:17705869 |
| pmid:17716715 | ||||
| Albin KC et al. | Modulation of oral heat and cold pain by irritant chemicals. | 2008 | Chem. Senses | pmid:17728277 |
| Tajino K et al. | Application of menthol to the skin of whole trunk in mice induces autonomic and behavioral heat-gain responses. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17761510 |
| Hunter KR et al. | Halothane and eucalyptol as alternatives to chloroform for softening gutta-percha. | 1991 | J Endod | pmid:1779214 |
| Penuelas A et al. | Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine. | 2007 | Eur. J. Pharmacol. | pmid:17825279 |
| pmid:17852768 | ||||
| Karashima Y et al. | Bimodal action of menthol on the transient receptor potential channel TRPA1. | 2007 | J. Neurosci. | pmid:17855602 |
| pmid:17873595 | ||||
| Millar ID et al. | Ion channel diversity, channel expression and function in the choroid plexuses. | 2007 | Cerebrospinal Fluid Res | pmid:17883837 |
| pmid:17888599 | ||||
| Chang JS et al. | The effect of mixed-solvent and terpenes on percutaneous absorption of meloxicam gel. | 2007 | Drug Dev Ind Pharm | pmid:17891585 |
| Phelps CB and Gaudet R | The role of the N terminus and transmembrane domain of TRPM8 in channel localization and tetramerization. | 2007 | J. Biol. Chem. | pmid:17908685 |
| Okuyemi KS et al. | Relationship between menthol cigarettes and smoking cessation among African American light smokers. | 2007 | Addiction | pmid:17916223 |
| Matta JA and Ahern GP | Voltage is a partial activator of rat thermosensitive TRP channels. | 2007 | J. Physiol. (Lond.) | pmid:17932142 |
| Hayashi S et al. | Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer. | 2007 | Inflammopharmacology | pmid:17943255 |
| Ulmer WT and Schött D | [Chronic obstructive bronchitis. Effect of Gelomyrtol forte in a placebo-controlled double-blind study]. | 1991 | Fortschr. Med. | pmid:1794831 |
| Shapira R and Mimran E | Isolation and characterization of Escherichia coli mutants exhibiting altered response to thymol. | 2007 | Microb. Drug Resist. | pmid:17949301 |
| Olivella MS et al. | Effects of dimethylformamide and L-menthol permeation enhancers on transdermal delivery of quercetin. | 2007 | Pharm Dev Technol | pmid:17963148 |
| Tiemann P et al. | Administration of Ratanhia-based herbal oral care products for the prophylaxis of oral mucositis in cancer chemotherapy patients: a clinical trial. | 2007 | Evid Based Complement Alternat Med | pmid:17965768 |
| Yamasaki M et al. | Cough reflex and oral chemesthesis induced by capsaicin and capsiate in healthy never-smokers. | 2007 | Cough | pmid:17971242 |
| Herkenne C et al. | In vivo methods for the assessment of topical drug bioavailability. | 2008 | Pharm. Res. | pmid:17985216 |
| Naito K et al. | The effect of L-menthol stimulation of the major palatine nerve on nasal patency. | 1991 | Auris Nasus Larynx | pmid:1799329 |
| pmid:17994363 | ||||
| Aulenta F et al. | Fragrance release from the surface of branched poly (amide)s. | 2005 | Molecules | pmid:18007278 |
| Carballeira JD et al. | High throughput screening and QSAR-3D/CoMFA: useful tools to design predictive models of substrate specificity for biocatalysts. | 2004 | Molecules | pmid:18007469 |
| pmid:18022442 | ||||
| Julius D | From peppers to peppermints: natural products as probes of the pain pathway. | 2005-2006 | Harvey Lect. | pmid:18030977 |
| Deluc LG et al. | Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development. | 2007 | BMC Genomics | pmid:18034876 |
| Dambolena JS et al. | Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. | 2008 | Toxicon | pmid:18037463 |
| McDaniel PA and Malone RE | "I always thought they were all pure tobacco": American smokers' perceptions of "natural" cigarettes and tobacco industry advertising strategies. | 2007 | Tob Control | pmid:18048597 |
| Zhao L et al. | Effect of O-acylmenthol on transdermal delivery of drugs with different lipophilicity. | 2008 | Int J Pharm | pmid:18053661 |
| Zanotto KL et al. | Cross-desensitization of responses of rat trigeminal subnucleus caudalis neurons to cinnamaldehyde and menthol. | 2008 | Neurosci. Lett. | pmid:18060696 |
| Zhao L et al. | Transdermal delivery of penetrants with differing lipophilicities using O-acylmenthol derivatives as penetration enhancers. | 2008 | Eur J Pharm Biopharm | pmid:18065216 |
| pmid:18065850 | ||||
| Xing H et al. | TRPM8 mechanism of cold allodynia after chronic nerve injury. | 2007 | J. Neurosci. | pmid:18077679 |
| Loi RX et al. | Solid-phase microextraction method for in vivo measurement of allelochemical uptake. | 2008 | J. Chem. Ecol. | pmid:18080164 |
| Ohshima T et al. | Highly Enantio- and s-trans C=C bond selective catalytic hydrogenation of cyclic enones: alternative synthesis of (-)-menthol. | 2008 | Chemistry | pmid:18080262 |
| Kondrats'kyÄ AP et al. | [Functional identification of the TRPM8 cold receptor in rat prostate epithelial cells]. | 2007 | Fiziol Zh | pmid:18080488 |
| Petrus M et al. | A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. | 2007 | Mol Pain | pmid:18086313 |
| Takashima Y et al. | Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons. | 2007 | J. Neurosci. | pmid:18094254 |
| Samarasekera R et al. | Insecticidal activity of menthol derivatives against mosquitoes. | 2008 | Pest Manag. Sci. | pmid:18095385 |
| ANDRADE MA | [Differential reactions of camphor, menthol and terpene hydrated]. | 1948 Sep-Dec | J Farm | pmid:18119741 |
| Yano T et al. | Effects of l-menthol and dl-camphor on the penetration and hydrolysis of methyl salicylate in hairless mouse skin. | 1991 | J. Pharmacobio-dyn. | pmid:1812275 |
| pmid:18142290 | ||||
| pmid:18177050 | ||||
| Macfarlane JT and Worboys M | The changing management of acute bronchitis in Britain, 1940-1970: the impact of antibiotics. | 2008 | Med Hist | pmid:18180811 |
| pmid:18197139 | ||||
| Dhaka A et al. | Visualizing cold spots: TRPM8-expressing sensory neurons and their projections. | 2008 | J. Neurosci. | pmid:18199758 |
| Meseguer V et al. | Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole. | 2008 | J. Neurosci. | pmid:18199759 |
| Haas AL et al. | Cigarette smoking in opioid-using patients presenting for hospital-based medical services. | 2008 Jan-Feb | Am J Addict | pmid:18214725 |
| pmid:18215479 | ||||
| Nassenstein C et al. | Expression and function of the ion channel TRPA1 in vagal afferent nerves innervating mouse lungs. | 2008 | J. Physiol. (Lond.) | pmid:18218683 |
| Dussor G et al. | Cutaneous sensory neurons expressing the Mrgprd receptor sense extracellular ATP and are putative nociceptors. | 2008 | J. Neurophysiol. | pmid:18234974 |
| Brady D et al. | Spherezymes: a novel structured self-immobilisation enzyme technology. | 2008 | BMC Biotechnol. | pmid:18237402 |
| pmid:18247142 | ||||
| pmid:18251800 | ||||
| Mu TW et al. | Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis. | 2008 | PLoS Biol. | pmid:18254660 |
| Benowitz NL | Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction. | 2008 | Clin. Pharmacol. Ther. | pmid:18305452 |
| Blackiston DJ et al. | Retention of memory through metamorphosis: can a moth remember what it learned as a caterpillar? | 2008 | PLoS ONE | pmid:18320055 |
| Fu SS et al. | Menthol cigarettes and smoking cessation during an aided quit attempt. | 2008 | Nicotine Tob. Res. | pmid:18324564 |
| Nomoto Y et al. | Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. | 2008 | Urology | pmid:18336880 |
| Ren MY et al. | pH memory of immobilized lipase for (+/-)-menthol resolution in ionic liquid. | 2008 | J. Agric. Food Chem. | pmid:18338863 |
| Wakai J et al. | Expression of Fos protein in brainstem after application of l-menthol to the rat nasal mucosa. | 2008 | Neurosci. Lett. | pmid:18343574 |
| Ditrichova D et al. | Oral lichenoid lesions and allergy to dental materials. | 2007 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | pmid:18345274 |
| De Petrocellis L et al. | Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18354058 |
| Wasner G et al. | The effect of menthol on cold allodynia in patients with neuropathic pain. | 2008 | Pain Med | pmid:18366513 |
| Kim KY et al. | TRP-independent inhibition of the phospholipase C pathway by natural sensory ligands. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18371303 |
| pmid:18374930 | ||||
| Wang M et al. | Effect of ion-pairing and enhancers on scutellarin skin permeability. | 2008 | J. Pharm. Pharmacol. | pmid:18380914 |
| Ciftçi O et al. | Mentholated cigarette smoking induced alterations in left and right ventricular functions in chronic smokers. | 2008 | Anadolu Kardiyol Derg | pmid:18400631 |
| pmid:18410140 | ||||
| Kreslake JM et al. | The menthol smoker: tobacco industry research on consumer sensory perception of menthol cigarettes and its role in smoking behavior. | 2008 | Nicotine Tob. Res. | pmid:18418792 |
| Belmonte C and Viana F | Molecular and cellular limits to somatosensory specificity. | 2008 | Mol Pain | pmid:18419827 |
| Jiang C et al. | Bladder cooling reflex and external urethral sphincter activity in the anesthetized and awake guinea pig. | 2008 | Pflugers Arch. | pmid:18421472 |
| Richter P et al. | Small-group discussions on menthol cigarettes: listening to adult African American smokers in Atlanta, Georgia. | 2008 | Ethn Health | pmid:18425713 |
| Kenia P et al. | Does inhaling menthol affect nasal patency or cough? | 2008 | Pediatr. Pulmonol. | pmid:18435479 |
| Namer B et al. | Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury. | 2008 | Pain | pmid:18440147 |
| Sapra B et al. | Percutaneous permeation enhancement by terpenes: mechanistic view. | 2008 | AAPS J | pmid:18446512 |
| Krishnaiah YS et al. | Penetration-enhancing effect of ethanolic solution of menthol on transdermal permeation of ondansetron hydrochloride across rat epidermis. | 2008 | Drug Deliv | pmid:18446568 |
| Lavender V et al. | Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion. | 2008 | Biochem. J. | pmid:18452405 |
| Haught JM et al. | Hydroxyethyl starch-induced pruritus relieved by a combination of menthol and camphor. | 2008 | J. Am. Acad. Dermatol. | pmid:18455262 |
| Sabnis AS et al. | Human lung epithelial cells express a functional cold-sensing TRPM8 variant. | 2008 | Am. J. Respir. Cell Mol. Biol. | pmid:18458237 |