(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

Cross Reference

Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Uveitis, Posterior D015866 5 associated lipids
Endophthalmitis D009877 12 associated lipids
Pain D010146 64 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

Download all related citations
Per page 10 20 50 100 | Total 2230
Authors Title Published Journal PubMed Link
Jo CL et al. Tobacco products sold by Internet vendors following restrictions on flavors and light descriptors. 2015 Nicotine Tob. Res. pmid:25173777
Taberner FJ et al. The region adjacent to the C-end of the inner gate in transient receptor potential melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation. 2014 J. Biol. Chem. pmid:25157108
Brennan E et al. Are young people's beliefs about menthol cigarettes associated with smoking-related intentions and behaviors? 2015 Nicotine Tob. Res. pmid:25151661
Xu ZL et al. [Studies on the essential oils of flos Magnoliae]. 1989 Zhongguo Zhong Yao Za Zhi pmid:2512947
Zimmermann MH et al. Relighting behaviour among cigarette smokers seeking treatment: implications for tobacco treatment and policy. 2014 Int. J. Clin. Pract. pmid:25113663
Curtin GM et al. Measures of initiation and progression to increased smoking among current menthol compared to non-menthol cigarette smokers based on data from four U.S. government surveys. 2014 Regul. Toxicol. Pharmacol. pmid:25111576
pmid:25102409
Russin WA et al. Inhibition of rat mammary carcinogenesis by monoterpenoids. 1989 Carcinogenesis pmid:2509095
Patel R et al. Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a comparison with topical menthol. 2014 Pain pmid:25083927
pmid:25082831
Hu X et al. Effects of d-menthol stress on the growth of and microcystin release by the freshwater cyanobacterium Microcystis aeruginosa FACHB-905. 2014 Chemosphere pmid:25065786
pmid:25058909
pmid:25046841
pmid:25042313
Sulsky SI et al. Evaluating the association between menthol cigarette use and the likelihood of being a former versus current smoker. 2014 Regul. Toxicol. Pharmacol. pmid:25017361
Curtin GM et al. Patterns of menthol cigarette use among current smokers, overall and within demographic strata, based on data from four U.S. government surveys. 2014 Regul. Toxicol. Pharmacol. pmid:24997230
pmid:24993660
Kasza KA et al. Switching between menthol and nonmenthol cigarettes: findings from the U.S. Cohort of the International Tobacco Control Four Country Survey. 2014 Nicotine Tob. Res. pmid:24984878
pmid:24965379
Chen GY et al. [Decreased amplitude of [Ca²⁺]i elevation induced by menthol in pulmonary arterial smooth muscle cells of pulmonary hypertensive rats]. 2014 Sheng Li Xue Bao pmid:24964842
Low SB et al. Evaluation of a topical gel containing a novel combination of essential oils and antioxidants for reducing oral malodor in dogs. 2014 Am. J. Vet. Res. pmid:24959732
pmid:24945417
Minaker LM et al. Flavored tobacco use among Canadian students in grades 9 through 12: prevalence and patterns from the 2010-2011 youth smoking survey. 2014 Prev Chronic Dis pmid:24945240
Smith SS et al. Smoking cessation in smokers who smoke menthol and non-menthol cigarettes. 2014 Addiction pmid:24938369
pmid:24935863
Kobal G et al. Is there directional smelling? 1989 Experientia pmid:2493388
Ribeiro JC et al. Efficacy of free and nanoencapsulated Eucalyptus citriodora essential oils on sheep gastrointestinal nematodes and toxicity for mice. 2014 Vet. Parasitol. pmid:24929446
Pertusa M et al. Bidirectional modulation of thermal and chemical sensitivity of TRPM8 channels by the initial region of the N-terminal domain. 2014 J. Biol. Chem. pmid:24917670
pmid:24913782
pmid:24874947
Curtin GM et al. Primary measures of dependence among menthol compared to non-menthol cigarette smokers in the United States. 2014 Regul. Toxicol. Pharmacol. pmid:24852490
pmid:24844622
Maurer F et al. Wash-out of ambient air contaminations for breath measurements. 2014 J Breath Res pmid:24837657
pmid:24832648
Cheyne A et al. The debate on regulating menthol cigarettes: closing a dangerous loophole vs freedom of choice. 2014 Am J Public Health pmid:24832437
da Silveira NS et al. The aversive, anxiolytic-like, and verapamil-sensitive psychostimulant effects of pulegone. 2014 Biol. Pharm. Bull. pmid:24790000
Mizuno K et al. Goshajinkigan, a traditional Japanese medicine, prevents oxaliplatin-induced acute peripheral neuropathy by suppressing functional alteration of TRP channels in rat. 2014 J. Pharmacol. Sci. pmid:24784702
Lewis M et al. Tobacco control environment in the United States and individual consumer characteristics in relation to continued smoking: differential responses among menthol smokers? 2014 Prev Med pmid:24780527
pmid:24777959
Klein AH et al. Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses. 2014 Neuroscience pmid:24759772
Frost-Pineda K et al. Predictors, indicators, and validated measures of dependence in menthol smokers. 2014 J Addict Dis pmid:24738914
pmid:24708203
pmid:24695880
Menger DJ et al. A push-pull system to reduce house entry of malaria mosquitoes. 2014 Malar. J. pmid:24674451
pmid:24664788
Parikh-Das AM et al. Superiority of essential oils versus 0.075% CPC-containing mouthrinse: a two-week randomized clinical trial. 2013 J Clin Dent pmid:24660271
Shang L et al. An explanation for the difference in the percutaneous penetration behavior of tamsulosin induced by two different O-acylmenthol derivatives. 2014 AAPS PharmSciTech pmid:24659001
pmid:24658318
Kijpornyongpan T et al. Dose-dependent cytotoxic effects of menthol on human malignant melanoma A-375 cells: correlation with TRPM8 transcript expression. 2014 Asian Pac. J. Cancer Prev. pmid:24641366
Bolcic-Jankovic D and Biener L Public opinion about FDA regulation of menthol and nicotine. 2015 Tob Control pmid:24638964
Sun J et al. Activation of cold-sensing transient receptor potential melastatin subtype 8 antagonizes vasoconstriction and hypertension through attenuating RhoA/Rho kinase pathway. 2014 Hypertension pmid:24637663
Rostron B Menthol cigarette use and stroke risk among US smokers: a critical reappraisal. 2014 JAMA Intern Med pmid:24614962
Iovinella I et al. A rationale to design longer lasting mosquito repellents. 2014 Parasitol. Res. pmid:24599300
pmid:24594507
pmid:24584277
pmid:24582134
Míguez-Burbano MJ et al. Menthol cigarettes and the cardiovascular risks of people living with HIV. 2014 Sep-Oct J Assoc Nurses AIDS Care pmid:24581861
pmid:24573731
Teliban A et al. Responses of intact and injured sural nerve fibers to cooling and menthol. 2014 J. Neurophysiol. pmid:24572095
Anderson EM et al. The effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment device. 2014 PLoS ONE pmid:24558480
Barkin RL The pharmacology of topical analgesics. 2013 Postgrad Med pmid:24547599
Wackowski OA et al. Young adults' behavioral intentions surrounding a potential menthol cigarette ban. 2014 Nicotine Tob. Res. pmid:24514070
Mahboubi M et al. Antimicrobial activity of natural Respitol-B and its main components against poultry microorganisms. 2013 Pak. J. Biol. Sci. pmid:24502173
Terada Y et al. Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree. 2014 J. Nat. Prod. pmid:24484240
Rozza AL et al. The gastroprotective effect of menthol: involvement of anti-apoptotic, antioxidant and anti-inflammatory activities. 2014 PLoS ONE pmid:24466200
Lau BK et al. Menthol enhances phasic and tonic GABAA receptor-mediated currents in midbrain periaqueductal grey neurons. 2014 Br. J. Pharmacol. pmid:24460753
pmid:24459687
Zhu S et al. Involvement of transient receptor potential melastatin-8 (TRPM8) in menthol-induced calcium entry, reactive oxygen species production and cell death in rheumatoid arthritis rat synovial fibroblasts. 2014 Eur. J. Pharmacol. pmid:24440691
Swandulla D et al. Effect of menthol on two types of Ca currents in cultured sensory neurons of vertebrates. 1987 Pflugers Arch. pmid:2441355
Persaud KC et al. Ion transport across the frog olfactory mucosa: the basal and odorant-stimulated states. 1987 Biochim. Biophys. Acta pmid:2440480
Azagba S and Sharaf MF Binge drinking and marijuana use among menthol and non-menthol adolescent smokers: findings from the youth smoking survey. 2014 Addict Behav pmid:24369112
Reinsperger T and Luy B Homonuclear BIRD-decoupled spectra for measuring one-bond couplings with highest resolution: CLIP/CLAP-RESET and constant-time-CLIP/CLAP-RESET. 2014 J. Magn. Reson. pmid:24365099
Feder-Kubis J and Bryjak J Laccase activity and stability in the presence of menthol-based ionic liquids. 2013 Acta Biochim. Pol. pmid:24364047
Tsumura M et al. Functional expression of TRPM8 and TRPA1 channels in rat odontoblasts. 2013 PLoS ONE pmid:24358160
Eccles R et al. The effect of aromatics on inspiratory and expiratory nasal resistance to airflow. 1987 Clin Otolaryngol Allied Sci pmid:2435435
Schäfer K et al. [Analysis of sensory transducer processes of peripheral cold receptors]. 1987 DTW. Dtsch. Tierarztl. Wochenschr. pmid:2434297
Rossato M et al. Human white adipocytes express the cold receptor TRPM8 which activation induces UCP1 expression, mitochondrial activation and heat production. 2014 Mol. Cell. Endocrinol. pmid:24342393
pmid:24335479
Mirokuji Y et al. The JFFMA assessment of flavoring substances structurally related to menthol and uniquely used in Japan. 2014 Food Chem. Toxicol. pmid:24309148
Schmidt SH and Hellström S Late effects of local anesthetics on tympanic membrane structure. 1986 Sep-Oct Am J Otolaryngol pmid:2430483
Swandulla D et al. Calcium channel current inactivation is selectively modulated by menthol. 1986 Neurosci. Lett. pmid:2425308
Li S et al. Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cells. 2013 Bioorg. Med. Chem. Lett. pmid:24210499
Jones MR et al. Smoking, menthol cigarettes and all-cause, cancer and cardiovascular mortality: evidence from the National Health and Nutrition Examination Survey (NHANES) and a meta-analysis. 2013 PLoS ONE pmid:24205038
Acharya SA et al. Hydrogel-stabilized droplet bilayers for high speed solution exchange. 2013 Sci Rep pmid:24190577
Familusi JB and Dawodu AH A survey of neonatal jaundice in association with household drugs and chemicals in Nigeria. 1985 Ann Trop Paediatr pmid:2418773
Jiang J et al. Mechanistic investigation and reversible effect of 2-isopropyl-5-methylcyclohexyl heptanoate on the in vitro percutaneous absorption of indomethacin. 2014 Drug Deliv pmid:24134638
Vetter I et al. Amplified cold transduction in native nociceptors by M-channel inhibition. 2013 J. Neurosci. pmid:24133266
Rozza AL et al. Effect of menthol in experimentally induced ulcers: pathways of gastroprotection. 2013 Chem. Biol. Interact. pmid:24121185
Rojewski AM et al. Menthol cigarette use predicts treatment outcomes of weight-concerned smokers. 2014 Nicotine Tob. Res. pmid:24113927
Ostacolo C et al. Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists. 2013 Eur J Med Chem pmid:24095758
Alpizar YA et al. Lack of correlation between the amplitudes of TRP channel-mediated responses to weak and strong stimuli in intracellular Ca(2+) imaging experiments. 2013 Cell Calcium pmid:24079971
Winhusen TM et al. A tale of two stimulants: mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence. 2013 Drug Alcohol Depend pmid:24075226
Moreland-Russell S et al. Disparities and menthol marketing: additional evidence in support of point of sale policies. 2013 Int J Environ Res Public Health pmid:24071922
Chen J et al. Species differences and molecular determinant of TRPA1 cold sensitivity. 2013 Nat Commun pmid:24071625
Kamatou GP et al. Menthol: a simple monoterpene with remarkable biological properties. 2013 Phytochemistry pmid:24054028
Amato A et al. Tetrodotoxin-dependent effects of menthol on mouse gastric motor function. 2013 Eur. J. Pharmacol. pmid:24041922
Chen H et al. A combination of site-directed mutagenesis and chemical modification to improve diastereopreference of Pseudomonas alcaligenes lipase. 2013 Biochim. Biophys. Acta pmid:24012560
Bhattacharjee AK In silico stereo-electronic analysis of PMD (p-Menthane-3-8-Diol) and its derivatives for pharmacophore development may aid discovery of novel insect repellents. 2013 Curr Comput Aided Drug Des pmid:24010930
pmid:23997070
Reitzel LR et al. Associations of menthol use with motivation and confidence to quit smoking. 2013 Am J Health Behav pmid:23985285