(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Katotomichelakis M et al. Recurrent prurigo nodularis related to infected tonsils: a case report. 2008 J Med Case Rep pmid:18652691
pmid:18649219
Orani GP et al. Upper airway cooling and l-menthol reduce ventilation in the guinea pig. 1991 J. Appl. Physiol. pmid:1864790
Ito S et al. Inhibition by the cold receptor agonists menthol and icilin of airway smooth muscle contraction. 2008 Pulm Pharmacol Ther pmid:18647657
Mendelson JE et al. The clinical pharmacology of intranasal l-methamphetamine. 2008 BMC Clin Pharmacol pmid:18644153
Bhatia SP et al. Fragrance material review on l-menthol. 2008 Food Chem. Toxicol. pmid:18640225
Bhatia SP et al. Fragrance material review on 4-carvomenthenol. 2008 Food Chem. Toxicol. pmid:18640221
Bhatia SP et al. Fragrance material review on d-menthol. 2008 Food Chem. Toxicol. pmid:18640220
Bhatia SP et al. Fragrance material review on d,l-menthol. 2008 Food Chem. Toxicol. pmid:18640200
Bhatia SP et al. Fragrance material review on menthol racemic. 2008 Food Chem. Toxicol. pmid:18640189
Bhatia SP et al. Fragrance material review on menthol. 2008 Food Chem. Toxicol. pmid:18640186
Bhatia SP et al. Fragrance material review on geranodyle. 2008 Food Chem. Toxicol. pmid:18640183
Malta E et al. Functions of base flipping in E. coli nucleotide excision repair. 2008 DNA Repair (Amst.) pmid:18638572
Kreslake JM et al. Tobacco industry control of menthol in cigarettes and targeting of adolescents and young adults. 2008 Am J Public Health pmid:18633084
Ernsberger U The role of GDNF family ligand signalling in the differentiation of sympathetic and dorsal root ganglion neurons. 2008 Cell Tissue Res. pmid:18629541
Seo KA et al. The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity. 2008 Chem. Biol. Interact. pmid:18611395
Shimizu K et al. Essential oil of lavender inhibited the decreased attention during a long-term task in humans. 2008 Biosci. Biotechnol. Biochem. pmid:18603803
Choi HW et al. A role for a menthone reductase in resistance against microbial pathogens in plants. 2008 Plant Physiol. pmid:18599651
Watt EE et al. Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol. 2008 Eur. J. Pharmacol. pmid:18593637
Tokuoka Y et al. Enhancement in skin permeation of 5-aminolevulinic acid using l-menthol and its derivatives. 2008 Drug Dev Ind Pharm pmid:18568909
Xing H et al. TRPM8 mechanism of autonomic nerve response to cold in respiratory airway. 2008 Mol Pain pmid:18534015
Yamamura H et al. TRPM8 activation suppresses cellular viability in human melanoma. 2008 Am. J. Physiol., Cell Physiol. pmid:18524940
Rollison DE et al. Case-control study of tobacco smoke exposure and breast cancer risk in Delaware. 2008 BMC Cancer pmid:18518960
Wondergem R et al. HGF/SF and menthol increase human glioblastoma cell calcium and migration. 2008 Biochem. Biophys. Res. Commun. pmid:18485891
Schäfer K et al. Discharge pattern analysis suggests existence of a low-threshold calcium channel in cold receptors. 1991 Experientia pmid:1847881
Kozyreva TV and Tkachenko EIa [Effect of menthol on human temperature sensitivity]. 2008 Mar-Apr Fiziol Cheloveka pmid:18472579
Ciftci O et al. Smoking mentholated cigarettes impairs coronary microvascular function as severely as does smoking regular cigarettes. 2008 Acta Cardiol pmid:18468190
Moennikes O et al. Reduced toxicological activity of cigarette smoke by the addition of ammonia magnesium phosphate to the paper of an electrically heated cigarette: subchronic inhalation toxicology. 2008 Inhal Toxicol pmid:18464053
Rudick CN et al. Mast cell-derived histamine mediates cystitis pain. 2008 PLoS ONE pmid:18461160
Stotz SC et al. Citral sensing by Transient [corrected] receptor potential channels in dorsal root ganglion neurons. 2008 PLoS ONE pmid:18461159
Sabnis AS et al. Human lung epithelial cells express a functional cold-sensing TRPM8 variant. 2008 Am. J. Respir. Cell Mol. Biol. pmid:18458237
Haught JM et al. Hydroxyethyl starch-induced pruritus relieved by a combination of menthol and camphor. 2008 J. Am. Acad. Dermatol. pmid:18455262
Lavender V et al. Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion. 2008 Biochem. J. pmid:18452405
Krishnaiah YS et al. Penetration-enhancing effect of ethanolic solution of menthol on transdermal permeation of ondansetron hydrochloride across rat epidermis. 2008 Drug Deliv pmid:18446568
Sapra B et al. Percutaneous permeation enhancement by terpenes: mechanistic view. 2008 AAPS J pmid:18446512
Namer B et al. Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury. 2008 Pain pmid:18440147
Kenia P et al. Does inhaling menthol affect nasal patency or cough? 2008 Pediatr. Pulmonol. pmid:18435479
Richter P et al. Small-group discussions on menthol cigarettes: listening to adult African American smokers in Atlanta, Georgia. 2008 Ethn Health pmid:18425713
Jiang C et al. Bladder cooling reflex and external urethral sphincter activity in the anesthetized and awake guinea pig. 2008 Pflugers Arch. pmid:18421472
Belmonte C and Viana F Molecular and cellular limits to somatosensory specificity. 2008 Mol Pain pmid:18419827
Kreslake JM et al. The menthol smoker: tobacco industry research on consumer sensory perception of menthol cigarettes and its role in smoking behavior. 2008 Nicotine Tob. Res. pmid:18418792
pmid:18410140
Ciftçi O et al. Mentholated cigarette smoking induced alterations in left and right ventricular functions in chronic smokers. 2008 Anadolu Kardiyol Derg pmid:18400631
Wang M et al. Effect of ion-pairing and enhancers on scutellarin skin permeability. 2008 J. Pharm. Pharmacol. pmid:18380914
pmid:18374930
Kim KY et al. TRP-independent inhibition of the phospholipase C pathway by natural sensory ligands. 2008 Biochem. Biophys. Res. Commun. pmid:18371303
Wasner G et al. The effect of menthol on cold allodynia in patients with neuropathic pain. 2008 Pain Med pmid:18366513
De Petrocellis L et al. Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. 2008 J. Pharmacol. Exp. Ther. pmid:18354058
Ditrichova D et al. Oral lichenoid lesions and allergy to dental materials. 2007 Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub pmid:18345274
Wakai J et al. Expression of Fos protein in brainstem after application of l-menthol to the rat nasal mucosa. 2008 Neurosci. Lett. pmid:18343574
Ren MY et al. pH memory of immobilized lipase for (+/-)-menthol resolution in ionic liquid. 2008 J. Agric. Food Chem. pmid:18338863
Nomoto Y et al. Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. 2008 Urology pmid:18336880
Fu SS et al. Menthol cigarettes and smoking cessation during an aided quit attempt. 2008 Nicotine Tob. Res. pmid:18324564
Blackiston DJ et al. Retention of memory through metamorphosis: can a moth remember what it learned as a caterpillar? 2008 PLoS ONE pmid:18320055
Benowitz NL Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction. 2008 Clin. Pharmacol. Ther. pmid:18305452
Mu TW et al. Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis. 2008 PLoS Biol. pmid:18254660
pmid:18251800
pmid:18247142
Brady D et al. Spherezymes: a novel structured self-immobilisation enzyme technology. 2008 BMC Biotechnol. pmid:18237402
Dussor G et al. Cutaneous sensory neurons expressing the Mrgprd receptor sense extracellular ATP and are putative nociceptors. 2008 J. Neurophysiol. pmid:18234974
Nassenstein C et al. Expression and function of the ion channel TRPA1 in vagal afferent nerves innervating mouse lungs. 2008 J. Physiol. (Lond.) pmid:18218683
pmid:18215479
Haas AL et al. Cigarette smoking in opioid-using patients presenting for hospital-based medical services. 2008 Jan-Feb Am J Addict pmid:18214725
Meseguer V et al. Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole. 2008 J. Neurosci. pmid:18199759
Dhaka A et al. Visualizing cold spots: TRPM8-expressing sensory neurons and their projections. 2008 J. Neurosci. pmid:18199758
pmid:18197139
Macfarlane JT and Worboys M The changing management of acute bronchitis in Britain, 1940-1970: the impact of antibiotics. 2008 Med Hist pmid:18180811
pmid:18177050
pmid:18142290
Yano T et al. Effects of l-menthol and dl-camphor on the penetration and hydrolysis of methyl salicylate in hairless mouse skin. 1991 J. Pharmacobio-dyn. pmid:1812275
ANDRADE MA [Differential reactions of camphor, menthol and terpene hydrated]. 1948 Sep-Dec J Farm pmid:18119741
Samarasekera R et al. Insecticidal activity of menthol derivatives against mosquitoes. 2008 Pest Manag. Sci. pmid:18095385
Takashima Y et al. Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons. 2007 J. Neurosci. pmid:18094254
Petrus M et al. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. 2007 Mol Pain pmid:18086313
Kondrats'kyÄ­ AP et al. [Functional identification of the TRPM8 cold receptor in rat prostate epithelial cells]. 2007 Fiziol Zh pmid:18080488
Ohshima T et al. Highly Enantio- and s-trans C=C bond selective catalytic hydrogenation of cyclic enones: alternative synthesis of (-)-menthol. 2008 Chemistry pmid:18080262
Loi RX et al. Solid-phase microextraction method for in vivo measurement of allelochemical uptake. 2008 J. Chem. Ecol. pmid:18080164
Xing H et al. TRPM8 mechanism of cold allodynia after chronic nerve injury. 2007 J. Neurosci. pmid:18077679
pmid:18065850
Zhao L et al. Transdermal delivery of penetrants with differing lipophilicities using O-acylmenthol derivatives as penetration enhancers. 2008 Eur J Pharm Biopharm pmid:18065216
Zanotto KL et al. Cross-desensitization of responses of rat trigeminal subnucleus caudalis neurons to cinnamaldehyde and menthol. 2008 Neurosci. Lett. pmid:18060696
Zhao L et al. Effect of O-acylmenthol on transdermal delivery of drugs with different lipophilicity. 2008 Int J Pharm pmid:18053661
McDaniel PA and Malone RE "I always thought they were all pure tobacco": American smokers' perceptions of "natural" cigarettes and tobacco industry advertising strategies. 2007 Tob Control pmid:18048597
Dambolena JS et al. Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. 2008 Toxicon pmid:18037463
Deluc LG et al. Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development. 2007 BMC Genomics pmid:18034876
Julius D From peppers to peppermints: natural products as probes of the pain pathway. 2005-2006 Harvey Lect. pmid:18030977
pmid:18022442
Carballeira JD et al. High throughput screening and QSAR-3D/CoMFA: useful tools to design predictive models of substrate specificity for biocatalysts. 2004 Molecules pmid:18007469
Aulenta F et al. Fragrance release from the surface of branched poly (amide)s. 2005 Molecules pmid:18007278
pmid:17994363
Naito K et al. The effect of L-menthol stimulation of the major palatine nerve on nasal patency. 1991 Auris Nasus Larynx pmid:1799329
Herkenne C et al. In vivo methods for the assessment of topical drug bioavailability. 2008 Pharm. Res. pmid:17985216
Yamasaki M et al. Cough reflex and oral chemesthesis induced by capsaicin and capsiate in healthy never-smokers. 2007 Cough pmid:17971242
Tiemann P et al. Administration of Ratanhia-based herbal oral care products for the prophylaxis of oral mucositis in cancer chemotherapy patients: a clinical trial. 2007 Evid Based Complement Alternat Med pmid:17965768
Olivella MS et al. Effects of dimethylformamide and L-menthol permeation enhancers on transdermal delivery of quercetin. 2007 Pharm Dev Technol pmid:17963148
Shapira R and Mimran E Isolation and characterization of Escherichia coli mutants exhibiting altered response to thymol. 2007 Microb. Drug Resist. pmid:17949301
Ulmer WT and Schött D [Chronic obstructive bronchitis. Effect of Gelomyrtol forte in a placebo-controlled double-blind study]. 1991 Fortschr. Med. pmid:1794831
Hayashi S et al. Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer. 2007 Inflammopharmacology pmid:17943255
Matta JA and Ahern GP Voltage is a partial activator of rat thermosensitive TRP channels. 2007 J. Physiol. (Lond.) pmid:17932142
Okuyemi KS et al. Relationship between menthol cigarettes and smoking cessation among African American light smokers. 2007 Addiction pmid:17916223