| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Uveitis, Posterior | D015866 | 5 associated lipids |
Total
3
(-)-Menthol
(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.
Cross Reference
Introduction
To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Menthol?
(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Menthol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Menthol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Menthol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (-)-Menthol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Menthol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (-)-Menthol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Menthol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Menthol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mitka M | FDA might consider restrictions on menthol cigarettes. | 2013 | JAMA | pmid:23982355 |
| Dolka C et al. | Menthol addition to cigarettes using breakable capsules in the filter. Impact on the mainstream smoke yields of the health Canada list constituents. | 2013 | Chem. Res. Toxicol. | pmid:23978141 |
| Ashoor A et al. | Menthol inhibits 5-HT3 receptor-mediated currents. | 2013 | J. Pharmacol. Exp. Ther. | pmid:23965380 |
| pmid:23963768 | ||||
| Yang B et al. | [Study on pharmacokinetics and in vitro/in vivo correlation of menthol in Zhike Chuanbei Pipa dropping pills in rats]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23944081 |
| Ashoor A et al. | Menthol binding and inhibition of α7-nicotinic acetylcholine receptors. | 2013 | PLoS ONE | pmid:23935840 |
| Zhang Y et al. | Effects of caffeine and menthol on cognition and mood during simulated firefighting in the heat. | 2014 | Appl Ergon | pmid:23891504 |
| Kong G et al. | Menthol cigarette and marijuana use among adolescents. | 2013 | Nicotine Tob. Res. | pmid:23884319 |
| Tang Z et al. | Pirt functions as an endogenous regulator of TRPM8. | 2013 | Nat Commun | pmid:23863968 |
| Selescu T et al. | Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin. | 2013 | Chem. Senses | pmid:23828908 |
| Vahabi B et al. | TRPM8 agonists modulate contraction of the pig urinary bladder. | 2013 | Can. J. Physiol. Pharmacol. | pmid:23826977 |
| Liu B et al. | TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain. | 2013 | Pain | pmid:23820004 |
| Liu XR et al. | Down-regulation of TRPM8 in pulmonary arteries of pulmonary hypertensive rats. | 2013 | Cell. Physiol. Biochem. | pmid:23817166 |
| Ngo-Thi MT et al. | Enantioselective hydrolysis of dl-menthyl benzoate by cell-free extract of newly isolated Acinetobacter sp. ECU2040. | 2013 | Appl. Biochem. Biotechnol. | pmid:23801098 |
| pmid:23800946 | ||||
| Sharara AI et al. | Sugar-free menthol candy drops improve the palatability and bowel cleansing effect of polyethylene glycol electrolyte solution. | 2013 | Gastrointest. Endosc. | pmid:23769143 |
| Zuo X et al. | Operant behavioral responses to orofacial cold stimuli in rats with chronic constrictive trigeminal nerve injury: effects of menthol and capsazepine. | 2013 | Mol Pain | pmid:23767981 |
| Ali MS et al. | In vitro antioxidant, cytotoxic, thrombolytic activities and phytochemical evaluation of methanol extract of the A. philippense L. leaves. | 2013 | Asian Pac J Trop Biomed | pmid:23730559 |
| Flores-Rizo JO et al. | 8-Alkoxy- and 8-aryloxy-BODIPYs: straightforward fluorescent tagging of alcohols and phenols. | 2013 | J. Org. Chem. | pmid:23721096 |
| SantamarÃa E et al. | [Field efficacy of repellent formulation containing para-menthane-3,8-diol and lemongrass against Culicoides pachymerus (Diptera: Ceratopogonidae) in Colombia]. | 2012 | Biomedica | pmid:23715194 |
| Zakariasen KL et al. | Efficient and effective root canal retreatment without chloroform. | 1990 | J Can Dent Assoc | pmid:2369702 |
| Topp R et al. | Topical menthol, ice, peripheral blood flow, and perceived discomfort. | 2013 Mar-Apr | J Athl Train | pmid:23672386 |
| Kaffenberger RM and Doyle MJ | Determination of menthol and menthol glucuronide in human urine by gas chromatography using an enzyme-sensitive internal standard and flame ionization detection. | 1990 | J. Chromatogr. | pmid:2365793 |
| Plevkova J et al. | The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol. | 2013 | J. Appl. Physiol. | pmid:23640596 |
| Kurose M and Meng ID | Dry eye modifies the thermal and menthol responses in rat corneal primary afferent cool cells. | 2013 | J. Neurophysiol. | pmid:23636717 |
| Radu CD et al. | Cotton-made cellulose support for anti-allergic pajamas. | 2013 | Carbohydr Polym | pmid:23618296 |
| Bose SK et al. | Effect of gibberellic acid and calliterpenone on plant growth attributes, trichomes, essential oil biosynthesis and pathway gene expression in differential manner in Mentha arvensis L. | 2013 | Plant Physiol. Biochem. | pmid:23514759 |
| Kosar E and Schwartz GJ | Effects of menthol on peripheral nerve and cortical unit responses to thermal stimulation of the oral cavity in the rat. | 1990 | Brain Res. | pmid:2350690 |
| Villanti AC et al. | Flavored tobacco product use among U.S. young adults. | 2013 | Am J Prev Med | pmid:23498105 |
| Chooluck K et al. | Plasma and dermal pharmacokinetics of terpinen-4-ol in rats following intravenous administration. | 2013 | Pharmazie | pmid:23469686 |
| Pereira EJ et al. | The effect of inhaled menthol on upper airway resistance in humans: a randomized controlled crossover study. | 2013 Jan-Feb | Can. Respir. J. | pmid:23457678 |
| Jiao HY et al. | [GC-MS study on fingerprint of volatile oil from Kadsura heteroclita]. | 2012 | Zhong Yao Cai | pmid:23451498 |
| Rajput SB and Karuppayil SM | Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans. | 2013 | Springerplus | pmid:23449869 |
| Gillissen A et al. | A multi-centre, randomised, double-blind, placebo-controlled clinical trial on the efficacy and tolerability of GeloMyrtol® forte in acute bronchitis. | 2013 | Drug Res (Stuttg) | pmid:23447044 |
| Kurose M and Meng ID | Corneal dry-responsive neurons in the spinal trigeminal nucleus respond to innocuous cooling in the rat. | 2013 | J. Neurophysiol. | pmid:23446686 |
| Nuisin R et al. | Microencapsulation of menthol by crosslinked chitosan via porous glass membrane emulsification technique and their controlled release properties. | 2013 | J Microencapsul | pmid:23398357 |
| Thomassen D et al. | Menthofuran-dependent and independent aspects of pulegone hepatotoxicity: roles of glutathione. | 1990 | J. Pharmacol. Exp. Ther. | pmid:2338648 |
| Cheang WS et al. | Menthol relaxes rat aortae, mesenteric and coronary arteries by inhibiting calcium influx. | 2013 | Eur. J. Pharmacol. | pmid:23380688 |
| Wang T et al. | Neurturin overexpression in skin enhances expression of TRPM8 in cutaneous sensory neurons and leads to behavioral sensitivity to cool and menthol. | 2013 | J. Neurosci. | pmid:23365243 |
| Macfoy CA and Cline EI | In vitro antibacterial activities of three plants used in traditional medicine in Sierra Leone. | 1990 | J Ethnopharmacol | pmid:2335960 |
| O'Mullane LM et al. | Co-cultures provide a new tool to probe communication between adult sensory neurons and urothelium. | 2013 | J. Urol. | pmid:23353045 |
| Kawasaki H et al. | Inhibition by menthol and its related chemicals of compound action potentials in frog sciatic nerves. | 2013 | Life Sci. | pmid:23352972 |
| Strasser AA et al. | The effect of menthol on cigarette smoking behaviors, biomarkers and subjective responses. | 2013 | Cancer Epidemiol. Biomarkers Prev. | pmid:23334588 |
| Chen Y et al. | Effect of unsaturated menthol analogues on the in vitro penetration of 5-fluorouracil through rat skin. | 2013 | Int J Pharm | pmid:23333756 |
| Lu S et al. | Somatosensory profiling of intra-oral capsaicin and menthol in healthy subjects. | 2013 | Eur. J. Oral Sci. | pmid:23331421 |
| Kurohane K et al. | Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice. | 2013 | Toxicol. Lett. | pmid:23296101 |
| Rostron B | Methodology, menthol, and mortality. | 2013 | Nicotine Tob. Res. | pmid:23291639 |
| Reitzel LR et al. | Race moderates the effect of menthol cigarette use on short-term smoking abstinence. | 2013 | Nicotine Tob. Res. | pmid:23288873 |
| Bharti N et al. | The greater effectiveness of Glomus mosseae and Glomus intraradices in improving productivity, oil content and tolerance of salt-stressed menthol mint (Mentha arvensis). | 2013 | J. Sci. Food Agric. | pmid:23288591 |
| Carter L | Commentary on Nonnemaker et al. (2013): Banning menthol cigarettes - is it time to conduct the experiment? | 2013 | Addiction | pmid:23279359 |
| Maji D et al. | A natural plant growth promoter calliterpenone from a plant Callicarpa macrophylla Vahl improves the plant growth promoting effects of plant growth promoting rhizobacteria (PGPRs). | 2013 | World J. Microbiol. Biotechnol. | pmid:23271460 |
| Vase L et al. | The effects of menthol on cold allodynia and wind-up-like pain in upper limb amputees with different levels of phantom limb pain. | 2013 | Neurosci. Lett. | pmid:23266475 |
| Millqvist E et al. | Inhalation of menthol reduces capsaicin cough sensitivity and influences inspiratory flows in chronic cough. | 2013 | Respir Med | pmid:23266255 |
| Kashima H and Hayashi N | Facial skin blood flow responses to irritant stimuli in the oral cavity. | 2013 | Auton Neurosci | pmid:23265982 |
| Abdullah GZ et al. | Carbopol 934, 940 and Ultrez 10 as viscosity modifiers of palm olein esters based nano-scaled emulsion containing ibuprofen. | 2013 | Pak J Pharm Sci | pmid:23261730 |
| Valero ML et al. | TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells. | 2012 | PLoS ONE | pmid:23251635 |
| Jones MR et al. | Menthol cigarettes, race/ethnicity, and biomarkers of tobacco use in U.S. adults: the 1999-2010 National Health and Nutrition Examination Survey (NHANES). | 2013 | Cancer Epidemiol. Biomarkers Prev. | pmid:23250935 |
| [Bronchitis and sinusitis. Effective treatment by stimulating mucociliary clearance]. | 2012 | MMW Fortschr Med | pmid:23234125 | |
| Eccles R et al. | The effects of menthol on reaction time and nasal sensation of airflow in subjects suffering from the common cold. | 1990 | Clin Otolaryngol Allied Sci | pmid:2323078 |
| Jones MR et al. | Smoking, menthol cigarettes, and peripheral artery disease in U.S. adults. | 2013 | Nicotine Tob. Res. | pmid:23212436 |
| Kolassa N | Menthol differs from other terpenic essential oil constituents. | 2013 | Regul. Toxicol. Pharmacol. | pmid:23207345 |
| Takaishi M et al. | 1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1. | 2012 | Mol Pain | pmid:23192000 |
| Brody AL et al. | Up-regulation of nicotinic acetylcholine receptors in menthol cigarette smokers. | 2013 | Int. J. Neuropsychopharmacol. | pmid:23171716 |
| Wilson MD et al. | Efficacy of DEET and non-DEET-based insect repellents against bites of Simulium damnosum vectors of onchocerciasis. | 2013 | Med. Vet. Entomol. | pmid:23167529 |
| Journigan VB and Zaveri NT | TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology. | 2013 | Life Sci. | pmid:23159643 |
| Tanabe A et al. | Effects of corticotropin-releasing factor on intermediolateral cell column neurons of newborn rats. | 2012 | Auton Neurosci | pmid:23151516 |
| Sarkar M et al. | Metabolism of nicotine and 4-(methylnitrosamino)-l-(3-pyridyl)-lbutanone (NNK) in menthol and non-menthol cigarette smokers. | 2012 | Drug Metab Lett | pmid:23140558 |
| Averbeck B et al. | Thermal grill-evoked sensations of heat correlate with cold pain threshold and are enhanced by menthol and cinnamaldehyde. | 2013 | Eur J Pain | pmid:23138876 |
| Motilal S and Maharaj RG | Nutmeg extracts for painful diabetic neuropathy: a randomized, double-blind, controlled study. | 2013 | J Altern Complement Med | pmid:23098698 |
| Voets T et al. | Transient receptor potential channel promiscuity frustrates constellation pharmacology. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23093678 |
| pmid:23089487 | ||||
| D'Silva J et al. | Cessation outcomes among treatment-seeking menthol and nonmenthol smokers. | 2012 | Am J Prev Med | pmid:23079223 |
| Farco JA and Grundmann O | Menthol--pharmacology of an important naturally medicinal "cool". | 2013 | Mini Rev Med Chem | pmid:23061635 |
| Nagamatsu R et al. | Cleavage of α-dicarbonyl compounds by terpene hydroperoxide. | 2012 | Biosci. Biotechnol. Biochem. | pmid:23047102 |
| Lachenmeier DW et al. | What happens if people start drinking mouthwash as surrogate alcohol? A quantitative risk assessment. | 2013 | Food Chem. Toxicol. | pmid:23041419 |
| Duangjit S et al. | Menthosomes, novel ultradeformable vesicles for transdermal drug delivery: optimization and characterization. | 2012 | Biol. Pharm. Bull. | pmid:23037161 |
| Wang JT et al. | Physiological and biochemical performances of menthol-induced aposymbiotic corals. | 2012 | PLoS ONE | pmid:23029512 |
| Marsh L et al. | A refreshing poison: one-quarter of young New Zealand smokers choose menthol. | 2012 | Aust N Z J Public Health | pmid:23025381 |
| Rostron B | Response to "menthol cigarettes and lung cancer mortality". | 2012 | Nicotine Tob. Res. | pmid:23012335 |
| Muscat JE | Menthol cigarettes and lung cancer mortality. | 2012 | Nicotine Tob. Res. | pmid:23012334 |
| Kang W et al. | Characterization of aroma compounds in Chinese bayberry (Myrica rubra Sieb. et Zucc.) by gas chromatography mass spectrometry (GC-MS) and olfactometry (GC-O). | 2012 | J. Food Sci. | pmid:23009608 |
| pmid:23001121 | ||||
| Aoki M et al. | Effect of synthetic eel calcitonin, elcatonin, on cold and mechanical allodynia induced by oxaliplatin and paclitaxel in rats. | 2012 | Eur. J. Pharmacol. | pmid:23001015 |
| Pearson JL et al. | A ban on menthol cigarettes: impact on public opinion and smokers' intention to quit. | 2012 | Am J Public Health | pmid:22994173 |
| Lin J et al. | Enhancement of gene transfer efficiency in the Bcap-37 cell line by dimethyl sulphoxide and menthol. | 2012 | Mol Med Rep | pmid:22992809 |
| Villanti AC et al. | Menthol cigarettes and mortality: keeping focus on the public health standard. | 2013 | Nicotine Tob. Res. | pmid:22990220 |
| Redasani VK and Bari SB | Synthesis and evaluation of mutual prodrugs of ibuprofen with menthol, thymol and eugenol. | 2012 | Eur J Med Chem | pmid:22982120 |
| Topp R et al. | The effect of either topical menthol or a placebo on functioning and knee pain among patients with knee OA. | 2013 Apr-Jun | J Geriatr Phys Ther | pmid:22976810 |
| Robbins A et al. | Menthol activation of corneal cool cells induces TRPM8-mediated lacrimation but not nociceptive responses in rodents. | 2012 | Invest. Ophthalmol. Vis. Sci. | pmid:22952122 |
| Pan R et al. | Central mechanisms of menthol-induced analgesia. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22951274 |
| Kweka EJ et al. | Protective efficacy of menthol propylene glycol carbonate compared to N, N-diethyl-methylbenzamide against mosquito bites in Northern Tanzania. | 2012 | Parasit Vectors | pmid:22950604 |
| Bertoli A et al. | In vitro production of M. × piperita not containing pulegone and menthofuran. | 2012 | Acta Biochim. Pol. | pmid:22946028 |
| pmid:22944434 | ||||
| Poston WS et al. | Menthol cigarette pricing at military and community retail outlets in the United States. | 2012 | BMC Public Health | pmid:22938755 |
| Shiba T et al. | Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22935519 |
| Hirata H et al. | Quantitative characterization reveals three types of dry-sensitive corneal afferents: pattern of discharge, receptive field, and thermal and chemical sensitivity. | 2012 | J. Neurophysiol. | pmid:22914652 |
| Nonnemaker J et al. | Initiation with menthol cigarettes and youth smoking uptake. | 2013 | Addiction | pmid:22862154 |
| Bharate SS and Bharate SB | Modulation of thermoreceptor TRPM8 by cooling compounds. | 2012 | ACS Chem Neurosci | pmid:22860192 |
| Szema AM and Barnett T | Allergic reaction to mint leads to asthma. | 2011 | Allergy Rhinol (Providence) | pmid:22852115 |
| Zhao M et al. | Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice. | 2012 | Mol Pain | pmid:22839205 |