(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Endophthalmitis D009877 12 associated lipids
Pain D010146 64 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Acharya SA et al. Hydrogel-stabilized droplet bilayers for high speed solution exchange. 2013 Sci Rep pmid:24190577
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Liu XR et al. Down-regulation of TRPM8 in pulmonary arteries of pulmonary hypertensive rats. 2013 Cell. Physiol. Biochem. pmid:23817166
Ngo-Thi MT et al. Enantioselective hydrolysis of dl-menthyl benzoate by cell-free extract of newly isolated Acinetobacter sp. ECU2040. 2013 Appl. Biochem. Biotechnol. pmid:23801098
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Kurose M and Meng ID Dry eye modifies the thermal and menthol responses in rat corneal primary afferent cool cells. 2013 J. Neurophysiol. pmid:23636717
Averbeck B et al. Thermal grill-evoked sensations of heat correlate with cold pain threshold and are enhanced by menthol and cinnamaldehyde. 2013 Eur J Pain pmid:23138876
Wilson MD et al. Efficacy of DEET and non-DEET-based insect repellents against bites of Simulium damnosum vectors of onchocerciasis. 2013 Med. Vet. Entomol. pmid:23167529
Brody AL et al. Up-regulation of nicotinic acetylcholine receptors in menthol cigarette smokers. 2013 Int. J. Neuropsychopharmacol. pmid:23171716
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Alpizar YA et al. Lack of correlation between the amplitudes of TRP channel-mediated responses to weak and strong stimuli in intracellular Ca(2+) imaging experiments. 2013 Cell Calcium pmid:24079971
Amato A et al. Tetrodotoxin-dependent effects of menthol on mouse gastric motor function. 2013 Eur. J. Pharmacol. pmid:24041922
Tang Z et al. Pirt functions as an endogenous regulator of TRPM8. 2013 Nat Commun pmid:23863968
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Barkin RL The pharmacology of topical analgesics. 2013 Postgrad Med pmid:24547599
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Winhusen TM et al. A tale of two stimulants: mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence. 2013 Drug Alcohol Depend pmid:24075226
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Okuyemi KS et al. Effects of menthol on the pharmacokinetics of bupropion among Black smokers. 2012 Nicotine Tob. Res. pmid:22318754
Abobo CV et al. Effect of menthol on nicotine pharmacokinetics in rats after cigarette smoke inhalation. 2012 Nicotine Tob. Res. pmid:22311961
Taylor R et al. A randomized, double-blind comparison shows the addition of oxygenated glycerol triesters to topical mentholated cream for the treatment of acute musculoskeletal pain demonstrates incremental benefit over time. 2012 Pain Pract pmid:22304620
Poston WS et al. Menthol cigarette pricing at military and community retail outlets in the United States. 2012 BMC Public Health pmid:22938755
Vozoris NT Mentholated cigarettes and cardiovascular and pulmonary diseases: a population-based study. 2012 Arch. Intern. Med. pmid:22493467
Renner B and Schreiber K Olfactory and trigeminal interaction of menthol and nicotine in humans. 2012 Exp Brain Res pmid:22434343
Wang Y et al. Menthol inhibits the proliferation and motility of prostate cancer DU145 cells. 2012 Pathol. Oncol. Res. pmid:22437241
Kabat GC et al. Mentholated cigarettes and smoking-related cancers revisited: an ecologic examination. 2012 Regul. Toxicol. Pharmacol. pmid:22429780
Klein AH et al. Topical hindpaw application of L-menthol decreases responsiveness to heat with biphasic effects on cold sensitivity of rat lumbar dorsal horn neurons. 2012 Neuroscience pmid:22687951
Valero ML et al. TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells. 2012 PLoS ONE pmid:23251635
Camele I et al. In vitro control of post-harvest fruit rot fungi by some plant essential oil components. 2012 Int J Mol Sci pmid:22408454
Muscat JE Menthol cigarettes and lung cancer mortality. 2012 Nicotine Tob. Res. pmid:23012334
Avrahami D et al. A randomized, placebo-controlled double-blinded comparative clinical study of five over-the-counter non-pharmacological topical analgesics for myofascial pain: single session findings. 2012 Chiropr Man Therap pmid:22436614
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Sanders E et al. Does the use of ingredients added to tobacco increase cigarette addictiveness?: a detailed analysis. 2012 Inhal Toxicol pmid:22429143
Marsh L et al. A refreshing poison: one-quarter of young New Zealand smokers choose menthol. 2012 Aust N Z J Public Health pmid:23025381
Yoshihara M and Ito K Acute genetic manipulation of neuronal activity for the functional dissection of neural circuits-a dream come true for the pioneers of behavioral genetics. 2012 J. Neurogenet. pmid:22420407
Wang JT et al. Physiological and biochemical performances of menthol-induced aposymbiotic corals. 2012 PLoS ONE pmid:23029512
Böhm M et al. Liposomes: a new non-pharmacological therapy concept for seasonal-allergic-rhinoconjunctivitis. 2012 Eur Arch Otorhinolaryngol pmid:21761190
Shiba T et al. Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model. 2012 Toxicol. Appl. Pharmacol. pmid:22935519
Hamoud R et al. Antimicrobial activity of a traditionally used complex essential oil distillate (Olbas(®) Tropfen) in comparison to its individual essential oil ingredients. 2012 Phytomedicine pmid:22739414