(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Uveitis, Posterior D015866 5 associated lipids
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Su L et al. Role of TRPM8 in dorsal root ganglion in nerve injury-induced chronic pain. 2011 BMC Neurosci pmid:22111979
Hirata H and Oshinsky ML Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels. 2012 J. Neurophysiol. pmid:22114162
Pupe CG et al. Preparation and evaluation of antimicrobial activity of nanosystems for the control of oral pathogens Streptococcus mutans and Candida albicans. 2011 Int J Nanomedicine pmid:22114490
Marcos-Arias C et al. In vitro activities of natural products against oral Candida isolates from denture wearers. 2011 BMC Complement Altern Med pmid:22118215
Ebihara S et al. Stimulating oral and nasal chemoreceptors for preventing aspiration pneumonia in the elderly. 2011 Yakugaku Zasshi pmid:22129860
Polednak AP Underestimation of menthol cigarette use among young US Black smokers: comment on the article by rock et Al. 2012 Nicotine Tob. Res. pmid:22140144
Barwood MJ et al. Early change in thermal perception is not a driver of anticipatory exercise pacing in the heat. 2012 Br J Sports Med pmid:22144003
Kawasaki H et al. Intake of dried bonito broth flavored with dextrin solution induced conditioned place preference in mice. 2011 Biosci. Biotechnol. Biochem. pmid:22146712
Rossi YE et al. Molecular response of Musca domestica L. to Mintostachys verticillata essential oil, (4R)+-pulegone and menthone. 2012 Fitoterapia pmid:22155595
Shigetomi E et al. TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. 2011 Nat. Neurosci. pmid:22158513
Vladymyrova IA et al. [Comparative effects of menthol and icilin on the induced contraction of the smooth muscles of the vas deferens of normal and castrated rats]. 2011 Fiziol Zh pmid:22164406
Brunzell DH and McIntosh JM Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia. 2012 Neuropsychopharmacology pmid:22169946
Turner GW et al. Immunocytochemical localization of short-chain family reductases involved in menthol biosynthesis in peppermint. 2012 Planta pmid:22170164
Gaudioso C et al. Menthol pain relief through cumulative inactivation of voltage-gated sodium channels. 2012 Pain pmid:22172548
Fix BV et al. Smokers' reactions to FDA regulation of tobacco products: findings from the 2009 ITC United States survey. 2011 BMC Public Health pmid:22177316
Suzuki M et al. The odor stick identification test for Japanese differentiates Parkinson's disease from multiple system atrophy and progressive supra nuclear palsy. 2011 BMC Neurol pmid:22192419
Li J et al. A cross-sectional study of menthol cigarette preference by 14- to 15-year-old smokers in New Zealand. 2012 Nicotine Tob. Res. pmid:22193580
Liu J et al. The effects of combined menthol and borneol on fluconazole permeation through the cornea ex vivo. 2012 Eur. J. Pharmacol. pmid:22200629
Wertz MS et al. The toxic effects of cigarette additives. Philip Morris' project mix reconsidered: an analysis of documents released through litigation. 2011 PLoS Med. pmid:22205885
Arikan-Ayyildiz Z et al. Anaphylaxis in an infant caused by menthol-containing cologne. 2012 May-Jun Allergol Immunopathol (Madr) pmid:22209027
Yilmaz HG and Bayindir H Clinical evaluation of chlorhexidine and essential oils for adjunctive effects in ultrasonic instrumentation of furcation involvements: a randomized controlled clinical trial. 2012 Int J Dent Hyg pmid:22212113
Park HE et al. Simple preparative gas chromatographic method for isolation of menthol and menthone from peppermint oil, with quantitative GC-MS and (1) H NMR assay. 2012 J Sep Sci pmid:22213698
Wang T et al. Phenotypic switching of nonpeptidergic cutaneous sensory neurons following peripheral nerve injury. 2011 PLoS ONE pmid:22216140
Maeda H et al. A dual catalyst system provides the shortest pathway for L-menthol synthesis. 2012 Chem. Commun. (Camb.) pmid:22218824
Prajapati MS et al. Leucas aspera: A review. 2010 Pharmacogn Rev pmid:22228946
pmid:22241835
Spanopoulos D et al. Retail price and point of sale display of tobacco in the UK: a descriptive study of small retailers. 2012 PLoS ONE pmid:22242183
Braiuca P et al. BESSICC, a COSMO-RS based tool for in silico solvent screening of biocatalyzed reactions. 2012 Biotechnol. Bioeng. pmid:22252881
Roemer E et al. Scientific assessment of the use of sugars as cigarette tobacco ingredients: a review of published and other publicly available studies. 2012 Crit. Rev. Toxicol. pmid:22263649
Okamoto Y et al. Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines. 2012 Int. J. Oncol. pmid:22267123
Gedikondele JS et al. Nose and throat complications associated with passive smoking among Congolese school children. 2011 Afr Health Sci pmid:22275918
Korać RR and Khambholja KM Potential of herbs in skin protection from ultraviolet radiation. 2011 Pharmacogn Rev pmid:22279374
Wu X et al. Mucoadhesive fenretinide patches for site-specific chemoprevention of oral cancer: enhancement of oral mucosal permeation of fenretinide by coincorporation of propylene glycol and menthol. 2012 Mol. Pharm. pmid:22280430
Hans M et al. Menthol suppresses nicotinic acetylcholine receptor functioning in sensory neurons via allosteric modulation. 2012 Chem. Senses pmid:22281529
Cox LS et al. Bupropion for smoking cessation in African American light smokers: a randomized controlled trial. 2012 J. Natl. Cancer Inst. pmid:22282543
Jeske NA Somatosensory scaffolding structures. 2012 Front Mol Neurosci pmid:22291616
Hyldgaard M et al. Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. 2012 Front Microbiol pmid:22291693
Kawashiri T et al. L type Ca²+ channel blockers prevent oxaliplatin-induced cold hyperalgesia and TRPM8 overexpression in rats. 2012 Mol Pain pmid:22292988
Taylor R et al. A randomized, double-blind comparison shows the addition of oxygenated glycerol triesters to topical mentholated cream for the treatment of acute musculoskeletal pain demonstrates incremental benefit over time. 2012 Pain Pract pmid:22304620
Abobo CV et al. Effect of menthol on nicotine pharmacokinetics in rats after cigarette smoke inhalation. 2012 Nicotine Tob. Res. pmid:22311961
Okuyemi KS et al. Effects of menthol on the pharmacokinetics of bupropion among Black smokers. 2012 Nicotine Tob. Res. pmid:22318754
Bianchi BR et al. Species comparison and pharmacological characterization of human, monkey, rat, and mouse TRPA1 channels. 2012 J. Pharmacol. Exp. Ther. pmid:22319196
Qin F et al. Quality control of modified xiaoyao san through the determination of 22 active components by ultra-performance liquid chromatography. 2011 Nov-Dec J AOAC Int pmid:22320084
Nsagha DS et al. Feasibility of home management using ACT for childhood malaria episodes in an urban setting. 2012 Drug Healthc Patient Saf pmid:22328833
pmid:22329507
Bhadania M et al. Protective effect of menthol on β-amyloid peptide induced cognitive deficits in mice. 2012 Eur. J. Pharmacol. pmid:22329901
Konidala U et al. Efficacy of various disinfectants on microbially contaminated toothbrushes due to brushing. 2011 Contemp Clin Dent pmid:22346157
Wilson AD and Baietto M Applications and advances in electronic-nose technologies. 2009 Sensors (Basel) pmid:22346690
Hunt D et al. Activating transcription factor 3 and the nervous system. 2012 Front Mol Neurosci pmid:22347845
Hiki N et al. Multicenter phase II randomized study evaluating dose-response of antiperistaltic effect of L-menthol sprayed onto the gastric mucosa for upper gastrointestinal endoscopy. 2012 Dig Endosc pmid:22348831
Jerković I et al. Volatile organic compounds from Centaurium erythraea Rafn (Croatia) and the antimicrobial potential of its essential oil. 2012 Molecules pmid:22349896
pmid:22352011
Bause GS MBC stovaine pastilles. 2012 Anesthesiology pmid:22354244
Cugati N Is flavor component in dental product therapeutic? 2012 Dent Res J (Isfahan) pmid:22363374
Pinault LL and Hunter FF Malaria Knowledge, Concern, Land Management, and Protection Practices among Land Owners and/or Managers in Lowland versus Highland Ecuador. 2011 Malar Res Treat pmid:22363897
Kahnert S et al. [Effects of menthol as an additive in tobacco products and the need for regulation]. 2012 Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz pmid:22373857
pmid:22382815
Chessa M et al. Chemical composition and antibacterial activity of the essential oil from Mentha requienii Bentham. 2013 Nat. Prod. Res. pmid:22385272
Rostron B Lung cancer mortality risk for U.S. menthol cigarette smokers. 2012 Nicotine Tob. Res. pmid:22387991
Molenaar RJ Ion channels in glioblastoma. 2011 ISRN Neurol pmid:22389824
Melis K et al. Accidental nasal eucalyptol and menthol instillation. 1990 Acta Clin Belg Suppl pmid:2239060
Camele I et al. In vitro control of post-harvest fruit rot fungi by some plant essential oil components. 2012 Int J Mol Sci pmid:22408454
Cardona V et al. Allergic diseases in the elderly. 2011 Clin Transl Allergy pmid:22409889
King B et al. The decline of menthol cigarette smoking in Australia, 1980-2008. 2012 Nicotine Tob. Res. pmid:22416116
Jiang MH et al. Comparative GC/MS analysis of essential oils extracted by 3 methods from the bud of Citrus aurantium L. var. amara Engl. 2011 Nov-Dec J. Food Sci. pmid:22416680
Paduraru OM et al. [Urothelium-dependent modulation of urinary bladder smooth muscle contractions by menthol]. 2011 Fiziol Zh pmid:22420154
Yoshihara M and Ito K Acute genetic manipulation of neuronal activity for the functional dissection of neural circuits-a dream come true for the pioneers of behavioral genetics. 2012 J. Neurogenet. pmid:22420407
Segev D et al. Chemical and morphological diversity in wild populations of Mentha longifolia in Israel. 2012 Chem. Biodivers. pmid:22422525
Sanders E et al. Does the use of ingredients added to tobacco increase cigarette addictiveness?: a detailed analysis. 2012 Inhal Toxicol pmid:22429143
Kabat GC et al. Mentholated cigarettes and smoking-related cancers revisited: an ecologic examination. 2012 Regul. Toxicol. Pharmacol. pmid:22429780
Renner B and Schreiber K Olfactory and trigeminal interaction of menthol and nicotine in humans. 2012 Exp Brain Res pmid:22434343
Avrahami D et al. A randomized, placebo-controlled double-blinded comparative clinical study of five over-the-counter non-pharmacological topical analgesics for myofascial pain: single session findings. 2012 Chiropr Man Therap pmid:22436614
Wang Y et al. Menthol inhibits the proliferation and motility of prostate cancer DU145 cells. 2012 Pathol. Oncol. Res. pmid:22437241
Mohanta TK et al. Ginkgo biloba responds to herbivory by activating early signaling and direct defenses. 2012 PLoS ONE pmid:22448229
Ceacero-Vega AA et al. Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl). 2012 J Phys Chem A pmid:22448964
Wang S et al. Warmth suppresses and desensitizes damage-sensing ion channel TRPA1. 2012 Mol Pain pmid:22458587
Klasen K et al. The TRPM8 ion channel comprises direct Gq protein-activating capacity. 2012 Pflugers Arch. pmid:22460725
Hoy NY et al. New concepts in median nail dystrophy, onychomycosis, and hand, foot, and mouth disease nail pathology. 2012 ISRN Dermatol pmid:22462009
Wise PM et al. Sweet taste and menthol increase cough reflex thresholds. 2012 Pulm Pharmacol Ther pmid:22465565
Taher YA Antinociceptive activity of Mentha piperita leaf aqueous extract in mice. 2012 Libyan J Med pmid:22468149
Mandadi S et al. Protein kinase C modulation of thermo-sensitive transient receptor potential channels: Implications for pain signaling. 2011 J Nat Sci Biol Med pmid:22470230
O'Connor RJ et al. What would menthol smokers do if menthol in cigarettes were banned? Behavioral intentions and simulated demand. 2012 Addiction pmid:22471735
Hardaker L et al. The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases. 2012 Respir. Res. pmid:22475739
Brinkman MC et al. Exposure to and deposition of fine and ultrafine particles in smokers of menthol and nonmenthol cigarettes. 2012 Inhal Toxicol pmid:22486344
Kramlinger VM et al. Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol. 2012 Chem. Biol. Interact. pmid:22486895
Muscat JE et al. Menthol smoking in relation to time to first cigarette and cotinine: results from a community-based study. 2012 Regul. Toxicol. Pharmacol. pmid:22487419
Pertusa M et al. N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons. 2012 J. Biol. Chem. pmid:22493431
Vozoris NT Mentholated cigarettes and cardiovascular and pulmonary diseases: a population-based study. 2012 Arch. Intern. Med. pmid:22493467
Patel NA et al. Comparative development and evaluation of topical gel and cream formulations of psoralen. 2009 Drug Discov Ther pmid:22495634
pmid:22497266
Umezu T Unusual effects of nicotine as a psychostimulant on ambulatory activity in mice. 2012 ISRN Pharmacol pmid:22530136
Martini C et al. Pharmacodynamic analysis of the analgesic effect of capsaicin 8% patch (Qutenzaâ„¢) in diabetic neuropathic pain patients: detection of distinct response groups. 2012 J Pain Res pmid:22536092
Kim A et al. Defects in the peripheral taste structure and function in the MRL/lpr mouse model of autoimmune disease. 2012 PLoS ONE pmid:22536412
Kataoka H and Ueno S Nightmare-enacting behavior responding to zonisamide in early Parkinson's disease. 2012 Case Rep Neurol pmid:22545035
Sherkheli MA et al. Supercooling agent icilin blocks a warmth-sensing ion channel TRPV3. 2012 ScientificWorldJournal pmid:22548000
El-Arabi AM et al. Ion channel drug potency assay with an artificial bilayer chip. 2012 Lab Chip pmid:22549308
Hummel T et al. Smell and taste disorders. 2011 GMS Curr Top Otorhinolaryngol Head Neck Surg pmid:22558054
McCoy ES et al. CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch. 2012 PLoS ONE pmid:22563493
Kono T et al. Oxaliplatin-induced neurotoxicity involves TRPM8 in the mechanism of acute hypersensitivity to cold sensation. 2012 Brain Behav pmid:22574275
Kim SH et al. Menthol induces cell-cycle arrest in PC-3 cells by down-regulating G2/M genes, including polo-like kinase 1. 2012 Biochem. Biophys. Res. Commun. pmid:22580005