(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
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Foss S and Harder J Thauera linaloolentis sp. nov. and Thauera terpenica sp. nov., isolated on oxygen-containing monoterpenes (linalool, menthol, and eucalyptol) nitrate. 1998 Syst. Appl. Microbiol. pmid:9841126
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Coffman BL et al. The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268). 1998 Drug Metab. Dispos. pmid:9443856
Tao L and Pereira MA Quantification of carvone, cineole, perillaldehyde, perillyl alcohol and sobrerol by isocratic high-performance liquid chromatography. 1998 J Chromatogr A pmid:9468652
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Gomes-Carneiro MR et al. Mutagenicity testing (+/-)-camphor, 1,8-cineole, citral, citronellal, (-)-menthol and terpineol with the Salmonella/microsome assay. 1998 Mutat. Res. pmid:9725999
Dalefield RR and Oehme FW Detection of metabolites of a veterinary counter-irritant in canine urine. 1998 Vet Hum Toxicol pmid:9682412
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Pritchard WS et al. Little evidence that "denicotinized" menthol cigarettes have pharmacological effects: an EEG/heart-rate/sujective-response study. 1999 Psychopharmacology (Berl.) pmid:10353430
Flamini G et al. Antimicrobial activity of the essential oil of Calamintha nepeta and its constituent pulegone against bacteria and fungi. 1999 Phytother Res pmid:10404547
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Kanamaru A et al. The posterior nasal nerve plays an important role on cardiopulmonary reflexes to nasal application of capsaicin, distilled water and l-menthol in anesthetized dogs. 1999 J. Vet. Med. Sci. pmid:10027173
Takanashi Y et al. Thiomenthol derivatives as novel percutaneous absorption enhancers. 1999 Drug Dev Ind Pharm pmid:10028423
Carpenter CL et al. Mentholated cigarette smoking and lung-cancer risk. 1999 Ann Epidemiol pmid:10037555
Takayama K et al. Formula optimization based on artificial neural networks in transdermal drug delivery. 1999 J Control Release pmid:10518647
Khojasteh-Bakht SC et al. Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to mintlactones. 1999 Arch. Biochem. Biophys. pmid:10496977
Zhao K and Singh J In vitro percutaneous absorption enhancement of propranolol hydrochloride through porcine epidermis by terpenes/ethanol. 1999 J Control Release pmid:10528073
Madyastha KM and Thulasiram HV Transformation of a monoterpene ketone, (R)-(+)-pulegone, a potent hepatotoxin, in Mucor piriformis. 1999 J. Agric. Food Chem. pmid:10552438
Fuchs S et al. Biogenetic studies in Mentha x piperita. 2. Stereoselectivity in the bioconversion of pulegone into menthone and isomenthone. 1999 J. Agric. Food Chem. pmid:10552608
Miyazawa M et al. Biotransformation of (+)- and (-)-menthol by the larvae of common cutworm (Spodoptera litura). 1999 J. Agric. Food Chem. pmid:10552747
Fuchs S et al. Biosynthesis of menthofuran in Mentha x piperita: stereoselective and mechanistic studies. 1999 J. Agric. Food Chem. pmid:10552773
Davidson JM et al. Effect of sucrose on the perceived flavor intensity of chewing gum. 1999 J. Agric. Food Chem. pmid:10552812
Women who smoke menthol cigarettes have greater nicotine exposure. 1999 Oncology (Williston Park, N.Y.) pmid:10442338
De-Oliveira AC et al. In vitro inhibition of liver monooxygenases by beta-ionone, 1,8-cineole, (-)-menthol and terpineol. 1999 Toxicology pmid:10454222
Gelal A et al. Disposition kinetics and effects of menthol. 1999 Clin. Pharmacol. Ther. pmid:10460066
Kitagawa S and Li H Effects of removal of stratum corneum, delipidization and addition of enhancers, ethanol and l-menthol, on skin permeation of benzoic acid and its 4-n-alkyl substituents in excised guinea pig dorsal skin. 1999 Chem. Pharm. Bull. pmid:9987825
Ahijevych K Nicotine metabolism variability and nicotine addiction. 1999 Nicotine Tob. Res. pmid:11768188
Wu X et al. [Study on the inclusion effect of menthol with beta-cyclodextrin]. 1999 Zhong Yao Cai pmid:12575080
Gall H et al. Anaphylactic shock reaction to dibutyl-phthalate-containing capsules. 1999 Dermatology (Basel) pmid:10559589
Kubota K et al. Enantiomeric purity and odor characteristics of 2- and 3-acetoxy-1, 8-cineoles in the rhizomes of Alpinia galanga willd. 1999 J. Agric. Food Chem. pmid:10563953
Barni T et al. Sex steroids and odorants modulate gonadotropin-releasing hormone secretion in primary cultures of human olfactory cells. 1999 J. Clin. Endocrinol. Metab. pmid:10566683
Shojaei AH et al. Transbuccal permeation of a nucleoside analog, dideoxycytidine: effects of menthol as a permeation enhancer. 1999 Int J Pharm pmid:10567745
Geirsson G et al. The bladder cooling reflex and the use of cooling as stimulus to the lower urinary tract. 1999 J. Urol. pmid:10569531
Ahmad VU et al. Bucharioside and buchariol from Salvia bucharica. 1999 Phytochemistry pmid:10691324
Ahijevych K and Parsley LA Smoke constituent exposure and stage of change in black and white women cigarette smokers. 1999 Jan-Feb Addict Behav pmid:10189978
Staniforth M and Khong TM Determination of encapsulated menthol flavour using thermal desorption gas chromatography. 1999 May-Jun J Microencapsul pmid:10340222
Yu D et al. Caries inhibition efficacy of an antiplaque/antigingivitis dentifrice. 2000 Am J Dent pmid:11763908