| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Uveitis, Posterior | D015866 | 5 associated lipids |
Total
3
(-)-Menthol
(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.
Cross Reference
Introduction
To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Menthol?
(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Menthol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Menthol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Menthol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (-)-Menthol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Menthol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with (-)-Menthol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Menthol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Menthol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lin YT et al. | Enantiomeric analysis of (+)-menthol and (-)-menthol by fluorogenic derivatization and liquid chromatography. | 2005 | J Chromatogr A | pmid:16130717 |
| Lin JP et al. | (-)-Menthol inhibits DNA topoisomerases I, II alpha and beta and promotes NF-kappaB expression in human gastric cancer SNU-5 cells. | 2005 May-Jun | Anticancer Res. | pmid:16158947 |
| Valverde JM et al. | Improvement of table grapes quality and safety by the combination of modified atmosphere packaging (MAP) and eugenol, menthol, or thymol. | 2005 | J. Agric. Food Chem. | pmid:16159173 |
| Thebault S et al. | Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells. | 2005 | J. Biol. Chem. | pmid:16174775 |
| GarcÃa DA et al. | Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons. | 2006 | Neuropharmacology | pmid:16185724 |
| Xu H et al. | Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. | 2005 | J. Neurosci. | pmid:16192383 |
| Green BG et al. | Chemesthesis and taste: evidence of independent processing of sensation intensity. | 2005 | Physiol. Behav. | pmid:16199067 |
| Wildung MR and Croteau RB | Genetic engineering of peppermint for improved essential oil composition and yield. | 2005 | Transgenic Res. | pmid:16201403 |
| Yong CS et al. | Enhanced oral bioavailability of ibuprofen in rats by poloxamer gel using poloxamer 188 and menthol. | 2005 | Drug Dev Ind Pharm | pmid:16207608 |
| pmid:16213622 | ||||
| Liu Y et al. | Menthol facilitates the skin analgesic effect of tetracaine gel. | 2005 | Int J Pharm | pmid:16219435 |
| Zhang YJ et al. | Permeation-enhancing effects of chitosan formulations on recombinant hirudin-2 by nasal delivery in vitro and in vivo. | 2005 | Acta Pharmacol. Sin. | pmid:16225765 |
| pmid:16229065 | ||||
| Ortiz G and Tena MT | Headspace solid-phase microextraction gas chromatography-mass spectrometry method for the identification of cosmetic ingredients causing delamination of packagings. | 2006 | J Chromatogr A | pmid:16246353 |
| Brain KR et al. | The role of menthol in skin penetration from topical formulations of ibuprofen 5% in vivo. | 2006 | Skin Pharmacol Physiol | pmid:16247245 |
| Croteau RB et al. | (-)-Menthol biosynthesis and molecular genetics. | 2005 | Naturwissenschaften | pmid:16292524 |
| Collins CC and Moolchan ET | Shorter time to first cigarette of the day in menthol adolescent cigarette smokers. | 2006 | Addict Behav | pmid:16303257 |
| pmid:16304633 | ||||
| Krishnaiah YS and Bhaskar P | Studies on the transdermal delivery of nimodipine from a menthol-based TTS in human volunteers. | 2004 | Curr Drug Deliv | pmid:16305374 |
| Finger TE et al. | ATP signaling is crucial for communication from taste buds to gustatory nerves. | 2005 | Science | pmid:16322458 |
| Premkumar LS et al. | Downregulation of transient receptor potential melastatin 8 by protein kinase C-mediated dephosphorylation. | 2005 | J. Neurosci. | pmid:16339027 |
| Thakur R and Gupta RB | Formation of phenytoin nanoparticles using rapid expansion of supercritical solution with solid cosolvent (RESS-SC) process. | 2006 | Int J Pharm | pmid:16352406 |
| pmid:16359794 | ||||
| Adamczyk S et al. | Evaluation of residues of essential oil components in honey after different anti-varroa treatments. | 2005 | J. Agric. Food Chem. | pmid:16366699 |
| Abe J et al. | Ca2+-dependent PKC activation mediates menthol-induced desensitization of transient receptor potential M8. | 2006 Apr 10-17 | Neurosci. Lett. | pmid:16380208 |
| Liu Y et al. | Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine. | 2006 | Eur. J. Pharmacol. | pmid:16386244 |
| Huang MH et al. | Stimulatory actions of thymol, a natural product, on Ca(2+)-activated K(+) current in pituitary GH(3) cells. | 2005 | Planta Med. | pmid:16395643 |
| Yang XR et al. | Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle. | 2006 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:16399784 |
| Xing H et al. | Chemical and cold sensitivity of two distinct populations of TRPM8-expressing somatosensory neurons. | 2006 | J. Neurophysiol. | pmid:16424459 |
| Lu HF et al. | The role of Ca2+ in (-)-menthol-induced human promyelocytic leukemia HL-60 cell death. | 2006 Jan-Feb | In Vivo | pmid:16433031 |
| Li Lin A et al. | Herbal monoterpene alcohols inhibit propofol metabolism and prolong anesthesia time. | 2006 | Life Sci. | pmid:16436284 |
| Liu H et al. | Effect of vehicles and enhancers on the topical delivery of cyclosporin A. | 2006 | Int J Pharm | pmid:16439077 |
| Nie Y et al. | Domino-cyclisation and hydrogenation of citronellal to menthol over bifunctional Ni/Zr-Beta and Zr-beta/Ni-MCM-41 catalysts. | 2006 | Chem. Commun. (Camb.) | pmid:16465342 |
| Obata Y et al. | The mode of promoting activity of O-ethylmenthol as a transdermal absorption enhancer. | 2006 | Pharm. Res. | pmid:16467993 |
| pmid:16476638 | ||||
| Nahm MR et al. | Metallophosphite-catalyzed asymmetric acylation of alpha,beta-unsaturated amides. | 2006 | J. Am. Chem. Soc. | pmid:16492064 |
| pmid:16492529 | ||||
| Kakubari I et al. | Formulation and evaluation of ethylene-vinyl acetate copolymer matrix patches containing formoterol fumarate. | 2006 | Biol. Pharm. Bull. | pmid:16508156 |
| Mukerji G et al. | Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations. | 2006 | BMC Urol | pmid:16519806 |
| Bandell M et al. | High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol. | 2006 | Nat. Neurosci. | pmid:16520735 |
| Hatem S et al. | Psychophysical study of the effects of topical application of menthol in healthy volunteers. | 2006 | Pain | pmid:16527405 |
| pmid:16536610 | ||||
| Ly KA et al. | Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial [ISRCTN43479664]. | 2006 | BMC Oral Health | pmid:16556326 |
| pmid:16563603 | ||||
| Montell C | A mint of mutations in TRPM8 leads to cool results. | 2006 | Nat. Neurosci. | pmid:16568102 |
| Park CK et al. | Functional expression of thermo-transient receptor potential channels in dental primary afferent neurons: implication for tooth pain. | 2006 | J. Biol. Chem. | pmid:16595689 |
| Abu Hena Mostofa Kamal M et al. | Enhanced skin permeation of salicylate by ion-pair formation in non-aqueous vehicle and further enhancement by ethanol and l-menthol. | 2006 | Chem. Pharm. Bull. | pmid:16595949 |
| Dolder S et al. | Effect of monoterpenes on the formation and activation of osteoclasts in vitro. | 2006 | J. Bone Miner. Res. | pmid:16598385 |
| Zhang L and Barritt GJ | TRPM8 in prostate cancer cells: a potential diagnostic and prognostic marker with a secretory function? | 2006 | Endocr. Relat. Cancer | pmid:16601277 |
| Trongtokit Y et al. | Efficacy of repellent products against caged and free flying Anopheles stephensi mosquitoes. | 2005 | Southeast Asian J. Trop. Med. Public Health | pmid:16610644 |