(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

Cross Reference

Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

Download all related citations
Per page 10 20 50 100 | Total 2230
Authors Title Published Journal PubMed Link
Carpenter CL et al. Mentholated cigarette smoking and lung-cancer risk. 1999 Ann Epidemiol pmid:10037555
Sleth JC [The Bonain anesthetic mixture: a forgotten ancestor of Emla cream?]. 1998 Ann Fr Anesth Reanim pmid:9750756
PICCOLI A [THE L-MENTHYL ESTER OF D-PANTOTHENIC ACID IN THE TREATMENT OF SOME RHINOPATHIES]. 1963 Sep-Oct Ann Laringol Otol Rinol Faringol pmid:14091285
Jankowski R et al. [Advantages of the L-menthol test in assessing chronic nasal obstruction]. 2008 Ann Otolaryngol Chir Cervicofac pmid:18774552
DOMANGE L [Efficacious process of dehydration before sublimation in quantitative analysis; application to menthol determination]. 1950 Ann Pharm Fr pmid:14811206
[Not Available]. 1954 Ann Pharm Fr pmid:14362140
LEMLI JA [Determination of menthone, menthol and menthofuran in essential oil of Mentha; localization of menthofuran in the plant]. 1954 Ann Pharm Fr pmid:13189199
HAZARD R and LECHAT P [Comparative toxicity of natural menthol and racemic synthetic menthol]. 1952 Jul-Aug Ann Pharm Fr pmid:13008218
Hérisset A and Besson P [Attempt of "industrial lyophilization" of medicinal plants. V. Peppermint (Mentha piperita Huds. L.)]. 1967 Ann Pharm Fr pmid:5611541
Montes M et al. [Determination of pulegone in the essential oil of Mentha pulegium L. from Chile]. 1986 Ann Pharm Fr pmid:3777785
Kassebaum PJ et al. Possible warfarin interaction with menthol cough drops. 2005 Ann Pharmacother pmid:15644472
Familusi JB and Dawodu AH A survey of neonatal jaundice in association with household drugs and chemicals in Nigeria. 1985 Ann Trop Paediatr pmid:2418773
Al-Bayati FA Isolation and identification of antimicrobial compound from Mentha longifolia L. leaves grown wild in Iraq. 2009 Ann. Clin. Microbiol. Antimicrob. pmid:19523224
Anderson IB et al. Pennyroyal toxicity: measurement of toxic metabolite levels in two cases and review of the literature. 1996 Ann. Intern. Med. pmid:8633832
Carbone E and Lux HD Modulation of Ca channels in peripheral neurons. 1989 Ann. N. Y. Acad. Sci. pmid:2545142
Gerhold KA and Bautista DM Molecular and cellular mechanisms of trigeminal chemosensation. 2009 Ann. N. Y. Acad. Sci. pmid:19686135
Kivity S et al. Abnormal olfactory function demonstrated by manganese-enhanced MRI in mice with experimental neuropsychiatric lupus. 2010 Ann. N. Y. Acad. Sci. pmid:20398010
Lin JP et al. (-)-Menthol inhibits DNA topoisomerases I, II alpha and beta and promotes NF-kappaB expression in human gastric cancer SNU-5 cells. 2005 May-Jun Anticancer Res. pmid:16158947
Trombetta D et al. Mechanisms of antibacterial action of three monoterpenes. 2005 Antimicrob. Agents Chemother. pmid:15917549
Eccles R Role of cold receptors and menthol in thirst, the drive to breathe and arousal. 2000 Appetite pmid:10744889
Zhang Y et al. Effects of caffeine and menthol on cognition and mood during simulated firefighting in the heat. 2014 Appl Ergon pmid:23891504
TAYLOR R CHEMICAL STIMULANTS TO RESPIRATION. 1963 Appl Ther pmid:14084568
Ngo-Thi MT et al. Enantioselective hydrolysis of dl-menthyl benzoate by cell-free extract of newly isolated Acinetobacter sp. ECU2040. 2013 Appl. Biochem. Biotechnol. pmid:23801098
Landau E and Shapira R Effects of subinhibitory concentrations of menthol on adaptation, morphological, and gene expression changes in enterohemorrhagic Escherichia coli. 2012 Appl. Environ. Microbiol. pmid:22635999
Matsuoka H et al. Evaluation of antifungal volatile compounds on the basis of the elongation rate of a single hypha. 1990 Appl. Environ. Microbiol. pmid:2082824
Qiu J et al. Menthol diminishes Staphylococcus aureus virulence-associated extracellular proteins expression. 2011 Appl. Microbiol. Biotechnol. pmid:21287163
MAKHKAMOV SM [On the problem of the preparation and research on validol tablets]. 1962 Jan-Feb Aptechn Delo pmid:14468699
Bitman SI and ChausovskiÄ­ SS [Photocolorimetric determination of menthol]. 1966 May-Jun Aptechn Delo pmid:5993404
McGowan EM Menthol urticaria. 1966 Arch Dermatol pmid:5938225
Chrisman BB Menthol and dermatitis. 1978 Arch Dermatol pmid:629559
Teller H [Drug therapy in rectal diseases]. 1972 Arch Dermatol Forsch pmid:4405403
Boyd EM and Sheppard EP A bronchomucotropic action in rabbits from inhaled menthol and thymol. 1969 Arch Int Pharmacodyn Ther pmid:5365236
Hansen D [A simple method for a quantitative smelling test in clinical medicine and general practice]. 1965 Arch Ohren Nasen Kehlkopfheilkd pmid:5881116
ZILSTORFF K SENSE OF SMELL ALTERATIONS BY COCAINE AND TETRACAINE. 1965 Arch Otolaryngol pmid:14310180
Strutz J et al. Effects of topical anesthetics on tympanic membrane structure. 1988 Arch Otorhinolaryngol pmid:3348754
NEUDERT W and HUBER J [Double freezing point and a gas chromatographic method for the qualitative investigation of DL-menthols]. 1962 Arch Pharm pmid:14479160
HUECKEL W and JORDAN E [The isomerization of menthol and the 3 enol acetats of 3-menthanone]. 1961 Arch Pharm pmid:13716537
BOEHME H et al. [On the menthol monography in a new German pharmocopoeia. Part I]. 1960 Arch Pharm pmid:13801996
VON BOHME H and VAN EMSTER K [On the assay of DL-menthol for contamination by DL-neomenthol. 2. Report on the menthol monography in a new German pharmacopoeia]. 1960 Arch Pharm pmid:13801997
Khojasteh-Bakht SC et al. Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to mintlactones. 1999 Arch. Biochem. Biophys. pmid:10496977
Croteau R et al. Biosynthesis of monoterpenes: partial purification, characterization, and mechanism of action of 1,8-cineole synthase. 1994 Arch. Biochem. Biophys. pmid:8117108
Bertea CM et al. Demonstration that menthofuran synthase of mint (Mentha) is a cytochrome P450 monooxygenase: cloning, functional expression, and characterization of the responsible gene. 2001 Arch. Biochem. Biophys. pmid:11396930
Ringer KL et al. Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint. 2003 Arch. Biochem. Biophys. pmid:13679086
Croteau R and Venkatachalam KV Metabolism of monoterpenes: demonstration that (+)-cis-isopulegone, not piperitenone, is the key intermediate in the conversion of (-)-isopiperitenone to (+)-pulegone in peppermint (Mentha piperita). 1986 Arch. Biochem. Biophys. pmid:3755881
Kjonaas R and Croteau R Demonstration that limonene is the first cyclic intermediate in the biosynthesis of oxygenated p-menthane monoterpenes in Mentha piperita and other Mentha species. 1983 Arch. Biochem. Biophys. pmid:6830247
Wallengren J Tea tree oil attenuates experimental contact dermatitis. 2011 Arch. Dermatol. Res. pmid:20865268
Yosipovitch G et al. Effect of topically applied menthol on thermal, pain and itch sensations and biophysical properties of the skin. 1996 Arch. Dermatol. Res. pmid:8738567
Vozoris NT Mentholated cigarettes and cardiovascular and pulmonary diseases: a population-based study. 2012 Arch. Intern. Med. pmid:22493467
Sidney S et al. Mentholated cigarette use and lung cancer. 1995 Arch. Intern. Med. pmid:7695461
Pletcher MJ et al. Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. 2006 Arch. Intern. Med. pmid:17000950