| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Uveitis, Posterior | D015866 | 5 associated lipids |
Total
3
(-)-Menthol
(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.
Cross Reference
Introduction
To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Menthol?
(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Menthol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Menthol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Menthol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (-)-Menthol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Menthol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (-)-Menthol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Menthol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Menthol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Blanchard DL | Sting Eze keratitis. | 1989 | Arch. Ophthalmol. | pmid:2730388 |
| Simon SA and Sostman AL | Electrophysiological responses to non-electrolytes in lingual nerve of rat and in lingual epithelia of dog. | 1991 | Arch. Oral Biol. | pmid:1722391 |
| Kalantzis A et al. | Effects of capsaicin and menthol on oral thermal sensory thresholds. | 2007 | Arch. Oral Biol. | pmid:17045956 |
| Brieskorn CH and Schlicht W | [The constitution of a crystalline complex of iron(iii)- thiocyanate with cineol (author's transl)]. | 1977 | Arch. Pharm. (Weinheim) | pmid:860899 |
| Kuhnert-Brandstätter M and Ulmer R | [Thermal analytical and i.r.spectroscopic investigations on menthols (author's transl)]. | 1974 | Arch. Pharm. (Weinheim) | pmid:4849988 |
| Kuhnert-Brandstätter M et al. | [Thermal analytical investigations on menthols (author's transl)]. | 1974 | Arch. Pharm. (Weinheim) | pmid:4849989 |
| Auterhoff H and Bertram H | [Colour reactions via cyclopentenyl cations (author's transl)]. | 1974 | Arch. Pharm. (Weinheim) | pmid:4423261 |
| Mishra V et al. | Anti-HIV activity of thiosemicarbazone and semicarbazone derivatives of (+/-)-3-menthone. | 2002 | Arch. Pharm. (Weinheim) | pmid:12210774 |
| Sharma S et al. | Optimization of promethazine theoclate fast dissolving tablet using pore forming technology by 3-factor, 3-level response surface-full factorial design. | 2010 | Arch. Pharm. Res. | pmid:20803123 |
| Okyar A et al. | The effect of terpenes on percutaneous absorption of tiaprofenic acid gel. | 2010 | Arch. Pharm. Res. | pmid:21116781 |
| Shehata M et al. | Induction of DNA double-strand breaks by monochlorophenol isomers and ChKM in human gingival fibroblasts. | 2012 | Arch. Toxicol. | pmid:22614568 |
| COHEN SL and SCHOENE FC | Lipoid pneumonia. A case report. | 1963 | Ariz Med | pmid:14022102 |
| McDougall JJ | Arthritis and pain. Neurogenic origin of joint pain. | 2006 | Arthritis Res. Ther. | pmid:17118212 |
| Schaible HG et al. | Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines. | 2011 | Arthritis Res. Ther. | pmid:21542894 |
| Szabon J et al. | [Effect of drug solutions on the activity of the ciliary epithelium of the nasal mucosa]. | 1970 | Arzneimittelforschung | pmid:5536508 |
| Mascher H et al. | Pharmacokinetics of menthol and carvone after administration of an enteric coated formulation containing peppermint oil and caraway oil. | 2001 | Arzneimittelforschung | pmid:11455677 |
| Wu JF et al. | Bioequivalence evaluation of menthol after oral administration of peppermint oil soft capsules in dogs. | 2010 | Arzneimittelforschung | pmid:20863003 |
| Schäfer D and Schäfer W | [Pharmacological studies with an ointment containing menthol, camphene and essential oils for broncholytic and secretolytic effects]. | 1981 | Arzneimittelforschung | pmid:7194098 |
| Schäfer R and Schäfer W | [Percutaneous absorption of various terpenes - menthol, camphene, limonene, isoborneol-acetate, alpha-pinene - from foam baths (author's transl)]. | 1982 | Arzneimittelforschung | pmid:7199340 |
| Riechelmann H et al. | Response of human ciliated respiratory cells to a mixture of menthol, eucalyptus oil and pine needle oil. | 1997 | Arzneimittelforschung | pmid:9342418 |
| Almirall M et al. | Effect of d-limonene, alpha-pinene and cineole on in vitro transdermal human skin penetration of chlorpromazine and haloperidol. | 1996 | Arzneimittelforschung | pmid:8842336 |
| Abd-ElGawad AE et al. | Comparison of different perrmeation enhancers on topical ketoconazole formulations. | 2007 | Arzneimittelforschung | pmid:17341008 |
| Chow SK | Management of chronic urticaria in Asia: 2010 AADV consensus guidelines. | 2012 | Asia Pac Allergy | pmid:22701866 |
| Ali MS et al. | In vitro antioxidant, cytotoxic, thrombolytic activities and phytochemical evaluation of methanol extract of the A. philippense L. leaves. | 2013 | Asian Pac J Trop Biomed | pmid:23730559 |
| Kijpornyongpan T et al. | Dose-dependent cytotoxic effects of menthol on human malignant melanoma A-375 cells: correlation with TRPM8 transcript expression. | 2014 | Asian Pac. J. Cancer Prev. | pmid:24641366 |
| Palop Larrea V et al. | [Pastillas Juanola and arterial hypertension]. | 1997 | Aten Primaria | pmid:9453779 |
| Ishimaru T et al. | Zinc modulates the electro-olfactogram of the frog. | 2000 | Auris Nasus Larynx | pmid:10808115 |
| Naito K et al. | The effect of L-menthol stimulation of the major palatine nerve on nasal patency. | 1991 | Auris Nasus Larynx | pmid:1799329 |
| Naito K et al. | The effect of L-menthol stimulation of the major palatine nerve on subjective and objective nasal patency. | 1997 | Auris Nasus Larynx | pmid:9134138 |
| Narracott P | An in vitro comparison of the single cone and lateral condensation techniques using 'friction-fitted' and 'solvent dip-fitted' primary gutta-percha cones. | 1989 | Aust Dent J | pmid:2705940 |
| Kelly BR | Respiratory preparations. | 1993 | Aust Fam Physician | pmid:8379888 |
| Holley WC | Cold sores and shingles. | 1995 | Aust Fam Physician | pmid:7625954 |
| Schattner P and Randerson D | Tiger Balm as a treatment of tension headache. A clinical trial in general practice. | 1996 | Aust Fam Physician | pmid:8839380 |
| Wilson N et al. | Smokers have varying misperceptions about the harmfulness of menthol cigarettes: national survey data. | 2011 | Aust N Z J Public Health | pmid:21806732 |
| Marsh L et al. | A refreshing poison: one-quarter of young New Zealand smokers choose menthol. | 2012 | Aust N Z J Public Health | pmid:23025381 |
| Kashima H and Hayashi N | Facial skin blood flow responses to irritant stimuli in the oral cavity. | 2013 | Auton Neurosci | pmid:23265982 |
| Tanabe A et al. | Effects of corticotropin-releasing factor on intermediolateral cell column neurons of newborn rats. | 2012 | Auton Neurosci | pmid:23151516 |
| Klein AH et al. | Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats. | 2010 | Behav. Brain Res. | pmid:20398704 |
| Green BG and Schoen KL | Thermal and nociceptive sensations from menthol and their suppression by dynamic contact. | 2007 | Behav. Brain Res. | pmid:17092576 |
| Wondergem R et al. | HGF/SF and menthol increase human glioblastoma cell calcium and migration. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18485891 |
| Vadiraja BB et al. | Hepatoprotective effect of C-phycocyanin: protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicty in rats. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9712713 |
| Kim SH et al. | Menthol induces cell-cycle arrest in PC-3 cells by down-regulating G2/M genes, including polo-like kinase 1. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22580005 |
| Madyastha KM and Raj CP | Biotransformations of R-(+)-pulegone and menthofuran in vitro: chemical basis for toxicity. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2268314 |
| Kim KY et al. | TRP-independent inhibition of the phospholipase C pathway by natural sensory ligands. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18371303 |
| Takeuchi S et al. | Effect of menthol on cytosolic Ca2+ levels in canine airway epithelium in culture. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8024577 |
| Hui K et al. | Biophysical properties of menthol-activated cold receptor TRPM8 channels. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15950184 |
| Madyastha P et al. | In vivo and in vitro destruction of rat liver cytochrome P-450 by a monoterpene ketone, pulegone. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3994727 |
| Samad A et al. | The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1. | 2011 | Biochem. J. | pmid:20946100 |
| Lavender V et al. | Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion. | 2008 | Biochem. J. | pmid:18452405 |
| STOREY ID | SOME DIFFERENCES IN THE CONJUGATION OF O-AMINOPHENOL AND P-NITROPHENOL BY THE URIDINE DIPHOSPHATE TRANSGLUCURONYLASE OF MOUSE-LIVER HOMOGENATES. | 1965 | Biochem. J. | pmid:14333559 |