(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

Cross Reference

Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
pmid:25719613
pmid:25698775
Sharara AI et al. Split-dose menthol-enhanced PEG vs PEG-ascorbic acid for colonoscopy preparation. 2015 World J. Gastroenterol. pmid:25684963
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Fallon MT et al. Cancer treatment-related neuropathic pain: proof of concept study with menthol--a TRPM8 agonist. 2015 Support Care Cancer pmid:25680765
Ha MA et al. Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice. 2015 PLoS ONE pmid:25679525
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Lehto SG et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. 2015 Naunyn Schmiedebergs Arch. Pharmacol. pmid:25662185
Wackowski OA et al. Switching to E-Cigarettes in the Event of a Menthol Cigarette Ban. 2015 Nicotine Tob. Res. pmid:25634935
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Choonara BF et al. A menthol-based solid dispersion technique for enhanced solubility and dissolution of sulfamethoxazole from an oral tablet matrix. 2015 AAPS PharmSciTech pmid:25549792
Liu BY et al. Menthol suppresses laryngeal C-fiber hypersensitivity to cigarette smoke in a rat model of gastroesophageal reflux disease: the role of TRPM8. 2015 J. Appl. Physiol. pmid:25539933
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Rath JM et al. Patterns of Longitudinal Transitions in Menthol Use Among US Young Adult Smokers. 2015 Nicotine Tob. Res. pmid:25480932
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Moorthy B et al. Hepatotoxicity of pulegone in rats: its effects on microsomal enzymes, in vivo. 1989 Toxicology pmid:2541521
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Ramos-Filho AC et al. Menthol inhibits detrusor contractility independently of TRPM8 activation. 2014 PLoS ONE pmid:25375115
Pezzoli M et al. Dampened neural activity and abolition of epileptic-like activity in cortical slices by active ingredients of spices. 2014 Sci Rep pmid:25359561
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Romero MC et al. Peppermint (Mentha piperita) and albendazole against anisakiasis in an animal model. 2014 Trop. Med. Int. Health pmid:25330410
Park SJ et al. Menthol cigarette smoking in the COPDGene cohort: relationship with COPD, comorbidities and CT metrics. 2015 Respirology pmid:25328036
pmid:25285505
Zuo Y et al. Sex-specific effects of cigarette mentholation on brain nicotine accumulation and smoking behavior. 2015 Neuropsychopharmacology pmid:25267342
Ali A et al. New withanolide, acyl and menthyl glucosides from fruits of Withania coagulans Dunal. 2014 May-Jun Acta Pol Pharm pmid:25265822
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Fallin A et al. Menthol cigarette smoking among lesbian, gay, bisexual, and transgender adults. 2015 Am J Prev Med pmid:25245795
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Willershausen I et al. Influence of E-smoking liquids on human periodontal ligament fibroblasts. 2014 Head Face Med pmid:25224853
Thihalolipavan S et al. Menthol smokers in large-scale nicotine replacement therapy program. 2014 Am J Public Health pmid:25211736
McClanahan RH et al. Metabolic activation of (R)-(+)-pulegone to a reactive enonal that covalently binds to mouse liver proteins. 1989 Sep-Oct Chem. Res. Toxicol. pmid:2519826
Young-Wolff KC et al. Correlates and prevalence of menthol cigarette use among adults with serious mental illness. 2015 Nicotine Tob. Res. pmid:25190706
pmid:25178275