| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Uveitis, Posterior | D015866 | 5 associated lipids |
Total
3
(-)-Menthol
(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.
Cross Reference
Introduction
To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Menthol?
(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Menthol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Menthol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Menthol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (-)-Menthol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Menthol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (-)-Menthol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Menthol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Menthol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lavender V et al. | Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion. | 2008 | Biochem. J. | pmid:18452405 |
| Hohenwallner W and Klima J | In vivo activation of glucuronyl transferase in rat liver by eucalyptole. | 1971 | Biochem. Pharmacol. | pmid:5132892 |
| Jori A et al. | Effect of essential oils on drug metabolism. | 1969 | Biochem. Pharmacol. | pmid:5345885 |
| Austin CA et al. | The effect of terpenoid compounds on cytochrome P-450 levels in rat liver. | 1988 | Biochem. Pharmacol. | pmid:3377821 |
| Liu K et al. | NPPB structure-specifically activates TRPA1 channels. | 2010 | Biochem. Pharmacol. | pmid:20226176 |
| Rath P et al. | Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain. | 2016 | Biochemistry | pmid:26653082 |
| Bouchard M et al. | Membrane fluidity response to odorants as seen by 2H-NMR and infrared spectroscopy. | 1996 | Biochim. Biophys. Acta | pmid:8703978 |
| Persaud KC et al. | Ion transport across the frog olfactory mucosa: the basal and odorant-stimulated states. | 1987 | Biochim. Biophys. Acta | pmid:2440480 |
| Cortright DN et al. | TRP channels and pain. | 2007 | Biochim. Biophys. Acta | pmid:17467247 |
| Turina AV et al. | Monoterpenes affect chlorodiazepoxide-micelle interaction through micellar dipole potential modifications. | 2003 | Biochim. Biophys. Acta | pmid:14561468 |
| Pedretti A et al. | Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features. | 2009 | Biochim. Biophys. Acta | pmid:19230823 |
| Chen H et al. | A combination of site-directed mutagenesis and chemical modification to improve diastereopreference of Pseudomonas alcaligenes lipase. | 2013 | Biochim. Biophys. Acta | pmid:24012560 |
| Kim SH et al. | Menthol regulates TRPM8-independent processes in PC-3 prostate cancer cells. | 2009 | Biochim. Biophys. Acta | pmid:18955132 |
| Trudgill PW | Microbial metabolism of monoterpenes--recent developments. | 1990 | Biodegradation | pmid:1368150 |
| da Silveira NS et al. | The aversive, anxiolytic-like, and verapamil-sensitive psychostimulant effects of pulegone. | 2014 | Biol. Pharm. Bull. | pmid:24790000 |
| Hendradi E et al. | Effect of mixed micelle formulations including terpenes on the transdermal delivery of diclofenac. | 2003 | Biol. Pharm. Bull. | pmid:14646182 |
| Li CJ et al. | Promoting mechanism of menthol derivative, 1-O-ethyl-3-buthylcyclohexanol, on the percutaneous absorption of ketoprofen. | 2001 | Biol. Pharm. Bull. | pmid:11558566 |
| Morimoto Y et al. | In vitro skin permeation of morphine hydrochloride during the finite application of penetration-enhancing system containing water, ethanol and l-menthol. | 2002 | Biol. Pharm. Bull. | pmid:11824544 |
| Kigasawa K et al. | In vivo transdermal delivery of diclofenac by ion-exchange iontophoresis with geraniol. | 2009 | Biol. Pharm. Bull. | pmid:19336905 |
| Duangjit S et al. | Menthosomes, novel ultradeformable vesicles for transdermal drug delivery: optimization and characterization. | 2012 | Biol. Pharm. Bull. | pmid:23037161 |
| Hoshino M et al. | Effects of menthol on the pharmacokinetics of triazolam and phenytoin. | 2015 | Biol. Pharm. Bull. | pmid:25757928 |
| Kakubari I et al. | Formulation and evaluation of ethylene-vinyl acetate copolymer matrix patches containing formoterol fumarate. | 2006 | Biol. Pharm. Bull. | pmid:16508156 |
| Matsui R et al. | Combination effect of physical and gustatory taste masking for propiverine hydrochloride orally disintegrating tablets on palatability. | 2015 | Biol. Pharm. Bull. | pmid:25744453 |
| Morimoto Y et al. | Effect of l-menthol-ethanol-water system on the systemic absorption of flurbiprofen after repeated topical applications in rabbits. | 2000 | Biol. Pharm. Bull. | pmid:11041263 |
| Kobayashi D et al. | Feasibility of use of several cardiovascular agents in transdermal therapeutic systems with l-menthol-ethanol system on hairless rat and human skin. | 1993 | Biol. Pharm. Bull. | pmid:8364469 |
| Obata Y et al. | Effect of pretreatment of skin with cyclic monoterpenes on permeation of diclofenac in hairless rat. | 1993 | Biol. Pharm. Bull. | pmid:8364480 |
| Ditrichova D et al. | Oral lichenoid lesions and allergy to dental materials. | 2007 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | pmid:18345274 |
| Lin R et al. | Analysis of menthol in three traditional Chinese medicinal herbs and their compound formulation by GC-MS. | 2002 | Biomed. Chromatogr. | pmid:11920950 |
| SantamarÃa E et al. | [Field efficacy of repellent formulation containing para-menthane-3,8-diol and lemongrass against Culicoides pachymerus (Diptera: Ceratopogonidae) in Colombia]. | 2012 | Biomedica | pmid:23715194 |
| Ortar G et al. | (-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20378345 |
| DeFalco J et al. | 5-benzyloxytryptamine as an antagonist of TRPM8. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20965726 |
| Li S et al. | Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cells. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24210499 |
| Narishetty ST and Panchagnula R | Transdermal delivery system for zidovudine: in vitro, ex vivo and in vivo evaluation. | 2004 | Biopharm Drug Dispos | pmid:14716748 |
| Jain AK and Panchagnula R | Transdermal delivery of imipramine hydrochloride: development and evaluation (in vitro and in vivo) of reservoir gel formulation. | 2005 | Biopharm Drug Dispos | pmid:15614831 |
| Cal K | Skin disposition of menthol after its application in the presence of drug substances. | 2008 | Biopharm Drug Dispos | pmid:18985797 |
| Nagatomo K et al. | The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppression. | 2010 | Biophys. J. | pmid:21112285 |
| Yamamoto H and Hayakawa T | Syntheses of poly[beta-(l)-menthyl D- and L-aspartates] and their secondary structures. | 1971 | Biopolymers | pmid:5545525 |
| Gupta ML et al. | Effect of the vesicular-arbuscular mycorrhizal (VAM) fungus Glomus fasciculatum on the essential oil yield related characters and nutrient acquisition in the crops of different cultivars of menthol mint (Mentha arvensis) under field conditions. | 2002 | Bioresour. Technol. | pmid:11708758 |
| Ram D et al. | Optimization of water and nitrogen application to menthol mint (Mentha arvensis L.) through sugarcane trash mulch in a sandy loam soil of semi-arid subtropical climate. | 2006 | Bioresour. Technol. | pmid:16005209 |
| Li Z et al. | Dual response surface-optimized synthesis of L-menthyl conjugated linoleate in solvent-free system by Candida rugosa lipase. | 2010 | Bioresour. Technol. | pmid:19833506 |
| Miyazawa M and Nakanishi K | Biotransformation of (-)-menthone by human liver microsomes. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16717432 |
| Shimizu K et al. | Essential oil of lavender inhibited the decreased attention during a long-term task in humans. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18603803 |
| Nakagawa H et al. | Anomer-selective glucosylation of l-menthol by yeast alpha-glucosidase. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9720215 |
| Masamoto Y et al. | Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19420725 |
| Sassa T et al. | (+)-Menthol and its hydroxy derivatives, novel fungal monoterpenols from the fusicoccin-producing fungi, Phomopsis amygdali F6a and Niigata 2. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12723593 |
| Nagamatsu R et al. | Cleavage of α-dicarbonyl compounds by terpene hydroperoxide. | 2012 | Biosci. Biotechnol. Biochem. | pmid:23047102 |
| Kawasaki H et al. | Intake of dried bonito broth flavored with dextrin solution induced conditioned place preference in mice. | 2011 | Biosci. Biotechnol. Biochem. | pmid:22146712 |
| Liu XD et al. | Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying. | 2000 | Biosci. Biotechnol. Biochem. | pmid:10993145 |
| Szymańska I et al. | Fullerene modified supported lipid membrane as sensitive element of sensor for odorants. | 2001 | Biosens Bioelectron | pmid:11679270 |
| Braiuca P et al. | BESSICC, a COSMO-RS based tool for in silico solvent screening of biocatalyzed reactions. | 2012 | Biotechnol. Bioeng. | pmid:22252881 |