(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

Cross Reference

Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

Download all related citations
Per page 10 20 50 100 | Total 2230
Authors Title Published Journal PubMed Link
Patel DM and Patel MM Optimization of fast dissolving etoricoxib tablets prepared by sublimation technique. 2008 Indian J Pharm Sci pmid:20390084
Bhatia SP et al. Fragrance material review on d-menthol. 2008 Food Chem. Toxicol. pmid:18640220
Bhatia SP et al. Fragrance material review on 4-carvomenthenol. 2008 Food Chem. Toxicol. pmid:18640221
Bhatia SP et al. Fragrance material review on l-menthol. 2008 Food Chem. Toxicol. pmid:18640225
Jankowski R et al. [Advantages of the L-menthol test in assessing chronic nasal obstruction]. 2008 Ann Otolaryngol Chir Cervicofac pmid:18774552
Neubert JK et al. Characterization of mouse orofacial pain and the effects of lesioning TRPV1-expressing neurons on operant behavior. 2008 Mol Pain pmid:18828909
Johnson DM et al. Designing a tobacco counter-marketing campaign for African American youth. 2008 Tob Induc Dis pmid:18822164
Mwenifumbo JC et al. Socioeconomic and drug use determinants of smoking status in an urban adult population of Black African descent. 2008 Nicotine Tob. Res. pmid:18686179
Macfarlane JT and Worboys M The changing management of acute bronchitis in Britain, 1940-1970: the impact of antibiotics. 2008 Med Hist pmid:18180811
Wong RW and Rabie AB Local massage with topical analgesic, a novel treatment modality for temporomandibular muscular pain, a case study report of 5 consecutive cases. 2008 Open Orthop J pmid:19506702
Zhao L et al. Transdermal delivery of penetrants with differing lipophilicities using O-acylmenthol derivatives as penetration enhancers. 2008 Eur J Pharm Biopharm pmid:18065216
Dambolena JS et al. Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. 2008 Toxicon pmid:18037463
Samarasekera R et al. Insecticidal activity of menthol derivatives against mosquitoes. 2008 Pest Manag. Sci. pmid:18095385
Haas AL et al. Cigarette smoking in opioid-using patients presenting for hospital-based medical services. 2008 Jan-Feb Am J Addict pmid:18214725
Lindemann J et al. Impact of menthol inhalation on nasal mucosal temperature and nasal patency. 2008 Jul-Aug Am J Rhinol pmid:18702906
Shirwaikar A et al. Herbal excipients in novel drug delivery systems. 2008 Jul-Aug Indian J Pharm Sci pmid:20046764
Gannu R et al. In vitro permeation of carvedilol through porcine skin: effect of vehicles and penetration enhancers. 2008 Jul-Aug PDA J Pharm Sci Technol pmid:19174954
Kozyreva TV and Tkachenko EIa [Effect of menthol on human temperature sensitivity]. 2008 Mar-Apr Fiziol Cheloveka pmid:18472579
Patel D et al. Design, development, and optimization of orally disintegrating tablets of etoricoxib using vacuum-drying approach. 2008 May-Jun PDA J Pharm Sci Technol pmid:18661871
Song JP et al. [Study on the dynamic change of essential components in Folium Apocyni Veneti]. 2009 Zhong Yao Cai pmid:20218285
Guide to Receptors and Channels (GRAC), 4th Edition. 2009 Br. J. Pharmacol. pmid:19883461
Malkia A et al. Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels. 2009 Mol Pain pmid:19886999
Campero M et al. Human cutaneous C fibres activated by cooling, heating and menthol. 2009 J. Physiol. (Lond.) pmid:19822550
Prasad R et al. Studies on in vitro and in vivo transdermal flux enhancement of methotrexate by a combinational approach in comparison to oral delivery. 2009 Drug Dev Ind Pharm pmid:19832628
Gundersen DA et al. Exploring the relationship between race/ethnicity, menthol smoking, and cessation, in a nationally representative sample of adults. 2009 Prev Med pmid:19850064
Mitka M FDA exercises new authority to regulate tobacco products, but some limits remain. 2009 JAMA pmid:19920227
Cahusac PM Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle. 2009 J. Peripher. Nerv. Syst. pmid:20021572
Chandola HC and Chakraborty A Fibromyalgia and myofascial pain syndrome-a dilemma. 2009 Indian J Anaesth pmid:20640108
Ajala T et al. There may be a link between intrahepatic cholestasis of pregnancy and familial combined hyperlipidaemia: a case report. 2009 Cases J pmid:20181214
Yadav S and Bajaj AK Management of difficult urticaria. 2009 Indian J Dermatol pmid:20161863
Goh CL and Tan KT Chronic autoimmune urticaria: where we stand? 2009 Indian J Dermatol pmid:20161862
Godse KV Chronic urticaria and treatment options. 2009 Indian J Dermatol pmid:20101328
Signorello LB et al. Racial differences in serum cotinine levels of smokers. 2009 Dis. Markers pmid:20037205
Miyamoto T et al. TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice. 2009 PLoS ONE pmid:19893614
Patel NA et al. Comparative development and evaluation of topical gel and cream formulations of psoralen. 2009 Drug Discov Ther pmid:22495634
Hodge JJ Ion channels to inactivate neurons in Drosophila. 2009 Front Mol Neurosci pmid:19750193
Kochukov MY et al. Tumor necrosis factor-alpha (TNF-alpha) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes. 2009 Mol Pain pmid:19695100
Park CW et al. Development of guideline for rating the physical impairment of otolaryngologic field. 2009 J. Korean Med. Sci. pmid:19503682
Myers BR et al. Evolution of thermal response properties in a cold-activated TRP channel. 2009 PLoS ONE pmid:19492038
Sherkheli MA et al. Monoterpenoids induce agonist-specific desensitization of transient receptor potential vanilloid-3 (TRPV3) ion channels. 2009 J Pharm Pharm Sci pmid:19470296
Gohel MC and Nagori SA Fabrication of modified transport fluconazole transdermal spray containing ethyl cellulose and Eudragit RS100 as film formers. 2009 AAPS PharmSciTech pmid:19462250
Mayo JA and Ritchie JR Acidogenic potential of "sugar-free" cough drops. 2009 Open Dent J pmid:19444340
Espindola AP et al. Deconvolution of complex NMR spectra in small molecules by multi frequency homonuclear decoupling (MDEC). 2009 J. Am. Chem. Soc. pmid:19845379
Wilson N et al. Misperceptions of "light" cigarettes abound: national survey data. 2009 BMC Public Health pmid:19426502
Pongs O TREKing noxious thermosensation. 2009 EMBO J. pmid:19421163
Masamoto Y et al. Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice. 2009 Biosci. Biotechnol. Biochem. pmid:19420725
Gannu R et al. Optimization of hydrogels for transdermal delivery of lisinopril by Box-Behnken statistical design. 2009 AAPS PharmSciTech pmid:19399627
Lechner SG et al. Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development. 2009 EMBO J. pmid:19322198
Park EJ et al. Menthol Enhances an Antiproliferative Activity of 1alpha,25-Dihydroxyvitamin D(3) in LNCaP Cells. 2009 J Clin Biochem Nutr pmid:19308266
Du J et al. Expression of TRPM8 in the distal cerebrospinal fluid-contacting neurons in the brain mesencephalon of rats. 2009 Cerebrospinal Fluid Res pmid:19292918
Orio P et al. Characteristics and physiological role of hyperpolarization activated currents in mouse cold thermoreceptors. 2009 J. Physiol. (Lond.) pmid:19273581
Persson AK et al. Correlational analysis for identifying genes whose regulation contributes to chronic neuropathic pain. 2009 Mol Pain pmid:19228393
St Charles FK et al. Post-puff respiration measures on smokers of different tar yield cigarettes. 2009 Inhal Toxicol pmid:19225967
Lee K et al. The strategic targeting of females by transnational tobacco companies in South Korea following trade liberalization. 2009 Global Health pmid:19183443
Morenilla-Palao C et al. Lipid raft segregation modulates TRPM8 channel activity. 2009 J. Biol. Chem. pmid:19176480
Chen J et al. Pore dilation occurs in TRPA1 but not in TRPM8 channels. 2009 Mol Pain pmid:19159452
Inouye S et al. Inhibitory activity of hydrosols, herbal teas and related essential oils against filament formation and the growth of Candida albicans. 2009 Nihon Ishinkin Gakkai Zasshi pmid:19942796
Iriti M and Faoro F Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. 2009 Int J Mol Sci pmid:20111684
Faria JM et al. Biotransformation of menthol and geraniol by hairy root cultures of Anethum graveolens: effect on growth and volatile components. 2009 Biotechnol. Lett. pmid:19205895
Kigasawa K et al. In vivo transdermal delivery of diclofenac by ion-exchange iontophoresis with geraniol. 2009 Biol. Pharm. Bull. pmid:19336905
Nunes IS et al. Menthol and geraniol biotransformation and glycosylation capacity of Levisticum officinale hairy roots. 2009 Planta Med. pmid:19156598
Bajtarevic A et al. Noninvasive detection of lung cancer by analysis of exhaled breath. 2009 BMC Cancer pmid:19788722
Rafati H et al. Quality by design: optimization of a liquid filled pH-responsive macroparticles using Draper-Lin composite design. 2009 J Pharm Sci pmid:19226624
Pedretti A et al. Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features. 2009 Biochim. Biophys. Acta pmid:19230823
Elmhalli FH et al. Acaricidal effects of Corymbia citriodora oil containing para-menthane-3,8-diol against nymphs of Ixodes ricinus (Acari: Ixodidae). 2009 Exp. Appl. Acarol. pmid:19169833
Heck JD Smokers of menthol and nonmenthol cigarettes exhibit similar levels of biomarkers of smoke exposure. 2009 Cancer Epidemiol. Biomarkers Prev. pmid:19190153
Jiang CH et al. Gating of the micturition reflex by tonic activation of bladder cold receptors in the cat. 2009 Neurourol. Urodyn. pmid:19260088
Hofmann D [Is inhalation therapy for bacterial bronchitis obsolete?]. 2009 Med Monatsschr Pharm pmid:19263915
Patel NA et al. Formulation and evaluation of curcumin gel for topical application. 2009 Pharm Dev Technol pmid:18821270
Songkro S et al. Effects of some terpenes on the in vitro permeation of LHRH through newborn pig skin. 2009 Pharmazie pmid:19320284
Wrigley PJ et al. Primary afferents with TRPM8 and TRPA1 profiles target distinct subpopulations of rat superficial dorsal horn neurones. 2009 Br. J. Pharmacol. pmid:19371346
Johnson CD et al. Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone. 2009 Am. J. Physiol. Heart Circ. Physiol. pmid:19363131
Flühr K et al. Capsaicin or menthol sensitization induces quantitative but no qualitative changes to thermal and mechanical pain thresholds. 2009 Clin J Pain pmid:19333158
Lv W et al. Helical fibrous nanostructures self-assembled from metal-free phthalocyanine with peripheral chiral menthol units. 2009 Chemphyschem pmid:19768721
Godavarthy SS et al. Design of improved permeation enhancers for transdermal drug delivery. 2009 J Pharm Sci pmid:19697392
Daniels RL et al. Activity of the neuronal cold sensor TRPM8 is regulated by phospholipase C via the phospholipid phosphoinositol 4,5-bisphosphate. 2009 J. Biol. Chem. pmid:19019830
Alenmyr L et al. TRPV1-mediated itch in seasonal allergic rhinitis. 2009 Allergy pmid:19220220
Kim SH et al. Menthol regulates TRPM8-independent processes in PC-3 prostate cancer cells. 2009 Biochim. Biophys. Acta pmid:18955132
Parnas M et al. Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels. 2009 Cell Calcium pmid:19135721
Muscat JE et al. Effects of menthol on tobacco smoke exposure, nicotine dependence, and NNAL glucuronidation. 2009 Cancer Epidemiol. Biomarkers Prev. pmid:19124478
Kühn FJ et al. Inhibition of TRPM8 by icilin distinct from desensitization induced by menthol and menthol derivatives. 2009 J. Biol. Chem. pmid:19095656
Randich A et al. Ice water testing reveals hypersensitivity in adult rats that experienced neonatal bladder inflammation: implications for painful bladder syndrome/interstitial cystitis. 2009 J. Urol. pmid:19447422
Smith ES and Lewin GR Nociceptors: a phylogenetic view. 2009 J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. pmid:19830434
Zhao L et al. Effect of O-acylmenthol and salt formation on the skin permeation of diclofenac acid. 2009 Drug Dev Ind Pharm pmid:19466898
Watanabe H et al. Effect of l-menthol on the thermotropic behavior of ceramide 2/cholesterol mixtures as a model for the intercellular lipids in stratum corneum. 2009 Colloids Surf B Biointerfaces pmid:19505808
Zakharian E et al. Inorganic polyphosphate modulates TRPM8 channels. 2009 PLoS ONE pmid:19404398
Saint-Eve A et al. Influence of composition (CO2 and sugar) on aroma release and perception of mint-flavored carbonated beverages. 2009 J. Agric. Food Chem. pmid:19514724
Gohel MC and Nagori SA Fabrication and design of transdermal fluconazole spray. 2009 Pharm Dev Technol pmid:19519193
Esmaeili A et al. Biotransformation of one monoterpene by sporulated surface cultures of Aspergillus niger and Penicillium sp. 2009 Nat. Prod. Res. pmid:19521921
Al-Bayati FA Isolation and identification of antimicrobial compound from Mentha longifolia L. leaves grown wild in Iraq. 2009 Ann. Clin. Microbiol. Antimicrob. pmid:19523224
Schulz K et al. Headspace solid-phase microextraction-gas chromatography-mass spectrometry determination of the characteristic flavourings menthone, isomenthone, neomenthol and menthol in serum samples with and without enzymatic cleavage to validate post-offence alcohol drinking claims. 2009 Anal. Chim. Acta pmid:19523566
Mandadi S et al. Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels. 2009 Neuroscience pmid:19482068
Chai G et al. [Effect of borneol/mentholum eutectic mixture on nasal-brain delivery of neurotoxin loaded nanoparticles]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19624007
Uyar T et al. Electrospinning of functional poly(methyl methacrylate) nanofibers containing cyclodextrin-menthol inclusion complexes. 2009 Nanotechnology pmid:19420480
The common cold. 2009 Prescrire Int pmid:19391294
Vicks Vapo-Rub--How dangerous for children? 2009 Child Health Alert pmid:19378371
Song YH et al. The effects of terpenes on the permeation of lidocaine and ofloxacin from moisture-activated patches. 2009 Drug Deliv pmid:19267298
Chantasart D et al. Effects of oxygen-containing terpenes as skin permeation enhancers on the lipoidal pathways of human epidermal membrane. 2009 J Pharm Sci pmid:19156845
Filippov IB et al. [Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol]. 2009 Fiziol Zh pmid:20201386
Gohel M and Nagori SA Fabrication and evaluation of captopril modified-release oral formulation. 2009 Pharm Dev Technol pmid:19883258