(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Menthol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Pertusa M et al. Bidirectional modulation of thermal and chemical sensitivity of TRPM8 channels by the initial region of the N-terminal domain. 2014 J. Biol. Chem. pmid:24917670
Curtin GM et al. Primary measures of dependence among menthol compared to non-menthol cigarette smokers in the United States. 2014 Regul. Toxicol. Pharmacol. pmid:24852490
da Silveira NS et al. The aversive, anxiolytic-like, and verapamil-sensitive psychostimulant effects of pulegone. 2014 Biol. Pharm. Bull. pmid:24790000
Lewis M et al. Tobacco control environment in the United States and individual consumer characteristics in relation to continued smoking: differential responses among menthol smokers? 2014 Prev Med pmid:24780527
Klein AH et al. Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses. 2014 Neuroscience pmid:24759772
Frost-Pineda K et al. Predictors, indicators, and validated measures of dependence in menthol smokers. 2014 J Addict Dis pmid:24738914
Shang L et al. An explanation for the difference in the percutaneous penetration behavior of tamsulosin induced by two different O-acylmenthol derivatives. 2014 AAPS PharmSciTech pmid:24659001
Teliban A et al. Responses of intact and injured sural nerve fibers to cooling and menthol. 2014 J. Neurophysiol. pmid:24572095
Wackowski OA et al. Young adults' behavioral intentions surrounding a potential menthol cigarette ban. 2014 Nicotine Tob. Res. pmid:24514070
Lau BK et al. Menthol enhances phasic and tonic GABAA receptor-mediated currents in midbrain periaqueductal grey neurons. 2014 Br. J. Pharmacol. pmid:24460753
Hickman NJ et al. Menthol use among smokers with psychological distress: findings from the 2008 and 2009 National Survey on Drug Use and Health. 2014 Tob Control pmid:22821797
Zhang Y et al. Effects of caffeine and menthol on cognition and mood during simulated firefighting in the heat. 2014 Appl Ergon pmid:23891504
Mizuno K et al. Goshajinkigan, a traditional Japanese medicine, prevents oxaliplatin-induced acute peripheral neuropathy by suppressing functional alteration of TRP channels in rat. 2014 J. Pharmacol. Sci. pmid:24784702
Xu P et al. Mosquito odorant receptor for DEET and methyl jasmonate. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25349401
Hu X et al. Effects of d-menthol stress on the growth of and microcystin release by the freshwater cyanobacterium Microcystis aeruginosa FACHB-905. 2014 Chemosphere pmid:25065786
Jiang J et al. Mechanistic investigation and reversible effect of 2-isopropyl-5-methylcyclohexyl heptanoate on the in vitro percutaneous absorption of indomethacin. 2014 Drug Deliv pmid:24134638
Azagba S and Sharaf MF Binge drinking and marijuana use among menthol and non-menthol adolescent smokers: findings from the youth smoking survey. 2014 Addict Behav pmid:24369112
Rossato M et al. Human white adipocytes express the cold receptor TRPM8 which activation induces UCP1 expression, mitochondrial activation and heat production. 2014 Mol. Cell. Endocrinol. pmid:24342393
Rozza AL et al. The gastroprotective effect of menthol: involvement of anti-apoptotic, antioxidant and anti-inflammatory activities. 2014 PLoS ONE pmid:24466200
Terada Y et al. Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree. 2014 J. Nat. Prod. pmid:24484240
Iovinella I et al. A rationale to design longer lasting mosquito repellents. 2014 Parasitol. Res. pmid:24599300
Rostron B Menthol cigarette use and stroke risk among US smokers: a critical reappraisal. 2014 JAMA Intern Med pmid:24614962
Sun J et al. Activation of cold-sensing transient receptor potential melastatin subtype 8 antagonizes vasoconstriction and hypertension through attenuating RhoA/Rho kinase pathway. 2014 Hypertension pmid:24637663
Reinsperger T and Luy B Homonuclear BIRD-decoupled spectra for measuring one-bond couplings with highest resolution: CLIP/CLAP-RESET and constant-time-CLIP/CLAP-RESET. 2014 J. Magn. Reson. pmid:24365099
Menger DJ et al. A push-pull system to reduce house entry of malaria mosquitoes. 2014 Malar. J. pmid:24674451
Mirokuji Y et al. The JFFMA assessment of flavoring substances structurally related to menthol and uniquely used in Japan. 2014 Food Chem. Toxicol. pmid:24309148
Anderson EM et al. The effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment device. 2014 PLoS ONE pmid:24558480
Ribeiro JC et al. Efficacy of free and nanoencapsulated Eucalyptus citriodora essential oils on sheep gastrointestinal nematodes and toxicity for mice. 2014 Vet. Parasitol. pmid:24929446
Ramos-Filho AC et al. Menthol inhibits detrusor contractility independently of TRPM8 activation. 2014 PLoS ONE pmid:25375115
Pezzoli M et al. Dampened neural activity and abolition of epileptic-like activity in cortical slices by active ingredients of spices. 2014 Sci Rep pmid:25359561
Raddatz N et al. Temperature and voltage coupling to channel opening in transient receptor potential melastatin 8 (TRPM8). 2014 J. Biol. Chem. pmid:25352597
Romero MC et al. Peppermint (Mentha piperita) and albendazole against anisakiasis in an animal model. 2014 Trop. Med. Int. Health pmid:25330410
Willershausen I et al. Influence of E-smoking liquids on human periodontal ligament fibroblasts. 2014 Head Face Med pmid:25224853
Thihalolipavan S et al. Menthol smokers in large-scale nicotine replacement therapy program. 2014 Am J Public Health pmid:25211736
Low SB et al. Evaluation of a topical gel containing a novel combination of essential oils and antioxidants for reducing oral malodor in dogs. 2014 Am. J. Vet. Res. pmid:24959732
Zimmermann MH et al. Relighting behaviour among cigarette smokers seeking treatment: implications for tobacco treatment and policy. 2014 Int. J. Clin. Pract. pmid:25113663
Curtin GM et al. Measures of initiation and progression to increased smoking among current menthol compared to non-menthol cigarette smokers based on data from four U.S. government surveys. 2014 Regul. Toxicol. Pharmacol. pmid:25111576
Patel R et al. Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a comparison with topical menthol. 2014 Pain pmid:25083927
Sulsky SI et al. Evaluating the association between menthol cigarette use and the likelihood of being a former versus current smoker. 2014 Regul. Toxicol. Pharmacol. pmid:25017361
Curtin GM et al. Patterns of menthol cigarette use among current smokers, overall and within demographic strata, based on data from four U.S. government surveys. 2014 Regul. Toxicol. Pharmacol. pmid:24997230
Kasza KA et al. Switching between menthol and nonmenthol cigarettes: findings from the U.S. Cohort of the International Tobacco Control Four Country Survey. 2014 Nicotine Tob. Res. pmid:24984878
Chen GY et al. [Decreased amplitude of [Ca²⁺]i elevation induced by menthol in pulmonary arterial smooth muscle cells of pulmonary hypertensive rats]. 2014 Sheng Li Xue Bao pmid:24964842
Minaker LM et al. Flavored tobacco use among Canadian students in grades 9 through 12: prevalence and patterns from the 2010-2011 youth smoking survey. 2014 Prev Chronic Dis pmid:24945240
Smith SS et al. Smoking cessation in smokers who smoke menthol and non-menthol cigarettes. 2014 Addiction pmid:24938369
Topp R et al. Topical menthol, ice, peripheral blood flow, and perceived discomfort. 2013 Mar-Apr J Athl Train pmid:23672386
Pereira EJ et al. The effect of inhaled menthol on upper airway resistance in humans: a randomized controlled crossover study. 2013 Jan-Feb Can. Respir. J. pmid:23457678
Topp R et al. The effect of either topical menthol or a placebo on functioning and knee pain among patients with knee OA. 2013 Apr-Jun J Geriatr Phys Ther pmid:22976810
Selescu T et al. Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin. 2013 Chem. Senses pmid:23828908
Vetter I et al. Amplified cold transduction in native nociceptors by M-channel inhibition. 2013 J. Neurosci. pmid:24133266
Winhusen TM et al. A tale of two stimulants: mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence. 2013 Drug Alcohol Depend pmid:24075226