| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Uveitis, Posterior | D015866 | 5 associated lipids |
Total
3
(-)-Menthol
(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.
Cross Reference
Introduction
To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Menthol?
(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Menthol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Menthol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Menthol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (-)-Menthol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Menthol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (-)-Menthol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Menthol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Menthol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Samad A et al. | The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1. | 2011 | Biochem. J. | pmid:20946100 |
| Hohenwallner W and Klima J | In vivo activation of glucuronyl transferase in rat liver by eucalyptole. | 1971 | Biochem. Pharmacol. | pmid:5132892 |
| Jori A et al. | Effect of essential oils on drug metabolism. | 1969 | Biochem. Pharmacol. | pmid:5345885 |
| Austin CA et al. | The effect of terpenoid compounds on cytochrome P-450 levels in rat liver. | 1988 | Biochem. Pharmacol. | pmid:3377821 |
| Liu K et al. | NPPB structure-specifically activates TRPA1 channels. | 2010 | Biochem. Pharmacol. | pmid:20226176 |
| Rath P et al. | Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain. | 2016 | Biochemistry | pmid:26653082 |
| Bouchard M et al. | Membrane fluidity response to odorants as seen by 2H-NMR and infrared spectroscopy. | 1996 | Biochim. Biophys. Acta | pmid:8703978 |
| Persaud KC et al. | Ion transport across the frog olfactory mucosa: the basal and odorant-stimulated states. | 1987 | Biochim. Biophys. Acta | pmid:2440480 |
| Cortright DN et al. | TRP channels and pain. | 2007 | Biochim. Biophys. Acta | pmid:17467247 |
| Turina AV et al. | Monoterpenes affect chlorodiazepoxide-micelle interaction through micellar dipole potential modifications. | 2003 | Biochim. Biophys. Acta | pmid:14561468 |
| Pedretti A et al. | Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features. | 2009 | Biochim. Biophys. Acta | pmid:19230823 |
| Chen H et al. | A combination of site-directed mutagenesis and chemical modification to improve diastereopreference of Pseudomonas alcaligenes lipase. | 2013 | Biochim. Biophys. Acta | pmid:24012560 |
| Kim SH et al. | Menthol regulates TRPM8-independent processes in PC-3 prostate cancer cells. | 2009 | Biochim. Biophys. Acta | pmid:18955132 |
| Trudgill PW | Microbial metabolism of monoterpenes--recent developments. | 1990 | Biodegradation | pmid:1368150 |
| da Silveira NS et al. | The aversive, anxiolytic-like, and verapamil-sensitive psychostimulant effects of pulegone. | 2014 | Biol. Pharm. Bull. | pmid:24790000 |
| Hendradi E et al. | Effect of mixed micelle formulations including terpenes on the transdermal delivery of diclofenac. | 2003 | Biol. Pharm. Bull. | pmid:14646182 |
| Li CJ et al. | Promoting mechanism of menthol derivative, 1-O-ethyl-3-buthylcyclohexanol, on the percutaneous absorption of ketoprofen. | 2001 | Biol. Pharm. Bull. | pmid:11558566 |
| Morimoto Y et al. | In vitro skin permeation of morphine hydrochloride during the finite application of penetration-enhancing system containing water, ethanol and l-menthol. | 2002 | Biol. Pharm. Bull. | pmid:11824544 |
| Kigasawa K et al. | In vivo transdermal delivery of diclofenac by ion-exchange iontophoresis with geraniol. | 2009 | Biol. Pharm. Bull. | pmid:19336905 |
| Duangjit S et al. | Menthosomes, novel ultradeformable vesicles for transdermal drug delivery: optimization and characterization. | 2012 | Biol. Pharm. Bull. | pmid:23037161 |
| Hoshino M et al. | Effects of menthol on the pharmacokinetics of triazolam and phenytoin. | 2015 | Biol. Pharm. Bull. | pmid:25757928 |
| Kakubari I et al. | Formulation and evaluation of ethylene-vinyl acetate copolymer matrix patches containing formoterol fumarate. | 2006 | Biol. Pharm. Bull. | pmid:16508156 |
| Matsui R et al. | Combination effect of physical and gustatory taste masking for propiverine hydrochloride orally disintegrating tablets on palatability. | 2015 | Biol. Pharm. Bull. | pmid:25744453 |
| Morimoto Y et al. | Effect of l-menthol-ethanol-water system on the systemic absorption of flurbiprofen after repeated topical applications in rabbits. | 2000 | Biol. Pharm. Bull. | pmid:11041263 |
| Kobayashi D et al. | Feasibility of use of several cardiovascular agents in transdermal therapeutic systems with l-menthol-ethanol system on hairless rat and human skin. | 1993 | Biol. Pharm. Bull. | pmid:8364469 |
| Obata Y et al. | Effect of pretreatment of skin with cyclic monoterpenes on permeation of diclofenac in hairless rat. | 1993 | Biol. Pharm. Bull. | pmid:8364480 |
| Ditrichova D et al. | Oral lichenoid lesions and allergy to dental materials. | 2007 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | pmid:18345274 |
| Lin R et al. | Analysis of menthol in three traditional Chinese medicinal herbs and their compound formulation by GC-MS. | 2002 | Biomed. Chromatogr. | pmid:11920950 |
| SantamarÃa E et al. | [Field efficacy of repellent formulation containing para-menthane-3,8-diol and lemongrass against Culicoides pachymerus (Diptera: Ceratopogonidae) in Colombia]. | 2012 | Biomedica | pmid:23715194 |
| Ortar G et al. | (-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20378345 |
| DeFalco J et al. | 5-benzyloxytryptamine as an antagonist of TRPM8. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20965726 |
| Li S et al. | Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cells. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24210499 |
| Narishetty ST and Panchagnula R | Transdermal delivery system for zidovudine: in vitro, ex vivo and in vivo evaluation. | 2004 | Biopharm Drug Dispos | pmid:14716748 |
| Jain AK and Panchagnula R | Transdermal delivery of imipramine hydrochloride: development and evaluation (in vitro and in vivo) of reservoir gel formulation. | 2005 | Biopharm Drug Dispos | pmid:15614831 |
| Cal K | Skin disposition of menthol after its application in the presence of drug substances. | 2008 | Biopharm Drug Dispos | pmid:18985797 |
| Nagatomo K et al. | The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppression. | 2010 | Biophys. J. | pmid:21112285 |
| Yamamoto H and Hayakawa T | Syntheses of poly[beta-(l)-menthyl D- and L-aspartates] and their secondary structures. | 1971 | Biopolymers | pmid:5545525 |
| Gupta ML et al. | Effect of the vesicular-arbuscular mycorrhizal (VAM) fungus Glomus fasciculatum on the essential oil yield related characters and nutrient acquisition in the crops of different cultivars of menthol mint (Mentha arvensis) under field conditions. | 2002 | Bioresour. Technol. | pmid:11708758 |
| Ram D et al. | Optimization of water and nitrogen application to menthol mint (Mentha arvensis L.) through sugarcane trash mulch in a sandy loam soil of semi-arid subtropical climate. | 2006 | Bioresour. Technol. | pmid:16005209 |
| Li Z et al. | Dual response surface-optimized synthesis of L-menthyl conjugated linoleate in solvent-free system by Candida rugosa lipase. | 2010 | Bioresour. Technol. | pmid:19833506 |
| Miyazawa M and Nakanishi K | Biotransformation of (-)-menthone by human liver microsomes. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16717432 |
| Shimizu K et al. | Essential oil of lavender inhibited the decreased attention during a long-term task in humans. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18603803 |
| Nakagawa H et al. | Anomer-selective glucosylation of l-menthol by yeast alpha-glucosidase. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9720215 |
| Masamoto Y et al. | Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19420725 |
| Sassa T et al. | (+)-Menthol and its hydroxy derivatives, novel fungal monoterpenols from the fusicoccin-producing fungi, Phomopsis amygdali F6a and Niigata 2. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12723593 |
| Nagamatsu R et al. | Cleavage of α-dicarbonyl compounds by terpene hydroperoxide. | 2012 | Biosci. Biotechnol. Biochem. | pmid:23047102 |
| Kawasaki H et al. | Intake of dried bonito broth flavored with dextrin solution induced conditioned place preference in mice. | 2011 | Biosci. Biotechnol. Biochem. | pmid:22146712 |
| Liu XD et al. | Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying. | 2000 | Biosci. Biotechnol. Biochem. | pmid:10993145 |
| Szymańska I et al. | Fullerene modified supported lipid membrane as sensitive element of sensor for odorants. | 2001 | Biosens Bioelectron | pmid:11679270 |
| Braiuca P et al. | BESSICC, a COSMO-RS based tool for in silico solvent screening of biocatalyzed reactions. | 2012 | Biotechnol. Bioeng. | pmid:22252881 |
| Faria JM et al. | Biotransformation of menthol and geraniol by hairy root cultures of Anethum graveolens: effect on growth and volatile components. | 2009 | Biotechnol. Lett. | pmid:19205895 |
| Cinelli G et al. | Use of Rhodotorula minuta live cells hosted in water-in-oil macroemulsion for biotrasformation reaction. | 2006 May-Jun | Biotechnol. Prog. | pmid:16739950 |
| Shotipruk A et al. | Feasibility study of repeated harvesting of menthol from biologically viable Mentha x piperata using ultrasonic extraction. | 2001 Sep-Oct | Biotechnol. Prog. | pmid:11587585 |
| Ito H et al. | Functional role of the transient receptor potential melastatin 8 (TRPM8) ion channel in the urinary bladder assessed by conscious cystometry and ex vivo measurements of single-unit mechanosensitive bladder afferent activities in the rat. | 2016 | BJU Int. | pmid:26189966 |
| Skogerson K et al. | The volatile compound BinBase mass spectral database. | 2011 | BMC Bioinformatics | pmid:21816034 |
| Brady D et al. | Spherezymes: a novel structured self-immobilisation enzyme technology. | 2008 | BMC Biotechnol. | pmid:18237402 |
| Chodon D et al. | Estrogen regulation of TRPM8 expression in breast cancer cells. | 2010 | BMC Cancer | pmid:20482834 |
| Rollison DE et al. | Case-control study of tobacco smoke exposure and breast cancer risk in Delaware. | 2008 | BMC Cancer | pmid:18518960 |
| Bajtarevic A et al. | Noninvasive detection of lung cancer by analysis of exhaled breath. | 2009 | BMC Cancer | pmid:19788722 |
| Mendelson JE et al. | The clinical pharmacology of intranasal l-methamphetamine. | 2008 | BMC Clin Pharmacol | pmid:18644153 |
| Tyagi AK and Malik A | Liquid and vapour-phase antifungal activities of selected essential oils against Candida albicans: microscopic observations and chemical characterization of Cymbopogon citratus. | 2010 | BMC Complement Altern Med | pmid:21067604 |
| Ahameethunisa AR and Hopper W | Antibacterial activity of Artemisia nilagirica leaf extracts against clinical and phytopathogenic bacteria. | 2010 | BMC Complement Altern Med | pmid:20109237 |
| Marcos-Arias C et al. | In vitro activities of natural products against oral Candida isolates from denture wearers. | 2011 | BMC Complement Altern Med | pmid:22118215 |
| Cane R et al. | Understanding childhood asthma in focus groups: perspectives from mothers of different ethnic backgrounds. | 2001 | BMC Fam Pract | pmid:11667951 |
| Medbø A et al. | "I did not intend to stop. I just could not stand cigarettes any more." A qualitative interview study of smoking cessation among the elderly. | 2011 | BMC Fam Pract | pmid:21627833 |
| Deluc LG et al. | Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development. | 2007 | BMC Genomics | pmid:18034876 |
| Faseru B et al. | Design, recruitment, and retention of African-American smokers in a pharmacokinetic study. | 2010 | BMC Med Res Methodol | pmid:20085641 |
| Warner JH et al. | Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers. | 2010 | BMC Med Res Methodol | pmid:20233412 |
| Raja AF et al. | Antistaphylococcal and biofilm inhibitory activities of acetyl-11-keto-β-boswellic acid from Boswellia serrata. | 2011 | BMC Microbiol. | pmid:21406118 |
| Niu NN et al. | Patient disease perceptions and coping strategies for arthritis in a developing nation: a qualitative study. | 2011 | BMC Musculoskelet Disord | pmid:21985605 |
| Facer P et al. | Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. | 2007 | BMC Neurol | pmid:17521436 |
| Suzuki M et al. | The odor stick identification test for Japanese differentiates Parkinson's disease from multiple system atrophy and progressive supra nuclear palsy. | 2011 | BMC Neurol | pmid:22192419 |
| Damann N et al. | Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing. | 2006 | BMC Neurosci | pmid:16762059 |
| Su L et al. | Role of TRPM8 in dorsal root ganglion in nerve injury-induced chronic pain. | 2011 | BMC Neurosci | pmid:22111979 |
| Ly KA et al. | Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial [ISRCTN43479664]. | 2006 | BMC Oral Health | pmid:16556326 |
| Panitz D et al. | A C. elegans model of electronic cigarette use: Physiological effects of e-liquids in nematodes. | 2015 | BMC Pharmacol Toxicol | pmid:26637209 |
| Fortes AM et al. | Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening. | 2011 | BMC Plant Biol. | pmid:22047180 |
| Haskins AE et al. | Smoking during pregnancy and risk of abnormal glucose tolerance: a prospective cohort study. | 2010 | BMC Pregnancy Childbirth | pmid:20849607 |
| Faseru B et al. | A longitudinal study of tobacco use among American Indian and Alaska Native tribal college students. | 2010 | BMC Public Health | pmid:20955575 |
| Wilson N et al. | Misperceptions of "light" cigarettes abound: national survey data. | 2009 | BMC Public Health | pmid:19426502 |
| Poston WS et al. | Menthol cigarette pricing at military and community retail outlets in the United States. | 2012 | BMC Public Health | pmid:22938755 |
| Fix BV et al. | Smokers' reactions to FDA regulation of tobacco products: findings from the 2009 ITC United States survey. | 2011 | BMC Public Health | pmid:22177316 |
| D'Ruiz CD et al. | Nicotine delivery, tolerability and reduction of smoking urge in smokers following short-term use of one brand of electronic cigarettes. | 2015 | BMC Public Health | pmid:26424091 |
| Nakkash RT et al. | The rise in narghile (shisha, hookah) waterpipe tobacco smoking: a qualitative study of perceptions of smokers and non smokers. | 2011 | BMC Public Health | pmid:21569577 |
| Lee PN | Systematic review of the epidemiological evidence comparing lung cancer risk in smokers of mentholated and unmentholated cigarettes. | 2011 | BMC Pulm Med | pmid:21501470 |
| Mukerji G et al. | Pain during ice water test distinguishes clinical bladder hypersensitivity from overactivity disorders. | 2006 | BMC Urol | pmid:17192176 |
| Mukerji G et al. | Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations. | 2006 | BMC Urol | pmid:16519806 |
| Dyer C | Tobacco firms move to stop FDA banning menthol cigarettes. | 2011 | BMJ | pmid:21363858 |
| Boyle S and Walters MR | Clinically significant interaction between warfarin and popular cough lozenges 'Fisherman's Friend'. | 2011 | BMJ Case Rep | pmid:22675107 |
| Pearson JL et al. | The Moment Study: protocol for a mixed method observational cohort study of the Alternative Nicotine Delivery Systems (ANDS) initiation process among adult cigarette smokers. | 2016 | BMJ Open | pmid:27105716 |
| Kearns GL et al. | Systemic exposure to menthol following administration of peppermint oil to paediatric patients. | 2015 | BMJ Open | pmid:26270949 |
| Cardini C et al. | [Uses of gas chromatography in pharmaceutical analysis. II. Control of some preparations for rhinotherapy]. | 1967 | Boll Chim Farm | pmid:5599309 |
| ROBUSCHI L and ZINI F | [Glucuronic conjugation of menthol following oral administration]. | 1951 Jan-Feb | Boll. Soc. Ital. Biol. Sper. | pmid:14848320 |
| ROBUSCHI L and ZINI F | [Glucuronic conjugation of menthol following parenteral administration]. | 1951 Jan-Feb | Boll. Soc. Ital. Biol. Sper. | pmid:14848321 |
| Brunner M et al. | A new topical formulation enhances relative diclofenac bioavailability in healthy male subjects. | 2011 | Br J Clin Pharmacol | pmid:21241352 |
| Somerville KW et al. | Delayed release peppermint oil capsules (Colpermin) for the spastic colon syndrome: a pharmacokinetic study. | 1984 | Br J Clin Pharmacol | pmid:6487507 |
| Ebihara T et al. | Effects of menthol on the triggering of the swallowing reflex in elderly patients with dysphagia. | 2006 | Br J Clin Pharmacol | pmid:16934054 |
| Barwood MJ et al. | Early change in thermal perception is not a driver of anticipatory exercise pacing in the heat. | 2012 | Br J Sports Med | pmid:22144003 |
| Guide to Receptors and Channels (GRAC), 4th Edition. | 2009 | Br. J. Pharmacol. | pmid:19883461 | |
| Vogt-Eisele AK et al. | Monoterpenoid agonists of TRPV3. | 2007 | Br. J. Pharmacol. | pmid:17420775 |